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Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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| Odor Type: alliaceous |
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| Odor Strength: | very high , recommend smelling in a 0.01 % solution or less |
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| Substantivity: | 9 hour(s) at 100.00 % |
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| | ripe onion gassy meaty sulfurous |
Odor Description: at 0.10 % in propylene glycol. | strong ripe onion gassy meaty sulfurous Luebke, William tgsc, 1993) |
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| | onion sharp pungent meaty sulfurous brothy chicken |
Odor Description: at 0.01 % in ethyl alcohol. | Onion, sharp and pungent, meaty sulfurous, brothy chicken and poultry-like Mosciano, Gerard P&F 24, No. 6, 10, (1999) |
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| Flavor Type: eggy |
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| | eggy egg yolk sulfurous chicken leek onion |
Taste Description: at 50.00 - 500.00 ppm. | Soft-boiled egg yolk, hydrogen sulfide, rich mouth feel, strong poultry, leek and onion-like Mosciano, Gerard P&F 24, No. 6, 10, (1999) |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 11 - Highly flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 33 - Take precautionary measures against static discharge. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
inhalation-mouse LC50 130000 mg/m3/1H BEHAVIORAL: REGIDITY
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) National Technical Information Service. Vol. OTS0571940
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Safety in Use Information:
| Category: | flavoring agents |
| Recommendation for isopropyl mercaptan usage levels up to: | | | not for fragrance use.
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| Maximised Survey-derived Daily Intakes (MSDI-EU): | ND (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 18 |
| Click here to view publication 18 |
| | average usual ppm | average maximum ppm |
| baked goods: | 0.10000 | 5.00000 |
| beverages(nonalcoholic): | 0.10000 | 5.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | 0.10000 | 5.00000 |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 0.10000 | 5.00000 |
| fruit ices: | - | - |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | 0.10000 | 5.00000 |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | 0.10000 | 5.00000 |
| milk products: | 0.10000 | 5.00000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | 20.00000 | 200.00000 |
| snack foods: | - | - |
| soft candy: | 0.10000 | 5.00000 |
| soups: | 0.10000 | 5.00000 |
| sugar substitutes: | - | - |
| sweet sauces: | 0.10000 | 5.00000 |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on the safety and efficacy of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups (chemical group 20) when used as flavourings for all animal species View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 75-33-2 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6364 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 2402 |
| WGK Germany: | 3 |
| | propane-2-thiol |
| Chemidplus: | 0000075332 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | TZ7302000 for cas# 75-33-2 |
References:
Other Information:
Potential Blenders and core components note
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| For Odor |
| alliaceous |
| | dimethyl trisulfide | FL/FR |
| | dipropyl disulfide | FL/FR |
| | ferula assa-foetida gum oil | FL/FR |
| | methyl furfuryl disulfide | FL/FR |
| | propyl mercaptan | FL/FR |
| citrus |
| | grapefruit mercaptan | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| ethereal |
| 2- | methyl-1-butanol | FL/FR |
| meaty |
| | meaty dithiane | FL/FR |
| 4- | methyl nonanoic acid | FL/FR |
| | dimethyl disulfide | FL/FR |
| | dimethyl sulfide | FL/FR |
| | ethyl 2-mercaptopropionate | FL/FR |
| | ferula assa-foetida absolute | FL/FR |
| | fish thiol | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| | methyl 3-(methyl thio) propionate | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| 3-( | methyl thio) hexanol | FL/FR |
| | onion oil | FL/FR |
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| For Flavor |
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| No flavor group found for these |
| | allyl methyl disulfide | FL |
| | allyl methyl trisulfide | FL |
| | allyl propyl disulfide | FL |
| | allyl propyl sulfide | FL |
| | allyl propyl trisulfide | FL |
| iso | amyl mercaptan | FL |
| | benzyl methyl sulfide | FL |
| | diethyl trisulfide | FL |
| (Z+E)-2,5- | dimethyl-3-tetrahydrofuran thiol | FL |
| (Z+E)-2,5- | dimethyl-3-thioacetoxytetrahydrofuran | FL |
| | dipropyl sulfide | FL |
| | ethyl methyl trisulfide | FL |
| | ethyl propyl disulfide | FL |
| | ethyl propyl trisulfide | FL |
| | heptyl mercaptan | FL |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| 2-( | methyl thio) methyl-2-butenal | FL |
| 2- | methyl-1-butane thiol | FL |
| 1,9- | nonane dithiol | FL |
| | propenyl propyl disulfide | FL |
| iso | propyl disulfide | FL |
| 2,3,5- | trithiahexane | FL |
| alliaceous |
| | allyl disulfide | FL |
| | allyl mercaptan | FL |
| | allyl thiopropionate | FL |
| | benzyl mercaptan | FL |
| 1,3- | butane dithiol | FL |
| | cyclopentyl mercaptan | FL |
| | dicyclohexyl disulfide | FL |
| | diethyl disulfide | FL |
| | dimethyl trisulfide | FL/FR |
| | dipropyl disulfide | FL/FR |
| | dipropyl trisulfide | FL |
| | ferula assa-foetida gum oil | FL/FR |
| | leek oil | FL |
| 3- | mercapto-2-methyl pentanol | FL |
| 3- | mercapto-2-pentanone | FL |
| | methyl 3-mercaptobutanoate | FL |
| 2- | methyl thioacetaldehyde | FL |
| | propyl mercaptan | FL/FR |
| cabbage |
| | methyl 2-thiofuroate | FL |
| citrus |
| | grapefruit mercaptan | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| | methyl furfuryl disulfide | FL/FR |
| corn chip |
| 2- | acetyl-2-thiazoline | FL |
| earthy |
| 1,8- | octane dithiol | FL |
| ethereal |
| 2- | methyl-1-butanol | FL/FR |
| fatty |
| 4- | methyl nonanoic acid | FL/FR |
| 2,4- | octadien-1-ol | FL |
| garlic |
| | allyl methyl sulfide | FL |
| | garlic oleoresin | FL |
| meaty |
| 2,6- | dimethyl thiophenol | FL |
| 2,5- | dimethyl-3-furan thiol | FL |
| | furfuryl 2-methyl-3-furyl disulfide | FL |
| | meaty dithiane | FL/FR |
| 3- | mercapto-2-butanone | FL |
| (R,S)-2- | mercapto-3-butanol | FL |
| 2- | mercaptopropionic acid | FL/FR |
| 2- | methyl 3-(methyl thio) furan | FL |
| bis(2- | methyl-3-furyl) disulfide | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| | pyrazinyl ethane thiol | FL |
| ortho- | thiocresol | FL |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| 3-( | methyl thio) hexanol | FL/FR |
| musty |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| onion |
| | ethyl 2-mercaptopropionate | FL/FR |
| | methionol | FL |
| | methyl propyl disulfide | FL |
| | methyl propyl trisulfide | FL |
| | propyl thioacetate | FL |
| roasted |
| | ethyl 3-(furfuryl thio) propionate | FL |
| seafood |
| 1,4- | dithiane | FL |
| sulfurous |
| | allyl sulfide | FL |
| 2,3- | butane dithiol | FL |
| | butyl mercaptan | FL |
| | diallyl polysulfides | FL |
| | diallyl tetrasulfide | FL |
| | diallyl trisulfide | FL |
| | dimethyl disulfide | FL/FR |
| | dimethyl sulfide | FL/FR |
| S- | ethyl thioacetate | FL |
| | ferula assa-foetida absolute | FL/FR |
| | fish thiol | FL/FR |
| | furfuryl methyl sulfide | FL |
| | furfuryl thiopropionate | FL |
| 3- | mercapto-2-methyl pentanal | FL |
| | methyl 2-(methyl thio) butyrate | FL |
| | methyl 2-methyl-3-furyl disulfide | FL |
| | methyl thiomethyl butyrate | FL |
| 2- | methyl thiophene | FL |
| | onion oil | FL/FR |
| | onion oleoresin | FL |
| vegetable |
| | methyl 3-(methyl thio) propionate | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2- | mercaptopropane | | 1- | methyl ethane thiol | | 1- | methylethanethiol | | 2- | propane thiol | | iso | propane thiol | | | propane-2-thiol | | 2- | propanethiol | | iso | propanethiol | | 2- | propyl mercaptan | | iso | propyl thiol | | 2- | propylmercaptan | | iso | propylmercaptan | | iso | propylthiol |
Articles:
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