Articles:
| US Patents: | 3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines |
3,5-diethyl-2-methylpyrazine
Notes:
Found in potato, chicken, beef and pork, tea, coffee, galbanum oil and other foods. Flavouring agent
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Myrazine LLC EU Natural Ingredients from Fermentation All the materials are sourced from fermentation. Myrazine LLC,formerly known as Cheng Smith LLC, and Abioco, started its search for Natural materials in 2000, when we started to import natural alcohols from China. China's liquor fermentation technology is as old as the country. Chinese liquor is? unique, because it is fermented from grains, such as rice, wheat, sorghum, and barleys. With bacteria or microorganism present in the fermentaiton, Chinese liquor is rich in flavours. It is reported that there are over 100 flavour materials in the liquor fermentation broth. During the production, the "good" liquor is distilled out, and the "bad" alcohols are dumped as "wastes" before 1980s. Fusel oil is regarded and dumped as the "bad" one during the production. Today, every single ton of the liquor fermentation "wastes" --- fusel oil, has been physically distilled. Alcohols from these distillations are methyl alcohol, ethanol, propanol, butanol, iso-butanol, iso-amyl alcohol, etc. Most of the alcohols are used by the flavour and fragrances industry as raw materials, which eventually go into the beverages, food, and some daily products. According to the US and EU regulations about natural ingredients, materials from fermentation are regarded as "natural". Email: Info Email: Sales Voice: +1.623 565 7047 Product(s): Pyrazine, 3,5-diethyl-2-methyl-
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 04-15620 3,5-DIETHYL-2-METHYL PYRAZINE
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| CAS Number: | 18138-05-1 |  3D/inchi
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| FDA UNII: | 7JG7NP41LF | |
| Nikkaji Web: | J82.718E | |
| CoE Number: | 11305 | |
| XlogP3-AA: | 1.80 (est) | |
| Molecular Weight: | 150.22458000 | |
| Formula: | C9 H14 N2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 779 3,5-diethyl-2-methylpyrazine |
| DG SANTE Food Flavourings: | 14.095 3,5-diethyl-2-methylpyrazine |
| FEMA Number: | 3916 3,5-diethyl-2-methylpyrazine |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 18138-05-1 ; 3,5-DIETHYL-2-METHYLPYRAZINE |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 97.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.94400 to 0.95400 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 7.855 to 7.938 |
| Refractive Index: | 1.49200 to 1.50200 @ 20.00 °C. |
| Boiling Point: | 95.00 °C. @ 14.00 mm Hg |
| Boiling Point: | 205.00 to 206.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.353000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 170.00 °F. TCC ( 76.67 °C. ) |
| logP (o/w): | 1.966 (est) |
| Soluble in: | |
| alcohol | |
| propylene glycol | |
| water, slightly | |
| water, 488.9 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: nutty | |
| nutty meaty vegetable | |
| Odor Description: at 0.10 % in dipropylene glycol. | nutty meaty vegetable |
| Flavor Type: nutty | |
| green nutty | |
| Taste Description: | green nutty |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Myrazine |
| Pyrazine, 3,5-diethyl-2-methyl-
Odor: nutty meaty vegetable |
| Parchem |
| 3,5-diethyl-2-methyl pyrazine |
| Penta International |
| 3,5-DIETHYL-2-METHYL PYRAZINE |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for 3,5-diethyl-2-methyl pyrazine usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.01 (μg/capita/day) | ||
| Structure Class: | II | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 19 | |||
| Click here to view publication 19 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 1.00000 | 2.00000 | |
| beverages(nonalcoholic): | 0.50000 | 1.00000 | |
| beverages(alcoholic): | 0.10000 | 0.50000 | |
| breakfast cereal: | 1.00000 | 2.00000 | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | 0.50000 | 1.00000 | |
| fruit ices: | - | - | |
| gelatins / puddings: | 0.50000 | 1.00000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | - | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | 0.50000 | 1.00000 | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | 1.00000 | 2.00000 | |
| soups: | 0.10000 | 0.50000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf | |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf | |
| Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 28906 |
| National Institute of Allergy and Infectious Diseases: | Data |
| 3,5-diethyl-2-methylpyrazine | |
| Chemidplus: | 0018138051 |
References:
| 3,5-diethyl-2-methylpyrazine | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 28906 |
| Pubchem (sid): | 134993060 |
| Flavornet: | 18138-05-1 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB32946 |
| FooDB: | FDB010931 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| green | FL | |
| nut | FL | |
| vegetable | FL |
Occurrence (nature, food, other): note
| beef Search PMC Picture | |
| coffee Search PMC Picture | |
| galbanum oil Search Trop Picture | |
| pepper red pepper seed oil Search PMC Picture | |
| pork Search PMC Picture | |
| potato Search Trop Picture | |
| tea Search Trop Picture | |
| wine Search Picture |
Synonyms:
| diethyl methyl pyrazine | |
| 3,5- | diethyl-2-methylpyrazine |
| 2,6- | diethyl-3-methyl pyrazine |
| 2,6- | diethyl-3-methylpyrazine |
| 2- | methyl-3,5-diethyl-1,4-diazine |
| 2- | methyl-3,5-diethylpyrazine |
| pyrazine, 3,5-diethyl-2-methyl- |