dextro,laevo-muscone
3-methyl-1-cyclopentadecanone
 
Notes:
Incredible fixer. Flavouring ingredient Muscone is an organic compound that is the primary contributor to the odor of musk.
  • ACS International
    • ACS International GmbH
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      Our hybrid business model, combining manufacturing with sourcing and exclusive distribution agreements, results in a superior level of purchasing power that when added to our global warehouse network with locations near all major flavor and fragrance industry compounding centers around the globe, make A.C.S. International your one-stop sourcing partner.
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      Product(s):
      72022 Muscone
      23903 Muscone
       
  • Augustus Oils
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    • Azelis UK Ltd.
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      962195 MUSCONE
       
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      541-91-3 Muscone >98%
       
  • Firmenich
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      962195 MUSCONE for fragrance
      It can be used to give elegant and warm animal notes and adds lift and diffusion to any perfume. Important for the reconstitution of natural musk.
       
       
  • Indukern F&F
  • Lluch Essence
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      Flexibility, availability, price and quality.
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      MUSCONE
       
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      A0644 Muscone
       
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  • Pell Wall Perfumes
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      According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”.
       
       
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      13-37700 3-METHYL-1-CYCLOPENTADECANONE
       
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      MUSCONE (> 95%)
       
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      M2611 Muscone >97.0%(GC)
      SDS
       
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Synonyms   Articles   Notes   Search
Fragrance Demo Formulas
CAS Number: 541-91-3Picture of molecule3D/inchi
Other(deleted CASRN): 22460-48-6
ECHA EINECS - REACH Pre-Reg: 208-795-8
FDA UNII: 5JO79R7S9R
Nikkaji Web: J6.397E
MDL: MFCD00211114
CoE Number: 11135
XlogP3-AA: 6.20 (est)
Molecular Weight: 238.41430000
Formula: C16 H30 O
NMR Predictor: Predict (works with chrome, Edge or firefox)
EFSA/JECFA Comments: JECFA name: 3-Methyl-1-cyclopentadecanone.
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 1402  3-methyl-1-cyclopentadecanone
FEMA Number: 3434 3-methyl-1-cyclopentadecanone
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):541-91-3 ; 3-METHYL-1-CYCLOPENTADECANONE
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless clear liquid (est)
Assay: 97.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 0.91800 to 0.92500 @  25.00 °C.
Pounds per Gallon - (est).: 7.639 to  7.697
Refractive Index: 1.47700 to 1.48100 @  20.00 °C.
Melting Point: 8.60 °C. @ 760.00 mm Hg
Boiling Point: 320.00 to  329.00 °C. @ 760.00 mm Hg
Boiling Point: 130.00 °C. @ 0.50 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure: 0.000176 mmHg @ 25.00 °C. (est)
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 6.100 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
 alcohol
 water, very slightly
 water, 0.2213 mg/L @ 25 °C (est)
Stability:
 APC: -
 candle: traces - 0.5%
 detergent: traces - 0.5%
 fine fragrances: 0.1 - 2%
 shampoo: traces - 0.5%
 shower gel: traces - 0.5%
 soap: traces - 0.5%
 softener: traces - 0.5%
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: musk
 
Odor Strength: high ,
recommend smelling in a 10.00 % solution or less
 
Substantivity: 400 hour(s) at 100.00 %
 
 sweet  musk  animal  powdery  fatty  natural  
Odor Description:
at 10.00 % in dipropylene glycol. 
sweet musk animal powdery fatty natural
Luebke, William tgsc, (1986)
 
 sweet  floral  musk  soapy  
Odor Description:
at 0.20 %.  
sweet fragrant perfume, musky with floral and soapy shaving cream like nuances.
Mosciano, Gerard, (2009)
 
 
Flavor Type: musk
 
 sweet  musk  floral  soapy  woody  bitter  
Taste Description:
at 1.00 ppm.  
sweet, musk like, perfume, soapy with woody and bitter nuances
Mosciano, Gerard, (2009)
 
Odor and/or flavor descriptions from others (if found).
 
Firmenich
MUSCONE for fragrance
Odor Description: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk
It can be used to give elegant and warm animal notes and adds lift and diffusion to any perfume. Important for the reconstitution of natural musk.
 
Pell Wall Perfumes
Muscone
Odor Description: Musk, powdery, soft, animalic. Exalting. Fixative
According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”.
 
IFF
Muscor
Odor Description: Soft, sweet, musky with animalic tonalities
 
Perfumery Laboratory
MUSCON LAEVO 20% Firmenich (MUSCONE LAEVO 954117 Firmenich)
Odor Description: trong aroma of Thonky musk, which has good diffusion
 
Takasago
l-Muscone
Odor Description: musk animal powdery
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
ACS International
Muscone
Operational Capabilities
ACS International
Muscone
Odor: sweet musk floral woody soapy
Alfa Biotechnology
For experimental / research use only.
Muscone 98%
Augustus Oils
Muscone
Services
Azelis UK
MUSCONE
BOC Sciences
For experimental / research use only.
Muscone >98%
Coompo
For experimental / research use only.
Muscone from Plants ≥98%
Ernesto Ventós
MUSCONE FIRMENICH 962195
Odor: VERY SOFT, SWEET, MUSKY
Ernesto Ventós
MUSCOR IFF
Fine Fragrances Pvt Ltd
Muscone
Firmenich
MUSCONE
for fragrance
Odor: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk
Use: It can be used to give elegant and warm animal notes and adds lift and diffusion to any perfume. Important for the reconstitution of natural musk.
IFF
Muscor
Odor: Soft, sweet, musky with animalic tonalities
Indukern F&F
MUSCONE
Odor: SMOOTH, SWEET, MUSK
Liaison Carbone
MUSCONE LAEVO 954117
Lluch Essence
MUSCONE
M&U International
Muscone
Moellhausen
MUSCONE
Odor: musky, slightly fruity, erogenic
Pell Wall Perfumes
Muscone
Odor: Musk, powdery, soft, animalic. Exalting. Fixative
Use: According to Arcadi Boix Camps it “has a smooth, brilliant aroma, not overly animal-like and very beautiful. It is perceptible in very small amounts and its fixation is so extreme that it seems incredible. Although it doesn’t substitute completely for the natural product, it is equal to it on the lasting properties. We can consider it outstanding and it imparts great elegance”.
Penta International
3-METHYL-1-CYCLOPENTADECANONE
Perfumer Supply House
L-Muscone (Takasago) – for a limited time
Odor: The key component of musk, this synthetic version has a sweet, powdery, animalic aroma
Perfumery Laboratory
MUSCON LAEVO 20% Firmenich (MUSCONE LAEVO 954117 Firmenich)
Odor: trong aroma of Thonky musk, which has good diffusion
Prodasynth
MUSCONE
(> 95%)
Odor: SOFT, SWEET, MUSKY
Santa Cruz Biotechnology
For experimental / research use only.
Muscone ≥98%
Takasago
l-Muscone
Odor: musk animal powdery
The Fragrance Museum
TCI AMERICA
For experimental / research use only.
Muscone >97.0%(GC)
Tianjin Danjun International
3-Methyl-1-cyclopentadecanone
Vigon International
Muscone
Odor: A very soft, sweet, musky odor with a warm animal tonality, reminiscent of the natural Tonkin musk
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
30 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50  [sex: M,F] > 5000 mg/kg
(Oh et al., 1997)

intravenous-mouse LD50  152 mg/kg
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 12, Pg. 236, 1981.

intraperitoneal-mouse LD50  270 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 12, Pg. 236, 1981.

oral-rat LD50  > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 749, 1982.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 749, 1982.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for dextro,laevo-muscone usage levels up to:
  2.0000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.37 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.009 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 8
Click here to view publication 8
 average usual ppmaverage maximum ppm
baked goods: -0.05000
beverages(nonalcoholic): -0.03000
beverages(alcoholic): -0.02000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: -0.05000
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.03000
fruit ices: -0.03000
gelatins / puddings: -0.02000
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of alicyclic substances used as flavor ingredients. View pdf
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 9, Revision 1: (FGE.09 Rev1)[1] - Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical groups 8 and 30, and an ester of a phenol carboxylic acid from chemical group 25 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 9, Revision 2 (FGE.09Rev2): Secondary alicyclic saturated and unsaturated alcohols, ketones and esters containing secondary alicyclic alcohols from chemical group 8 and 30, and an ester of a phenol derivative from chemical group 25
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 541-91-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 10947
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 3-methylcyclopentadecan-1-one
Chemidplus: 0000541913
RTECS: GY0950000 for cas# 541-91-3
Synonyms   Articles   Notes   Search   Top
References:
Leffingwell: Chirality or Article
 3-methylcyclopentadecan-1-one
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 541-91-3
Pubchem (cid): 10947
Pubchem (sid): 134976141
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): HMDB34181
FooDB: FDB012473
Export Tariff Code: 2914.29.5000
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
the dried, unopened pouches of commerce are distinguished by the following names: tonquin, blue skin, yunnann, sawko, cabardin, nepal, & assam. good quality pouches contain approx 70% musk, while less valuable ones contain as little as 40% musk. musk
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
aldehydic
 citronellyl oxyacetaldehydeFL/FR
9-decenalFL/FR
 dodecanal (aldehyde C-12 lauric)FL/FR
10-undecenal (aldehyde C-11 undecylenic)FL/FR
amber
 ambergris naphtholFR
 ambrette seed oilFL/FR
 ambrinolFR
alpha-ambrinolFL/FR
 ambroxanFL/FR
 angelica root oilFL/FR
 cistus ladaniferus resinoidFL/FR
animal
 animal carbolactoneFR
 animal specialtyFR
isobutyl quinolineFR
isobutyl quinolineFR
para-cresyl caprylateFL/FR
 musk indenofuranFR
 procavia capensis excrete absoluteFR
anisic
para-anisaldehydeFL/FR
balsamic
isoamyl benzoateFL/FR
 amyris wood oilFL/FR
siam benzoin resinoidFL/FR
 benzophenoneFR
 benzyl cinnamateFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
isobutyl cinnamateFL/FR
 cinnamyl alcoholFL/FR
 clover nitrileFR
 ethyl cinnamateFL/FR
 fir balsam absoluteFR
 methyl cinnamateFL/FR
3-phenyl propyl alcoholFL/FR
berry
 raspberry ketoneFL/FR
 raspberry ketone acetateFL/FR
 raspberry ketone methyl etherFL/FR
caramellic
 ethyl maltolFL/FR
citrus
 bergamot oilFL/FR
 grapefruit pentanolFR
blood orange oil italyFL/FR
earthy
 muscogeneFR
fatty
 decanolFL/FR
floral
alpha-amyl cinnamaldehydeFL/FR
isoamyl salicylateFL/FR
 benzyl acetateFL/FR
 bois de rose oil brazilFL/FR
isobutyl salicylateFL/FR
 citronellolFL/FR
 coriander seed oilFL/FR
 cyclamen aldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
alpha-damasconeFL/FR
9-decen-1-olFL/FR
 dimethyl benzyl carbinolFL/FR
 ethyl phenyl acetateFL/FR
 floral pyranolFR
 gardenia oxideFR
 geraniolFL/FR
 heliotropinFL/FR
 heliotropyl diethyl acetalFR
(Z)-3-hexen-1-yl salicylateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 hyacinth etherFR
 hydroxycitronellalFL/FR
(Z)-jasmoneFL/FR
 leerallFR
 lilyallFR
 linaloolFL/FR
laevo-linaloolFL/FR
 linalool oxideFL/FR
para-methyl acetophenoneFL/FR
 methyl dihydrojasmonateFL/FR
 muguet carboxaldehydeFR
 muguet octadienolFR
 nerolFL/FR
 nerolidolFL/FR
 nonanolFL/FR
 ocean propanalFL/FR
 orris pyridine 25% IPMFR
 peony alcoholFR
 phenethyl alcoholFL/FR
 phenethyl isobutyrateFL/FR
 phenethyl phenyl acetateFL/FR
 phenethyl propionateFL/FR
 phenethyl salicylateFL/FR
 rhodinolFL/FR
 rose butanoateFL/FR
 tetrahydrolinaloolFL/FR
 violet methyl carbonateFR
fresh
10-undecen-1-yl acetateFL/FR
fruity
 allyl amyl glycolateFR
 benzyl propionateFL/FR
beta-damasconeFL/FR
gamma-decalactoneFL/FR
 green acetateFR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
green
(Z)-3-hexen-1-yl acetateFL/FR
(Z)-3-hexen-1-yl benzoateFL/FR
(Z)-3-hexen-1-yl propionateFL/FR
(Z)-leaf acetalFL/FR
 melon nonenoateFL/FR
 valerian rhizome oil CO2 extract chinaFL/FR
 violet leaf absoluteFL/FR
hay
 beeswax absoluteFL/FR
 hay absoluteFR
herbal
 clary sage oil franceFL/FR
 daucus carota fruit oilFL/FR
 lavender absolute bulgariaFL/FR
 linalyl acetateFL/FR
 valerian rhizome oilFL/FR
 valerian rhizome oil chinaFL/FR
honey
 methyl phenyl acetateFL/FR
melon
 watermelon ketoneFR
mossy
 oakmoss absoluteFL/FR
 veramoss (IFF)FR
musk
(Z)-ambrettolideFL/FR
(3alpha,5alpha)-androst-16-en-3-olFR
 cyclohexadecanoneFR
 ethylene dodecanoateFR
 exaltone (Firmenich)FR
 juniper musconeFR
delta-muscenoneFR
(R)-musconeFR
 musk amberolFR
 musk cyclopentenyl propionateFR
 musk dimethyl indaneFL/FR
 musk indaneFR
 musk nonaneFR
(Z)-musk pentaneFR
 musk tetralinFL/FR
 musk tibetene (Givaudan)CS
 musk xylolCS
omega-pentadecalactoneFL/FR
 polvolide (Soda)FR
naphthyl
beta-naphthyl ethyl etherFL/FR
powdery
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
spicy
 clove bud oilFL/FR
black currant bud absoluteFL/FR
 methyl isoeugenolFL/FR
terpenic
 frankincense oilFL/FR
alpha-terpineolFL/FR
tonka
 coumarinFR
 tonka bean absoluteFR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
waxy
 decyl acetateFL/FR
1-dodecanolFL/FR
 ethyl laurateFL/FR
1-undecanolFL/FR
woody
 amber carbinolFR
 cistus twig/leaf oilFL/FR
 guaiacwood oilFL/FR
 gurjun balsam oilFR
 longifoleneFL/FR
 methyl cedryl ketoneFL/FR
 patchouli ethanoneFR
 patchouli oilFL/FR
 santallFR
 tobacarol (IFF)FR
 vetiver oil haitiFL/FR
 woody acetateFR
(Z)-woody amyleneFR
 woody propanolFR
 
For Flavor
 
No flavor group found for these
(Z)-ambrettolideFL/FR
 cistus ladaniferus resinoidFL/FR
9-decenalFL/FR
beta-damasconeFL/FR
aldehydic
1-undecanolFL/FR
amber
 ambrette seed oilFL/FR
alpha-ambrinolFL/FR
 musk tetralinFL/FR
animal
para-cresyl caprylateFL/FR
balsamic
siam benzoin resinoidFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
isobutyl cinnamateFL/FR
 ethyl cinnamateFL/FR
berry
 raspberry ketoneFL/FR
 raspberry ketone acetateFL/FR
 raspberry ketone methyl etherFL/FR
brown
 beeswax absoluteFL/FR
caramellic
 ethyl maltolFL/FR
cherry
 heliotropinFL/FR
citrus
 bergamot oilFL/FR
 citronellyl oxyacetaldehydeFL/FR
 linaloolFL/FR
laevo-linaloolFL/FR
 nerolFL/FR
blood orange oil italyFL/FR
alpha-terpineolFL/FR
cooling
isobutyl salicylateFL/FR
creamy
para-anisaldehydeFL/FR
para-methyl acetophenoneFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
fatty
(Z)-3-hexen-1-yl benzoateFL/FR
10-undecenal (aldehyde C-11 undecylenic)FL/FR
floral
 bois de rose oil brazilFL/FR
 citronellolFL/FR
 geraniolFL/FR
 linalyl acetateFL/FR
 methyl dihydrojasmonateFL/FR
 methyl phenyl acetateFL/FR
 ocean propanalFL/FR
 phenethyl alcoholFL/FR
 phenethyl propionateFL/FR
 rhodinolFL/FR
 tetrahydrolinaloolFL/FR
fruity
isoamyl benzoateFL/FR
para-anisyl acetateFL/FR
para-anisyl alcoholFL/FR
 benzyl acetateFL/FR
 benzyl propionateFL/FR
alpha-damasconeFL/FR
gamma-decalactoneFL/FR
 rose butanoateFL/FR
 valerian rhizome oilFL/FR
 valerian rhizome oil chinaFL/FR
 valerian rhizome oil CO2 extract chinaFL/FR
greasy
10-undecen-1-yl acetateFL/FR
green
isoamyl salicylateFL/FR
 angelica root oilFL/FR
 cinnamyl alcoholFL/FR
 cyclamen aldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
(Z)-3-hexen-1-yl acetateFL/FR
(Z)-3-hexen-1-yl propionateFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
(Z)-leaf acetalFL/FR
 linalool oxideFL/FR
 melon nonenoateFL/FR
 nerolidolFL/FR
 oakmoss absoluteFL/FR
 violet leaf absoluteFL/FR
herbal
 clary sage oil franceFL/FR
 coriander seed oilFL/FR
 daucus carota fruit oilFL/FR
 lavender absolute bulgariaFL/FR
honey
 ethyl phenyl acetateFL/FR
 phenethyl isobutyrateFL/FR
 phenethyl phenyl acetateFL/FR
medicinal
 dimethyl benzyl carbinolFL/FR
 phenethyl salicylateFL/FR
musk
 musk dimethyl indaneFL/FR
powdery
beta-naphthyl ethyl etherFL/FR
roasted
 acer spicatum bark extractFL
soapy
 dodecanal (aldehyde C-12 lauric)FL/FR
1-dodecanolFL/FR
spicy
 benzyl cinnamateFL/FR
 clove bud oilFL/FR
black currant bud absoluteFL/FR
 methyl cinnamateFL/FR
 methyl isoeugenolFL/FR
3-phenyl propyl alcoholFL/FR
tropical
alpha-amyl cinnamaldehydeFL/FR
vanilla
 ethyl vanillinFL/FR
omega-pentadecalactoneFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
waxy
 decanolFL/FR
9-decen-1-olFL/FR
 decyl acetateFL/FR
 ethyl laurateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 hydroxycitronellalFL/FR
 nonanolFL/FR
woody
 ambroxanFL/FR
 amyris wood oilFL/FR
 cistus twig/leaf oilFL/FR
 frankincense oilFL/FR
 guaiacwood oilFL/FR
(Z)-jasmoneFL/FR
 longifoleneFL/FR
 methyl cedryl ketoneFL/FR
 patchouli oilFL/FR
 vetiver oil haitiFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 acaciaFR
 amberFR
 ambergrisFR
 ambrette oil replacerFR
 angelicaFL/FR
 animalFR
 autumnFR
 azaleaFR
 balsamFR
 barkFR
 bayberryFR
 beeswax absolute replacerFR
 boroniaFR
 bouquetFR
 cabreuva woodFR
 cassia blossomFR
 cedarFR
 cedar forestFR
 champacaFR
 chocolate cacaoFL
 chypreFR
 cistusFL/FR
 civetFR
 clean 
 cloverFR
 coloniaFR
 country meadowFR
 cyclamenFR
 daffodilFR
 daphneFR
 dogwoodFR
 dusty 
 fantasy blends 
 fernFR
 figFR
 fir balsamFR
 fir needle oil replacerFR
 fixer 
 floralFR
 flouveFR
 flouve blossomFR
 foliageFR
 frangipani plumeriaFR
 freesiaFR
 genetFR
 ginger white gingerFR
 guaiacwoodFL/FR
 gurjun balsamFR
 hawthornFR
 hay new mown hayFR
 heatherFR
 herbalFR
 hinoki oil replacerFR
 hollyberryFR
 hugoniaFR
 immortelleFL/FR
 incenseFR
 kiwi blossomFR
 labdanumFR
 lavenderFR
 leatherFR
 lilyFR
 lily of the valleyFR
 lotusFR
 millefleursFR
 mimosaFR
 mossFR
 muskFR
 muskrat 
 narcissusFR
 oakwoodFR
 ocean seaFR
 orange blossomFR
 orchidFR
 orientalFR
 pansyFR
 passion blossomFR
 patchouliFR
 petuniaFR
 phloxFR
 pineFR
 pine forestFR
 poppyFR
 powderFR
 privet blossomFR
 rainFR
 resedaFR
 roseFR
 rose d'orientFR
 rose red roseFR
 rose tea roseFR
 rose white roseFR
 rose wild rose 
 sandalwoodFR
 soapy sandalwood mossFR
 spiceFR
 spring rainFR
 stephanotisFR
 sweet grassFR
 timber 
 tobaccoFR
 tonka beanFR
 tulipFR
 vanillaFR
 wisteriaFR
 woodruffFR
 woodyFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 musk natural
Search  PMC Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 cyclopentadecanone, 3-methyl-
3-methyl cyclopentadecan-1-one
3-methyl cyclopentadecanone
 methyl exaltone
3-methyl-1-cyclopentadecanone
3-methyl-cyclopentadecanone
3-methylcyclopentadecan-1-one
3-methylcyclopentadecanone
 methylexaltone
 moschus ketone
dextro,laevo-muscone
DL-muscone
 muscone (Firmenich)
 muscor (IFF)
 muskone
Synonyms   Articles   Notes   Search   Top
Articles:
Info: Muscone
PubMed: Administration of BMSCs with Muscone in Rats with Gentamicin-Induced AKI Improves Their Therapeutic Efficacy.
PubMed: Beneficial effects of muscone on cardiac remodeling in a mouse model of myocardial infarction.
PubMed: Chinese herbs and their active ingredients for activating xue (blood) promote the proliferation and differentiation of neural stem cells and mesenchymal stem cells.
PubMed: Neuroprotective effect of muscone on glutamate-induced apoptosis in PC12 cells via antioxidant and Ca(2+) antagonism.
PubMed: Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors.
PubMed: Anti-inflammatory effects of 4-methylcyclopentadecanone on edema models in mice.
PubMed: Effects of Qishe Pill, a compound traditional Chinese herbal medicine, on cervical radiculopathy: study protocol for a randomized controlled trial.
PubMed: Influence of borneol and muscone on geniposide transport through MDCK and MDCK-MDR1 cells as blood-brain barrier in vitro model.
PubMed: Metabolomic strategy for studying the intervention and the synergistic effects of the shexiang baoxin pill for treating myocardial infarction in rats.
PubMed: Fast and direct quantification of underivatized muscone by ultra performance liquid chromatography coupled with evaporative light scattering detection.
PubMed: [Effect of borneol on intestinal absorption of muscone in rats].
PubMed: [Analysis of muscone from serum and cerebrospinal fluid of rabbits after intragastric administration of tongqiao huoxue granules].
PubMed: [Determination method of muscone in rat intestinal perfusate by GC-MS/MS and its intestinal absorption kinetic characteristics in rats].
PubMed: Muscone exerts neuroprotection in an experimental model of stroke via inhibition of the fas pathway.
PubMed: Efficient macrocyclization by a novel oxy-oxonia-Cope reaction: synthesis and olfactory properties of new macrocyclic musks.
PubMed: Protective effects of muscone on ischemia-reperfusion injury in cardiac myocytes.
PubMed: Fragrance material review on 3-methyl-1-cyclopentadecanone.
PubMed: Catalytic asymmetric Michael reactions of α,β-unsaturated ketones with sulfonyl-containing nucleophiles: chiral synthesis of (R)-muscone and (S)-celery ketone.
PubMed: Dynamic octopus amphiphiles as powerful activators of DNA transporters: differential fragrance sensing and beyond.
PubMed: Synthesis of omega-hydroxy carboxylic acids and alpha,omega-dimethyl ketones using alpha,omega-diols as alkylating agents.
PubMed: (+)-(R,Z)-5-Muscenone and (-)-(R)-muscone by enantioselective aldol reaction and Grob fragmentation.
PubMed: [Protective effects and machanism of muskone on pheochromocytoma cell injure induced by glutamate].
PubMed: Muscone protects vertebral end-plate degeneration by antiinflammatory property.
PubMed: Efficient formation of ring structures utilizing multisite activation by indium catalysis.
PubMed: Comparison of the therapeutic effects of different compositions of muskone in the treatment of experimental myocardial infarct in rats and analgesia in mice.
PubMed: Synthesis of l-muscone by asymmetric methylation via enol esters.
PubMed: Synthetic applications of enantioselective protonation and case study for (S)-alpha-damascone.
PubMed: A three-carbon (n+1+2) ring expansion method for the synthesis of macrocyclic enones. Application to muscone synthesis.
PubMed: [Effects of series of Muskone on heart hemodynamics and myocardial consumption of oxygen in experimental dogs].
PubMed: [Study on therapeutic effects of series of muskone on myocardial infarction canines].
PubMed: Enantioselective intramolecular aldol addition/dehydration reaction of a macrocyclic diketone: synthesis of the musk odorants (R)-muscone and (R,Z)-5-muscenone.
PubMed: [Study on comparative pharmacology of series of Muskone].
PubMed: Normal-phase chiral liquid chromatography-mass spectrometry of non-UV-active compounds: applications for pharmaceutically relevant racemates.
PubMed: [Determination of muscone in Xingnaojing injection by gas chromatography with solid phase microextraction].
PubMed: CpRu(PN) complex-catalyzed isomerization of allylic alcohols and its application to the asymmetric synthesis of muscone.
PubMed: Ti-crossed-Claisen condensation between carboxylic esters and acid chlorides or acids: a highly selective and general method for the preparation of various beta-keto esters.
PubMed: [Study of diffusion of muscone in different inclusion complexes and liposome through mouse (correction of rat) skin in vitro].
PubMed: Characterization of allegedly musk-containing medicinal products in Taiwan.
PubMed: [An experimental study on distribution of musk into the brain through blood brain barrier].
PubMed: Solid-phase extraction of L-muscone from aqueous samples with Amberlite XAD-4 for gas chromatographic assay.
PubMed: Psychological effects of musky compounds: comparison of androstadienone with androstenol and muscone.
PubMed: Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells.
PubMed: Synthesis of (R)- and (S)- muscone.
PubMed: Solid phase synthesis of complex natural products and libraries thereof.
PubMed: Enantioselectivity of the musk odor sensation.
PubMed: [Quantitative analysis of muscone in shexiang baoxin pills by gas chromatography].
PubMed: [Pharmacokinetics of muscone in rats, rabbits and dogs].
PubMed: [Determination of major volatile components in suhexiang wan (storax pill) using analytical supercritical fluid extraction (SFE)].
PubMed: [A preliminary research on the quality of musk].
PubMed: Characterization of liver microsomal cytochrome P450 from rats treated with muscone (3-methylcyclopentadecanone).
PubMed: [Analysis of musk rheumatic oil by GC/FTIR].
PubMed: [Method of analysis for musk, artificially bred musk and original musk by HPLC].
PubMed: Induction of cytochrome P-450 and related drug-oxidizing activities in muscone (3-methylcyclopentadecanone)-treated rats.
PubMed: [Determination of muscone contents in Chinese drug preparations containing Moschus by the TLC scanning method].
PubMed: Musk deer (Moschus moschiferus): Reinvestigation of main lipid components from preputial gland secretion.
PubMed: Pharmacological properties of musk.
PubMed: Induction of rat liver microsomal cytochrome P-450 by muscone (3-methylcyclopentadecanone).
PubMed: [Mass spectrography analysis on the components of a substance obtained from the male musk-rat].
PubMed: [Quantitative analysis of muscone in musk by GC].
PubMed: [The analysis of synthetic muscone (DL-3-methylcyclopentadecanone) and its impurities (author's transl)].
PubMed: Insect and mammalian pheromones.
PubMed: Many-membered carbon rings; a new synthesis of civetone and dl-muscone.
PubMed: [Not Available].
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