|
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 97.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.99500 to 0.99800 @ 20.00 °C.
|
| Pounds per Gallon - (est).: | 8.289 to 8.314
|
| Refractive Index: | 1.51100 to 1.51500 @ 20.00 °C.
|
| Melting Point: | -21.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 118.00 to 119.00 °C. @ 15.00 mm Hg
|
| Boiling Point: | 242.00 to 243.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 0.051000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 195.00 °F. TCC ( 90.56 °C. )
|
| logP (o/w): | 3.195 (est) |
| Soluble in: |
| | alcohol | | | fats | | | water, 146.9 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: burnt |
| |
| | burnt fatty meaty fungal sulfurous |
Odor Description: at 0.10 % in propylene glycol. | burnt fatty meaty fungal sulfurous |
| |
| |
| Flavor Type: burnt |
| |
| | burnt fatty meaty |
Taste Description:
| burnt fatty meaty |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| Kingchem Laboratories |
| 1, 6 HEXANEDITHIOL |
| Odor Description: | Meat, fungus, sulfur |
| |
| R C Treatt & Co Ltd |
| 1,6-Hexanedithiol Kosher |
| Taste Description: | burnt; fatty-meaty, on dilution Used in Poultry, meat, soup and other savoury flavours. Normal levels in end use: 0.005-0.2ppm. FEMA specifies that total dithiols added to a foodstuff should not exceed 1.0ppm. |
| |
| |
Cosmetic Information:
Suppliers:
| Ambles Nature et Chimie |
| 1.6-HEXANEDITHIOL
|
| Anhui Suzhou Jinli Aromatic Chemicals |
| 1,6-Hexanedithiol
Odor: meat, mushroom, sulfur |
| Beijing Lys Chemicals |
| 1,6-Hexanedithiol
|
| BOC Sciences |
| For experimental / research use only. |
| 1,6-Hexanedithiol
|
| DeLong Chemicals America |
| 1,6-Hexanedithiol, Kosher
|
| Endeavour Specialty Chemicals |
| 1,6-Hexanedithiol 98% F&F
|
| Speciality Chemical Product Groups |
| Jiangyin Healthway |
| 1,6-Hexanedithiol
|
| New functional food ingredients |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| 1,6-Hexanedithiol, Kosherk
|
| Kingchem Laboratories |
| 1, 6 HEXANEDITHIOL
Odor: Meat, fungus, sulfur |
| M&U International |
| 1,6-HEXANEDITHIOL, Kosher
|
| OQEMA |
| 1,6-Hexanedithiol
|
| Penta International |
| 1,6-HEXANEDITHIOL
|
| R C Treatt & Co Ltd |
| 1,6-Hexanedithiol
Kosher Flavor: burnt; fatty-meaty, on dilution Used in Poultry, meat, soup and other savoury flavours. Normal levels in end use: 0.005-0.2ppm. FEMA specifies that total dithiols added to a foodstuff should not exceed 1.0ppm. |
| Robinson Brothers |
| 1,6-Hexanedithiol F&F
|
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 1,6-Hexanedithiol
|
| Sigma-Aldrich |
| 1,6-Hexanedithiol, ≥97%, FG
≥97%, Kosher, FG Odor: meaty; fatty |
| Certified Food Grade Products |
| Sunaux International |
| 1,6-Hexanedithiol
|
| Synerzine |
| 1,6-Hexanedithiol
|
| TCI AMERICA |
| For experimental / research use only. |
| 1,6-Hexanedithiol >97.0%(GC)(T)
|
| Tengzhou Jitian Aroma Chemiclal |
| 1,6-Hexane Dithiol
|
| Tengzhou Xiang Yuan Aroma Chemicals |
| 1,6-Hexanedithiol
|
| Tianjin Danjun International |
| 1,6-Hexanedithiol
|
| United International |
| 1,6-Hexanedithiol
|
| WholeChem |
| 1.6-Hexanedithiol
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 100 mg/kg National Technical Information Service. Vol. AD277-689
intravenous-cat LD50 83 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: ATAXIA Journal of Pharmacology and Experimental Therapeutics. Vol. 87(Suppl), Pg. 6, 1946.
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
inhalation-mouse LC > 1490 mg/m3/10 National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. Aug, 1942.
|
Safety in Use Information:
| Category: | flavoring agents |
| Recommendation for 1,6-hexane dithiol usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 1.60 (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 10 |
| Click here to view publication 10 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 0.20000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | - |
| fruit ices: | - | - |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | 0.20000 |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 0.20000 |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | 0.20000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 14491 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | hexane-1,6-dithiol |
| Chemidplus: | 0001191431 |
| RTECS: | MO3500000 for cas# 1191-43-1 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| No odor group found for these |
|
| iso | butyl stearate | CS |
| | dioctyl malonate | |
| | ethyl 2,4,7-decatrienoate | FL/FR |
| 9- | octadecenal | FL/FR |
| | oleyl acetate | CS |
| (Z)- | oleyl alcohol | FR |
| iso | propyl myristate | CS |
| alpha- | terpinen-7-al | FL/FR |
| iso | valeraldehyde diethyl acetal | FL/FR |
| | valeraldehyde propylene glycol acetal | FL/FR |
| acidic |
| | cyclohexyl acetic acid | FL/FR |
| aldehydic |
| | acetyl nonyryl | FL/FR |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| | fresh carbaldehyde | FR |
| | green hexanal | FL/FR |
| | octane nitrile | FR |
| | TMH aldehyde | FR |
| | undecanal | FL/FR |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| iso | valeraldehyde | FL/FR |
| | dimethyl trisulfide | FL/FR |
| animal |
| | costus valerolactone | FR |
| balsamic |
| | cypress absolute | FR |
| | guaiyl acetate | FL/FR |
| | rum ether | FL/FR |
| buttery |
| | acetyl butyryl | FL/FR |
| | acetyl isobutyryl | FL/FR |
| | strawberry furanone acetate | FL/FR |
| 2- | methyl hexanoic acid | FL/FR |
| citrus |
| | aldehydic nitrile | FR |
| (E)-4- | decenal | FL/FR |
| 4- | decenal | FL/FR |
| | octanal glycol acetal | FR |
| coconut |
| delta-2- | dodecenolactone | FL/FR |
| gamma- | octalactone | FL/FR |
| delta- | octalactone | FL/FR |
| delta- | undecalactone | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| | furfuryl mercaptan | FL/FR |
| 2- | methyl-3-,5 or 6-(furfuryl thio) pyrazine | FL/FR |
| creamy |
| gamma- | butyrolactone | FL/FR |
| | methyl undecylenate | FL/FR |
| ethereal |
| | decyl propionate | FL/FR |
| fatty |
| | allyl cyclohexyl hexanoate | FL/FR |
| | allyl octanoate | FL/FR |
| | butyl stearate | FL/FR |
| iso | butyl undecylenate | FL/FR |
| | butyl undecylenate | FL/FR |
| | coconut absolute | FL/FR |
| (Z)- | dairy lactone | FL/FR |
| 2,4- | decadien-1-ol | FL/FR |
| | decanoic acid | FL/FR |
| | decanol | FL/FR |
| (E)-2- | decen-1-ol | FL/FR |
| 3- | decen-2-one | FL/FR |
| (E)-2- | decenal | FL/FR |
| 2- | decenal | FL/FR |
| 2- | dodecen-1-ol | FL/FR |
| | ethyl undecylenate | FL/FR |
| (E)-2- | hepten-1-ol | FL/FR |
| | hexanoic acid | FL/FR |
| | hexyl pivalate | FR |
| | lauric acid | FL/FR |
| | methyl 10-undecenoate | FL/FR |
| | methyl 2-hexenoate | FL/FR |
| 4- | methyl octanoic acid | FL/FR |
| | neryl acetone | FL/FR |
| (Z)-2- | nonenal | CS |
| (E)-2- | nonenal | FL/FR |
| 2- | nonenal | FL/FR |
| | octanoic acid | FL/FR |
| (Z)-3- | octen-1-ol | FL/FR |
| 2- | octenal | FL/FR |
| (E)-2- | octenal | FL/FR |
| (Z)- | oleic acid | FL/FR |
| | perilla seed oil | FL/FR |
| (E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
| 2,4- | undecadien-1-ol | FR |
| | undecanal propylene glycol acetal | FL/FR |
| 10- | undecen-2-one | FL/FR |
| floral |
| alpha- | amyl cinnamaldehyde / methyl anthranilate schiff's base | FR |
| | benzyl lactate | FL/FR |
| | decanal / methyl anthranilate schiff's base | FR |
| | jasmin absolute (from pommade) | FL/FR |
| | nonanol | FL/FR |
| | octanal / methyl anthranilate schiff's base | FR |
| | orris rhizome concrete butter (iris pallida) | FL/FR |
| | terpinyl isobutyrate | FL/FR |
| fresh |
| | decyl vinyl ether | FR |
| fried |
| (E,Z)-2,4- | decadienal | |
| fruity |
| | allyl cyclohexyl propionate | FL/FR |
| | allyl hexanoate | FL/FR |
| | amyl hexanoate | FL/FR |
| gamma- | dodecalactone | FL/FR |
| | ethyl acetoacetate | FL/FR |
| | ethyl hexanoate | FL/FR |
| (E)-2- | hepten-1-yl acetate | FL/FR |
| | methyl 2-methyl butyrate | FL/FR |
| | octen-1-yl cyclopentanone | FL/FR |
| | octyl heptanoate | FL/FR |
| | propyl 2,4-decadienoate | FL/FR |
| | strawberry glycidate 1 (aldehyde C-16 (so-called)) | FL/FR |
| | tropical trithiane | FL/FR |
| gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| 2- | undecanone | FL/FR |
| 3,7- | dimethyl-6-octenoic acid | FL/FR |
| | dodecanal dimethyl acetal | FL/FR |
| | heptanal cyclic propylene acetal | FL/FR |
| 3- | heptanone | FL/FR |
| (Z)-4- | heptenal | FL/FR |
| 2- | heptenal | FL/FR |
| (Z)-4- | heptenal diethyl acetal | FL/FR |
| 2- | heptyl furan | FL/FR |
| | hexanal (aldehyde C-6) | FL/FR |
| (E)-3- | hexen-1-ol | FL/FR |
| (Z)-3- | hexen-1-yl benzoate | FL/FR |
| (Z)-3- | hexen-1-yl pyruvate | FL/FR |
| (E)-2- | hexenal | FL/FR |
| alpha- | hexyl cinnamaldehyde dimethyl acetal | FR |
| | manzanate (Givaudan) | FL/FR |
| | neryl butyrate | FL/FR |
| (E,Z)-3,6- | nonadien-1-ol | FL/FR |
| (E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| (E,Z)-2,6- | nonadienal | FL/FR |
| | octanal diethyl acetal | FL/FR |
| (E)-2- | octen-1-yl acetate | FL/FR |
| | perilla alcohol | FL/FR |
| herbal |
| | benzyl octanoate | FL/FR |
| laevo- | perillaldehyde | FL/FR |
| | meaty dithiane | FL/FR |
| 4- | methyl nonanoic acid | FL/FR |
| | sulfurol | FL/FR |
| | sulfuryl acetate | FL/FR |
| melon |
| (Z)-6- | nonen-1-ol | FL/FR |
| musk |
| | exaltone (Firmenich) | FR |
| dextro,laevo- | muscone | FL/FR |
| | hazelnut pyrazine | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| oily |
| | petal pyranone | FL/FR |
| popcorn |
| 2- | acetyl pyridine | FL/FR |
| soapy |
| | benzyl laurate | FL/FR |
| | ethyl undecanoate | FL/FR |
| spicy |
| | allspice leaf oil | FL/FR |
| | cumin seed oil | FL/FR |
| | gingergrass oil | FR |
| 2- | octanol | FL/FR |
| | benzothiazole | FL/FR |
| | ethyl 3-mercaptopropionate | FL/FR |
| | fish thiol | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| 1- | phenethyl mercaptan | FL/FR |
| tobacco |
| | methyl benzoxole | FL/FR |
| tonka |
| 6- | amyl-alpha-pyrone | FL/FR |
| waxy |
| iso | amyl laurate | FL/FR |
| (Z)-5- | decen-1-ol | |
| (E)-2- | decen-1-yl acetate | FL/FR |
| 9- | decenoic acid | FL/FR |
| 1- | dodecanol | FL/FR |
| | methyl myristate | FL/FR |
| | methyl undecanoate | FR |
| | myristic acid | FL/FR |
| 2,4- | nonadien-1-ol | FL/FR |
| | octanol | FL/FR |
| | octyl isobutyrate | FL/FR |
| | palmitic acid | FR |
| delta- | tetradecalactone | FL/FR |
| | tetradecanal | FL/FR |
| | undecanoic acid | FL/FR |
| woody |
| | amber carbinol | FR |
| | amyris acetate | FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| 4- | acetyl-2-methyl pyrimidine | FL |
| | allyl cyclohexyl hexanoate | FL/FR |
| gamma- | aminobutyric acid | FL |
| | amyl mercaptan | FL |
| | benzyl lactate | FL/FR |
| | benzyl octanoate | FL/FR |
| 1,2- | butane dithiol | FL |
| | butyl stearate | FL/FR |
| iso | butyl undecylenate | FL/FR |
| 2-(2- | butyl)-4,5-dimethyl-3-thiazoline | FL |
| | cyclopropyl (E,Z)-2,6-nonadienamide | FL |
| (E,Z)-2,4- | decadienal | |
| 3-oxo | decanoic acid glyceride | FL |
| (Z)-5- | decen-1-ol | |
| (E)-2- | decen-1-ol | FL/FR |
| (E)-2- | decen-1-yl acetate | FL/FR |
| 4- | decenal | FL/FR |
| 2- | decenoic acid | FL |
| | decyl propionate | FL/FR |
| 2,5- | diethyl thiazole | FL |
| | dimethyl tetrasulfide | FL |
| 2,6- | dimethyl-3-((2-methyl-3-furyl)thio)-4-heptanone | FL |
| bis(2,5- | dimethyl-3-furyl) disulfide | FL |
| (Z+E)-2,5- | dimethyl-3-tetrahydrofuran thiol | FL |
| (Z+E)-2,5- | dimethyl-3-thioacetoxytetrahydrofuran | FL |
| 2,5- | dimethyl-3-thiofuroyl furan | FL |
| | dioctyl malonate | |
| 3-oxo | dodecanoic acid glyceride | FL |
| (E)-2- | dodecen-1-ol | FL |
| 2- | dodecen-1-ol | FL/FR |
| (E)-2- | dodecen-1-yl acetate | FL |
| 11- | dodecenoic acid | FL |
| delta-2- | dodecenolactone | FL/FR |
| | elecampane root absolute | FL |
| | epoxy-2-decenal | FL |
| 2,3- | epoxydecanal | FL |
| 2,3- | epoxyheptanal | FL |
| | ethyl (E,Z)-2,6-nonadienamide | FL |
| S- | ethyl 2-acetyl aminoethane thioate | FL |
| | ethyl 2,4,7-decatrienoate | FL/FR |
| | ethyl 3-mercaptopropionate | FL/FR |
| | ethyl 4-(acetyl thio) butyrate | FL |
| (Z+E)-5- | ethyl-4-methyl-2-(2-butyl) thiazoline | FL |
| (Z+E)-5- | ethyl-4-methyl-2-(2-methyl propyl) thiazoline | FL |
| | furfuryl hexanoate | FL |
| | guaiyl acetate | FL/FR |
| | heptanal cyclic propylene acetal | FL/FR |
| (E)-2- | hepten-1-ol | FL/FR |
| (E)-2- | hepten-1-yl acetate | FL/FR |
| 2- | heptenal | FL/FR |
| 3-oxo | hexadecanoic acid glyceride (palm oil glycerides mono- and di- hydrogenated) | FL |
| | hexanal butane-2,3-diol acetal | FL |
| | hexanal octane-1,3-diol acetal | FL |
| 3-oxo | hexanoic acid glyceride | FL |
| | hexyl (E)-2-hexenoate | FL |
| | lauric acid | FL/FR |
| | methionyl acetate | FL |
| | methyl 2-hexenoate | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| | methyl dihydrofuran thiol | FL |
| 5- | methyl hexanoic acid | FL |
| | methyl myristate | FL/FR |
| 2- | methyl thiazolidine | FL |
| 2-( | methyl thio) ethanol | FL |
| 3- | methyl-2-cyclopenten-1-one | FL |
| 2- | methyl-3-,5 or 6-(furfuryl thio) pyrazine | FL/FR |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| 2- | methyl-3-furyl tetrasulfide | FL |
| 3-((2- | methyl-3-furyl)thio)-4-heptanone | FL |
| 4-((2- | methyl-3-furyl)thio)-5-nonanone | FL |
| | neryl acetone | FL/FR |
| 1,9- | nonane dithiol | FL |
| (E)-2- | nonenoic acid | FL |
| 2- | nonenoic acid | FL |
| 9- | octadecenal | FL/FR |
| 3-oxo | octanoic acid glyceride | FL |
| 2- | octenal | FL/FR |
| 3- | octenoic acid | FL |
| (Z)-5- | octenoic acid | FL |
| | octyl heptanoate | FL/FR |
| | peanut dithiazine | FL |
| 2- | pentyl pyridine | FL |
| | perilla seed oil | FL/FR |
| 1- | phenethyl mercaptan | FL/FR |
| 1,3- | propane dithiol | FL |
| | propyl 2-methyl-3-furyl disulfide | FL |
| iso | propyl disulfide | FL |
| alpha- | terpinen-7-al | FL/FR |
| | terpinyl isobutyrate | FL/FR |
| 3- | thienyl mercaptan | FL |
| | thioacetic acid | FL |
| | undecanal propylene glycol acetal | FL/FR |
| | valeraldehyde diethyl acetal | FL |
| iso | valeraldehyde diethyl acetal | FL/FR |
| | valeraldehyde propylene glycol acetal | FL/FR |
|
| N-(2-(3,4- | dimethoxyphenyl)ethyl)-3,4-dimethoxycinnamic acid amide | FL |
| 3,7- | dimethyl-2,6-octadien-1-yl cyclopropyl carboxamide | FL |
| 4- | mercapto-2-pentanone 1% in acetoin | FL |
| 2- | methyl-1-methyl thio-2-butene | FL |
| | pyrrolidino-(1,2E)-4H-2,4-dimethyl-1,3,5-dithiazine | FL |
| 1-(2- | thienyl) butanone | FL |
| 10- | undecen-2-one | FL/FR |
| aldehydic |
| | acetyl nonyryl | FL/FR |
| alliaceous |
| 1,3- | butane dithiol | FL |
| | dimethyl trisulfide | FL/FR |
| 3- | tetrahydrothiophenone | FL |
| aromatic |
| laevo- | perillaldehyde | FL/FR |
| astringent |
| 2,3- | dimethyl quinoxaline | FL |
| bitter |
| | glyceryl tributyrate | FL |
| (E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
| burnt |
| | bacon dithiazine | FL |
| | rum ether | FL/FR |
| caramellic |
| | strawberry furanone acetate | FL/FR |
| cheesy |
| | hexanoic acid | FL/FR |
| chemical |
| 2,5- | dimethyl furan | FL |
| cocoa |
| | butyraldehyde | FL |
| coconut |
| delta- | octalactone | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| | furfuryl mercaptan | FL/FR |
| cooling |
| | manzanate (Givaudan) | FL/FR |
| corn |
| 2- | acetyl pyridine | FL/FR |
| creamy |
| | acetyl butyryl | FL/FR |
| | acetyl isobutyryl | FL/FR |
| 6- | amyl-alpha-pyrone | FL/FR |
| | octyl isobutyrate | FL/FR |
| delta- | undecalactone | FL/FR |
| gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| earthy |
| | difurfuryl sulfide | FL |
| 1,8- | octane dithiol | FL |
| eggy |
| iso | propyl mercaptan | FL |
| estery |
| | ethyl acetoacetate | FL/FR |
| ethereal |
| | benzyl laurate | FL/FR |
| fatty |
| | allyl octanoate | FL/FR |
| iso | amyl laurate | FL/FR |
| | butyl oleate | FL |
| | coconut absolute | FL/FR |
| (Z)- | dairy lactone | FL/FR |
| 2,4- | decadien-1-ol | FL/FR |
| 2,4- | decadienal | FL |
| (E,E)-2,4- | decadienal | FL |
| 2- | decenal | FL/FR |
| | dimethyl sulfoxide | FL |
| (E,E)-2,4- | dodecadienal | FL |
| | ethyl undecylenate | FL/FR |
| (E,E)-2,4- | heptadienal | FL |
| 2- | heptyl furan | FL/FR |
| (Z)-3- | hexen-1-yl benzoate | FL/FR |
| 4- | methyl nonanoic acid | FL/FR |
| 4- | methyl octanoic acid | FL/FR |
| 2,4- | nonadien-1-ol | FL/FR |
| (E,E)-2,4- | nonadienal | FL |
| 2,4- | nonadienal | FL |
| 2- | nonenal | FL/FR |
| 2,4- | octadien-1-ol | FL |
| (Z)-3- | octen-1-ol | FL/FR |
| (E)-2- | octenal | FL/FR |
| (E)-2- | octenoic acid | FL |
| (Z)- | oleic acid | FL/FR |
| | tetradecanal | FL/FR |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| floral |
| 3,7- | dimethyl-6-octenoic acid | FL/FR |
| | jasmin absolute (from pommade) | FL/FR |
| | orris rhizome concrete butter (iris pallida) | FL/FR |
| fruity |
| | allyl cyclohexyl propionate | FL/FR |
| | allyl hexanoate | FL/FR |
| | amyl hexanoate | FL/FR |
| gamma- | dodecalactone | FL/FR |
| | ethyl (E)-2-octenoate | FL |
| | ethyl hexanoate | FL/FR |
| | methyl 2-methyl butyrate | FL/FR |
| | octen-1-yl cyclopentanone | FL/FR |
| | strawberry glycidate 1 (aldehyde C-16 (so-called)) | FL/FR |
| | tropical trithiane | FL/FR |
| iso | valeraldehyde | FL/FR |
| green |
| 3- | decen-2-one | FL/FR |
| | dihydroxyacetophenone (mixed isomers) | FL |
| | dodecanal dimethyl acetal | FL/FR |
| (Z)-4- | heptenal | FL/FR |
| (E)-2- | heptenal | FL |
| (Z)-4- | heptenal diethyl acetal | FL/FR |
| | hexanal (aldehyde C-6) | FL/FR |
| (E)-3- | hexen-1-ol | FL/FR |
| (Z)-3- | hexen-1-yl pyruvate | FL/FR |
| (E)-2- | hexenal | FL/FR |
| 3-(5- | methyl-2-furyl) butanal | FL |
| | neryl butyrate | FL/FR |
| (E,Z)-3,6- | nonadien-1-ol | FL/FR |
| (E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| (E,Z)-2,6- | nonadienal | FL/FR |
| (E)-2- | nonenal | FL/FR |
| (E,E)-2,4- | octadienal | FL |
| 2,4- | octadienal | FL |
| | octanal diethyl acetal | FL/FR |
| (E)-2- | octen-1-yl acetate | FL/FR |
| 4- | penten-1-yl acetate | FL |
| herbal |
| | green hexanal | FL/FR |
| 5- | hydroxymethyl furfural | FL |
| | massoia bark oil | FL |
| ketonic |
| 3- | heptanone | FL/FR |
| lactonic |
| gamma- | octalactone | FL/FR |
| meaty |
| 4- | allyl-2,6-dimethoxyphenol | FL |
| | benzothiazole | FL/FR |
| 2,6- | dimethyl thiophenol | FL |
| 2,5- | dimethyl-3-furan thiol | FL |
| 1,1- | ethane dithiol 1% in ethanol 94.5% / ethyl acetate 4% | FL |
| 4- | furfuryl thio-2-pentanone | FL |
| | meaty dithiane | FL/FR |
| (R,S)-2- | mercapto-3-butanol | FL |
| 2- | mercaptomethyl pyrazine | FL |
| 2- | mercaptopropionic acid | FL/FR |
| 2- | methyl 3-(methyl thio) furan | FL |
| 12- | methyl tridecanal | FL |
| bis(2- | methyl-3-furyl) disulfide | FL |
| S-(2- | methyl-3-furyl) ethane thioate | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| | propyl 2-mercaptopropionate | FL |
| | pyrazinyl ethane thiol | FL |
| 2- | pyridinyl methane thiol | FL |
| | sulfurol | FL/FR |
| | sulfuryl acetate | FL/FR |
| | thialdine | FL |
| ortho- | thiocresol | FL |
| ortho- | thioguaiacol | FL |
| melon |
| | propyl 2,4-decadienoate | FL/FR |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| milky |
| gamma- | butyrolactone | FL/FR |
| dextro,laevo-3-( | methyl thio) butanone | FL |
| musk |
| dextro,laevo- | muscone | FL/FR |
| musty |
| 2- | ethoxythiazole | FL |
| | hazelnut pyrazine | FL/FR |
| nutty |
| 3,5- | diethyl-2-methyl pyrazine | FL |
| 2,5- | diethyl-3-methyl pyrazine | FL |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| | methyl benzoxole | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| | nutty thiazole | FL |
| oily |
| 2- | methyl hexanoic acid | FL/FR |
| | petal pyranone | FL/FR |
| onion |
| | furfuryl isopropyl sulfide | FL |
| | methionol | FL |
| popcorn |
| 2- | propionyl-2-thiazoline | FL |
| radish |
| 3-( | methyl thio) propyl mercaptoacetate | FL |
| ripe |
| (E)-4- | decenal | FL/FR |
| roasted |
| | hexyl mercaptan | FL |
| savory |
| N-(2,4- | dimethoxybenzyl)-N2-(2-(pyridin-2-yl)ethyl) oxalamide | FL |
| N-( | heptan-4-yl)benzo(D)(1,3)dioxole-5-carboxamide | FL |
| N1-(2- | methoxy-4-methyl benzyl)-N2-(2-(pyridin-2-yl)ethyl) oxalamide | FL |
| N1-(2- | methoxy-4-methyl benzyl)-N2-2(2-(5-methyl pyridin-2-yl)ethyl) oxalamide | FL |
| soapy |
| | decanoic acid | FL/FR |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| 1- | dodecanol | FL/FR |
| | octanoic acid | FL/FR |
| spicy |
| | allspice leaf oil | FL/FR |
| | cumin seed oil | FL/FR |
| 2- | octanol | FL/FR |
| sulfurous |
| 2,3- | butane dithiol | FL |
| S- | ethyl thioacetate | FL |
| | fish thiol | FL/FR |
| | methyl 2-methyl-3-furyl disulfide | FL |
| 3- | methyl-2-butane thiol | FL |
| 2- | naphthyl mercaptan | FL |
| | roasted butanol | FL |
| 2,4,6- | trithiaheptane 10% in triacetin | FL |
| sweet |
| | cyclohexyl acetic acid | FL/FR |
| vegetable |
| | tyramine | FL |
| waxy |
| | butyl undecylenate | FL/FR |
| | decanol | FL/FR |
| (E)-2- | decenal | FL/FR |
| 9- | decenoic acid | FL/FR |
| | ethyl undecanoate | FL/FR |
| | methyl 10-undecenoate | FL/FR |
| | methyl undecylenate | FL/FR |
| | myristic acid | FL/FR |
| | nonanol | FL/FR |
| (Z)-6- | nonen-1-ol | FL/FR |
| | octanol | FL/FR |
| delta- | tetradecalactone | FL/FR |
| | undecanal | FL/FR |
| | undecanoic acid | FL/FR |
| 2- | undecanone | FL/FR |
| woody |
| | perilla alcohol | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,6- | diercaptohexane | | 1,6- | dimercaptohexane | | | hexamethlyene dimercaptan | | | hexamethylene dimercaptan | | 1,6- | hexamethylenedithiol | | 1,6- | hexane dimercaptan | | | hexane-1,6-dithiol | | 1,6- | hexanedimercaptan | | 1, 6 | hexanedithiol | | 1,6- | hexanedithiol | | | USAF uctl-72 |
Articles:
| PubMed: | An immunosensor based on antibody binding fragments attached to gold nanoparticles for the detection of peptides derived from avian influenza hemagglutinin h5. |
| PubMed: | Macromol. Rapid commun. 15/2014. |
| PubMed: | Telechelic Poly(disulfide)s and Related Block Copolymer. |
| PubMed: | A regenerating self-assembled gold nanoparticle-containing electrochemical impedance sensor. |
| PubMed: | Multiwall carbon nanotube-ionic liquid electrode modified with gold nanoparticles as a base for preparation of a novel impedimetric immunosensor for low level detection of human serum albumin in biological fluids. |
| PubMed: | Enhanced magneto-optical properties of semiconductor EuS nanocrystals assisted by surface plasmon resonance of gold nanoparticles. |
| PubMed: | Enhanced wavelength modulation SPR biosensor based on gold nanorods for immunoglobulin detection. |
| PubMed: | Electrophoretic separation of gold nanoparticles according to bifunctional molecules-induced charge and size. |
| PubMed: | Thiol-ene chemistry guided preparation of thiolated polymeric nanocomposite for anodic stripping voltammetric analysis of Cd2+ and Pb2+. |
| PubMed: | Greatly extended storage stability of electrochemical DNA biosensors using ternary thiolated self-assembled monolayers. |
| PubMed: | A nanostructured piezoelectric immunosensor for detection of human cardiac troponin T. |
| PubMed: | Synthesis of phthalocyanine conjugates with gold nanoparticles and liposomes for photodynamic therapy. |
| PubMed: | Microfluidic biosensor for beta-amyloid(1-42) detection using cyclic voltammetry. |
| PubMed: | Synthesis and photophysical studies of phthalocyanine-gold nanoparticle conjugates. |
| PubMed: | Highly sensitive disposable nucleic acid biosensors for direct bioelectronic detection in raw biological samples. |
| PubMed: | Highly active engineered-enzyme oriented monolayers: formation, characterization and sensing applications. |
| PubMed: | Selective determination of 3,4-dihydroxyphenylacetic acid in the presence of ascorbic acid using 4-(dimethylamino)pyridine capped gold nanoparticles immobilized on gold electrode. |
| PubMed: | Electrochemical detection of DNA hybridization using a change in flexibility. |
| PubMed: | Covalent immobilization of cholesterol oxidase on self-assembled gold nanoparticles for highly sensitive amperometric detection of cholesterol in real samples. |
| PubMed: | Electrochemical real-time detection of L-histidine via self-cleavage of DNAzymes. |
| PubMed: | Electrochemical impedimetric immunosensor for insulin like growth factor-1 using specific monoclonal antibody-nanogold modified electrode. |
| PubMed: | Aptamer-based electrochemical approach to the detection of thrombin by modification of gold nanoparticles. |
| PubMed: | Immunosensor incorporating anti-His (C-term) IgG F(ab') fragments attached to gold nanorods for detection of His-tagged proteins in culture medium. |
| PubMed: | Electrochemical DNA biosensor fabrication with hollow gold nanospheres modified electrode and its enhancement in DNA immobilization and hybridization. |
| PubMed: | High-performance glucose amperometric biosensor based on magnetic polymeric bionanocomposites. |
| PubMed: | Architectures of bilayered gold nanoparticles on UV cross-linked poly(4-vinylpyridine) thin films. |
| PubMed: | Surface plasmon resonance biosensor based on water-soluble ZnO-Au nanocomposites. |
| PubMed: | Immobilization of specific monoclonal antibody on Au nanoparticles for hGH detection by electrochemical impedance spectroscopy. |
| PubMed: | Ultrasensitive electrochemical immunosensor for ochratoxin A using gold colloid-mediated hapten immobilization. |
| PubMed: | Sensitivity enhancement of SPR biosensor with silver mirror reaction on the Ag/Au film. |
| PubMed: | Reversible end-to-end assembly of gold nanorods using a disulfide-modified polypeptide. |
| PubMed: | Immobilization of enzymes through one-pot chemical preoxidation and electropolymerization of dithiols in enzyme-containing aqueous suspensions to develop biosensors with improved performance. |
| PubMed: | Measurements of stretch lengths of gold mono-atomic wires covered with 1,6-hexanedithiol in 0.1 M NaClO4 with an electrochemical scanning tunneling microscope. |
| PubMed: | Comparison of electrochemical immunosensors based on gold nano materials and immunoblot techniques for detection of histidine-tagged proteins in culture medium. |
| PubMed: | Photosystem I/molecular wire/metal nanoparticle bioconjugates for the photocatalytic production of H2. |
| PubMed: | Accurate determination of multiple sets of single molecular conductance of Au/1,6-hexanedithiol/Au break junctions by ultra-high vacuum-scanning tunneling microscope and analyses of individual current-separation curves. |
| PubMed: | Enzymatic synthesis of polythioester by the ring-opening polymerization of cyclic thioester. |
| PubMed: | Chemo-enzymatic preparation of copolymeric polythioesters containing branched-chain thioether groups. |
| PubMed: | Interpretation of stochastic events in single molecule conductance measurements. |
| PubMed: | Electrochemical impedance spectroscopy for study of amyloid beta-peptide interactions with (-) nicotine ditartrate and (-) cotinine. |
| PubMed: | Deposition of gold nanoparticles onto thiol-functionalized multiwalled carbon nanotubes. |
| PubMed: | Resistance changes due to thermal coalescence in colloidal au/organic linker molecule multilayer films. |
| PubMed: | Electrochemical and piezoelectric quartz crystal detection of antisperm antibody based on protected Au nanoparticles with a mixed monolayer for eliminating nonspecific binding. |
| PubMed: | In situ scanning tunneling microscopy of 1,6-hexanedithiol, 1,9-nonanedithiol, 1,2-benzenedithiol, and 1,3-benzenedithiol adsorbed on pt(111) electrodes. |
| PubMed: | In situ sensing of metal ion adsorption to a thiolated surface using surface plasmon resonance spectroscopy. |
| PubMed: | Characterization of surface-confined alpha-synuclein by surface plasmon resonance measurements. |
| PubMed: | Dithiol-mediated immobilization of CdS nanoparticles from reverse micellar system onto Zn-doped silica particles and their high photocatalytic activity. |
| PubMed: | Electrochemical behavior of Au colloidal electrode through layer-by-layer self-assembly. |
| PubMed: | 1,6-Hexanedithiol monolayer as a receptor for specific recognition of alkylmercury. |
| PubMed: | Organosulfur-functionalized Au, Pd, and Au-Pd nanoparticles on 1D silicon nanowire substrates: preparation and XAFS studies. |
| PubMed: | Investigations of step-growth thiol-ene polymerizations for novel dental restoratives. |
| PubMed: | Copolymeric polythioesters by lipase-catalyzed thioesterification and transthioesterification of alpha,omega-alkanedithiols. |
| PubMed: | Photoinduced plasticity in cross-linked polymers. |
| PubMed: | Direct observation of a cooperative mechanism in the adsorption of heavy metal ions to thiolated surface by in-situ surface plasmon resonance measurements. |
| PubMed: | Enzymatic synthesis of multi-component copolymers and their structural characterization. |
| PubMed: | Dithiol-mediated incorporation of CdS nanoparticles from reverse micellar system into Zn-doped SBA-15 mesoporous silica and their photocatalytic properties. |
| PubMed: | Piezoelectric quartz crystal impedance and electrochemical impedance study of HSA-diazepam interaction by nanogold-structured sensor. |
| PubMed: | Study of the immobilization of alcohol dehydrogenase on Au-colloid modified gold electrode by piezoelectric quartz crystal sensor, cyclic voltammetry, and electrochemical impedance techniques. |
| PubMed: | In-situ analysis of stepwise self-assembled 1,6-hexanedithiol multilayers by surface plasmon resonance measurements. |
| PubMed: | Sensitivity enhancement of DNA sensors by nanogold surface modification. |
| PubMed: | Gold Clustering at the Terminal Functions of Long-Chain Thiols and Amines. |
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