|
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | yellow clear liquid (est) |
| Assay: | 96.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.36600 to 1.37800 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 11.366 to 11.466
|
| Refractive Index: | 1.67100 to 1.69300 @ 20.00 °C.
|
| Boiling Point: | 142.00 to 147.00 °C. @ 0.80 mm Hg
|
| Boiling Point: | 396.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 0.000003 mmHg @ 25.00 °C. (est) |
| Flash Point: | 147.00 °F. TCC ( 63.89 °C. )
|
| logP (o/w): | 6.708 (est) |
| Soluble in: |
| | alcohol | | | water, 4.06 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: sulfurous |
| |
| | sulfurous meaty |
Odor Description: at 0.10 % in propylene glycol. | sulfury meaty |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
gavage-mouse LD50 [sex: M,F] 220 mg/kg (Oser, 1970c)
gavage-mouse LD50 [sex: M,F] 220 mg/kg (Moran et al., 1980)
oral-mouse LD50 220 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | flavoring agents |
| Recommendation for 2-methyl-3-furyl tetrasulfide usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.97 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.70 (μg/capita/day) |
| Structure Class: | III |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 5 |
| Click here to view publication 5 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 0.10000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | 0.10000 |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | 0.10000 |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | - |
| fruit ices: | - | - |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | 0.10000 |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 0.10000 |
| milk products: | - | 0.10000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | 0.10000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009) View page or View pdf |
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 65, Revision 1 (FGE.65Rev1): Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated by EFSA in FGE.13Rev2 (2011) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 24832089 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | 2-methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan |
| Chemidplus: | 0028588763 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| coffee |
| coffee |
| | coffee difuran | FL/FR |
| floral |
| 6,8- | dimethyl-2-nonanol | FR |
| meaty |
| | meaty dithiane | FL/FR |
| 4- | methyl nonanoic acid | FL/FR |
| | fish thiol | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | benzyl methyl sulfide | FL |
| | ethyl 4-(acetyl thio) butyrate | FL |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| 1,9- | nonane dithiol | FL |
| 1,3- | propane dithiol | FL |
| iso | propyl disulfide | FL |
| alliaceous |
| 1,3- | butane dithiol | FL |
| coffee |
| | coffee difuran | FL/FR |
| corn chip |
| 2- | acetyl-2-thiazoline | FL |
| earthy |
| | difurfuryl sulfide | FL |
| 1,8- | octane dithiol | FL |
| eggy |
| iso | propyl mercaptan | FL |
| fatty |
| 4- | methyl nonanoic acid | FL/FR |
| 2,4- | octadien-1-ol | FL |
| green |
| 4- | penten-1-yl acetate | FL |
| meaty |
| 2,6- | dimethyl thiophenol | FL |
| 2,5- | dimethyl-3-furan thiol | FL |
| | meaty dithiane | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| S-(2- | methyl-3-furyl) ethane thioate | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| | pyrazinyl ethane thiol | FL |
| ortho- | thiocresol | FL |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| nutty |
| | nutty thiazole | FL |
| roasted |
| | hexyl mercaptan | FL |
| sulfurous |
| 2,3- | butane dithiol | FL |
| | fish thiol | FL/FR |
| | methyl 2-methyl-3-furyl disulfide | FL |
| | roasted butanol | FL |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | furan, 3,3'-(1,4-tetrasulfanediyl)bis[2-methyl- | | 2- | methyl-3-[(2-methyl-3-furyl)disulfanyldisulfanyl]furan | | bis(2- | methyl-3-furyl) tetrasulfide | | bis(2- | methyl-3-furyl)tetrasulfide | | 3,3'-(1,4- | tetrasulfanediyl)bis[2-methylfuran] | | 3,3- | tetrathiobis(2-methyl furan) | | 3,3'- | tetrathiobis[2-methylfuran] |
Articles:
|