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Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | Colorless to yellow clear liquid (est) |
| Assay: | 97.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.09100 to 1.09700 @ 25.00 °C.
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| Pounds per Gallon - (est).: | 9.078 to 9.128
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| Refractive Index: | 1.47500 to 1.48100 @ 20.00 °C.
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| Boiling Point: | 221.00 to 222.00 °C. @ 760.00 mm Hg
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| Acid Value: | 3.00 max. KOH/g
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| Vapor Pressure: | 0.103000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 162.00 °F. TCC ( 72.22 °C. )
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| logP (o/w): | 0.269 (est) |
| Soluble in: |
| | alcohol | | | water, 2.441e+004 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
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| Odor Type: moldy |
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| Odor Strength: | high , recommend smelling in a 1.00 % solution or less |
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| Substantivity: | > 384 hour(s) at 100.00 % |
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| | sweet moldy mushroom vegetable potato sugar burnt sugar nut skin wasabi caramellic fruity brandy |
Odor Description: at 1.00 % in dipropylene glycol. | sweet moldy mushroom vegetable potato burnt sugar nut skin wasabi caramellic fruity brandy Luebke, William tgsc, (2017) |
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| | musty sweet caramellic musty beany cocoa coffee meaty vegetable |
Odor Description: at 1.00 % in propylene glycol. | Musty, sweet, caramellic, musty beany, cocoa, coffee with slightly meaty and vegetative nuances Mosciano, Gerard P&F 24, No. 5, 41, (1999) |
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| Flavor Type: moldy |
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| | moldy earthy vegetable potato savory brown meaty |
Taste Description:
| moldy earthy vegetable potato savory brown meaty Luebke, William tgsc, (2017) |
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| | musty vegetable savory meaty brown jammy |
Taste Description: at 1.00 - 5.00 ppm. | Musty, vegetative, savory meaty with a brown jammy fullness in the aftertaste Mosciano, Gerard P&F 24, No. 5, 41, (1999) |
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| Odor and/or flavor descriptions from others (if found). |
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| Sigma-Aldrich |
| 2,5-Dimethyl-4-methoxy-3(2H)-furanone, ≥97%, FG |
| Odor Description: | caramel; grape; maple; mushroom; mossy; potato; coffee; nutty; meaty |
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| Firmenich |
| FURANEOL® METHYLETHER Kosher for flavor |
| Taste Description: | Burnt sugar metallic musty raw potato vegetable and bready notes FURANEOL® METHYLETHER brings along with its typical caramelic character, slight meaty and green nuances which work perfectly in strawberry, crab, orange, forest fruits and banana flavors. |
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Cosmetic Information:
Suppliers:
| Advanced Biotech |
| MESIFURAN 20% ETOH NATURAL
Odor: Burnt Sugar |
| Advanced Biotech |
| MESIFURAN 20% IN PG NATURAL
Odor: Burnt sugar |
| Advanced Biotech |
| MESIFURAN 20% IN PG SYNTHETIC
Odor: Burnt sugar |
| Advanced Biotech |
| MESIFURAN SYNTHETIC
98% min. Odor: Burnt sugar |
| Anhui Haibei |
| 4-Methoxy-2,5-dimethyl-3(2H)-furanone
Odor: Sweet mildew moldy maple fruity |
| Augustus Oils |
| 2,5 Dimethyl 4 Methoxy 3 Furanone
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| Services |
| Aurochemicals |
| MESIFURAN 20% IN PG, Natural
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| Beijing Lys Chemicals |
| 2,5-Dimethyl-4-methoxy-2,3-dihydro-furan-3-one
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| BOC Sciences |
| For experimental / research use only. |
| 4-Methoxy-2,5-dimethyl-3(2H)-furanone
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| Carbosynth |
| For experimental / research use only. |
| 4-Methoxy-2,5-dimethyl-3(2H)-furanone
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| Endeavour Specialty Chemicals |
| 4-Methoxy-2,5-dimethyl-3(2H)-furanone
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| Speciality Chemical Product Groups |
| Firmenich |
| FURANEOL® METHYLETHER Kosher
for flavor Flavor: Burnt sugar metallic musty raw potato vegetable and bready notes FURANEOL® METHYLETHER brings along with its typical caramelic character, slight meaty and green nuances which work perfectly in strawberry, crab, orange, forest fruits and banana flavors. |
| H. Interdonati, Inc. |
| Berry Furanone Kosher
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| Featured Products |
| Jiangyin Healthway |
| 4-Methoxy-2.5-dimethyl-3(2H)-furanone
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| New functional food ingredients |
| Lluch Essence |
| FURANEOL METHYL ETHER NATURAL
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| Lluch Essence |
| FURANEOL METHYL ETHER
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| M&U International |
| Fraision Methyl Ether, Kosher
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| Natural Advantage |
| Mesifurane Nat
Flavor: caramellic, fruity, sherry, sweet |
| Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries |
| Penta International |
| 2,5-DIMETHYL-4-METHOXY-3(2H)FURANONE NATURAL
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| Penta International |
| 2,5-DIMETHYL-4-METHOXY-3(2H)FURANONE
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| Phoenix Aromas & Essential Oils |
| Fraision Methyl Ether
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| R C Treatt & Co Ltd |
| 4-Methoxy-2,5-dimethyl-3(2H)furanone
Halal, Kosher |
| Riverside Aromatics |
| 4-METHOXY-2,5-DIMETHYL-3-(2H)-FURANONE, NATURAL
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| Robinson Brothers |
| 4-Methoxy-2,5-dimethyl-3(2H)-furanone F&F
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| https://www.robinsonbrothers.uk/chemistry-competences |
| Sigma-Aldrich |
| 2,5-Dimethyl-4-methoxy-3(2H)-furanone, ≥97%, FG
Odor: caramel; grape; maple; mushroom; mossy; potato; coffee; nutty; meaty |
| Certified Food Grade Products |
| Sigma-Aldrich |
| 2,5-Dimethyl-4-methoxy-3(2H)-furanone, natural, ≥98%, FG
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| Sunaux International |
| Fraision Methyl Ether
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| Synerzine |
| 2,5-Dimethyl-4-methoxy 3(2H) Furanone
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| TCI AMERICA |
| For experimental / research use only. |
| 2,5-Dimethyl-4-methoxy-3(2H)-furanone >97.0%(GC)
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| Tianjin Danjun International |
| 2,5-Dimethyl-4-methoxy-2,3-dihydro-furan-3-one
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| United International |
| 4-Methoxy-2,5-Dimethyl-3(2h)-Furanone
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| WholeChem |
| 2,5-Dimethyl-4-methoxy-2,3-dihydro-furanone
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Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
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| Dermal Toxicity: |
|
Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for strawberry furanone methyl ether usage levels up to: | | | 0.5000 % in the fragrance concentrate.
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| Maximised Survey-derived Daily Intakes (MSDI-EU): | 19.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.70 (μg/capita/day) |
| Structure Class: | II |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 13 |
| Click here to view publication 13 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 12.00000 |
| beverages(nonalcoholic): | - | 0.50000 |
| beverages(alcoholic): | - | 1.00000 |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | 10.00000 |
| condiments / relishes: | - | - |
| confectionery froastings: | - | 2.50000 |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 3.00000 |
| fruit ices: | - | 3.00000 |
| gelatins / puddings: | - | 5.00000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 5.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | 2.50000 |
| meat products: | - | - |
| milk products: | - | 2.50000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | 2.50000 |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 220: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 220, Revision 1 (FGE.220Rev1): alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 220, Revision 2 (FGE.220Rev1): a,ß-Unsaturated ketones and precursors from chemical subgroup 4.4 of FGE.19: 3(2H)-Furanones View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 220 Revision 3 (FGE.220Rev3): Consideration of genotoxic potential for a,ß-unsaturated 3(2H)-Furanones from subgroup 4.4 of FGE.19 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 99 Revision 1 (FGE.99Rev1): Consideration of furanone derivatives evaluated by the JECFA (63rd, 65th and 69th meetings) View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 4077-47-8 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 61325 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | 4-methoxy-2,5-dimethylfuran-3-one |
| Chemidplus: | 0004077478 |
References:
Other Information:
Potential Blenders and core components note
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| For Odor |
| alcoholic |
| alcoholic |
| sec- | hexyl alcohol | FL/FR |
| alliaceous |
| | dimethyl trisulfide | FL/FR |
| amber |
| | labdanum absolute | FL/FR |
| balsamic |
| (E)- | benzyl tiglate | FL/FR |
| burnt |
| (R)-2- | methyl butyraldehyde | |
| buttery |
| | acetoin | FL/FR |
| | caramel pentadione | FL/FR |
| | cyclotene | FL/FR |
| | cyclotene hydrate | FL/FR |
| alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| | ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| | ethyl cyclopentenolone | FL/FR |
| | ethyl maltol | FL/FR |
| 5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
| | fenugreek absolute | FL/FR |
| | fenugreek oleoresin | FL/FR |
| | geranyl crotonate | FR |
| cis-2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | |
| | immortelle absolute | FL/FR |
| | maltol | FL/FR |
| | maltyl propionate | FL/FR |
| | maple furanone | FL/FR |
| | menthone lactone | FL/FR |
| | mesitene lactone | FR |
| | rosefuran | FL/FR |
| | shoyu furanone | FL/FR |
| | strawberry furanone | FL/FR |
| | toffee furanone | FL/FR |
| citrus |
| | methyl heptenone | FL/FR |
| cocoa |
| 2- | methyl butyraldehyde | FL/FR |
| coumarinic |
| | tonka bean resinoid | FR |
| earthy |
| | root fragrance | FR |
| ethereal |
| | acetal | FL/FR |
| iso | valeraldehyde propylene glycol acetal | FL/FR |
| fatty |
| (R)-gamma- | decalactone | FL/FR |
| fruity |
| iso | amyl isovalerate | FL/FR |
| | ethyl (Z)-4-heptenoate | FL/FR |
| (S)-2- | methyl butyraldehyde | |
| 2- | methyl-2-pentenal | FL/FR |
| green |
| 2-sec- | butyl-3-methoxypyrazine | FL/FR |
| 3- | heptanone | FL/FR |
| herbal |
| (S)- | campholene acetate | FL/FR |
| (S)-2- | ethyl hexanoic acid | |
| | trigonella foenum-graecum seed extract | FL/FR |
| nutty |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| | fenugreek resinoid | FL/FR |
| | trigonella foenum-graecum seed oil CO2 extract | FL/FR |
| | furfuryl thioacetate | FL/FR |
| sweet |
| | vanilla oleoresin bali | FL/FR |
| vanilla |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
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| For Flavor |
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| No flavor group found for these |
| 2- | acetyl-3,4,5,6-tetrahydropyridine | FL |
| 2- | acetyl-6-methyl pyrazine | FL |
| | allyl 2-furoate | FL |
| (R)-gamma- | decalactone | FL/FR |
| 2,5- | diethyl tetrahydrofuran | FL |
| alpha,alpha- | dimethyl anisyl acetone | FL/FR |
| | ethyl 2-hydroxy-2-methyl butyrate | FL/FR |
| (S)-2- | ethyl hexanoic acid | |
| 3- | ethyl thiopropanol | FL |
| 5- | ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one | FL/FR |
| sec- | hexyl alcohol | FL/FR |
| cis-2- | hydroxy-3,4,5-trimethyl-2-cyclopenten-1-one | |
| | menthone lactone | FL/FR |
| | methyl 2-hydroxy-4-methyl valerate | FL |
| S- | methyl benzothioate | FL |
| (S)-2- | methyl butyraldehyde | |
| (R)-2- | methyl butyraldehyde | |
| | rosefuran | FL/FR |
| acidic |
| dextro,laevo- | tartaric acid | FL |
| alliaceous |
| | dimethyl trisulfide | FL/FR |
| amber |
| | labdanum absolute | FL/FR |
| balsamic |
| (E)- | benzyl tiglate | FL/FR |
| bready |
| | trigonella foenum-graecum seed extract | FL/FR |
| brown |
| | fenugreek oleoresin | FL/FR |
| burnt |
| | furfuryl alcohol | FL |
| caramellic |
| | caramel dione | FL |
| | caramel furanone | FL |
| | caramel pentadione | FL/FR |
| | cyclotene | FL/FR |
| | cyclotene hydrate | FL/FR |
| | ethyl maltol | FL/FR |
| 5- | ethyl-3,4,5,6-tetramethyl cyclohexen-2-one | FL |
| | fenugreek absolute | FL/FR |
| | fenugreek resinoid | FL/FR |
| | maltol | FL/FR |
| | maltyl propionate | FL/FR |
| | maple furanone | FL/FR |
| | shoyu furanone | FL/FR |
| | strawberry furanone | FL/FR |
| | toffee furanone | FL/FR |
| coffee |
| | coffee distillates | FL |
| creamy |
| | acetoin | FL/FR |
| earthy |
| | panax quinquefolius root extract | FL |
| fatty |
| (E,E)-2,4- | undecadienal | FL |
| 2,4- | undecadienal | FL |
| fruity |
| | ethyl (Z)-4-heptenoate | FL/FR |
| 2- | methyl-2-pentenal | FL/FR |
| 2- | pentanoyl furan | FL |
| iso | valeraldehyde propylene glycol acetal | FL/FR |
| fusel |
| 2- | methyl butyraldehyde | FL/FR |
| green |
| iso | amyl isovalerate | FL/FR |
| | immortelle absolute | FL/FR |
| | methyl heptenone | FL/FR |
| | propylene glycol acetone ketal | FL |
| jammy |
| (S)- | campholene acetate | FL/FR |
| | ethyl cyclopentenolone | FL/FR |
| ketonic |
| 3- | heptanone | FL/FR |
| meaty |
| (R,S)-2- | mercapto-3-butanol | FL |
| musty |
| 2- | ethoxythiazole | FL |
| | propionaldehyde | FL |
| nutty |
| | acetal | FL/FR |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| | aconitic acid | FL |
| | nutty thiazole | FL |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| roasted |
| | furfuryl thioacetate | FL/FR |
| | trigonella foenum-graecum seed oil CO2 extract | FL/FR |
| smoky |
| dextro- | xylose | FL |
| sulfurous |
| | butyl mercaptan | FL |
| | furfuryl thiopropionate | FL |
| 2- | naphthyl mercaptan | FL |
| | potato butanone | FL |
| sweet |
| | vanilla oleoresin bali | FL/FR |
| vanilla |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| vegetable |
| 2-sec- | butyl-3-methoxypyrazine | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | berry furanone | | 2,5- | dimethyl-4-methoxy 3(2H) furanone | | 2,5- | dimethyl-4-methoxy-2,3-dihydro-3-furanone | | 2,5- | dimethyl-4-methoxy-2,3-dihydro-furan-3-one | | 2,5- | dimethyl-4-methoxy-3(2H)-furanone | | 2,5- | dimethyl-4-methoxy-3(2H)furanone | | 2,5- | dimethyl-4-methoxy-3(2H)furanone natural | | 2,5- | dimethyl-4-methoxy-3[2H]-furanone | | 2,5- | dimethyl-4-methoxyfuran-3(2H)-one | | 2,5- | dimethyl-4-methyoxy-2H-furan-3-one | | | fraision methyl ether | | | furaneol methyl ether | | | furaneol methylether (Firmenich) | | 3[2H]- | furanone, 2,5-dimethyl-4-methoxy- | | 3(2H)- | furanone, 4-methoxy-2,5-dimethyl- | | | mesifuran | | | mesifuran 20% in PG natural | | | mesifuran 20% in PG synthetic | | | mesifuran synthetic | | | mesifurane | | 4- | methoxy-2,5-dimethyl-2-hydrofuran-3-one | | 4- | methoxy-2,5-dimethyl-2,3-dihydrofuran-3-one | | 4- | methoxy-2,5-dimethyl-3 2H-furanone | | 4- | methoxy-2,5-dimethyl-3(2H)-furanone | | 4- | methoxy-2,5-dimethyl-3(2H)furanone | | 4- | methoxy-2,5-dimethylfuran-3-one | | 4- | methoxy-2,5-dimethylfuran-3(2H)-one | | | methoxyfuraneol |
Articles:
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