Articles:
2,3,5,6-tetramethylpyrazine
Notes:
found in ligusticum chuanxiong. Isol. from Galbanum oil. Present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products. Fragrance and flavouring ingredient
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Advanced Biotech. Inc. Inspired by Nature A diverse range of products, all meeting our stringent commitment to quality. Advanced Biotech is a leading manufacturer and supplier of high-quality Natural flavoring ingredients & botanical extracts for the food/beverage, cosmetic and personal care industries. With over 25 years of experience working with Fermentation processing & botanical extracts, we can help develop new innovative and functional products for today’s competitive marketplace. Our company prides itself in the ability to cater to our customer’s specific needs while maintaining our focus on integrity, honesty and the commitment to high quality product standards. We proudly offer our quality Natural ingredients to companies around the world. US Email: Info US Email: Quotes and Orders US Voice: 973-339-6242 US Fax: 973-256-4101 Facebook Twitter Instagram Linkedin Pinterest Upcoming Events Blog Vimeo Product(s): 1463 2,3,5,6 TETRA METHYL PYRAZINE NATURAL 98% min. SDS 4010 2,3,5,6 TETRAMETHYL PYRAZINE SDS
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Alfrebro LLC/ Archer Daniels Midland Company Let's get reacquainted Building great taste with aroma chemicals, extracts, and distillates The Alfrebro brand was established in the early 1900s by Alex Fries & Brothers, a Cincinnati Flavor Company. In 1980, the brand was re-launched as an aroma chemical manufacturer. Since its inception, Alfrebro’s primary focus has been to provide quality natural and high value synthetic chemicals. Email: Sarah Forbis Email: Sales Voice: 513-539-3021 Fax: 513-539-7372 US Voice: 513-539-7373 Newsroom Product(s): 2,3,5,6-TETRAMETHYL PYRAZINE NATURAL 99%
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Augustus Oils Ltd The Premier Supplier Augustus Oils Ltd, in harmony with nature - to present it at its best... A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements. Email: Enquiries Email: Sales Email: web site enquiries Voice: +44 (0)1420 590555 Fax: +44 (0)1420 592420 Services Product(s): 2,3,5,6 Tetramethyl Pyrazine
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Axxence Aromatic GmbH We bring nature to your flavour Dedicated to provide the best possible quality and supply service of natural aroma ingredients. Axxence Aromatic is entirely dedicated to provide the best possible quality and supply service of natural aroma ingredients to the Flavour & Fragrance Industry worldwide. Email: Service Voice: +49.2822.68561.0 Fax: +49.2822.68561.39 Sustainability Products List: View Product(s): 323700 2,3,5,6-TETRAMETHYL PYRAZINE Natural
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Beijing Lys Chemicals Co, LTD. From Grams to Tons Fine chemical high-tech company which contains R&D, production, and sales. BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services. Email: Mr. Jia Email: Mr. Guo Voice: 86-10-68418738 Fax: 86-10-68418739 Mr. Guo 86-10-68483445 Mr. Guo 86-10-68418739 News Product(s): 10032 2,3,5,6-Tetramethyl pyrazine
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): B0005-464515 2,3,5,6-Tetramethylpyrazine >98%
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Charkit Chemical Corporation The Specialty Chemical Specialists Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you. about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals. Email: Sales Voice: 203-299-3220 Fax: 203-299-1355 Facebook Twitter Linkedin Latest News Events Blog Products List: View Product(s): TETRAMETHYLPYRAZINE, 2,3,5,6- FEMA 3237 TETRAMETHYLPYRAZINE, 2,3,5,6- NATURAL FEMA 3237
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CJ Latta & Associates, LLC Extensive Line Aromatic Chemicals and Organic Acids. CJ Latta & Associates is a distributor of specialty aromatics and organic acids used in the formulation of flavors and fragrance manufactured worldwide. We pride ourselves on our reputation for, fair pricing, quality and reliability. We’ve built our business on successfully sourcing and developing many challenging specialty chemicals and fine ingredients for our clients. Email: Info US Email: Chip Latta Email: Sales US Email: Chip Latta Voice: (630) 240-8079 Product(s): 2,3,5,6-TMP
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Excellentia International Ingredients by Nature Exceptional quality and excellence in meeting our customers requirements. Excellentia International was founded in 2010 through the merger of Excellentia Flavors LLC and Polarome International. Collectively, these companies account for more than one hundred years of industry experience, and are recognized for exceptional quality and excellence in meeting our customers’ requirements. Email: Info Email: Sales Email: Regulatory Voice: 732.749.9840 Our Services Product(s): 2,3,5,6-TetraMethyl Pyrazine Natural
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FCI SAS Inspired by Nature At FCI customer service is not a department it’s an attitude. Our team is composed of motivated professionals with great experience in the flavours and fragrances market. Our company has been serving this industry for more than 40 years and is ISO 9001 certified since 2009 . Whatever your question on flavour and fragrance ingredients: commercial, technical or regulatory – we will answer it very quickly. Email: Info Email: Philippe Faucher US Email: USA Sales Email: Germany Sales Email: Italy Sales Email: Japan Sales Voice: +33 (0)1 34 25 58 10 Fax: + 33 1 34 25 58 18 About Us Product(s): 50032 2,3,5,6-TETRAMETHYL PYRAZINE
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Fleurchem, Inc. Have A Flavorful Day A leading global manufacturer and supplier of ingredients for Flavors, Fragrances, AromaTherapy, Foods, Beverages, Personal Care Products, and other uses. Operating out of the 200,000 sq. ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors. Additionally, the company performs toll manufacturing, as well as custom chemical synthesis for a wide range of clients. Email: Information US Voice: 845-341-2100 US Fax: 845-341-2121 Product(s): tetramethyl pyrazine natural 2,3,5,6-tetramethyl pyrazine
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FRUTAROM USA INC, Flavor & Specialty Ingredients Your preferred partner for flavour and fragrance success. Our broad and diverse product portfolio is designed to provide and cater for every flavor and taste profile required by our customer base and incorporates historic, and iconic, market leading products. Email: Info US Email: Info- USA Email: Sales Voice: +44 (0) 1429 863 222 CBD Offering Products List: View Product(s): 441T030000 2-3-5-6-TETRAMETHYLPYRAZINE KOSHER
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Indukern, S.A. F&F Ingredients Division Commitment to quality Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients. Indukern F&F focuses in particular on the service it offers its clients in terms of quality, speed and direct consultancy with more than 1600 different products in stock ready for prompt shipment: Aromachemicals, Essential Oils and Natural Isolates. Email: Info Email: Luciana Soares (Brazil) Email: Gabriela Garcia (Mexico) Email: Jorge Eduardo Clavijo (Colombia) Voice: +34 93 506 91 00 Fax: +34 93 506 91 95 Services Quality Facilities Products List: View Product(s): 2,3,5,6-TETRAMETHYL PYRAZINE 2,3,5,6-TETRAMETHYL PYRAZINE NATURAL
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Jiangyin Healthway International Trade Co., Ltd Independent Ingredients Supplier We provide custom synthesis and contract manufacturing from milligrams to metric tonnes. Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals. Email: Info Email: Sales Voice: 86-510-86023169 Fax: 86-510-86023170 Mobile 0086-13093133011 Services Biochemical Natural Food Colour New functional food ingredients Product(s): HL0106 2,3,5,6-Tetramethyl Pyrazine HLW-FC119 Tetramethylpyrazine
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Lluch Essence S.L. A family company dedicated to sales and distribution Flexibility, availability, price and quality. Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world. Email: Info Voice: 34 93 379 38 49 Fax: 34 93 370 65 04 Linkedin Product(s): PYRAZINE 2,3,5,6-TETRAMETHYL PYRAZINE 2,3,5,6-TETRAMETHYL NATURAL
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M&U International LLC Steady supply & demand Meeting customers increasing demands at home as well as abroad. M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. Email: Sales US Email: Sales Voice: +86-21-32515501 60762991 60762992 Fax: +86-21-32515502 64204960 US Voice: 908-359-9000 US Fax: 908-359-9002 News Product(s): H0018 2,3,5,6-TETRAMETHYLPYRAZINE, Kosher N0137 NAT.2,3,5,6-TETRAMETHYLPYRAZINE, Kosher
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Moellhausen S.P.A. THE CHEMISTRY OF EMOTIONS Innovation and commitment in the name of excellence. After 50 years in business, Moellhausen stands out as one of the world’s leading family-run companies in the industry of flavors and fragrances, raw materials, and specialties. Voice: +39 039.685.6262 Fax: +39 039.685.6263 Facebook Twitter Linkedin Youtube A network of knowledge to grow together Sustainability is at the foundation of a Pervasive technology and total control Product(s): 100849 2,3,5,6-TETRAMETHYL PYRAZINE
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Myrazine LLC EU Natural Ingredients from Fermentation All the materials are sourced from fermentation. Myrazine LLC,formerly known as Cheng Smith LLC, and Abioco, started its search for Natural materials in 2000, when we started to import natural alcohols from China. China's liquor fermentation technology is as old as the country. Chinese liquor is? unique, because it is fermented from grains, such as rice, wheat, sorghum, and barleys. With bacteria or microorganism present in the fermentaiton, Chinese liquor is rich in flavours. It is reported that there are over 100 flavour materials in the liquor fermentation broth. During the production, the "good" liquor is distilled out, and the "bad" alcohols are dumped as "wastes" before 1980s. Fusel oil is regarded and dumped as the "bad" one during the production. Today, every single ton of the liquor fermentation "wastes" --- fusel oil, has been physically distilled. Alcohols from these distillations are methyl alcohol, ethanol, propanol, butanol, iso-butanol, iso-amyl alcohol, etc. Most of the alcohols are used by the flavour and fragrances industry as raw materials, which eventually go into the beverages, food, and some daily products. According to the US and EU regulations about natural ingredients, materials from fermentation are regarded as "natural". Email: Info Email: Sales Voice: +1.623 565 7047 Product(s): Tetramethyl Pyrazine Tetramethylpyrazine/EU Nat.
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Natural Advantage Manufacturer of natural flavor ingredients With over 25 years experience in the flavor and food ingredient industries. Technology Improving Taste Natural Advantage was formed over seventeen years ago to supply the growing demand for natural food and flavor ingredients. We employ a wide range of multi-disciplined scientists who are dedicated to high quality service, customer satisfaction and creating an outstanding value for our clients. Email: Info Email: Customer service Voice: 318-215-1456 Fax: 318-335-1579 Facebook Twitter Instagram Linkedin Who We Are Technology Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries Products List: View Product(s): NA3237 Tetramethyl pyrazine Nat
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Pell Wall Perfumes Hand-made fragrances Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock. Pell Wall was founded by perfumer Chris Bartlett to provide exclusive hand-made fragrances to a select few people who love them. All our products are created using fine quality ingredients, many of which we also offer for sale to other perfumers and enthusiasts. Pell Wall make fragrances for men, for women and for the home. Email: Info Email: Sales Voice: +44 (0) 20 3745 0887 Facebook Twitter Instagram Blog Product(s): Tetramethyl Pyrazine As with all pyrazines this is used in traces – Tetramethyl Pyrazine at 0.1% in Ethanol has a distinctively chocolate odour with elements of roasted nuts and a distinctive tea element. Very useful as part of an authentic chocolate and black tea accords, but must be used with a very light touch.
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 20-21200 2,3,5,6-TETRAMETHYL PYRAZINE NATURAL 20-21500 2,3,5,6-TETRAMETHYLPYRAZINE SYNTHETIC
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Anhui Primechem Co., Ltd. Where Scent Matters Most Dependable supply and professional services to exceed our client's expectations. For over 2 decades, Primechem has proven to be a professional and outstanding supplier, offering a diverse range of superior quality products, services and solutions for use in Flavor & Fragrances industries worldwide. Email: Info Email: Sales Voice: +86-551-628 355 29 Fax: :+86-551-628 330 59 News and Events At a glance Products List: View Product(s): 2,3,5,6-Tetramethylpyrazine natural
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Riverside Aromatics Ltd. Speciality Aroma Chemicals, Naturals and Synthetics A specialist supplier of raw materials to the flavour industry. Peter Cannon & David Rowe established Riverside Aromatics in 2006 in Poole, UK, to offer a new type of specialist raw material supplier to the Flavour & Fragrance Industry. We bring together over 40 years of commercial & technical experience in the F&F industry which allows us to understand the needs of the Global F&F business and especially that of the West European Market. Email: Info Email: Peter Cannon (sales) Voice: +44 (0) 1202 679532 Fax: +44 (0) 1202 679532 Products List: View Product(s): TP0200 2,3,5,6-TETRAMETHYLPYRAZINE
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Sigma-Aldrich Complete Supply Chain The perfect blend of products and services that bring your creativity to life. Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards. Email: Information US Email: Sales US Voice: 800-244-1173 US Fax: 800-368-4661 Facebook Twitter Instagram Linkedin Flavors and Fragrances Analysis FandF Newsletter Subscription Flavors and Fragrances Learning Center Certified Food Grade Products Product(s): W323705 2,3,5,6-Tetramethylpyrazine, ≥98%, FG SDS W323713 2,3,5,6-Tetramethylpyrazine, natural, ≥98%, FG SDS
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Sunaux International Buy With Confidence We have industry leading processes and procedures to ensure nothing but the most reliable product. Sunaux International was founded in 2012 by the owner Mr.John Felton after spending 18 years involved in developing global business in the aromatic chemicals, fragrance and flavour compounds business. Email: John Felton Email: Stephen Zhou (Sales) Voice: 0512-57995626 Fax: 0512-57570299 Sales 0512-57995626 Sales 0512-57570299 News Product(s): H0018 2,3,5,6-Tetramethylpyrazine N0152 nat.2,3,5,6-Tetramethylpyrazine
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Synerzine, Inc. Innovation. Customization. Aroma Ingredients. Synerzine is a leading supplier of flavor and fragrance ingredients. Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust. Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster. US Email: Customer Service US Email: Sales US Voice: (404) 524-6744 US Fax: (404) 577-1651 Inquiry Products List: View Product(s): N302 2,3,5,6-Tetramethylpyrazines Natural 846 2,3,5,6-Tetramethylpyrazine
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Taytonn ASCC Pte Ltd Supplying Asia Pacific We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service. Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers. Email: Info Email: Sales Voice: + 65 - 6861 8113 Fax: + 65 - 6861 8115 Linkedin Product(s): 2,3,5,6-Tetramethylpyrazine Natural Tetramethylpyrazine
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TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): T0972 2,3,5,6-Tetramethylpyrazine >98.0%(GC)(T) SDS
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Tianjin Danjun International Trade Co., LTD. Quality Products We know the Chinese chemical market well. Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service. Email: Info Email: Sales Voice: +86-15822601686 Products List: View Product(s): B-010 2,3,5,6-Tetramethyl pyrazine
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R C Treatt and Co Ltd Innovative ingredient solutions World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries. We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products. Email: Enquiries US Email: Enquiries Voice: +44 (0) 1284 702500 Fax: +44 (0) 1284 703809 US Voice: +1 863 668 9500 US Fax: +1 863 668 3388 Twitter Linkedin Youtube News Product(s): 2,3,5,6-Tetramethylpyrazine NI, Kosher
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Qingdao Free Trade Zone United International Co Ltd Quality Products A partner in your supply chain solution. Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information. Email: Info Email: Sales Voice: +86-532-83893699 Fax: +86-532-83893695 Product(s): 1007 2,3,5,6-Tetramethyl Pyrazine 1007N 2,3,5,6-Tetramethyl Pyrazine Nat.
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Ernesto Ventós S.A. Leaders in essence We employ our five senses to do our job well. Ventos has specialized in the distribution of raw materials for the flavour and fragrance industry. With more than 1700 references permanently available from stock, we offer a just-in-time response to our customer needs, being able to deliver from 1kg to several tonnes all over the world. Email: Information US Email: Information USA Email: Gemma Parramon (Europe) US Email: Gemma Parramon (Europe) Email: Jorge Sos (Asia) Email: Ramon Rubau (America) Voice: +34 934706210 Fax: +34 934733010 US Voice: +1 856 226 7501 Instagram Linkedin Youtube Press Ads Videos Product(s): 2,3,5,6-TETRAMETHYLPYRAZINE 2,3,5,6-TETRAMETHYLPYRAZINE NATURAL
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Vigon International Passion for Simplicity Manufacturer and supplier of high quality flavor and fragrance ingredients. The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities. US Email: Sales US Voice: 570-476-6300 US Fax: 570-476-1110 Facebook Twitter Linkedin Newsletter Blog Products List: View Product(s): 505051 Tetramethyl-2,3,5,6 Pyrazine Natural
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WholeChem, LLC Connecting Innovators To the Building Blocks Of the Universe Custom manufacturer and distributor of specialty ingredients. We make global local. SQF-Certified Supplier We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing. Email: Info Email: Orders Voice: +1 (262) 995.8668 Certification Our Services Products List: View Product(s): 2.3.5.6-Tetramethyl pyrazine 2,3,5,6-Tetramethylpyrazine, Natural
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| Flavor Demo Formulas | ||
| CAS Number: | 1124-11-4 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 214-391-2 | |
| FDA UNII: | V80F4IA5XG | |
| Nikkaji Web: | J39.647H | |
| Beilstein Number: | 0113100 | |
| MDL: | MFCD00006146 | |
| CoE Number: | 734 | |
| XlogP3: | 1.30 (est) | |
| Molecular Weight: | 136.19764000 | |
| Formula: | C8 H12 N2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) | |
Category: cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 780 2,3,5,6-tetramethylpyrazine |
| DG SANTE Food Flavourings: | 14.018 2,3,5,6-tetramethylpyrazine |
| FEMA Number: | 3237 2,3,5,6-tetramethylpyrazine |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 1124-11-4 ; 2,3,5,6-TETRAMETHYLPYRAZINE |
Physical Properties:
| Appearance: | white crystals (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | Yes |
| Melting Point: | 85.00 to 90.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 190.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.671000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 4.7 ( Air = 1 ) |
| Flash Point: | > 200.00 °F. TCC ( > 93.33 °C. ) |
| logP (o/w): | 1.280 |
| Soluble in: | |
| alcohol | |
| fixed oils | |
| propylene glycol | |
| water, 7007 mg/L @ 25 °C (est) | |
| Stability: | |
| alcoholic fine fragrance, good | |
| antiperspirant, good | |
| fabric softener, good | |
| hypochlorite bleach, poor | |
| liquid detergent, good | |
| perborate powder detergent, good | |
| soap, good | |
| toiletry application, good | |
Organoleptic Properties:
| Odor Type: nutty | |
| nutty musty chocolate coffee cocoa brown lard burnt | |
| Odor Description: at 10.00 % in dipropylene glycol. | nutty musty chocolate coffee cocoa brown lard burnt Luebke, William tgsc, (2017) |
| nutty musty vanilla dry brown cocoa | |
| Odor Description: | Nutty, musty and vanilla with dry, brown cocoa nuances Mosciano, Gerard P&F 22, No. 2, 69, (1997) |
| Flavor Type: nutty | |
| nutty musty weedy earthy cocoa peanut coffee asparagus | |
| Taste Description: | nutty musty weedy earthy cocoa peanut coffee asparagus Luebke, William tgsc, (2017) |
| nutty musty cocoa dry peanut raw coffee | |
| Taste Description: at 150.00 ppm. | Nutty, musty, cocoa, drying, peanut-like and raw coffee notes Mosciano, Gerard P&F 22, No. 2, 69, (1997) |
| Odor and/or flavor descriptions from others (if found). | |
| Moellhausen | |
| 2,3,5,6-TETRAMETHYL PYRAZINE | |
| Odor Description: | smoke, herbaceous, dry |
| Taste Description: | sweet, chocolate, coffee, cocoa, fermented |
| Alfrebro | |
| 2,3,5,6-TETRAMETHYL PYRAZINE NATURAL 99% | |
| Odor Description: | Nutty Chocolate Coffee |
| Pell Wall Perfumes | |
| Tetramethyl Pyrazine | |
| Odor Description: | Nutty, chocolate, roasted, tea. Powerful As with all pyrazines this is used in traces – Tetramethyl Pyrazine at 0.1% in Ethanol has a distinctively chocolate odour with elements of roasted nuts and a distinctive tea element. Very useful as part of an authentic chocolate and black tea accords, but must be used with a very light touch. |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
perfuming agents |
Suppliers:
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xn - Harmful. | |
|
R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. R 41 - Risk of serious damage to eyes. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
gavage-rat LD50 1910 mg/kg (Oser, 1969g) intravenous-mouse LD50 239 mg/kg Chinese Medical Journal Vol. 4, Pg. 319, 1978. intraperitoneal-mouse LD50 800 ug/kg International Journal of Crude Drug Research. Vol. 23, Pg. 119, 1985. oral-rat LD50 1910 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic, flavor and fragrance agents | ||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for 2,3,5,6-tetramethyl pyrazine usage levels up to: | |||
| 0.6000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 6.70 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 19.00 (μg/capita/day) | ||
| Structure Class: | II | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 4 | |||
| Click here to view publication 4 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 5.00000 | |
| beverages(nonalcoholic): | - | 5.00000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | 10.00000 | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | 10.00000 | |
| hard candy: | - | 5.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | 10.00000 | |
| milk products: | - | 5.00000 | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | 10.00000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf | |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf | |
| Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf | |
| Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 1124-11-4 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 14296 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 2,3,5,6-tetramethylpyrazine | |
| Chemidplus: | 0001124114 |
| RTECS: | UQ3905000 for cas# 1124-11-4 |
References:
| 2,3,5,6-tetramethylpyrazine | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 1124-11-4 |
| Pubchem (cid): | 14296 |
| Pubchem (sid): | 134980455 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | HMDB36584 |
| FooDB: | FDB015495 |
| Export Tariff Code: | 2933.99.9700 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| chocolate cocoa | FL | |
| coffee | FL | |
| filbert | FL | |
| galbanum | FR | |
| green | FL | |
| guava | FL | |
| lard | FL | |
| macadamia | FL | |
| peanut | FL | |
| soybean | ||
| sugar brown sugar | FL |
Occurrence (nature, food, other): note
| beef roasted beef Search PMC Picture | |
| cheese cheddar cheese Search PMC Picture | |
| cocoa products Search Trop Picture | |
| coconut endosperm Search Trop Picture | |
| coffee Search PMC Picture | |
| dairy products Search PMC Picture | |
| egg boiled egg Search PMC Picture | |
| filbert Search Trop Picture | |
| galbanum Search Trop Picture | |
| guava fruit Search Trop Picture | |
| macadamia nut Search Trop Picture | |
| meat Search PMC Picture | |
| peanut Search Trop Picture | |
| pepper bell pepper fruit Search Trop Picture | |
| rum Search PMC Picture | |
| shrimp Search PMC Picture | |
| soy products Search PMC Picture | |
| soybean seed Search Trop Picture | |
| tea green tea Search Trop Picture | |
| tea leaf Search Trop Picture | |
| whiskey Search Picture |
Synonyms:
| chuanxingzine | |
| ligustrazine | |
| pyrazine, 2,3,5,6- tetramethyl | |
| pyrazine, 2,3,5,6-tetramethyl- | |
| 2,3,5,6- | tetra methyl pyrazine |
| 2,3,5,6- | tetramethyl pyrazine |
| 2,3,5,6- | tetramethyl pyrazine (natural) |
| 2,3,5,6- | tetramethyl pyrazine FCC |
| tetramethyl pyrazine natural | |
| 2,3,5,6- | tetramethyl pyrazine natural |
| 2,3,5,6- | tetramethyl pyrazine, natural |
| tetramethylpyrazine | |
| 2, 3, 5, 6 | tetramethylpyrazine |
| 2,3,5,6- | tetramethylpyrazine |
| nat.2,3,5,6- | tetramethylpyrazine |
| 2,3,5,6- | tetramethylpyrazine natural |
| 2,3,5,6- | tetramethylpyrazine, synthetic |
| 2,3,5,6- | tetramethylpyrazines natural |
| tetrapyrazine |