|
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white to pale yellow solid (est) |
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 37.00 to 40.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 193.00 to 195.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 72.00 to 74.00 °C. @ 10.00 mm Hg
|
| Vapor Pressure: | 0.452000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 3.9 ( Air = 1 ) |
| Flash Point: | 184.00 °F. TCC ( 84.44 °C. )
|
| logP (o/w): | 0.252 (est) |
| Soluble in: |
| | alcohol | | | water | | | water, 2.679e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| |
| Odor Type: nutty |
| |
| Odor Strength: | medium |
| |
| Substantivity: | > 19 hour(s) at 100.00 % |
| |
| | sweet acorn nut skin maple caramellic brothy |
Odor Description: at 10.00 % in dipropylene glycol. | sweet acorn nut skin maple caramel brothy Luebke, William tgsc, (2009) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Cyclohexane-1,2-dione 98%
|
| Endeavour Specialty Chemicals |
| 1,2-Cyclohexanedione 98% F&F
|
| Speciality Chemical Product Groups |
| Penta International |
| 1,2-CYCLOHEXANEDIONE
|
| R C Treatt & Co Ltd |
| 1,2-Cyclohexanedione
Halal, Kosher |
| Robinson Brothers |
| 1,2-Cyclohexanedione
|
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 1,2-Cyclohexanedione
|
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| 1,2-Cyclohexanedione 97%
|
| Synerzine |
| 1,2-Cyclohexanedione
|
| TCI AMERICA |
| For experimental / research use only. |
| 1,2-Cyclohexanedione >97.0%(GC)
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 22 - Harmful if swallowed. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
Safety References:
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| No odor group found for these |
| | sulfuryl octanoate | FL/FR |
| | sulfuryl butyrate | FL/FR |
| | sulfuryl decanoate | FL/FR |
| | sulfuryl hexanoate | FL/FR |
| | sulfuryl isobutyrate | FL/FR |
| | sulfuryl propionate | FL/FR |
| | valeraldehyde dibutyl acetal | FL/FR |
| | valeraldehyde propylene glycol acetal | FL/FR |
| animal |
| | costus valerolactone | FR |
| balsamic |
| | propyl benzoate | FL/FR |
| | terpinyl cinnamate | FL/FR |
| bready |
| | coffee furanone | FL/FR |
| buttery |
| | acetyl propionyl | FL/FR |
| 3,4- | hexane dione | FL/FR |
| camphoreous |
| | bornyl isobutyrate | FL/FR |
| | butyrophenone | FL/FR |
| | caramel furanone solution | FL/FR |
| | caramel pentadione | FL/FR |
| | cyclotene | FL/FR |
| | cyclotene hydrate | FL/FR |
| | ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| | ethyl cyclopentenolone | FL/FR |
| | fenugreek absolute | FL/FR |
| | fenugreek oleoresin | FL/FR |
| | geranyl crotonate | FR |
| cis-2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | |
| | maple furanone | FL/FR |
| | menthone lactone | FL/FR |
| 2- | methoxy-3,5-dimethyl-2-cyclopenten-1-one | |
| 5- | methyl furfural | FL/FR |
| | shoyu furanone | FL/FR |
| cheesy |
| 2- | heptanone | FL/FR |
| chocolate |
| | chocolate pyrazine A | FL/FR |
| | cocoa hexenal | FL/FR |
| 2,6- | dimethyl pyrazine | FL/FR |
| 2,5- | dimethyl pyrazine | FL/FR |
| 2- | methoxy-3-methyl pyrazine | FL/FR |
| 2- | methoxypyrazine | FL/FR |
| 2,4,5- | trimethyl thiazole | FL/FR |
| cocoa |
| 2-iso | butyl-3,5-(and 3,6)-dimethyl pyrazine | FL/FR |
| 2- | methyl butyraldehyde | FL/FR |
| coconut |
| alpha- | angelica lactone | FL/FR |
| | coconut decanone methyl | FR |
| | coconut naphthalenone | FL/FR |
| delta- | decalactone | FL/FR |
| delta-2- | dodecenolactone | FL/FR |
| gamma- | heptalactone | FL/FR |
| delta- | heptalactone | FL/FR |
| | hexahydrocoumarin | CS |
| delta- | nonalactone | FL/FR |
| gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| gamma- | octalactone | FL/FR |
| delta- | octalactone | FL/FR |
| | propyl octanoate | FL/FR |
| | tetrahydrojasmone | FR |
| delta- | undecalactone | FL/FR |
| | wine lactone | FL/FR |
| | popcorn pyrimidine | FL/FR |
| coumarinic |
| | coumane | FL/FR |
| | phthalide | FL/FR |
| | tonka bean resinoid | FR |
| creamy |
| | creamy lactone | FL/FR |
| earthy |
| 2- | ethyl-3-methoxypyrazine | FL/FR |
| | nutty pyrazine | FL/FR |
| fatty |
| | coconut absolute | FL/FR |
| | lauric acid | FL/FR |
| (Z)-2- | octenal | |
| fermented |
| | valeraldehyde | FL/FR |
| floral |
| | autumn carboxylate | FR |
| | boronia butenal | FR |
| para- | cresyl laurate | FL/FR |
| | dihydrojasmone lactone | FL/FR |
| | heliotropin | FL/FR |
| | hexenyl cyclopentanone | FR |
| | jasmin lactone (IFF) | FL/FR |
| ortho- | methyl acetophenone | FL/FR |
| 2- | pentyl cyclopentanone | FR |
| 2- | phenyl propionaldehyde dimethyl acetal | FL/FR |
| fruity |
| | allyl 2-ethyl butyrate | FL/FR |
| | amyl heptanoate | FL/FR |
| iso | amyl nonanoate | FL/FR |
| iso | amyl octanoate | FL/FR |
| gamma- | decalactone | FL/FR |
| 4- | hydroxybenzyl alcohol | FL/FR |
| | methyl (Z)-5-octenoate | FL/FR |
| | methyl valerate | FL/FR |
| 3- | methyl-2-butenal | FL/FR |
| | nonyl isovalerate | FL/FR |
| iso | propyl octanoate | FL/FR |
| | tropical thiazole | FL/FR |
| green |
| alpha- | decalactone | FL/FR |
| 2- | heptyl furan | FL/FR |
| (E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| | tiglaldehyde | FL/FR |
| herbal |
| | acorn acetate | FR |
| 3- | propylidene phthalide | FL/FR |
| | saffron pyranone | FR |
| medicinal |
| meta- | dimethyl hydroquinone | FL/FR |
| moldy |
| | strawberry furanone methyl ether | FL/FR |
| musty |
| 2- | acetyl pyrrole | FL/FR |
| 3- | acetyl-2,5-dimethyl furan | FL/FR |
| | hazelnut pyrazine | FL/FR |
| | menthofuran | FL/FR |
| naphthyl |
| para- | methyl anisole | FL/FR |
| ortho- | methyl anisole | FL/FR |
| nutty |
| 3- | acetyl pyridine | FL/FR |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2- | acetyl-3-methyl pyrazine | FL/FR |
| 2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| 2- | acetyl-5-methyl furan | FL/FR |
| 3,6- | cocoa pyrazine | FL/FR |
| 3,5- | cocoa pyrazine | FL/FR |
| 2,3- | dimethyl pyrazine | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2- | ethyl pyrazine | FL/FR |
| 2- | ethyl-4-methyl thiazole | FL/FR |
| | filbert heptenone | FL/FR |
| | filbert pyrazine | FL/FR |
| 2,6- | lutidine | FL/FR |
| | maraniol | CS |
| 2- | methyl pyrazine | FL/FR |
| 5- | methyl quinoxaline | FL/FR |
| 2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| 2- | methyl-3-ethoxypyrazine | FL/FR |
| 2- | methyl-3-pentenoic acid | FL/FR |
| 2- | methyl-3-propyl pyrazine | FL/FR |
| | nutty cyclohexenone | FL/FR |
| | nutty quinoxaline | FL/FR |
| ortho- | salicylic acid | CS |
| | shoyu pyrazine | FL/FR |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| 2,4,5- | trimethyl oxazole | FL/FR |
| 2,3,5- | trimethyl pyrazine | FL/FR |
| | vinyl sulfurol | FL/FR |
| popcorn |
| 2- | acetyl pyrazine | FL/FR |
| 2- | acetyl thiazole | FL/FR |
| roasted |
| 2- | acetyl-2-pyrroline | |
| | fenugreek resinoid | FL/FR |
| soapy |
| | ethyl undecanoate | FL/FR |
| spicy |
| 3-(2- | furyl) acrolein | FL/FR |
| | mace absolute | FL/FR |
| | mace oil | FL/FR |
| | mace oleoresin | FL/FR |
| | methyl heptadienone | FL/FR |
| | nutmeg oil | FL/FR |
| | nutmeg oil CO2 extract | FL/FR |
| | nutmeg oil terpeneless | FL/FR |
| | nutmeg oleoresin | FL/FR |
| | tea tree oil | FR |
| sulfurous |
| | benzothiazole | FL/FR |
| | furfuryl thioacetate | FL/FR |
| sweet |
| 2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | FL/FR |
| terpenic |
| | cassis bud oil | FL/FR |
| tobacco |
| (E,E/E,Z)- | tobacco cyclohexenone | FL/FR |
| | veltonal (Bedoukian) | FR |
| tonka |
| 6- | amyl-alpha-pyrone | FL/FR |
| | coumarin | FR |
| gamma- | hexalactone | FL/FR |
| 7- | methyl coumarin | CS |
| | mint lactone | FL/FR |
| | tonka bean absolute | FR |
| | whiskey lactone | FL/FR |
| tropical |
| delta- | dodecalactone | FL/FR |
| | glyceryl 5-hydroxydecanoate | FL/FR |
| | glyceryl 5-hydroxydodecanoate | FL/FR |
| waxy |
| | butyl laurate | FL/FR |
| 1- | dodecanol | FL/FR |
| | methyl laurate | FL/FR |
| | myristyl alcohol | FL/FR |
| 2- | tridecanone | FL/FR |
| | undecanoic acid | FL/FR |
| woody |
| | cedrenyl acetate | FR |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| | sandalwood oil | FL/FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | acetyl acetaldehyde dimethyl acetal | FL |
| 2- | acetyl-2-pyrroline | |
| (E)- | aconitic acid | FL |
| | bornyl isobutyrate | FL/FR |
| 2-iso | butyl-3,5-(and 3,6)-dimethyl pyrazine | FL/FR |
| 2(4)-iso | butyl-4(2),6-dimethyl dihydro-4H-1,3,5-dithiazine | FL |
| | butyramide | FL |
| | butyrophenone | FL/FR |
| | chocolate pyrazine A | FL/FR |
| | chocolate pyrazine B | FL |
| | coconut naphthalenone | FL/FR |
| | coumane | FL/FR |
| | cyclohexyl methyl pyrazine | FL |
| alpha- | decalactone | FL/FR |
| 2,5- | diethyl thiazole | FL |
| 2,5- | diethyl-4-methyl thiazole | FL |
| 6,7- | dihydro-2,3-dimethyl-5H-cyclopentapyrazine | FL |
| | dimethyl benzofuranone | FL |
| | dimethyl dihydrocyclopentapyrazine | FL |
| 2,5- | dimethyl thiazole | FL |
| 4,5- | dimethyl-2-ethyl thiazole | FL |
| delta-2- | dodecenolactone | FL/FR |
| | ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| 2- | ethyl-3-methoxypyrazine | FL/FR |
| (Z+E)-5- | ethyl-4-methyl-2-(2-butyl) thiazoline | FL |
| (Z+E)-5- | ethyl-4-methyl-2-(2-methyl propyl) thiazoline | FL |
| 3-(2- | furyl) acrolein | FL/FR |
| (E,E)-2,4- | heptadien-1-ol | FL |
| 2- | hexyl-5 or 6-keto-1,4-dioxane | FL |
| 2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | FL/FR |
| cis-2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | |
| | jasmin lactone (IFF) | FL/FR |
| | lauric acid | FL/FR |
| | menthone lactone | FL/FR |
| 2- | methoxy-3,5-dimethyl-2-cyclopenten-1-one | |
| 2- | methoxypyrazine | FL/FR |
| | methyl 2-(methyl thio) acetate | FL |
| 2- | methyl-3-(methyl thio) pyrazine | FL/FR |
| 2- | methyl-3-ethoxypyrazine | FL/FR |
| 2- | methyl-3-pentenoic acid | FL/FR |
| | myristyl alcohol | FL/FR |
| | nonyl isovalerate | FL/FR |
| 4- | octen-3-one | FL |
| (Z)-2- | octenal | |
| | peanut dithiazine | FL |
| | propyl octanoate | FL/FR |
| 2- | propyl pyridine | FL |
| | pyrazine | FL |
| | pyrazines mixture | FL |
| | pyrrole | FL |
| para- | salicylic acid | FL |
| | sulfuryl butyrate | FL/FR |
| | sulfuryl decanoate | FL/FR |
| | sulfuryl hexanoate | FL/FR |
| | sulfuryl isobutyrate | FL/FR |
| | thiazole | FL |
| (R)- | tonka furanone | FL |
| | valeraldehyde propylene glycol acetal | FL/FR |
| | wine lactone | FL/FR |
|
| 5- | acetyl-2,3-dihydro-1,4-thiazine | FL |
| | sulfuryl formate | FL |
| | sulfuryl octanoate | FL/FR |
| | sulfuryl propionate | FL/FR |
| | valeraldehyde dibutyl acetal | FL/FR |
| alliaceous |
| | dicyclohexyl disulfide | FL |
| 2- | methyl thioacetaldehyde | FL |
| | tropical thiazole | FL/FR |
| anisic |
| ortho- | methyl acetophenone | FL/FR |
| bready |
| 2- | propionyl thiazole | FL |
| brown |
| | fenugreek oleoresin | FL/FR |
| 5- | methyl furfural | FL/FR |
| burnt |
| 2- | methyl quinoxaline | FL |
| 2,4,5- | trimethyl oxazole | FL/FR |
| buttery |
| | butyroin | FL |
| 3,4- | hexane dione | FL/FR |
| camphoreous |
| ortho- | methyl anisole | FL/FR |
| caramellic |
| | caramel dione | FL |
| | caramel furanone | FL |
| | caramel furanone solution | FL/FR |
| | caramel pentadione | FL/FR |
| | cyclotene | FL/FR |
| | cyclotene hydrate | FL/FR |
| | fenugreek absolute | FL/FR |
| | fenugreek resinoid | FL/FR |
| | maple furanone | FL/FR |
| | shoyu furanone | FL/FR |
| cheesy |
| 2- | heptanone | FL/FR |
| chemical |
| meta- | dimethyl hydroquinone | FL/FR |
| cherry |
| | heliotropin | FL/FR |
| cocoa |
| | cocoa hexenal | FL/FR |
| coconut |
| delta- | decalactone | FL/FR |
| (R)- | massoia lactone | FL |
| 6- | methyl coumarin | FL |
| gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| delta- | octalactone | FL/FR |
| coffee |
| | difurfuryl ether | FL |
| 2- | ethyl-4-methyl thiazole | FL/FR |
| 2-iso | propyl pyrazine | FL |
| corn chip |
| 2- | acetyl thiazole | FL/FR |
| 2- | acetyl-2-thiazoline | FL |
| | popcorn pyrimidine | FL/FR |
| coumarinic |
| | phthalide | FL/FR |
| creamy |
| 6- | amyl-alpha-pyrone | FL/FR |
| alpha- | angelica lactone | FL/FR |
| | creamy lactone | FL/FR |
| 5,5- | dibutyl dihydrofuran-2(3H)-one | FL |
| delta- | dodecalactone | FL/FR |
| | glyceryl 5-hydroxydecanoate | FL/FR |
| | glyceryl 5-hydroxydodecanoate | FL/FR |
| gamma- | hexalactone | FL/FR |
| | mint lactone | FL/FR |
| delta- | nonalactone | FL/FR |
| delta- | undecalactone | FL/FR |
| dairy |
| | methyl (Z)-5-octenoate | FL/FR |
| earthy |
| 2- | methyl-3-propyl pyrazine | FL/FR |
| ethereal |
| | allyl 2-ethyl butyrate | FL/FR |
| fatty |
| | coconut absolute | FL/FR |
| (E,E)-2,4- | decadienal | FL |
| 2- | heptyl furan | FL/FR |
| (E,E)-2,4- | nonadienal | FL |
| 2- | tridecanone | FL/FR |
| fishy |
| 4,5- | dimethyl thiazole | FL |
| fruity |
| | amyl heptanoate | FL/FR |
| iso | amyl octanoate | FL/FR |
| | cassis bud oil | FL/FR |
| gamma- | decalactone | FL/FR |
| 2,4- | hexadien-1-ol | FL |
| 4- | hydroxybenzyl alcohol | FL/FR |
| | methyl valerate | FL/FR |
| 3- | methyl-2-butenal | FL/FR |
| 2- | phenyl propionaldehyde dimethyl acetal | FL/FR |
| | propyl benzoate | FL/FR |
| iso | propyl octanoate | FL/FR |
| | terpinyl cinnamate | FL/FR |
| | tiglaldehyde | FL/FR |
| fusel |
| 2- | methyl butyraldehyde | FL/FR |
| green |
| | dihydroxyacetophenone (mixed isomers) | FL |
| 2,5- | dimethyl thiophene | FL |
| | methyl heptadienone | FL/FR |
| 4- | methyl thiazole | FL |
| 2- | methyl-5-isopropyl pyrazine | FL |
| (E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| 3- | propylidene phthalide | FL/FR |
| 2- | vinyl pyrazine | FL |
| herbal |
| | massoia bark oil | FL |
| jammy |
| | ethyl cyclopentenolone | FL/FR |
| lactonic |
| delta- | heptalactone | FL/FR |
| gamma- | heptalactone | FL/FR |
| gamma- | octalactone | FL/FR |
| meaty |
| | benzothiazole | FL/FR |
| 2,6- | dimethyl pyrazine | FL/FR |
| moldy |
| | strawberry furanone methyl ether | FL/FR |
| musty |
| 2,5- | dimethyl pyrazine | FL/FR |
| 2- | ethoxythiazole | FL |
| | hazelnut pyrazine | FL/FR |
| | menthofuran | FL/FR |
| | propionaldehyde | FL |
| | shoyu pyrazine | FL/FR |
| 2,3,5- | trimethyl pyrazine | FL/FR |
| naphthyl |
| para- | methyl anisole | FL/FR |
| nutty |
| 3- | acetyl pyridine | FL/FR |
| 2- | acetyl pyrrole | FL/FR |
| 3- | acetyl-2,5-dimethyl furan | FL/FR |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2- | acetyl-3-methyl pyrazine | FL/FR |
| 2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| 2- | acetyl-5-methyl furan | FL/FR |
| | aconitic acid | FL |
| 3,5- | cocoa pyrazine | FL/FR |
| 3,6- | cocoa pyrazine | FL/FR |
| | coffee furanone | FL/FR |
| 3,5- | diethyl-2-methyl pyrazine | FL |
| 2,5- | diethyl-3-methyl pyrazine | FL |
| 2,3- | dimethyl pyrazine | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2,4- | dimethyl-5-vinyl thiazole | FL |
| 2- | ethyl pyrazine | FL/FR |
| 1- | ethyl-2-acetyl pyrrole | FL |
| | filbert heptenone | FL/FR |
| | filbert pyrazine | FL/FR |
| european | hazelnut oleoresin | FL |
| 2,6- | lutidine | FL/FR |
| 2- | methoxy-3-methyl pyrazine | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| 5- | methyl quinoxaline | FL/FR |
| 2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| | nutty cyclohexenone | FL/FR |
| | nutty pyrazine | FL/FR |
| | nutty quinoxaline | FL/FR |
| | nutty thiazole | FL |
| | peanut oxazole | FL |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| (E,E/E,Z)- | tobacco cyclohexenone | FL/FR |
| 2,4,5- | trimethyl thiazole | FL/FR |
| | vinyl sulfurol | FL/FR |
| popcorn |
| 2- | propionyl-2-thiazoline | FL |
| roasted |
| 2- | acetyl pyrazine | FL/FR |
| | furfuryl thioacetate | FL/FR |
| smoky |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| soapy |
| 1- | dodecanol | FL/FR |
| spicy |
| | mace absolute | FL/FR |
| | mace oil | FL/FR |
| | mace oleoresin | FL/FR |
| | nutmeg oil | FL/FR |
| | nutmeg oil CO2 extract | FL/FR |
| | nutmeg oil terpeneless | FL/FR |
| | nutmeg oleoresin | FL/FR |
| toasted |
| | acetyl propionyl | FL/FR |
| waxy |
| | butyl laurate | FL/FR |
| para- | cresyl laurate | FL/FR |
| | dihydrojasmone lactone | FL/FR |
| | ethyl undecanoate | FL/FR |
| | methyl laurate | FL/FR |
| | undecanoic acid | FL/FR |
| winey |
| iso | amyl nonanoate | FL/FR |
| 5- | ethyl-2-methyl pyridine | FL |
| | valeraldehyde | FL/FR |
| | sandalwood oil | FL/FR |
| | whiskey lactone | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,2- | cyclohexadione | | | cyclohexan-1,2-dione | | | cyclohexane-1,2-dione | | 1,2- | cyclohexanedione | | 1,2- | dioxocyclohexane |
Articles:
| PubMed: | Extended Reaction Scope of Thiamine Diphosphate Dependent Cyclohexane-1,2-dione Hydrolase: From CC Bond Cleavage to CC Bond Ligation. |
| PubMed: | Microwave Measurements of the Spectra and Molecular Structure for the Monoenolic Tautomer of 1,2- Cyclohexanedione. |
| PubMed: | Catalytic scope of the thiamine-dependent multifunctional enzyme cyclohexane-1,2-dione hydrolase. |
| PubMed: | Irreversible inactivation of snake venom l-amino acid oxidase by covalent modification during catalysis of l-propargylglycine. |
| PubMed: | Phylogenetic analysis, molecular modeling, substrate-inhibitor specificity, and active site comparison of bacterial, fungal, and plant heme peroxidases. |
| PubMed: | Photodissociation dynamics of enolic 1,2-cyclohexanedione at 266, 248, and 193 nm: mechanism and nascent state product distribution of OH. |
| PubMed: | Regulation of connexin36 gap junction channels by n-alkanols and arachidonic acid. |
| PubMed: | In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons. |
| PubMed: | Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family. |
| PubMed: | Cyclohexane-1,2-dione hydrolase from denitrifying Azoarcus sp. strain 22Lin, a novel member of the thiamine diphosphate enzyme family. |
| PubMed: | Colorimetric filtrations of metal chelate precipitations for the quantitative determination of nickel(II) and lead(II). |
| PubMed: | Theoretical study of oxidation of cyclohexane diol to adipic anhydride by [Ru(IV)(O)(tpa)(H2O)]2+ complex (tpa ═ tris(2-pyridylmethyl)amine). |
| PubMed: | Organocatalyzed synthesis of 2-amino-8-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitriles. |
| PubMed: | Cooperative strengthening of an intramolecular O-H...O hydrogen bond by a weak C-H...O counterpart: matrix-isolation infrared spectroscopy and quantum chemical studies on 3-methyl-1,2-cyclohexanedione. |
| PubMed: | Electron transfer as a potential cause of diacetyl toxicity in popcorn lung disease. |
| PubMed: | Arginine, a key residue for the enhancing ability of an antifreeze protein of the beetle Dendroides canadensis. |
| PubMed: | Catalytic adsorptive stripping voltammetry versus electrothermal atomic absorption spectrometry in the determination of trace cobalt and chromium in human urine. |
| PubMed: | Total synthesis of the strychnos alkaloid (+)-minfiensine: tandem enantioselective intramolecular Heck-iminium ion cyclization. |
| PubMed: | Cationic rhodium(I)/segphos-catalyzed cycloisomerization of 1,6- and 1,7-diynes in the presence of 1,2-cyclohexanedione. |
| PubMed: | AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis. |
| PubMed: | Semiconductor surface-induced 1,3-hydrogen shift: the role of covalent vs zwitterionic character. |
| PubMed: | Novel biscapped and monocapped tris(dioxime) Mn(II) complexes: x-ray crystal structure of the first cationic tris(dioxime) Mn(II) complex [Mn(CDOH)3BPh]OH (CDOH2= 1,2-cyclohexanedione dioxime). |
| PubMed: | Reduction of activated carbonyl groups by alkyl phosphines: formation of alpha-hydroxy esters and ketones. |
| PubMed: | Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2. |
| PubMed: | Synthesis of new dihydropyrazines with DNA strand-breakage activity. |
| PubMed: | Structure-sweetness relationship in egg white lysozyme: role of lysine and arginine residues on the elicitation of lysozyme sweetness. |
| PubMed: | Sequential catalytic asymmetric Heck-iminium ion cyclization: enantioselective total synthesis of the Strychnos alkaloid minfiensine. |
| PubMed: | A one-pot isomerization-arylation of 2,3-epoxycyclohexanone under controlled microwave heating. |
| PubMed: | Streptavidin in antibody pretargeting. 4. Site-directed mutation provides evidence that both arginine and lysine residues are involved in kidney localization. |
| PubMed: | Chemical modification of arginine residues of Notechis scutatus scutatus notexin. |
| PubMed: | Solid-phase fluoroimmunoassay for the determination of mesotrione--a novel triketone herbicide--in water with direct measurement of the fluorescence onto the solid support. |
| PubMed: | Synthesis of eight- and nine-membered carbocycles through a ring-closing metathesis/ring fragmentation strategy: a rapid and versatile approach to bicyclo[6.4.0]- and bicyclo[7.4.0]alkene ring systems. |
| PubMed: | Oxidative cleavage of the C-C bond of 3,6-dialkylcyclohexane-1,2-diones by cell suspension cultures of Marchantia polymorpha. |
| PubMed: | Effects of modifications of alpha-crystallin on its chaperone and other properties. |
| PubMed: | Streptavidin in antibody pretargeting. 3. Comparison of biotin binding and tissue localization of 1,2-cyclohexanedione and succinic anhydride modified recombinant streptavidin. |
| PubMed: | Intercalation of multiple carbon atoms between the carbonyls of alpha-diketones. |
| PubMed: | Evidence for an essential arginine in the flavoprotein nitroalkane oxidase. |
| PubMed: | Isolation and initial characterization of 13(2)-hydroxychlorophyll a induced by cyclohexanedione derivatives in tobacco cell suspension cultures. |
| PubMed: | Chemical modification of xylanase from Trichosporon cutaneum shows the presence of carboxyl groups and cysteine residues essential for enzyme activity. |
| PubMed: | Characterisation of the conformational and quaternary structure-dependent heparin-binding region of bovine seminal plasma protein PDC-109. |
| PubMed: | Myo-inositol hexasulfate is a potent inhibitor of Aspergillus ficuum phytase. |
| PubMed: | Identification of arg-30 as the essential residue for the enzymatic activity of Taiwan cobra phospholipase A2. |
| PubMed: | Glucose transport inhibitors protect against 1,2-cyclohexanedione-produced potassium loss from human red blood cells. |
| PubMed: | The effect of ATP-depletion on the inhibition of glucose exits from human red cells. |
| PubMed: | Differences in the active site environment of Aspergillus ficuum phytases. |
| PubMed: | Effect of the chemical modification of the arginyl residue in Bombyx mori silk fibroin on the attachment and growth of fibroblast cells. |
| PubMed: | Modification of arginine-198 in sarcoplasmic reticulum Ca2+-ATPase by 1,2-cyclohexanedione causes inhibition of formation of the phosphoenzyme intermediate from inorganic phosphate. |
| PubMed: | A Versatile Route to Substituted 1,4-Diazine-Fused [60]Fullerenes. |
| PubMed: | Determination of cobalt in seawater by catalytic adsorptive cathodic stripping voltammetry. |
| PubMed: | Identification of arginyl residues located at the ATP binding site of sarcoplasmic reticulum Ca2+-ATPase. Modification with 1,2-cyclohexanedione. |
| PubMed: | trans,anti,trans-Tetra(spirotetrahydrofuranyl)cyclohexane-1,2-dione. Stereocontrolled Synthesis and Definition of Its Susceptibility to Photoisomerization. |
| PubMed: | Comparison of the gas-phase basicities and relative methylation nucleophilicities of carbonyl-containing compounds. |
| PubMed: | Chemical modification of the arginyl residue in silk fibroin: 2. Reaction of 1,2-cyclohexanedione in aqueous alkaline medium. |
| PubMed: | Outer-Sphere Electron Transfer in Methylene Chloride: Concentration, Salt, and Temperature Dependences of the Oxidation of beta-Re(2)X(4)(cis-1,2-bis(diphenylphosphino)ethylene)(2) (X = Cl, Br) by [Co(dimethylglyoximate)(3)(BF)(2)]BF(4) and the Oxidation of Re(2)Br(4)(PMe(2)Ph)(4) by [Co(1,2-cyclohexanedione dioximate)(3)(BBu)(2)]BF(4). |
| PubMed: | Albumin stimulates uptake of calcium into subcellular stores in rat cortical astrocytes. |
| PubMed: | Probing the active site residues in aromatic donor oxidation in horseradish peroxidase: involvement of an arginine and a tyrosine residue in aromatic donor binding. |
| PubMed: | Albumin reduces basement membrane hydraulic conductance in part due to arginyl side groups. |
| PubMed: | Lysosomal sulfate transport: inhibitor studies. |
| PubMed: | Role of arginine residues for the activity of fasciculin. |
| PubMed: | Chemical modification of cationic groups in the polypeptide cardiac stimulant anthopleurin-A. |
| PubMed: | High-yield production of human big endothelin-1 by a combination of chemical modification and proteolysis of a fusion protein in Escherichia coli. |
| PubMed: | Modification of arginine residues in ovine prolactin by 1,2-cyclohexanedione. Effect on binding capacity to lactogenic receptors. |
| PubMed: | Lactoferrin inhibits cholesterol accumulation in macrophages mediated by acetylated or oxidized low-density lipoproteins. |
| PubMed: | Probing the function(s) of active-site arginine residue in Leishmania donovani adenosine kinase. |
| PubMed: | Differential sensitivity to Arg side chain modification of IL-1 beta binding to type I and type II receptors. |
| PubMed: | Correlations between chemical reactivity and mutagenic activity against S. typhimurium TA100 for alpha-dicarbonyl compounds as a proof of the mutagenic mechanism. |
| PubMed: | Removal of 14 N-terminal amino acids of lactoferrin enhances its affinity for parenchymal liver cells and potentiates the inhibition of beta- very low density lipoprotein binding. |
| PubMed: | Lipases from Rhizomucor miehei and Humicola lanuginosa: modification of the lid covering the active site alters enantioselectivity. |
| PubMed: | The role of arginines in stabilizing the active open-lid conformation of Rhizomucor miehei lipase. |
| PubMed: | Arginine residues of the globular regions of human C1q involved in the interaction with immunoglobulin G. |
| PubMed: | Fenofibrate and LDL metabolic heterogeneity in hypercholesterolemia. |
| PubMed: | Stimulation of bovine brain phospholipase C activity by myelin basic protein requires arginyl residues in peptide linkage. |
| PubMed: | Binding of a synthetic apolipoprotein B-100 peptide and peptide analogues to chondroitin 6-sulfate: effects of the lipid environment. |
| PubMed: | Inactivation of Escherichia coli 2-amino-3-ketobutyrate CoA ligase by phenylglyoxal and identification of an active-site arginine peptide. |
| PubMed: | Chemical modification of arginine residues in alpha-bungarotoxin. |
| PubMed: | A contribution to the study of the structure-mutagenicity relationship for alpha-dicarbonyl compounds using the Ames test. |
| PubMed: | Chemical modification of arginyl residues in silk fibroin: 1. Reaction of 1,2-cyclohexanedione in borate buffer. |
| PubMed: | Protein surface topology-probing by selective chemical modification and mass spectrometric peptide mapping. |
| PubMed: | Lactoferrin uptake by the rat liver. Characterization of the recognition site and effect of selective modification of arginine residues. |
| PubMed: | Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase. |
| PubMed: | Plasma triglyceride and low density lipoprotein metabolism. |
| PubMed: | Cyclohexanedione modification of arginine at the active site of Aspergillus ficuum phytase. |
| PubMed: | Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol. |
| PubMed: | Interaction of fibronectin with heparin in model extracellular matrices: role of arginine residues and sulfate groups. |
| PubMed: | Arginyl residues in the NADPH-binding sites of phenol hydroxylase. |
| PubMed: | Chemical modification and NMR studies on a mushroom lectin Ischnoderma resinosum agglutinin (IRA). |
| PubMed: | Binding of locust high-density lipophorin to fat body proteins monitored by an enzyme-linked immunosorbant assay. |
| PubMed: | Tryptophan 65 is essential for hemolytic activity of the thermostable direct hemolysin from Vibrio parahaemolyticus. |
| PubMed: | Fast atom bombardment mass spectrometric analysis of arginine-containing neuropeptides. |
| PubMed: | Essential arginine residues in the nitrate uptake system from corn seedling roots. |
| PubMed: | Evidence for the importance of a carboxyl group in the binding of ligands to the D2 dopamine receptor. |
| PubMed: | Modification of arginine residues in human growth hormone by 1,2-cyclohexanedione: effects on the binding capacity to lactogenic and somatogenic receptors. |
| PubMed: | Chemical modification by pyridoxal 5'-phosphate and cyclohexane-1,2-dione indicates that Lys-7 and Arg-10 are involved in the p2 phosphate-binding subsite of bovine pancreatic ribonuclease A. |
| PubMed: | Purification and properties of two oxidoreductases catalyzing the enantioselective reduction of diacetyl and other diketones from baker's yeast. |
| PubMed: | Resonance Raman spectroscopy of chemically modified hemoglobins. |
| PubMed: | Inhibition of Clostridium difficile toxin A and B by 1,2-cyclohexanedione modification of an arginine residue. |
| PubMed: | Study of the role of tryptophanyl and arginyl residues in the specific binding of 3,5,3'-triiodothyronine to rat liver nuclear receptors. |
| PubMed: | Role of albumin arginyl sites in albumin-induced reduction of endothelial hydraulic conductivity. |
| PubMed: | Inactivation of Escherichia coli L-threonine dehydrogenase by 2,3-butanedione. Evidence for a catalytically essential arginine residue. |
| PubMed: | A neutral technetium-99m complex for myocardial imaging. |
| PubMed: | Identification of essential arginine residue(s) for Mg-ATP binding of human argininosuccinate synthetase. |
| PubMed: | Protection of hexaprenyl-diphosphate synthase of Micrococcus luteus B-P 26 against inactivation by sulphydryl reagents and arginine-specific reagents. |
| PubMed: | Arginine residues at the active site of avian liver phosphoenolpyruvate carboxykinase. |
| PubMed: | Complete amino acid sequence of the sarcoplasmic calcium-binding protein (SCP-I) from crayfish (Astacus leptodactylus). |
| PubMed: | Uptake and release of two new Tc-99m labeled myocardial blood flow imaging agents in cultured cardiac cells. |
| PubMed: | Modification of arginine in sea anemone toxin RTX-III from Radianthus macrodactylus. |
| PubMed: | Effect of 2,3-butanedione on human myeloperoxidase. |
| PubMed: | On the receptor binding site of relaxins. |
| PubMed: | The secondary structure of apolipoproteins in human HDL3 particles after chemical modification of their tyrosine, lysine, cysteine or arginine residues. A Fourier transform infrared spectroscopy study. |
| PubMed: | The action of arginine-specific reagents on ionic and gating currents in frog myelinated nerve. |
| PubMed: | The oxidation-state-dependent ATP-binding site of cytochrome c. Implication of an essential arginine residue and the effect of occupancy on the oxidation-reduction potential. |
| PubMed: | Involvement of arginine residues in the activation of calmodulin-dependent 3',5'-cyclic-nucleotide phosphodiesterase. |
| PubMed: | 1,2-Cyclohexanedione modification of arginine residues in egg-white riboflavin-binding protein. |
| PubMed: | Stimulation of the erythrocyte Ca2+-ATPase and of bovine brain cyclic nucleotide phosphodiesterase by chemically modified calmodulin. |
| PubMed: | Inhibition of staphylococcal alpha-toxin by covalent modification of an arginine residue. |
| PubMed: | Chemical modification studies on a lectin from Saccharomyces cerevisiae (baker's yeast). |
| PubMed: | Stimulation of mast cells leads to cholesterol accumulation in macrophages in vitro by a mast cell granule-mediated uptake of low density lipoprotein. |
| PubMed: | Protein inhibitors of trypsin from the seeds of Cucurbitaceae plants. |
| PubMed: | Molecular mechanisms of band 3 inhibitors. 2. Channel blockers. |
| PubMed: | Correlation of structural changes in parathyroid hormone with its vascular action. |
| PubMed: | Inhibition of the mitochondrial tricarboxylate carrier by arginine-specific reagents. |
| PubMed: | Involvement of arginine residues in inhibition of protein synthesis by ricin A-chain. |
| PubMed: | Amino acid residues complexed with eosin 5-isothiocyanate in band 3 protein of the human erythrocyte. |
| PubMed: | Insulin regulates low density lipoprotein metabolism by swine granulosa cells. |
| PubMed: | Novobiocin precipitates histones at concentrations normally used to inhibit eukaryotic type II topoisomerase. |
| PubMed: | UDP-glucose 4-epimerase from Saccharomyces fragilis. Presence of an essential arginine residue at the substrate-binding site of the enzyme. |
| PubMed: | Chemical modification of lysine and arginine residues in the myosin regulatory light chain inhibits phosphorylation. |
| PubMed: | Differential effects of defined chemical modifications on antigenic and pharmacological activities of scorpion alpha and beta toxins. |
| PubMed: | Synthesis and characterization of 1,2-cyclohexanedione bis-benzoyl-hydrazone and its application to the determination of ti in minerals and rocks. |
| PubMed: | Receptor-independent low-density lipoprotein catabolism. |
| PubMed: | The role of lysyl, arginyl, and sulfhydryl residues in estrogen receptor activation, 4S to 5S dimerization, and conversion of receptor from a state with low affinity into a state with higher affinity for estrogen. |
| PubMed: | Chemical modification of arginine residues of lung galaptin and fibronectin. Effects on fibroblast binding. |
| PubMed: | Evidence for arginine residues in the immunoglobulin-binding sites of human Clq. |
| PubMed: | Effects of 1,2-cyclohexanedione modification on the metabolism of very low density lipoprotein apolipoprotein B: potential role of receptors in intermediate density lipoprotein catabolism. |
| PubMed: | Properties of low density lipoprotein binding by cultured swine granulosa cells. |
| PubMed: | Phosphoenolpyruvate-dependent phosphotransferase system. 1H NMR studies on chemically modified HPr proteins. |
| PubMed: | C1q binding to mitochondria: a possible artefact? |
| PubMed: | Evidence for an essential arginine residue in the active site of Escherichia coli 2-keto-4-hydroxyglutarate aldolase. Modification with 1,2-cyclohexanedione. |
| PubMed: | The effects of native and modified bovine serum albumin on the permeability of frog mesenteric capillaries. |
| PubMed: | L-Lactate dehydrogenase from Thermus caldophilus GK24, an extremely thermophilic bacterium. Desensitization to fructose 1,6-bisphosphate in the activated state by arginine-specific chemical modification and the N-terminal amino acid sequence. |
| PubMed: | Functional implication of the sole arginine residue of ribosomal proteins L7/L12. |
| PubMed: | The fibrin-binding site of human plasminogen. Arginines 32 and 34 are essential for fibrin affinity of the kringle 1 domain. |
| PubMed: | Isolation and characterization of trypsin inhibitors from tubers of taro, Colocasia antiquorum var. nymphaifolia? |
| PubMed: | Contribution of the receptor pathway to low density lipoprotein catabolism in humans. New methods for quantitation. |
| PubMed: | Modification of apolipoprotein C-II with 1,2-cyclohexanedione and 2,3-butanedione. Role of arginine in the activation of lipoprotein lipase. |
| PubMed: | In vivo characteristics of a specific recognition site for LDL on non-parenchymal rat liver cells which differs from the 17 alpha-ethinyl estradiol-induced LDL receptor on parenchymal liver cells. |
| PubMed: | Partial purification and characterization of the soluble phosphatidate phosphohydrolase of rat liver. |
| PubMed: | Retention of apolipoprotein B and cholesterol by perfused heart during lipolysis of very-low-density lipoprotein. |
| PubMed: | Arginine modification in elastase. Effect on catalytic activity and conformation of the calcium-binding site. |
| PubMed: | Differential effect of arginine modification with 1,2-cyclohexanedione on the capacity of vimentin and desmin to assemble into intermediate filaments and to bind to nucleic acids. |
| PubMed: | Basic and acidic hydrophilic residues involved in the interaction between protomers of the bovine growth hormone dimer. |
| PubMed: | The semisynthesis of analogues of cytochrome c. Modifications of arginine residues 38 and 91. |
| PubMed: | Modification of arginines in D-beta-hydroxybutyrate dehydrogenase. |
| PubMed: | Synthesis of [1-14C]1,2-cyclohexanedione bis(4-diethylenoxythiosemicarbazone) and preliminary biodistribution studies of this potential antitumor agent. |
| PubMed: | Photochemical inactivation of human placental estradiol 17 beta-dehydrogenase in the presence of 2,3-butanedione. |
| PubMed: | Modification of arginines in bovine growth hormone. |
| PubMed: | [Role of arginine and histidine residues in the biological activity of botulinic neurotoxin A]. |
| PubMed: | The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments. |
| PubMed: | The role of arginyl residues in estrogen receptor activation and transformation. |
| PubMed: | Completion of the amino acid sequence of the alpha 1 chain from type I calf skin collagen. Amino acid sequence of alpha 1(I)B8. |
| PubMed: | Cholesterol feeding increases low density lipoprotein synthesis. |
| PubMed: | Studies on the role of specific cell surface receptors in the removal of lipoprotein (a) in man. |
| PubMed: | An exploration of the binding site of aldolase using alkanediol monoglycolate bisphosphoric esters. |
| PubMed: | Modification of arginine residues in phoratoxin B by 1,2-cyclohexanedione. |
| PubMed: | Preparation and characteristics of trypsin inhibitors from the seeds of squash (Cucurbita maxima) and zucchini (Cucurbita pepo var. Giromontia). |
| PubMed: | Oligodeoxynucleotide base recognition by steroid hormone receptors. |
| PubMed: | Isolation and characterization of a specific enterokinase inhibitor from kidney bean (Phaseolus vulgaris). |
| PubMed: | Metabolism of glycerate-2,3-P2-III. Arginine-specific reagents inactivate the phosphoglycerate mutase, glycerate-2,3-P2 synthase and glycerate-2,3-P2 phosphatase activities of rabbit muscle phosphoglycerate mutase. |
| PubMed: | Calmodulin antagonists' binding sites on calmodulin. |
| PubMed: | Botulinum neurotoxin type E: studies on mechanism of action and on structure-activity relationships. |
| PubMed: | Modification of an arginine residue in pig kidney general acyl-coenzyme A dehydrogenase by cyclohexane-1,2-dione. |
| PubMed: | Arginyl residues of adrenodoxin reductase as the anion recognition site for 2'-phosphate group of NADP+1. |
| PubMed: | Receptor-mediated catabolism and tissue uptake of human low density lipoprotein in the cholesterol-fed, atherosclerotic rabbit. |
| PubMed: | Tryptic peptide analysis of the human apolipoprotein E isomorphs. |
| PubMed: | Heat stability of milk: influence of modification of lysine and arginine on the heat stability-pH profile. |
| PubMed: | Inhibition of the binding of dexamethasone to mammary cytoplasmic glucocorticoid receptor by phenylglyoxal. |
| PubMed: | Inducible macrophage cytotoxins. II. Tumor lysis mechanism involving target cell-binding proteases. |
| PubMed: | Difference in saturable binding of low density lipoprotein to liver membranes from normocholesterolemic subjects and patients with heterozygous familial hypercholesterolemia. |
| PubMed: | Comparative titration of arginyl residues in purified D-beta-hydroxybutyrate apodehydrogenase and in the reconstituted phospholipid-enzyme complex. |
| PubMed: | Activation of erythrocyte Ca2+-plus-Mg2+-stimulated adenosine triphosphatase by protein kinase (cyclic AMP-dependent) inhibitor. Comparison with calmodulin. |
| PubMed: | Interaction of C1q with DNA. |
| PubMed: | Effects of bezafibrate on receptor-mediated and receptor-independent low density lipoprotein catabolism in type II hyperlipoproteinaemic subjects. |
| PubMed: | Chemical modification studies on Ricinus communis (Castor Bean) agglutinin. |
| PubMed: | The effects of modifications of lysyl and arginyl groups on the biological and immunological activity of human chorionic gonadotropin. |
| PubMed: | The reticuloendothelial system and low density lipoprotein metabolism in the rabbit. |
| PubMed: | Permeability of inner mitochondrial membrane to arginine reagents. |
| PubMed: | Formation of complement subcomponent C1q-immunoglobulin G complex. Thermodynamic and chemical-modification studies. |
| PubMed: | Specificity of the Westerfeld adaptation of the Voges-Proskauer test. |
| PubMed: | Chemical modification or excision of neurophysin arginine-8 is associated with loss of peptide-binding ability. |
| PubMed: | Involvement of arginine residues in the allosteric activation of Escherichia coli ADP-glucose synthetase. |
| PubMed: | A critical arginine residue in cytosolic aspartate aminotransferase from pig heart. |
| PubMed: | Location of the intermediate and high affinity omega-aminocarboxylic acid-binding sites in human plasminogen. |
| PubMed: | Essential arginine residues in the pyridine nucleotide binding sites of glutathione reductase. |
| PubMed: | Degradation by cultured fibroblasts and macrophages of unmodified and 1,2-cyclohexanedione-modified low-density lipoprotein from normal and homozygous familial hypercholesterolaemic subjects. |
| PubMed: | Receptor-independent catabolism of low density lipoprotein. Involvement of the reticuloendothelial system. |
| PubMed: | The effect of partial ileal bypass on receptor-mediated uptake and catabolism of low density lipoprotein in the rhesus monkey. |
| PubMed: | Measurement of receptor-independent lipoprotein catabolism using 1,2 cyclohexanedione-modified low density lipoprotein. |
| PubMed: | Primary structure of phycocyanin from the unicellular rhodophyte Cyanidium caldarium. I. Complete amino acid sequence of the alpha subunit. |
| PubMed: | Studies on the chemical modification and potato (Solanum tuberosum) lectin and its effect on haemagglutinating activity. |
| PubMed: | The effect of selective modification of the arginyl residues of partially-metabolized very low density lipoproteins on their uptake by the liver. |
| PubMed: | Chemical modifications of Serratia marcescens anthranilate synthase component I. |
| PubMed: | Reactivity of D-amino acid oxidase with 1,2-cyclohexanedione: evidence for one arginine in the substrate-binding site. |
| PubMed: | Reduced immunoregulatory potency of low density lipoproteins with selectively modified arginine and lysine residues of apolipoprotein B. |
| PubMed: | The complete amino acid sequence of mitochondrial glutamic oxaloacetic transaminase from rat liver. |
| PubMed: | Binding of plasma low density lipoproteins to erythrocytes. |
| PubMed: | Structure-function relationships of sea anemone toxin II from Anemonia sulcata. |
| PubMed: | Modification of arginine residues in porcine pancreatic phospholipase A2. |
| PubMed: | Inhibition of anion transport across red blood cells with 1,2-cyclohexanedione. |
| PubMed: | Chemical modification of critical catalytic residues of lysine, arginine, and tryptophan in human glucose phosphate isomerase. |
| PubMed: | Natural plant enzyme inhibitors. Characterization of an unusual alpha-amylase/trypsin inhibitor from ragi (Eleusine coracana Geartn.). |
| PubMed: | Chemical studies of tissue polypeptide antigen (TPA). III. on the nature of the antigenic determinant(s) of TPA subfraction B1. |
| PubMed: | Effects of cholestyramine on receptor-mediated plasma clearance and tissue uptake of human low density lipoproteins in the rabbit. |
| PubMed: | Presence of an essential arginyl residue in D-beta-hydroxybutyrate dehydrogenase from mitochondrial inner membrane. |
| PubMed: | Complete amino acid sequence of the major component myoglobin from the goose-beaked whale, Ziphius cavirostris. |
| PubMed: | Chemical modifications of Achromobacter collagenase and their influence on the enzymic activity. |
| PubMed: | An essential arginine residue in porcine phospholipiase A2. |
| PubMed: | Studies on the cosubstrate site of protease solubilized NADPH-cytochrome P450 reductase. |
| PubMed: | Further studies of the thylakoid membrane surface charges by particle electrophoresis. |
| PubMed: | Reversible modification of arginine residues in neocarzinostatin. Isolation of a biologically active 89-residue fragment from the tryptic hydrolysate. |
| PubMed: | Origin of the selectivity of alpha-dicarbonyl reagents for arginyl residues of anion-binding sites. |
| PubMed: | Role of arginine residues in the structure and biological activity of botulinum neurotoxin types A and E. |
| PubMed: | Inactivation of adenylate cyclase by phenylglyoxal and other dicarbonyls. Evidence for existence of essential arginyl residues. |
| PubMed: | Inhibition of receptor-mediated clearance of lysine and arginine-modified lipoproteins from the plasma of rats and monkeys. |
| PubMed: | Receptor-mediated low density lipoprotein catabolism in man. |
| PubMed: | Amino acid sequence of the ribosomal protein L21 of Escherichia coli. |
| PubMed: | Identification of the C-1-phosphate-binding arginine residue of rabbit-muscle aldolase. Isolation of 1,2-cyclohexanedione-labeled peptide by chemisorption chromatography. |
| PubMed: | Decreased heparin sensitivity of cyclohexanedione-modified factor Xa. |
| PubMed: | Porcine pancreatic lipase. Sequence of the first 234 amino acids of the peptide chain. |
| PubMed: | A functional arginine residue in NADPH-dependent aldehyde reductase from pig kidney. |
| PubMed: | Modification of an arginine residue of a base-nonspecific ribonuclease from Aspergillus saitoi. |
| PubMed: | Complete amino acid sequence of the myoglobin from the Pacific spotted dolphin, Stenella attenuata graffmani. |
| PubMed: | The importance of arginyl residues for phosphorylation of rat liver cell sap proteins. |
| PubMed: | Circular dichroism of chemically modified human plasma alpha1-antitrypsin. Interaction with porcine elastase. |
| PubMed: | Collagen-induced platelet aggregation and release. I Effects of side-chain modifications and role of arginyl residues. |
| PubMed: | [Effect of chemical modification and carboxylate anions on transamination of phenylalanine and alanine in the active center of chicken cytosol aspartate transaminase]. |
| PubMed: | A catalytic role for heparin. Evidence for a ternary complex of heparin cofactor thrombin and heparin. |
| PubMed: | Complete amino acid sequence of myoglobin from the pilot whale, Globicephala melaena. |
| PubMed: | An essential arginine residue in human prostatic acid phosphatase. |
| PubMed: | Nonimmunospecific protein-protein interactions of IgG: studies of the binding of IgG to IgG immunoadsorbents. |
| PubMed: | Decreased heparin sensitivity of cycholhexanedione-modified thrombin. |
| PubMed: | [Study of the role of arginine residues in aspartate transaminase from chicken heart cytosol]. |
| PubMed: | Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. IV. The COOH-terminal 669 residues of the peptide chain; comparison with other glutamate dehydrogenases. |
| PubMed: | Essential arginyl residues in yeast phosphoglyceromutase. |
| PubMed: | Correlation between arginyl residue modification and benzodiazepine binding to human serum albumin. |
| PubMed: | The complete amino acid sequence of the major component myoglobin of dwarf sperm whale (Kogia simus). |
| PubMed: | Arginine modification in Kunitz bovine trypsin inhibitor through 1, 2-cyclohexanedione. |
| PubMed: | The reactive site of eggplant trypsin inhibitor. |
| PubMed: | Preparation and properties of carp muscle parvalbumin fragments A (residues 1 leads to 75) and B (residues 76 leads to 108). |
| PubMed: | Identification of a functional arginine residue involved in coenzyme binding by the NADP-specific glutamate dehydrogenase of Neurospora. |
| PubMed: | [The structure of photoreaction product of 1,2-cyclohexanedione. I (author's transl)]. |
| PubMed: | Role of arginine residues in ovine lutropin: reversible modification by 1,2-cyclohexanedione. |
| PubMed: | Determination of arginine in the reactive site of proteinase inhibitors by selective and reversible derivatization of the arginine side chain. |
| PubMed: | Functional arginine residues involved in coenzyme binding by glutamate dehydrogenases. |
| PubMed: | Studies on trypsin inhibitor in barley. I. Purification and some properties. |
| PubMed: | Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues. |
| PubMed: | Conformation and immunochemistry of parvalbumin 3 from pike white muscle. Modification of the arginine residue with 1,2-cyclohexanedione. |
| PubMed: | Synthesis of 3-hydroxy-3-(hydroxymethyl)-5-methyl-1,2-cyclohexanedione, a hydrolytic product of leucogenenol. |
| PubMed: | Obviation of destructive action of 0.2 M NaOH on proteins during arginine modification with cyclohexanedione by use of 0.1 M triethylamine as solvent. |
| PubMed: | The metabolism of cyclohexanol by Nocardia globerula CL1. |
| PubMed: | Modification of arginines in trypsin inhibitors by 1,2-cyclohexanedione. |
| PubMed: | Studies on the chemical modification of arginine. I. The reaction of 1,2-cyclohexanedione with arginine and arginyl residues of proteins. |
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