coffee difuran
2,2'-(dithiodimethylene)difuran
 
Notes:
Flavour component of roasted coffee, roasted sesame seeds and cooked meats. Flavouring ingredient
  • Advanced Biotech
    • Advanced Biotech. Inc.
      Inspired by Nature
      A diverse range of products, all meeting our stringent commitment to quality.
      Advanced Biotech is a leading manufacturer and supplier of high-quality Natural flavoring ingredients & botanical extracts for the food/beverage, cosmetic and personal care industries. With over 25 years of experience working with Fermentation processing & botanical extracts, we can help develop new innovative and functional products for today’s competitive marketplace. Our company prides itself in the ability to cater to our customer’s specific needs while maintaining our focus on integrity, honesty and the commitment to high quality product standards. We proudly offer our quality Natural ingredients to companies around the world.
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      1222 DIFURFURYL DISULFIDE NATURAL 95% min.
      SDS
      4019 DIFURFURYL DISULFIDE SYNTHETIC
      SDS
       
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
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  • Axxence Aromatic
    • Axxence Aromatic GmbH
      We bring nature to your flavour
      Dedicated to provide the best possible quality and supply service of natural aroma ingredients.
      Axxence Aromatic is entirely dedicated to provide the best possible quality and supply service of natural aroma ingredients to the Flavour & Fragrance Industry worldwide.
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      314600 DIFURFURYL DISULFIDE Natural Kosher
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
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      10262 Bis(2-Furfuryl)disulfide
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
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      Product(s):
      4437-20-1 Difurfuryl disulfide
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      DITHIODIMETHYLENE)DIFURAN, 2,2-( FEMA 3146
       
  • DeLong Chemicals America
    • DeLong Chemicals America
      Custom Manufacturing
      Supplier of aroma chemicals, pharmaceutical and specialty chemical intermediates.
      DeLong Chemicals America, LLC is an extension of Shijiazhuang Lida Chemical Co, Ltd to North America, a leading supplier and manufacturer of aroma chemicals, serving the industries of food, tobacco and perfume, while also providing intermediates, custom synthesis and custom manufacturing for pharmaceutical and specialty chemical industries.
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      Product(s):
      9823 2,2'-(Dithiodimethylene) difuran, Kosher
       
  • Endeavour Specialty Chemicals
    • Endeavour Specialty Chemicals Ltd
      Expertise in high impact aroma chemicals
      Endeavour Speciality Chemicals offers high-impact aroma chemicals, at small to medium scale.
      Speciality Chemical has more than 25 years experience of manufacturing high-impact aroma chemicals. With our core expertise in sulfur and heterocyclic chemistries, Endeavours products have applications in a range of industry sectors including flavours and fragrances, pharmaceutical research and material sciences. Endeavour also offer custom synthesis and contract manufacturing services at their UK manufacturing site.
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      SU0220 Difurfuryl disulphide 97% F&F
       
  • Excellentia International
    • Excellentia International
      Ingredients by Nature
      Exceptional quality and excellence in meeting our customers requirements.
      Excellentia International was founded in 2010 through the merger of Excellentia Flavors LLC and Polarome International. Collectively, these companies account for more than one hundred years of industry experience, and are recognized for exceptional quality and excellence in meeting our customers’ requirements.
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      Difurfuryl Disulfide Natural
       
  • FCI SAS
    • FCI SAS
      Inspired by Nature
      At FCI customer service is not a department it’s an attitude.
      Our team is composed of motivated professionals with great experience in the flavours and fragrances market. Our company has been serving this industry for more than 40 years and is ISO 9001 certified since 2009 . Whatever your question on flavour and fragrance ingredients: commercial, technical or regulatory – we will answer it very quickly.
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      Product(s):
      50041 DIFURFURYL DISULFIDE
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
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      US Voice: 845-341-2100
      US Fax: 845-341-2121
      Product(s):
      2-difurfuryl di-sulfide
       
  • H. Interdonati, Inc.
    • H. Interdonati, Inc.
      Innovative products
      Because your flavors and fragrances are only as good as their source "Since 1952"
      H. Interdonati, Inc. began in 1952 with the tradition of delivering quality pharmaceuticals and fine chemical ingredients at competitive prices. The mission was simple: To provide the most reliable, personal service in the industry.
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      US Email: Laura Interdonati (Sales)
      Voice: 800 367-6617
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      Product(s):
      Difuryldisulfide Kosher
       
  • Frutarom
    • FRUTAROM USA INC,
      Flavor & Specialty Ingredients
      Your preferred partner for flavour and fragrance success.
      Our broad and diverse product portfolio is designed to provide and cater for every flavor and taste profile required by our customer base and incorporates historic, and iconic, market leading products.
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      Product(s):
      441D145000 2,2-(DITHIODIMETHYLENE)-DIFURAN KOSHER
       
  • Indukern F&F
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
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      Product(s):
      HL0207 Difurfuryl disulphide
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
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      DIFURFURYL DISULFIDE NATURAL 96%
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
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      H0120 DIFURFURYL DISULFIDE, Kosher
       
  • Natural Advantage
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
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      US Email: Dean Matienzo
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      Product(s):
      Difurfuryl Disulphide
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      04-17600 DIFURFURYL DISULFIDE
      04-17605 DIFURFURYL DISULFIDE NATURAL
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
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      Product(s):
      W0467 Difurfuryl Disulfide
      W0467N NaturalDifurfuryl Disulfide
       
  • Taytonn
    • TAYTONN PTE LTD
      Supplying Asia Pacific
      We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
      Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
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      Product(s):
      2,2-(Dithiodimethylene)-Difuran
      Natural 2,2-Dithiodimethylenedifuran
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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      Product(s):
      D1384 Difurfuryl Disulfide >95.0%(GC)
       
  • Tianjin Danjun International
    • Tianjin Danjun International Trade Co., LTD.
      Quality Products
      We know the Chinese chemical market well.
      Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
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      Voice: +86-15822601686
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      Product(s):
      I-014 Bis(2-furfuryl)disulfide
       
  • R C Treatt & Co Ltd
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
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      Product(s):
      Difurfuryl disulphide Halal, Kosher

      Used in meat, soup, onion savory flavors; good in coffee and maple flavors. Normal use levels in finished consumer product: 0.01-1 ppm.
       
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
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      3005 Difurfuryl disulfide
       
  • Ernesto Ventós
  • WholeChem
    • WholeChem, LLC
      Connecting Innovators To the Building Blocks Of the Universe
      Custom manufacturer and distributor of specialty ingredients. We make global local.
      We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing.
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      Product(s):
      Difurfuryl disulphide
       
Synonyms   Articles   Notes   Search
    Flavor Demo Formulas
CAS Number: 4437-20-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 224-649-6
FDA UNII: 5IP6729ULF
Nikkaji Web: J68.898C
MDL: MFCD00010082
CoE Number: 11480
XlogP3-AA: 2.10 (est)
Molecular Weight: 226.31810000
Formula: C10 H10 O2 S2
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
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US Patents: Search
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JECFA Food Flavoring: 1081  2,2'-(dithiodimethylene)difuran
DG SANTE Food Flavourings: 13.050  difurfuryl disulfide
FEMA Number: 3146 2,2'-(dithiodimethylene)difuran
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):4437-20-1 ; 2,2'-(DITHIODIMETHYLENE) DIFURAN
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: pale yellow to amber clear oily liquid (est)
Assay: 96.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.22900 to 1.24800 @  25.00 °C.
Pounds per Gallon - (est).: 10.227 to 10.385
Refractive Index: 1.58500 to 1.59800 @  20.00 °C.
Melting Point: 10.00 to  11.00 °C. @ 760.00 mm Hg
Boiling Point: 229.00 to  230.00 °C. @ 760.00 mm Hg
Boiling Point: 112.00 to  115.00 °C. @ 0.50 mm Hg
Vapor Pressure: 0.000460 mmHg @ 25.00 °C. (est)
Vapor Density: 7.7 ( Air = 1 )
Flash Point: 212.00 °F. TCC ( 100.00 °C. )
logP (o/w): 4.030
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: refrigerate in tightly sealed containers.
Soluble in:
 alcohol
 water, 11.56 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 stable at room temp in most media
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: coffee
 
Odor Strength: high ,
recommend smelling in a 0.01 % solution or less
 
 sulfurous  coffee roasted coffee  roasted  chicken  meaty roasted meaty  onion  cabbage  
Odor Description:
at 0.01 % in propylene glycol. 
sulfury coffee roasted chicken meaty onion cabbage
 
 sulfurous  coffee  roasted  meaty  onion  cabbage  potato  
Odor Description:
at 0.01 %.  
Sulfurous, coffee, furfuryl mercaptan, roasted, meaty, onion and cabbage, potato
Mosciano, Gerard P&F 23, No. 5, 49, (1998)
 
 
Flavor Type: coffee
 
 sulfurous  coffee  roasted  meaty roasted meaty  onion  
Taste Description:
at 0.10 ppm.  
Sulfurous, coffee, roasted meaty, onion
Mosciano, Gerard P&F 23, No. 5, 49, (1998)
 
Odor and/or flavor descriptions from others (if found).
 
R C Treatt & Co Ltd
Difurfuryl disulphide Halal, Kosher
Odor Description: sulfurous; roast coffee, roast meat
Taste Description: Coffee, roasted, warm, malty notes at 2.5 ppm in water
Used in meat, soup, onion savory flavors; good in coffee and maple flavors. Normal use levels in finished consumer product: 0.01-1 ppm.
 
OQEMA
Difurfuryl Disulphide
Odor Description: sulfurous; roast coffee, roast meat
Taste Description: Coffee, roasted, warm, malty notes at 2.5 ppm in water
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Advanced Biotech
DIFURFURYL DISULFIDE NATURAL
95% min.
Odor: Roasted, Meaty
Advanced Biotech
DIFURFURYL DISULFIDE SYNTHETIC
Ambles Nature et Chimie
DIFURFURYL DISULFIDE NAT
Anhui Haibei
Difurfuryl Disulphide natural
Odor: Sulfury coffee roasted chicken meaty onion cabbage
Anhui Haibei
Difurfuryl Disulphide
Anhui Suzhou Jinli Aromatic Chemicals
Difurfuryl disulfide
Odor: caramel, baked meat, roast nut
Augustus Oils
2,2 (Dithiodimethylene) Difuran
Services
Aurochemicals
DIFURFURYL DISULFIDE 1% IN ETOH, Natural
Aurochemicals
DIFURFURYL DISULFIDE 1% IN PG, Natural
Aurochemicals
DIFURFURYL DISULFIDE, Natural
Axxence Aromatic
DIFURFURYL DISULFIDE Natural
Kosher
Sustainability
Beijing Lys Chemicals
Bis(2-Furfuryl)disulfide
BOC Sciences
For experimental / research use only.
Difurfuryl disulfide
Charkit Chemical
DITHIODIMETHYLENE)DIFURAN, 2,2-( FEMA 3146
DeLong Chemicals America
2,2'-(Dithiodimethylene) difuran, Kosher
Endeavour Specialty Chemicals
Difurfuryl disulphide 97% F&F
Speciality Chemical Product Groups
Ernesto Ventós
DIFURFURYL DISULPHIDE
Odor: POWERFUL, REPULSIVE, SULFUR, ROAST
Excellentia International
Difurfuryl Disulfide Natural
FCI SAS
DIFURFURYL DISULFIDE
Odor: Caramel, meat and coffee
Fleurchem
2-difurfuryl di-sulfide
Frutarom
2,2-(DITHIODIMETHYLENE)-DIFURAN
KOSHER
Flavor: Sulfurous, Coffee, Roasted, Chicken, Meaty, Onion, Cabbage
H. Interdonati, Inc.
Difuryldisulfide Kosher
Featured Products
IFF
2,2-(DITHIODIMETHYLENE)-DIFURAN
KOSHER
Flavor: Sulfurous, Coffee, Roasted, Chicken, Meaty, Onion, Cabbage
Indukern F&F
2-FURFURYL DISULPHIDE
Odor: POWERFUL, SULFUROUS, COFFEE, TOASTED
Jiangyin Healthway
Difurfuryl disulphide
New functional food ingredients
Jinan Enlighten Chemical Technology(Wutong Aroma )
Difurfuryl disulfide, Kosherk
Kingchem Laboratories
DIFURFURYL DISULFIDE (2,2'-(Dithiodimethylene)difuran)
Odor: Caramel, toast meat, nut
Lluch Essence
DIFURFURYL DISULFIDE NATURAL 96%
M&U International
DIFURFURYL DISULFIDE, Kosher
Natural Advantage
Difurfuryl Disulfide Nat, 10% in Neobee
Flavor: coffee, roasted, meaty, warm
Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries
Natural Advantage
Difurfuryl Disulfide Nat, 10% in OH
Flavor: coffee, roasted, meaty, warm
Natural Advantage
Difurfuryl Disulfide Nat
Flavor: coffee, roasted, meaty, warm
OQEMA
Difurfuryl Disulphide
Penta International
DIFURFURYL DISULFIDE NATURAL
Penta International
DIFURFURYL DISULFIDE
R C Treatt & Co Ltd
Difurfuryl disulphide
Halal, Kosher
Odor: sulfurous; roast coffee, roast meat
Flavor: Coffee, roasted, warm, malty notes at 2.5 ppm in water
Used in meat, soup, onion savory flavors; good in coffee and maple flavors. Normal use levels in finished consumer product: 0.01-1 ppm.
Riverside Aromatics
DIFURFURYL DISULPHIDE NATURAL
Robertet
DIFURFURYL DISULFIDE
Pure & Nat (EU)
Robinson Brothers
Difurfuryl disulphide F&F
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
Difurfuryl Disulfide
Sigma-Aldrich
2,2'-(Dithiodimethylene)difuran, ≥95%, FG
Certified Food Grade Products
Sunaux International
Difurfuryl Disulfide
Synerzine
Difurfuryl Disulfide
Synerzine
NaturalDifurfuryl Disulfide
Taytonn
2,2-(Dithiodimethylene)-Difuran
Odor: Burnt, Sulphurous, Coffee, Roast, Chiory
Taytonn
Natural 2,2-Dithiodimethylenedifuran
TCI AMERICA
For experimental / research use only.
Difurfuryl Disulfide >95.0%(GC)
Tengzhou Jitian Aroma Chemiclal
Difurfuryl disulfide
Tengzhou Xiang Yuan Aroma Chemicals
Difurfural Disulfide
Tianjin Danjun International
Bis(2-furfuryl)disulfide
United International
Difurfuryl disulfide
WholeChem
Difurfuryl disulphide
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for coffee difuran usage levels up to:
  0.1000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 3.30 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.70 (μg/capita/day)
NOEL (No Observed Effect Level): 3.00 (mg/kg bw per day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 4
Click here to view publication 4
 average usual ppmaverage maximum ppm
baked goods: -1.00000
beverages(nonalcoholic): -1.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -1.00000
condiments / relishes: -1.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.00000
fruit ices: -1.00000
gelatins / puddings: -1.00000
granulated sugar: --
gravies: -1.00000
hard candy: -1.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -1.00000
milk products: -1.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -1.00000
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009)
View page or View pdf
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 65, Revision 1 (FGE.65Rev1): Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated by EFSA in FGE.13Rev2 (2011)
View page or View pdf
Safety and efficacy of furfuryl and furan derivatives belonging to chemical group 14 when used as flavourings for all animal species and categories
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf
EPI System: View
EPA Substance Registry Services (TSCA): 4437-20-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 20499
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 2-(furan-2-ylmethyldisulfanylmethyl)furan
Chemidplus: 0004437201
Synonyms   Articles   Notes   Search   Top
References:
 2-(furan-2-ylmethyldisulfanylmethyl)furan
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 4437-20-1
Pubchem (cid): 20499
Pubchem (sid): 134985242
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB29988
FooDB: FDB001276
Export Tariff Code: 2932.19.5100
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
 chicory root 
roasted arabica coffee bean 
roasted congo coffee bean 
roasted bengal coffee bean 
roasted robusta coffee bean 
roasted coffea coffee bean 
roasted liberian coffee bean 
3,6-dimethyl pyrazine-2-thiol 
2,5-dimethyl-3-furfurylthio-pyrazine 
2,5-dimethyl-3,6-diethyl pyrazine 
2,6-dimethyl-gamma-thiopyrone 
2,6-dimethyl-thio-gamma-pyrone 
2-hydroxymethyl-6-methyl-pyridine 
4-hydroxymethyl-pyridine 
2-methyl-3-pentyl pyrazine 
(2-methylpyrazinyl-3, -5 and-6) furfuryl sulfide 
2-pentenyl furan 
2-(1-propenyl) pyridine 
2-(thienyl-2)-ethanethiol 
2,3,5-trimethyl phenolFR
 methyl furfuryl disulfideFL/FR
balsamic
2-acetyl furanFL/FR
(R)-2-methyl butyraldehyde 
 caramel furanone solutionFL/FR
 coffee dioneFL/FR
 cycloteneFL/FR
 fenugreek absoluteFL/FR
 fenugreek oleoresinFL/FR
5-methyl furfuralFL/FR
isopropenyl pyrazineFL/FR
chocolate
 cocoa hexenalFL/FR
2,6-dimethyl pyrazineFL/FR
2-methyl butyraldehydeFL/FR
2,4,5-trimethyl thiazoleFL/FR
coffee
 cappuccino fragranceFR
 cichorium intybus root extractFL/FR
 cichorium intybus root solid extractFL/FR
 coffea arabica fruit extractFL/FR
 coffea arabica seed extractFL/FR
roasted coffea arabica seed extractFL/FR
 coffea arabica seed oilFL/FR
 coffee absoluteFL/FR
arabica coffee bean butterFL/FR
roasted arabica coffee bean essenceFL/FR
roasted coffee bean extractFL/FR
roasted arabica coffee bean oilFL/FR
roasted arabica coffee bean oil CO2 extractFL/FR
 coffee bean oil extractFL/FR
 coffee fragranceFR
 coffee resinoidFL/FR
 furfuryl mercaptanFL/FR
1-hydroxy-2-butanoneFL/FR
2-methyl-3-,5 or 6-(furfuryl thio) pyrazineFL/FR
 nutty pyrazineFL/FR
6,8-dimethyl-2-nonanolFR
3-mercaptohexyl acetateFL/FR
(S)-2-methyl butyraldehyde 
 tropical thiazoleFL/FR
herbal
 thymyl methyl etherFL/FR
 wormwood oil americaFL/FR
 wormwood oil italyFL/FR
 wormwood oil polandFL/FR
 meaty dithianeFL/FR
4-methyl nonanoic acidFL/FR
medicinal
2,6-xylenolFL/FR
moldy
 strawberry furanone methyl etherFL/FR
 menthofuranFL/FR
nutty
3,5-cocoa pyrazineFL/FR
3,6-cocoa pyrazineFL/FR
2,3-dimethyl pyrazineFL/FR
4,5-dimethyl-2-ethyl-3-thiazolineFL/FR
2-ethyl pyrazineFL/FR
2-ethyl-4-methyl thiazoleFL/FR
 filbert heptenoneFL/FR
 filbert heptenone BFL/FR
2,6-lutidineFL/FR
5-methyl quinoxalineFL/FR
2-methyl thio-3,5 or 6-methyl pyrazineFL/FR
2-methyl-3-(methyl thio) pyrazineFL/FR
 sesame absoluteFL/FR
 sesame absolute CO2 extractFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
phenolic
para-alpha-dimethyl styreneFL/FR
popcorn
2-acetyl pyrazineFL/FR
 fenugreek resinoidFL/FR
 trigonella foenum-graecum seed oil CO2 extractFL/FR
sulfurous
 benzothiazoleFL/FR
 cocoa essenceFL/FR
 ethyl 3-mercaptobutyrateFL/FR
 fish thiolFL/FR
 furfuryl thioacetateFL/FR
S-furfuryl thioformateFL/FR
2-methyl 5-(methyl thio) furanFL/FR
O-methyl S-1-methoxyhexan-3-yl carbonothioateFL/FR
2-(methyl thio) phenolFL/FR
3-thiohexanolFL/FR
sweet
2-hydroxy-3,4,5-trimethyl-2-cyclopenten-1-oneFL/FR
vegetable
1-furfuryl pyrroleFL/FR
 tetrahydrofurfuryl alcoholFL/FR
woody
 juniper berry oleoresinFL/FR
2-methyl-3-isopropyl pyrazine 
 
For Flavor
 
No flavor group found for these
2-acetyl-6-methyl pyrazineFL
 benzyl methyl sulfideFL
1,2-butane dithiolFL
 coffea arabica fruit extractFL/FR
 dimethyl dihydrocyclopentapyrazineFL
(Z+E)-2,5-dimethyl-3-tetrahydrofuran thiolFL
(Z+E)-2,5-dimethyl-3-thioacetoxytetrahydrofuranFL
2,5-dimethyl-3-thiofuroyl furanFL
 ethyl 3-mercaptobutyrateFL/FR
2-formyl pyrroleFL
2-hydroxy-3,4,5-trimethyl-2-cyclopenten-1-oneFL/FR
3-mercapto-3-methyl butyl formateFL
(R)-2-methyl butyraldehyde 
(S)-2-methyl butyraldehyde 
 methyl dihydrofuran thiolFL
 methyl methane thiosulfonateFL
4-methyl-2-(methyl thiomethyl)-2-hexenalFL
2-methyl-3-,5 or 6-(furfuryl thio) pyrazineFL/FR
2-methyl-3-(methyl thio) pyrazineFL/FR
3-((2-methyl-3-furyl)thio)-4-heptanoneFL
isopropyl disulfideFL
 pyrazines mixtureFL
3,7-dimethyl-2,6-octadien-1-yl cyclopropyl carboxamideFL
2-methyl-1-methyl thio-2-buteneFL
absinthe
 absinthe flavorFL
alliaceous
 benzyl mercaptanFL
1,3-butane dithiolFL
 dicyclohexyl disulfideFL
3-mercapto-2-pentanoneFL
 tropical thiazoleFL/FR
bitter
2-hydroxymethyl-6-methyl-pyridine 
brown
 fenugreek oleoresinFL/FR
1-hydroxy-2-butanoneFL/FR
5-methyl furfuralFL/FR
burnt
 furfuryl alcoholFL
1-(2-furfuryl thio) propanoneFL
2-methyl quinoxalineFL
isopropenyl pyrazineFL/FR
2-(thienyl-2)-ethanethiol 
2,6-xylenolFL/FR
caramellic
 caramel furanoneFL
 caramel furanone solutionFL/FR
 cycloteneFL/FR
 fenugreek absoluteFL/FR
 fenugreek resinoidFL/FR
chocolate
 cocoa essenceFL/FR
 mocha cream flavorFL
cocoa
 cocoa hexenalFL/FR
coffee
 cappuccino flavorFL
 chicory flavorFL
 chicory root 
 chicory root distillatesFL
 chicory root essenceFL
roasted chicory root oilFL
 chicory tinctureFL
 cichorium intybus root extractFL/FR
 cichorium intybus root solid extractFL/FR
 coffea arabica seed extractFL/FR
roasted coffea arabica seed extractFL/FR
 coffea arabica seed oilFL/FR
 coffea canephora seed extractFL
 coffee absoluteFL/FR
roasted liberian coffee bean 
roasted congo coffee bean 
roasted arabica coffee bean 
roasted robusta coffee bean 
roasted coffea coffee bean 
roasted bengal coffee bean 
arabica coffee bean butterFL/FR
roasted coffee bean concentrateFL
roasted coffee bean essenceFL
roasted robusta coffee bean essenceFL
roasted arabica coffee bean essenceFL/FR
roasted robusta coffee bean extractFL
roasted coffee bean extractFL/FR
dried roasted coffee bean extractFL
roasted arabica coffee bean oil CO2 extractFL/FR
 coffee bean oil extractFL/FR
 coffee creme brulee flavorFL
 coffee dioneFL/FR
espresso coffee distillatesFL
 coffee distillatesFL
 coffee enhancersFL
espresso coffee essenceFL
espresso coffee extractFL
espresso coffee flavorFL
dark roast coffee flavorFL
 coffee flavorFL
irish coffee flavorFL
 coffee liqueur flavorFL
 coffee pyrazineFL
 coffee resinoidFL/FR
 coffee royale flavorFL
 difurfuryl etherFL
 diisoamyl thiomalateFL
3,6-dimethyl pyrazine-2-thiol 
2,4-dimethyl thiazoleFL
2,5-dimethyl-3-furfurylthio-pyrazine 
2,5-dimethyl-3,6-diethyl pyrazine 
2-ethyl-4-methyl thiazoleFL/FR
 furfuryl mercaptanFL/FR
 methyl furfuryl disulfideFL/FR
 methyl furfuryl mercaptopropionateFL
 methyl furfuryl thiolFL
2-methyl-5-vinyl pyrazineFL
2-isopropyl pyrazineFL
2-thiophene thiolFL
corn chip
2-acetyl-2-thiazolineFL
dairy
 creme brulle coffee flavorFL
earthy
 difurfuryl sulfideFL
(±)-2-mercapto-5-methylheptan-4-oneFL
2-methyl-3-isopropyl pyrazine 
eggy
isopropyl mercaptanFL
fatty
4-methyl nonanoic acidFL/FR
2,4-octadien-1-olFL
fruity
 furfuryl isobutyrateFL
 furfuryl isovalerateFL
 furfuryl propionateFL
fusel
2-methyl butyraldehydeFL/FR
green
3,4-dimethoxystyreneFL
2,6-dimethyl-gamma-thiopyrone 
2-methyl-5-isopropyl pyrazineFL
2-(1-propenyl) pyridine 
hazelnut
4-hydroxymethyl-pyridine 
herbal
 wormwood oil americaFL/FR
 wormwood oil italyFL/FR
 wormwood oil polandFL/FR
meaty
 benzothiazoleFL/FR
2,6-dimethyl thiophenolFL
1,1-ethane dithiol 1% in ethanol 94.5% / ethyl acetate 4%FL
 meaty dithianeFL/FR
3-mercapto-2-butanoneFL
(R,S)-2-mercapto-3-butanolFL
2-mercaptomethyl pyrazineFL
2-methyl 3-(methyl thio) furanFL
2-(methyl thio) phenolFL/FR
bis(2-methyl-3-furyl) disulfideFL
S-(2-methyl-3-furyl) ethane thioateFL
2-methyl-3-tetrahydrofuran thiolFL
2-methyl-3-thioacetoxytetrahydrofuranFL
roasted pork flavorFL
 propyl 2-mercaptopropionateFL
2-pyridinyl methane thiolFL
 thialdineFL
ortho-thiocresolFL
roast turkey flavorFL
molasses
 molasses blackstrapFL
moldy
 strawberry furanone methyl etherFL/FR
mustard
 furfuryl methyl etherFL
musty
2-ethoxythiazoleFL
 menthofuranFL/FR
2-methyl 5-(methyl thio) furanFL/FR
 thymyl methyl etherFL/FR
nutty
2-acetyl furanFL/FR
3,6-cocoa pyrazineFL/FR
3,5-cocoa pyrazineFL/FR
3,5(6)-cocoa pyrazineFL
2,6-dimethyl pyrazineFL/FR
2,3-dimethyl pyrazineFL/FR
4,5-dimethyl-2-ethyl-3-thiazolineFL/FR
2-ethyl pyrazineFL/FR
1-ethyl-2-acetyl pyrroleFL
 filbert heptenoneFL/FR
 filbert heptenone BFL/FR
2,6-lutidineFL/FR
5-methyl quinoxalineFL/FR
2-methyl thio-3,5 or 6-methyl pyrazineFL/FR
2-methyl-3-pentyl pyrazine 
 nutty pyrazineFL/FR
 nutty thiazoleFL
 sesame absoluteFL/FR
 sesame absolute CO2 extractFL/FR
 tetrahydrofurfuryl alcoholFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,4,5-trimethyl thiazoleFL/FR
onion
 furfuryl isopropyl sulfideFL
phenolic
2-ethyl benzene thiolFL
2-pentenyl furan 
roasted
2-acetyl pyrazineFL/FR
roasted arabica coffee bean oilFL/FR
3,5-diisobutyl-1,2,4-trithiolaneFL
2,6-dimethyl-thio-gamma-pyrone 
 ethyl 3-(furfuryl thio) propionateFL
 furfuryl thioacetateFL/FR
O-methyl S-1-methoxyhexan-3-yl carbonothioateFL/FR
(2-methylpyrazinyl-3, -5 and-6) furfuryl sulfide 
 trigonella foenum-graecum seed oil CO2 extractFL/FR
solvent
2-ethyl furanFL
 methyl phenyl sulfideFL
spicy
 cinnamon hazelnut cappuccino flavorFL
para-alpha-dimethyl styreneFL/FR
sulfurous
2,3-butane dithiolFL
 butyl mercaptanFL
 ethyl methyl sulfideFL
O-ethyl S-1-methoxyhexan-3-yl carbonothioateFL
S-ethyl thioacetateFL
 fish thiolFL/FR
S-furfuryl thioformateFL/FR
 furfuryl thiopropionateFL
3-methyl-2-butane thiolFL
 roasted butanolFL
2-thienyl mercaptanFL
3-thiohexanolFL/FR
tropical
3-mercaptohexyl acetateFL/FR
vegetable
1-furfuryl pyrroleFL/FR
woody
 juniper berry oleoresinFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 caramelFL
 chocolate cocoaFL
 coffeeFL
 garlicFL
 mapleFR
 meatFL
 nutFL
 onionFL
 potatoFL
 roastedFL
 savoryFL
 soupFL
 vegetableFL
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 beef boiled beef
Search  PMC Picture
 bread wheat bread
Search  PMC Picture
 coffee
Search  PMC Picture
 sesame seed roasted
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
2-difurfuryl di-sulfide
 difurfuryl disulfide
 difurfuryl disulfide (2,2'-(dithiodimethylene)difuran)
 difurfuryl disulfide natural
 difurfuryl disulfide synthetic
 difurfuryl disulphide
 difurfuryldisulfide
2,2'-[disulfanediylbis(methylene)]difuran
2,2'-(disulfanediyldimethanediyl)difuran
 disulfide, bis(2-furfuryl)
2,2'-(dithiobis(methylene)) bisfuran
2,2'-(dithiobis(methylene))bisfuran
2,2'-[dithiobis(methylene)]bisfuran
2,2'-(dithiodimethylene) difuran
2,2-(dithiodimethylene) difuran
2,2'-(dithiodimethylene)-difuran
2,2-(dithiodimethylene)-difuran
2,2'-(dithiodimethylene)difuran
2,2-(dithiodimethylene)difuran
 furan, 2,2'- dithiobis(methylene) bis-
 furan, 2,2'-(dithiobis(methylene))bis-
 furan, 2,2'-(dithiodimethylene)di-
2-(furan-2-ylmethyldisulfanylmethyl)furan
2-furfuryl disulfide
bis 2-furfuryl disulfide
2-furfuryl disulphide
bis(2-furfuryl) disulfide
bis(2-furfuryl)disulfide
 robustone (IFF)
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Synonyms   Articles   Notes   Search   Top
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