nutty quinoxaline
5,6,7,8-tetrahydroquinoxaline
 
Notes:
Flavour ingredient. Present in wheat bread, cocoa, coffee, roasted filbert, roasted peanut, pork and roasted sesame
  • Advanced Biotech
    • Advanced Biotech. Inc.
      Inspired by Nature
      A diverse range of products, all meeting our stringent commitment to quality.
      Advanced Biotech is a leading manufacturer and supplier of high-quality Natural flavoring ingredients & botanical extracts for the food/beverage, cosmetic and personal care industries. With over 25 years of experience working with Fermentation processing & botanical extracts, we can help develop new innovative and functional products for today‪s competitive marketplace. Our company prides itself in the ability to cater to our customer‪s specific needs while maintaining our focus on integrity, honesty and the commitment to high quality product standards. We proudly offer our quality Natural ingredients to companies around the world.
      US Email: Info
      US Email: Quotes and Orders
      US Voice: 973-339-6242
      US Fax: 973-256-4101
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      Product(s):
      4033 5,6,7,8 TETRAHYDROQUINOXALINE
      SDS
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
      Email: Mr. Guo
      Voice: 86-10-68418738
      Fax: 86-10-68418739
      Mr. Guo86-10-68483445
      Mr. Guo86-10-68418739
      News
      Product(s):
      10211 5,6,7,8-Tetrahydroquinoxaline
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
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      US Email: Sales
      Voice: 1-631-504-6093
      Fax: 1-631-614-7828
      US Voice: 1-631-504-6093
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      Europe44-203-286-1088
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      Product(s):
      34413-35-9 5.6.7.8-Tetrahydroquinoxaline
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
      Email: Sales
      Voice: 203-299-3220
      Fax: 203-299-1355
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      Product(s):
      TETRAHYDROQUINOXALINE,5,6,7,8- FEMA 3321
       
  • DeLong Chemicals America
    • DeLong Chemicals America
      Custom Manufacturing
      Supplier of aroma chemicals, pharmaceutical and specialty chemical intermediates.
      DeLong Chemicals America, LLC is an extension of Shijiazhuang Lida Chemical Co, Ltd to North America, a leading supplier and manufacturer of aroma chemicals, serving the industries of food, tobacco and perfume, while also providing intermediates, custom synthesis and custom manufacturing for pharmaceutical and specialty chemical industries.
      US Email: Customer Service
      US Email: Sales
      US Voice: (203) 271-9017
      New products
      Product(s):
      0618 5,6,7,8-Tetrahydroquinoxaline, Kosher
       
  • Endeavour Specialty Chemicals
    • Endeavour Specialty Chemicals Ltd
      Expertise in high impact aroma chemicals
      Endeavour Speciality Chemicals offers high-impact aroma chemicals, at small to medium scale.
      Speciality Chemical has more than 25 years experience of manufacturing high-impact aroma chemicals. With our core expertise in sulfur and heterocyclic chemistries, Endeavours products have applications in a range of industry sectors including flavours and fragrances, pharmaceutical research and material sciences. Endeavour also offer custom synthesis and contract manufacturing services at their UK manufacturing site.
      Email: Info
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      Voice: +44 (0)1327 310 079
      Fax: +44 (0)1327 310 701
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      Speciality Chemical Product Groups
      Product(s):
      QU0040 5,6,7,8-Tetrahydroquinoxaline
       
  • FCI SAS
    • FCI SAS
      Inspired by Nature
      At FCI customer service is not a department it’s an attitude.
      Our team is composed of motivated professionals with great experience in the flavours and fragrances market. Our company has been serving this industry for more than 40 years and is ISO 9001 certified since 2009 . Whatever your question on flavour and fragrance ingredients: commercial, technical or regulatory – we will answer it very quickly.
      Email: Info
      Email: Philippe Faucher
      US Email: USA Sales
      Email: Germany Sales
      Email: Italy Sales
      Email: Japan Sales
      Voice: +33 (0)1 34 25 58 10
      Fax: + 33 1 34 25 58 18
      About Us
      Product(s):
      50082 TETRAHYDROQUINOXALINE
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
      A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses.
      Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients.
      Email: Information
      US Voice: 845-341-2100
      US Fax: 845-341-2121
      Product(s):
      5,6,7,8-tetrahydroquinoxaline
       
  • Indukern F&F
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
      Email: Info
      Email: Sales
      Voice: 86-510-86023169
      Fax: 86-510-86023170
      Mobile0086-13093133011
      Services
      Biochemical
      Natural Food Colour
      New functional food ingredients
      Product(s):
      HL0135 5,6,7,8-Tetrahydroquinoxaline
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
      News
      Product(s):
      H0052 5,6,7,8-TETRAHYDROQUINOXALINE, Kosher
       
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
      Email: Contact Us:
      US Email: Dean Matienzo
      Email: Sales
      US Email: Dean Matienzo - Sales Manager
      Voice: +44 1993 843081
      Fax: +44 1993 841261
      US Voice: +1 973 886 3778
      US Fax: +1 973 346 1106
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      Website
      Global Distribution
      Product(s):
      5,6,7,8-Tetrahydro Quinoxaline
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
      US Email: Sales
      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      20-19500 5,6,7,8-TETRAHYDROQUINOXALINE
       
  • Robinson Brothers
  • Sigma-Aldrich
  • Sunaux International
    • Sunaux International
      Buy With Confidence
      We have industry leading processes and procedures to ensure nothing but the most reliable product.
      Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business.
      Email: John Felton
      Email: Stephen Zhou (Sales)
      Voice: 0512-57995626
      Fax: 0512-57570299
      Sales0512-57995626
      Sales0512-57570299
      News
      Product(s):
      H0052 5,6,7,8-Tetrahydroquinoxaline
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
      US Email: Customer Service
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      US Voice: (404) 524-6744
      US Fax: (404) 577-1651
      Inquiry
      Products List: View
      Product(s):
      Q823 5,6,7,8-Tetrahydroquinoxaline also named Cyclohexapyrazine
       
  • Taytonn
    • TAYTONN PTE LTD
      Supplying Asia Pacific
      We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
      Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
      Email: Info
      Email: Sales
      Voice: + 65 - 6861 8113
      Fax: + 65 - 6861 8115
      Product(s):
      5,6,7,8-Tetrahydroquinoxaline
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
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      Product(s):
      T1403 5,6,7,8-Tetrahydroquinoxaline >98.0%(GC)(T)
       
  • Tianjin Danjun International
    • Tianjin Danjun International Trade Co., LTD.
      Quality Products
      We know the Chinese chemical market well.
      Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
      Email: Info
      Email: Sales
      Voice: +86-15822601686
      Products List: View
      Product(s):
      B-031 5,6,7,8-Tetrahydroquinoxaline
       
  • R C Treatt & Co Ltd
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
      Email: Info
      Email: Sales
      Voice: +86-532-83893699
      Fax: +86-532-83893695
      Product(s):
      1017 5,6,7,8-Tetrahydroquinoxaline
       
  • Vigon International
    • Vigon International, Inc.
      Passion for Simplicity
      Manufacturer and supplier of high quality flavor and fragrance ingredients.
      The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities.
      US Email: Sales
      US Voice: 570-476-6300
      US Fax: 570-476-1110
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      Products List: View
      Product(s):
      505044 Tetrahydroquinoxaline-5,6,7,8
       
  • WholeChem
    • WholeChem, LLC
      Connecting Innovators To the Building Blocks Of the Universe
      Custom manufacturer and distributor of specialty ingredients. We make global local.
      We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing.
      Email: Info
      Email: Orders
      Voice: +1 (262) 995.8668
      Certification
      Products List: View
      Product(s):
      5.6.7.8-Tetrahydroquinoxaline
       
Synonyms   Articles   Notes   Search
CAS Number: 34413-35-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 252-002-8
FDA UNII: M153CJ9RA0
Nikkaji Web: J250.881H
MDL: MFCD00038078
CoE Number: 721
XlogP3-AA: 0.90 (est)
Molecular Weight: 134.18170000
Formula: C8 H10 N2
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 952  5,6,7,8-tetrahydroquinoxaline
DG SANTE Food Flavourings: 14.015  5,6,7,8-tetrahydroquinoxaline
FEMA Number: 3321 5,6,7,8-tetrahydroquinoxaline
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):34413-35-9 ; 5,6,7,8-TETRAHYDROQUINOXALINE
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to amber clear solid (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.07700 to 1.08700 @  25.00 °C.
Pounds per Gallon - (est).: 8.962 to  9.045
Refractive Index: 1.53800 to 1.54800 @  20.00 °C.
Melting Point: 29.00 to  30.00 °C. @ 760.00 mm Hg
Boiling Point: 108.00 to  111.00 °C. @ 760.00 mm Hg
Boiling Point: 85.00 °C. @ 3.00 mm Hg
Vapor Pressure: 0.055000 mmHg @ 25.00 °C. (est)
Vapor Density: 4.6 ( Air = 1 )
Flash Point: 195.00 °F. TCC ( 90.56 °C. )
logP (o/w): 1.158 (est)
Shelf Life: 12.00 month(s) or longer if stored properly.
Storage: refrigerate in tightly sealed containers.
Soluble in:
 alcohol
 water, slightly
 water, 2091 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: nutty
 
Odor Strength: high ,
recommend smelling in a 0.10 % solution or less
 
 musty  nutty  roasted  beany  cereal  corn chip  cheesy  
Odor Description:
at 0.10 % in dipropylene glycol. 
musty nut roasted bean cereal corn chip cheese
 
 musty  nutty  roasted  beany  cereal  
Odor Description:
Musty, nutty, roasted, beany, cereal cracker-like, with corn nuances
Mosciano, Gerard P&F 19, No. 2, 55, (1994)
 
 
Flavor Type: nutty
 
 nutty  musty  corn  taco  popcorn  
Taste Description:
at 10.00 ppm.  
Nutty, musty, corn taco and popcorn-like
Mosciano, Gerard P&F 19, No. 2, 55, (1994)
 
Odor and/or flavor descriptions from others (if found).
 
R C Treatt & Co Ltd
5,6,7,8-Tetrahydroquinoxaline Halal, Kosher
Odor Description: Fatty/cheesy
Taste Description: nutty, roasted, cereal
 
Frutarom
5,6,7,8-TETRAHYDROQUINOXALINE
Odor Description: Bean, Musty, Nutty, Roast
Suggested Uses: Bakery, Cheese, Chocolate, Cocoa, Nut, Vanilla
 
OQEMA
5,6,7,8-Tetrahydro Quinoxaline
Odor Description: Fatty/cheesy
Taste Description: nutty, roasted, cereal
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Advanced Biotech
5,6,7,8 TETRAHYDROQUINOXALINE
Ambles Nature et Chimie
5.6.7.8-TETRAHYDROQUINOXALINE
Anhui Haibei
5,6,7,8-Tetrahydroquinoxaline
Odor: Musty nut roasted bean cereal cracker corn cheese
Anhui Suzhou Jinli Aromatic Chemicals
5,6,7,8-Tetrahydro quinoxaline
Odor: baked hazel nut, baked peanut
Beijing Lys Chemicals
5,6,7,8-Tetrahydroquinoxaline
BOC Sciences
For experimental / research use only.
5.6.7.8-Tetrahydroquinoxaline
Charkit Chemical
TETRAHYDROQUINOXALINE,5,6,7,8- FEMA 3321
De Monchy Aromatics
5,6,7,8-Tetrahydroquinoxaline
DeLong Chemicals America
5,6,7,8-Tetrahydroquinoxaline, Kosher
Endeavour Specialty Chemicals
5,6,7,8-Tetrahydroquinoxaline
Speciality Chemical Product Groups
FCI SAS
TETRAHYDROQUINOXALINE
Odor: Roasted peanut
Fleurchem
5,6,7,8-tetrahydroquinoxaline
Indukern F&F
TETRAHYDROQUINOXALINE
Odor: CHEESE, NUTTY, CEREAL
Jiangyin Healthway
5,6,7,8-Tetrahydroquinoxaline
New functional food ingredients
Jinan Enlighten Chemical Technology(Wutong Aroma )
5,6,7,8-Tetrahydro quinoxaline, Kosherk
M&U International
5,6,7,8-TETRAHYDROQUINOXALINE, Kosher
OQEMA
5,6,7,8-Tetrahydro Quinoxaline
Penta International
5,6,7,8-TETRAHYDROQUINOXALINE
R C Treatt & Co Ltd
5,6,7,8-Tetrahydroquinoxaline
Halal, Kosher
Odor: Fatty/cheesy
Flavor: nutty, roasted, cereal
Robinson Brothers
5,6,7,8-Tetrahydroquinoxaline F&F
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
5,6,7,8-Tetrahydroquinoxaline
Sigma-Aldrich
5,6,7,8-Tetrahydroquinoxaline, ≥97%, FG
Odor: cheese
Certified Food Grade Products
Sunaux International
5,6,7,8-Tetrahydroquinoxaline
Synerzine
5,6,7,8-Tetrahydroquinoxaline
also named Cyclohexapyrazine
Taytonn
5,6,7,8-Tetrahydroquinoxaline
Odor: Bean, Musty, Nutty, Roast
TCI AMERICA
For experimental / research use only.
5,6,7,8-Tetrahydroquinoxaline >98.0%(GC)(T)
Tengzhou Jitian Aroma Chemiclal
5,6,7,8-Tetrahydroquinoxaline
Tengzhou Xiang Yuan Aroma Chemicals
5.6.7.8-Tetrohydro quinoxaline
Tianjin Danjun International
5,6,7,8-Tetrahydroquinoxaline
United International
5,6,7,8-Tetrahydroquinoxaline
Vigon International
Tetrahydroquinoxaline-5,6,7,8
WholeChem
5.6.7.8-Tetrahydroquinoxaline
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for nutty quinoxaline usage levels up to:
  0.1000 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 8.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): ND (μg/capita/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5
Click here to view publication 5
 average usual ppmaverage maximum ppm
baked goods: -5.00000
beverages(nonalcoholic): -5.00000
beverages(alcoholic): --
breakfast cereal: -2.00000
cheese: --
chewing gum: --
condiments / relishes: -2.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: -2.00000
granulated sugar: --
gravies: -2.00000
hard candy: -5.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -2.00000
milk products: -1.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -2.00000
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1]
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Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24
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Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010)
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Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species
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EPI System: View
EPA Substance Registry Services (TSCA): 34413-35-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 36822
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 5,6,7,8-tetrahydroquinoxaline
Chemidplus: 0034413359
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References:
 5,6,7,8-tetrahydroquinoxaline
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 34413-35-9
Pubchem (cid): 36822
Pubchem (sid): 134999131
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB33154
FooDB: FDB011159
Export Tariff Code: 2933.99.8090
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
FAO: 5,6,7,8-Tetrahydroquinoxaline
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 sulfuryl octanoateFL/FR
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
 sulfuryl propionateFL/FR
anisic
para-anisaldehydeFL/FR
balsamic
2-acetyl furanFL/FR
isobutyl cinnamateFL/FR
 ethyl cinnamateFL/FR
 methyl cinnamateFL/FR
3-phenyl propyl alcoholFL/FR
bready
 coffee furanoneFL/FR
 cycloteneFL/FR
 immortelle absoluteFL/FR
 maltolFL/FR
isopropenyl pyrazineFL/FR
 strawberry furanoneFL/FR
cereal
 bran absoluteFR
chocolate
isoamyl phenyl acetateFL/FR
2,5-dimethyl pyrazineFL/FR
coconut
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
gamma-octalactoneFL/FR
coffee
 cichorium intybus root solid extractFL/FR
 popcorn pyrimidineFL/FR
earthy
 nutty pyrazineFL/FR
floral
 bois de rose oil brazilFL/FR
 ethyl phenyl acetateFL/FR
green
2-heptyl furanFL/FR
hay
 beeswax absoluteFL/FR
honey
 phenyl acetic acidFL/FR
medicinal
 quinolineCS
musty
2-acetyl pyrroleFL/FR
3-acetyl-2,5-dimethyl furanFL/FR
 hazelnut pyrazineFL/FR
 menthofuranFL/FR
2-acetyl-3-ethyl pyrazineFL/FR
2-acetyl-3-methyl pyrazineFL/FR
2-acetyl-3,5-dimethyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
5-acetyl-4-methyl thiazole 
2-acetyl-5-methyl furanFL/FR
roasted chestnut fragranceFR
3,6-cocoa pyrazineFL/FR
4,5-dimethyl-2-ethyl-3-thiazolineFL/FR
2,4-dimethyl-5-ethyl thiazole 
2-ethyl pyrazineFL/FR
 filbert heptenoneFL/FR
 filbert heptenone BFL/FR
 filbert pyrazineFL/FR
2,6-lutidineFL/FR
 methoxymethyl pyrazineFL/FR
5-methyl quinoxalineFL/FR
 nutty cyclohexenoneFL/FR
 sesame absoluteFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,3,5-trimethyl pyrazineFL/FR
 vinyl sulfurolFL/FR
popcorn
2-acetyl pyrazineFL/FR
2-acetyl thiazoleFL/FR
powdery
para-anisyl alcoholFL/FR
roasted
2-acetyl-2-pyrroline 
spicy
 cassia bark oil chinaFL/FR
 clove bud oilFL/FR
alpha-methyl cinnamaldehydeFL/FR
sulfurous
 dimethyl sulfideFL/FR
 furfuryl thioacetateFL/FR
tonka
 tonka bean absoluteFR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
woody
4-hydroxybenzaldehydeFL/FR
 
For Flavor
 
No flavor group found for these
 acetyl acetaldehyde dimethyl acetalFL
2-acetyl-2-pyrroline 
5-acetyl-4-methyl thiazole 
(E)-aconitic acidFL
 cyclohexyl methyl pyrazineFL
2,5-diethyl thiazoleFL
6,7-dihydro-2,3-dimethyl-5H-cyclopentapyrazineFL
 dimethyl dihydrocyclopentapyrazineFL
6,7-dimethyl dihydrocyclopentapyrazineFL
2,5-dimethyl pyrazine and 2,6-dimethyl pyrazine mixtureFL
2,5-dimethyl thiazoleFL
2,4-dimethyl-5-ethyl thiazole 
 methyl 2-(methyl thio) acetateFL
 pyrazines mixtureFL
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
5-acetyl-2,3-dihydro-1,4-thiazineFL
 sulfuryl formateFL
 sulfuryl octanoateFL/FR
 sulfuryl propionateFL/FR
ammoniacal
2-methyl piperidineFL
balsamic
isobutyl cinnamateFL/FR
 ethyl cinnamateFL/FR
bready
2-propionyl thiazoleFL
brown
 beeswax absoluteFL/FR
burnt
isopropenyl pyrazineFL/FR
buttery
 diacetylFL
caramellic
 caramel furanoneFL
 cycloteneFL/FR
 maltolFL/FR
 strawberry furanoneFL/FR
coconut
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
coffee
 cichorium intybus root solid extractFL/FR
corn chip
2-acetyl thiazoleFL/FR
2-acetyl-2-thiazolineFL
 popcorn pyrimidineFL/FR
creamy
para-anisaldehydeFL/FR
4-hydroxybenzaldehydeFL/FR
fatty
2-heptyl furanFL/FR
fishy
4,5-dimethyl thiazoleFL
floral
isoamyl phenyl acetateFL/FR
 bois de rose oil brazilFL/FR
 phenyl acetic acidFL/FR
fruity
para-anisyl alcoholFL/FR
2-ethyl-2,5-dihydro-4-methyl thiazoleFL
green
 immortelle absoluteFL/FR
honey
 ethyl phenyl acetateFL/FR
lactonic
gamma-octalactoneFL/FR
malty
 yeast thiazolineFL
musty
2,5-dimethyl pyrazineFL/FR
2-ethoxythiazoleFL
 hazelnut pyrazineFL/FR
 menthofuranFL/FR
2,3,5-trimethyl pyrazineFL/FR
nutty
2-acetyl furanFL/FR
2-acetyl pyrroleFL/FR
3-acetyl-2,5-dimethyl furanFL/FR
3-acetyl-2,5-dimethyl thiopheneFL
2-acetyl-3-ethyl pyrazineFL/FR
2-acetyl-3-methyl pyrazineFL/FR
2-acetyl-3,5-dimethyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
2-acetyl-5-methyl furanFL/FR
 arachis hypogaea fruit extractFL
3,6-cocoa pyrazineFL/FR
 coffee furanoneFL/FR
4,5-dimethyl-2-ethyl-3-thiazolineFL/FR
2-ethyl pyrazineFL/FR
1-ethyl-2-acetyl pyrroleFL
 filbert heptenoneFL/FR
 filbert heptenone BFL/FR
 filbert pyrazineFL/FR
2,6-lutidineFL/FR
 methoxymethyl pyrazineFL/FR
5-methyl quinoxalineFL/FR
 nutty cyclohexenoneFL/FR
 nutty pyrazineFL/FR
 nutty thiazoleFL
 peanut oxazoleFL
 sesame absoluteFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
 vinyl sulfurolFL/FR
popcorn
2-propionyl-2-thiazolineFL
roasted
2-acetyl pyrazineFL/FR
3,5-diisobutyl-1,2,4-trithiolaneFL
 furfuryl thioacetateFL/FR
spicy
 cassia bark oil chinaFL/FR
 clove bud oilFL/FR
alpha-methyl cinnamaldehydeFL/FR
 methyl cinnamateFL/FR
3-phenyl propyl alcoholFL/FR
sulfurous
 dimethyl sulfideFL/FR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
 
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Potential Uses:
 breadFL
 caramelFL
 cheeseFL
 chocolate cocoaFL
 cornFL
 corn chipFL
 filbertFR
 meatFL
 peanutFR
 pecanFL
 popcornFR
 potatoFL
 sesameFL
 vanillaFR
 walnutFL
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Occurrence (nature, food, other): note
 bread wheat bread
Search  PMC Picture
 cocoa
Search Trop  Picture
 coffee
Search  PMC Picture
 filbert roasted filbert
Search Trop  Picture
 hazelnut
Search Trop  Picture
 peanut
Search Trop  Picture
 peanut roasted peanut
Search Trop  Picture
 sesame roasted sesame seed
Search Trop  Picture
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Synonyms:
 cyclohexapyrazine
 quinoxaline, 5,6,7,8-tetrahydro-
5,6,7,8-tetrahydro quinoxaline
 tetrahydro terrazine-014 (IFF)
 tetrahydroquinoxaline
5,6,7,8-tetrahydroquinoxaline
5,6,7,8-tetrahydroquinoxaline natural
5,6,7,8-tetrahydroquinoxaline natural 1% in ethyl alcohol
5,6,7,8-tetrahydroquinoxaline natural 5% in ethyl alcohol
 tetrahydroterrazine (IFF)
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