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Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 99.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.03000 to 1.03400 @ 20.00 °C.
|
| Pounds per Gallon - (est).: | 8.581 to 8.614
|
| Refractive Index: | 1.51800 to 1.52200 @ 20.00 °C.
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| Boiling Point: | 86.00 to 87.00 °C. @ 50.00 mm Hg
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| Boiling Point: | 69.00 to 70.00 °C. @ 28.00 mm Hg
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| Vapor Pressure: | 2.149000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 126.00 °F. TCC ( 52.22 °C. )
|
| logP (o/w): | 2.004 (est) |
| Soluble in: |
| | alcohol | | | fats | | | water, 1761 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: sulfurous |
| |
| | meaty beefy |
Odor Description: at 0.10 % in propylene glycol. | meaty beefy |
| |
| | sulfurous meaty alliaceous coffee |
Odor Description:
| Sulfureous, meaty and alliaceous with a coffee nuance Mosciano, Gerard P&F 22, No. 3, 47, (1997) |
| |
| |
| Flavor Type: sulfurous |
| |
| | sulfurous fatty roasted beefy eggy pork |
Taste Description:
| Sulfureous, fatty and roast beef-Iike with egg, salami and pork nuances Mosciano, Gerard P&F 22, No. 3, 47, (1997) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
| Ambles Nature et Chimie |
| 2.3-BUTANEDITHIOL
|
| Anhui Suzhou Jinli Aromatic Chemicals |
| 2,3-Butanedithiol
Odor: roast beef |
| Beijing Lys Chemicals |
| 2,3-Butanedithiol
|
| BOC Sciences |
| For experimental / research use only. |
| 2,3-Butanedithiol
|
| Carbosynth |
| For experimental / research use only. |
| 2,3-Butanedithiol
|
| DeLong Chemicals America |
| 2,3-Butanedithiol, Kosher
|
| Endeavour Specialty Chemicals |
| 2,3-Butanedithiol
|
| Speciality Chemical Product Groups |
| Fleurchem |
| 2,3-butanedithiol
|
| H. Interdonati, Inc. |
| 2,3-Butanedithiol Kosher
|
| Featured Products |
| Jiangyin Healthway |
| 2,3-Butanedithiol
|
| New functional food ingredients |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| 2,3-Butanedithiol, Kosherk
|
| M&U International |
| 2,3-BUTANEDITHIOL, Kosher
|
| OQEMA |
| 2,3-Butanedithiol
|
| Penta International |
| 2,3-BUTANEDITHIOL
|
| R C Treatt & Co Ltd |
| 2,3-Butanedithiol
Kosher |
| Robinson Brothers |
| 2,3-Butanedithiol F&F
|
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 2,3-Butanedithiol
|
| Sigma-Aldrich |
| 2,3-Butanedithiol, ≥99%, FG
|
| Certified Food Grade Products |
| Sunaux International |
| 2,3-Butanedithiol
|
| Synerzine |
| 2,3-Butanedithiol
|
| TCI AMERICA |
| For experimental / research use only. |
| 2,3-Butanedithiol >98.0%(GC)
|
| Tengzhou Jitian Aroma Chemiclal |
| 2,3-Butane Dithiol
|
| Tengzhou Xiang Yuan Aroma Chemicals |
| 2,3-Butanedithiol
|
| Tianjin Danjun International |
| 2,3-Butanedithiol
|
| United International |
| 2,3-Butanedithiol
|
| WholeChem |
| 2,3-Butanedithiol
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 10 - Flammable. R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 20/21 - When using do not eat, drink or smoke. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | flavoring agents |
| Recommendation for 2,3-butane dithiol usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.049 (μg/capita/day) |
| NOEL (No Observed Effect Level): | 0.7 (mg/kg bw per day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 10 |
| Click here to view publication 10 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 0.20000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | - |
| fruit ices: | - | - |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | 0.20000 |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 0.20000 |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | 0.20000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 4532-64-3 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 548353 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 3336 |
| WGK Germany: | 3 |
| | butane-2,3-dithiol |
| Chemidplus: | 0004532643 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| alliaceous |
| | methyl furfuryl disulfide | FL/FR |
| chocolate |
| 2,6- | dimethyl pyrazine | FL/FR |
| 2,5- | dimethyl pyrazine | FL/FR |
| green |
| (E,Z)-2,6- | nonadienal | FL/FR |
| | sulfurol | FL/FR |
| | sulfuryl acetate | FL/FR |
| nutty |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| 2,4,5- | trimethyl oxazole | FL/FR |
| | ethyl 2-mercaptopropionate | FL/FR |
| | fish thiol | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | benzyl methyl sulfide | FL |
| 2,5- | dimethyl-3-thiofuroyl furan | FL |
| 2- | formyl pyrrole | FL |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| 2- | methyl-1-butane thiol | FL |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| 3-((2- | methyl-3-furyl)thio)-4-heptanone | FL |
| 1,9- | nonane dithiol | FL |
| iso | propyl disulfide | FL |
|
| 3,7- | dimethyl-2,6-octadien-1-yl cyclopropyl carboxamide | FL |
| 2,4- | dimethyl-3-oxazoline | FL |
| 2- | methyl-1-methyl thio-2-butene | FL |
| 1-(2- | thienyl) butanone | FL |
| alliaceous |
| 1,3- | butane dithiol | FL |
| burnt |
| 1,6- | hexane dithiol | FL |
| 2,4,5- | trimethyl oxazole | FL/FR |
| chemical |
| 2,5- | dimethyl furan | FL |
| coffee |
| 2,4- | dimethyl thiazole | FL |
| | methyl furfuryl disulfide | FL/FR |
| earthy |
| 1,8- | octane dithiol | FL |
| eggy |
| iso | propyl mercaptan | FL |
| green |
| (E,Z)-2,6- | nonadienal | FL/FR |
| meaty |
| 2,6- | dimethyl pyrazine | FL/FR |
| 2,6- | dimethyl thiophenol | FL |
| 2,5- | dimethyl-3-furan thiol | FL |
| 1,1- | ethane dithiol 1% in ethanol 94.5% / ethyl acetate 4% | FL |
| | furfuryl 2-methyl-3-furyl disulfide | FL |
| 3- | mercapto-2-butanone | FL |
| 2- | mercaptopropionic acid | FL/FR |
| 2- | methyl 3-(methyl thio) furan | FL |
| bis(2- | methyl-3-furyl) disulfide | FL |
| S-(2- | methyl-3-furyl) ethane thioate | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| | propyl 2-mercaptopropionate | FL |
| | pyrazinyl ethane thiol | FL |
| 2- | pyridinyl methane thiol | FL |
| | sulfurol | FL/FR |
| | sulfuryl acetate | FL/FR |
| | thialdine | FL |
| ortho- | thiocresol | FL |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| musty |
| 2,5- | dimethyl pyrazine | FL/FR |
| nutty |
| | nutty thiazole | FL |
| onion |
| | ethyl 2-mercaptopropionate | FL/FR |
| roasted |
| | hexyl mercaptan | FL |
| sulfurous |
| | fish thiol | FL/FR |
| | methyl 2-methyl-3-furyl disulfide | FL |
| 3- | methyl-2-butane thiol | FL |
| | roasted butanol | FL |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | butane-2,3-dithiol | | 2,3- | butanedithiol | | 2,3- | dimercaptobutane | | | dithione (IFF) | | | dithione 865 (IFF) |
Articles:
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