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Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.06400 to 1.07100 @ 20.00 °C.
|
| Pounds per Gallon - (est).: | 8.864 to 8.922
|
| Refractive Index: | 1.50600 to 1.51400 @ 20.00 °C.
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| Boiling Point: | 164.22 °C. @ 760.00 mm Hg (est)
|
| Vapor Pressure: | 2.606000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 100.00 °F. TCC ( 37.78 °C. )
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| logP (o/w): | 2.324 (est) |
| Soluble in: |
| | alcohol | | | water, 670.5 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: sulfurous |
| |
| | beefy cheesy coffee minty spicy |
Odor Description: at 10.00 % in triacetin. | beefy cheese coffee minty spicy |
| |
| | spicy pungent alliaceous sulfurous dry meaty brothy mustard coffee |
Odor Description: at 1.00 % in propylene glycol. | Spicy, pungent alliaceous, sulfurous drying to a meaty brothy aroma with mustard and coffee nuances Mosciano, Gerard P&F 26, No. 5, 68, (2001) |
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| Flavor Type: meaty |
| |
| | meaty spicy solvent coffee nutty cheesy |
Taste Description: at 0.10 - 0.40 ppm. | Mild meaty, spicy, slightly solvent like with coffee, nutty and cheesy nuances Mosciano, Gerard P&F 26, No. 5, 68, (2001) |
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| Odor and/or flavor descriptions from others (if found). |
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| Sigma-Aldrich |
| 2-Methyl-3-methylthiofuran, ≥98%, FG |
| Odor Description: | cheese; nutty; sulfurous; meaty; spicy; coffee |
| |
| Taytonn ASCC |
| Methylmethylthiofuran (10% IN Tac) |
| Odor Description: | Cheese, Coffee, Meaty, Minty, Spicy |
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| |
Cosmetic Information:
Suppliers:
| Ambles Nature et Chimie |
| 2-METHYL-3-METHYLTHIO FURAN
|
| Anhui Suzhou Jinli Aromatic Chemicals |
| 2-Methyl-3-methylthio furan
Odor: meat, nut |
| Beijing Lys Chemicals |
| 2-Methyl-3-(methylthio)furan
|
| BOC Sciences |
| For experimental / research use only. |
| 2-Methyl-3-methylthiofuran
|
| Carbosynth |
| For experimental / research use only. |
| 2-Methyl-3-(methylthio)furan
|
| Charkit Chemical |
| METHYL-3-(METHYLTHIO) FURAN,2- FEMA 3949
|
| DeLong Chemicals America |
| 2-Methyl-3-(methylthio)furan, Kosher
|
| Endeavour Specialty Chemicals |
| 2-Methyl-3-(methylthio)furan 99% F&F
|
| Speciality Chemical Product Groups |
| H. Interdonati, Inc. |
| 2-Methyl-3-(methylthio)furan Kosher
|
| Featured Products |
| Jiangyin Healthway |
| 2-Methyl-3-methylthio furan
|
| New functional food ingredients |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| 2-Methyl-3-methylthio furan, Kosherk
|
| M&U International |
| 2-METHYL-3-METHYLTHIO FURAN, Kosher
|
| Penta International |
| 2-METHYL-3-METHYLTHIOFURAN
|
| R C Treatt & Co Ltd |
| 2-Methyl-3-methylthiofuran
Halal, Kosher |
| Robinson Brothers |
| 2-Methyl-3-(methylthio)furan F&F
|
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 2-Methyl-3-(methylthio)furan
|
| Sigma-Aldrich |
| 2-Methyl-3-methylthiofuran, ≥98%, FG
Odor: cheese; nutty; sulfurous; meaty; spicy; coffee |
| Certified Food Grade Products |
| Sunaux International |
| 2-Methyl-3-methylthio Furan
|
| Synerzine |
| 2-METHYL-3-METHYLTHIOFURAN
|
| Taytonn ASCC |
| Methylmethylthiofuran (10% IN Tac)
Odor: Cheese, Coffee, Meaty, Minty, Spicy |
| TCI AMERICA |
| For experimental / research use only. |
| 2-Methyl-3-(methylthio)furan >98.0%(GC)
|
| Tengzhou Jitian Aroma Chemiclal |
| 2-Methyl-3-methylthio furan
|
| Tengzhou Xiang Yuan Aroma Chemicals |
| 2-Methy-3-Methylthio Furan
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| Tianjin Danjun International |
| 2-Methyl-3-(methylthio)furan
|
| United International |
| 2-Methyl-3-Methylthio furan
|
| WholeChem |
| 2-Methyl-3-methylthio furan
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
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| Dermal Toxicity: |
|
Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | flavoring agents |
| Recommendation for 2-methyl 3-(methyl thio) furan usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 1.20 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.10 (μg/capita/day) |
| NOEL (No Observed Effect Level): | 1.30 (mg/kg bw per day) |
| Structure Class: | II |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 19 |
| Click here to view publication 19 |
| | average usual ppm | average maximum ppm |
| baked goods: | 0.02000 | 0.20000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | 0.00500 | 0.05000 |
| chewing gum: | - | - |
| condiments / relishes: | 0.00100 | 0.01000 |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | 0.03000 | 0.30000 |
| frozen dairy: | - | - |
| fruit ices: | - | - |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | 0.03000 | 0.30000 |
| hard candy: | - | - |
| imitation dairy: | 0.00500 | 0.05000 |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | 0.05000 | 0.50000 |
| milk products: | 0.00500 | 0.05000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | 0.05000 | 0.50000 |
| processed fruits: | - | - |
| processed vegetables: | 0.00300 | 0.03000 |
| reconstituted vegetables: | 0.00300 | 0.03000 |
| seasonings / flavors: | 0.05000 | 0.50000 |
| snack foods: | 0.03000 | 0.30000 |
| soft candy: | - | - |
| soups: | 0.03000 | 0.30000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009) View page or View pdf |
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 65, Revision 1 (FGE.65Rev1): Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated by EFSA in FGE.13Rev2 (2011) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 526618 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 1993 |
| WGK Germany: | 3 |
| | 2-methyl-3-methylsulfanylfuran |
| Chemidplus: | 0063012975 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| alliaceous |
| | dimethyl trisulfide | FL/FR |
| | dipropyl disulfide | FL/FR |
| | ferula assa-foetida gum oil | FL/FR |
| | rum ether | FL/FR |
| caramellic |
| | fenugreek absolute | FL/FR |
| | cocoa hexenal | FL/FR |
| 2,6- | dimethyl pyrazine | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| | meaty dithiane | FL/FR |
| 4- | methyl nonanoic acid | FL/FR |
| | sulfuryl acetate | FL/FR |
| | hazelnut pyrazine | FL/FR |
| | menthofuran | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2,6- | lutidine | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| | ethyl 2-mercaptopropionate | FL/FR |
| | ethyl 3-mercaptopropionate | FL/FR |
| | fish thiol | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| | methyl mercaptan | FL/FR |
| | onion oil | FL/FR |
| 1- | phenethyl mercaptan | FL/FR |
| vegetable |
| | tetrahydrofurfuryl alcohol | FL/FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| 4- | acetyl-2-methyl pyrimidine | FL |
| | allyl methyl disulfide | FL |
| | allyl methyl trisulfide | FL |
| | allyl propyl trisulfide | FL |
| gamma- | aminobutyric acid | FL |
| | amyl mercaptan | FL |
| 2-(2- | butyl)-4,5-dimethyl-3-thiazoline | FL |
| | cyclopropyl (E,Z)-2,6-nonadienamide | FL |
| 2,5- | diethyl thiazole | FL |
| | dimethyl tetrasulfide | FL |
| 2,6- | dimethyl-3-((2-methyl-3-furyl)thio)-4-heptanone | FL |
| bis(2,5- | dimethyl-3-furyl) disulfide | FL |
| 2,5- | dimethyl-3-thiofuroyl furan | FL |
| | ethyl (E,Z)-2,6-nonadienamide | FL |
| S- | ethyl 2-acetyl aminoethane thioate | FL |
| | ethyl 3-mercaptopropionate | FL/FR |
| | ethyl 4-(acetyl thio) butyrate | FL |
| | ethyl propyl trisulfide | FL |
| (Z+E)-5- | ethyl-4-methyl-2-(2-butyl) thiazoline | FL |
| (Z+E)-5- | ethyl-4-methyl-2-(2-methyl propyl) thiazoline | FL |
| | furfuryl propyl disulfide | FL |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| | methyl dihydrofuran thiol | FL |
| 2- | methyl thiazolidine | FL |
| 2-( | methyl thio) ethanol | FL |
| S- | methyl thiopropionate | FL |
| 2- | methyl-1-butane thiol | FL |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| 2- | methyl-3-furyl tetrasulfide | FL |
| 3-((2- | methyl-3-furyl)thio)-4-heptanone | FL |
| 4-((2- | methyl-3-furyl)thio)-5-nonanone | FL |
| 1,9- | nonane dithiol | FL |
| | peanut dithiazine | FL |
| 1- | phenethyl mercaptan | FL/FR |
| 1,3- | propane dithiol | FL |
| iso | propyl disulfide | FL |
| | thiazole | FL |
| 3- | thienyl mercaptan | FL |
| | thiophene | FL |
|
| N-(2-(3,4- | dimethoxyphenyl)ethyl)-3,4-dimethoxycinnamic acid amide | FL |
| 3,7- | dimethyl-2,6-octadien-1-yl cyclopropyl carboxamide | FL |
| 4- | mercapto-2-pentanone 1% in acetoin | FL |
| 2- | methyl-1-methyl thio-2-butene | FL |
| | pyrrolidino-(1,2E)-4H-2,4-dimethyl-1,3,5-dithiazine | FL |
| 1-(2- | thienyl) butanone | FL |
| alliaceous |
| | allyl mercaptan | FL |
| 1,3- | butane dithiol | FL |
| | dimethyl trisulfide | FL/FR |
| | dipropyl disulfide | FL/FR |
| | dipropyl trisulfide | FL |
| | ferula assa-foetida gum oil | FL/FR |
| | leek oil | FL |
| 3- | mercapto-2-pentanone | FL |
| | shallot oil | FL |
| 3- | tetrahydrothiophenone | FL |
| | truffle sulfide | FL |
| beefy |
| | beef jerky flavor | FL |
| burnt |
| | bacon dithiazine | FL |
| 1,6- | hexane dithiol | FL |
| | rum ether | FL/FR |
| caramellic |
| | fenugreek absolute | FL/FR |
| | fenugreek distillates | FL |
| chemical |
| 2,5- | dimethyl furan | FL |
| cocoa |
| | butyraldehyde | FL |
| | cocoa hexenal | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| 2,4- | dimethyl thiazole | FL |
| earthy |
| | difurfuryl sulfide | FL |
| 1,8- | octane dithiol | FL |
| eggy |
| iso | propyl mercaptan | FL |
| fatty |
| 4- | methyl nonanoic acid | FL/FR |
| fruity |
| | furfuryl propionate | FL |
| garlic |
| | allyl methyl sulfide | FL |
| meaty |
| 4- | allyl-2,6-dimethoxyphenol | FL |
| BBQ | beef flavor | FL |
| 2,6- | dimethyl pyrazine | FL/FR |
| 2,6- | dimethyl thiophenol | FL |
| 2,5- | dimethyl-3-furan thiol | FL |
| 1,1- | ethane dithiol 1% in ethanol 94.5% / ethyl acetate 4% | FL |
| | furfuryl 2-methyl-3-furyl disulfide | FL |
| 4- | furfuryl thio-2-pentanone | FL |
| | meaty dithiane | FL/FR |
| 3- | mercapto-2-butanone | FL |
| 2- | mercaptomethyl pyrazine | FL |
| 2- | mercaptopropionic acid | FL/FR |
| 12- | methyl tridecanal | FL |
| bis(2- | methyl-3-furyl) disulfide | FL |
| S-(2- | methyl-3-furyl) ethane thioate | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| | pepperoni flavor | FL |
| | propyl 2-mercaptopropionate | FL |
| | propyl 2-methyl-3-furyl disulfide | FL |
| | pyrazinyl ethane thiol | FL |
| 2- | pyridinyl methane thiol | FL |
| | sulfuryl acetate | FL/FR |
| | thialdine | FL |
| ortho- | thiocresol | FL |
| ortho- | thioguaiacol | FL |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| musty |
| 2- | ethoxythiazole | FL |
| | hazelnut pyrazine | FL/FR |
| | menthofuran | FL/FR |
| nutty |
| 3,5- | diethyl-2-methyl pyrazine | FL |
| 2,5- | diethyl-3-methyl pyrazine | FL |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2,6- | lutidine | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| | nutty thiazole | FL |
| | tetrahydrofurfuryl alcohol | FL/FR |
| onion |
| | ethyl 2-mercaptopropionate | FL/FR |
| | furfuryl isopropyl sulfide | FL |
| | methyl propyl disulfide | FL |
| 2- | methyl-1,3-dithiolane | FL |
| popcorn |
| 2- | propionyl-2-thiazoline | FL |
| roasted |
| | ethyl 3-(furfuryl thio) propionate | FL |
| | hexyl mercaptan | FL |
| sausage |
| | sausage flavor | FL |
| savory |
| N-(2,4- | dimethoxybenzyl)-N2-(2-(pyridin-2-yl)ethyl) oxalamide | FL |
| N-( | heptan-4-yl)benzo(D)(1,3)dioxole-5-carboxamide | FL |
| N1-(2- | methoxy-4-methyl benzyl)-N2-(2-(pyridin-2-yl)ethyl) oxalamide | FL |
| N1-(2- | methoxy-4-methyl benzyl)-N2-2(2-(5-methyl pyridin-2-yl)ethyl) oxalamide | FL |
| spicy |
| hot spicy | beef flavor | FL |
| sulfurous |
| 2,3- | butane dithiol | FL |
| S- | ethyl thioacetate | FL |
| | fish thiol | FL/FR |
| | methyl 2-methyl-3-furyl disulfide | FL |
| | methyl mercaptan | FL/FR |
| 2- | methyl thiophene | FL |
| 3- | methyl-2-butane thiol | FL |
| 2- | naphthyl mercaptan | FL |
| | onion oil | FL/FR |
| | roasted butanol | FL |
| vegetable |
| | tyramine | FL |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | dimethyl thiofurane | | | furan, 2-methyl-3-(methylthio)- | | 2- | methyl-3-(methylsulfanyl)furan | | 2- | methyl-3-(methylthio)-furan | | 2- | methyl-3-(methylthio)furan | | 2- | methyl-3-methyl thiofuran | | 2- | methyl-3-methylsulfanylfuran | | 2- | methyl-3-methylthio furan | | 2- | methyl-3-methylthiofuran | | 2- | methyl-3-thiomethylfuran | | | methylmethylthiofuran |
Articles:
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