caramel furanone
4,5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
 
Notes:
Can get some extraordinary blends if you shade it well. Key flavour compd. found in raw cane sugar, aged sake, coffee, fenugreek, lovage and wines Sotolon (also known as sotolone) is a lactone and an extremely powerful aroma compound, with the typical smell of fenugreek or curry at high concentrations and maple syrup, caramel, or burnt sugar at lower concentrations. (Wikipedia)
  • Advanced Biotech
    • Advanced Biotech. Inc.
      Inspired by Nature
      A diverse range of products, all meeting our stringent commitment to quality.
      Advanced Biotech is a leading manufacturer and supplier of high-quality Natural flavoring ingredients & botanical extracts for the food/beverage, cosmetic and personal care industries. With over 25 years of experience working with Fermentation processing & botanical extracts, we can help develop new innovative and functional products for today’s competitive marketplace. Our company prides itself in the ability to cater to our customer’s specific needs while maintaining our focus on integrity, honesty and the commitment to high quality product standards. We proudly offer our quality Natural ingredients to companies around the world.
      US Email: Info
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      US Voice: 973-339-6242
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      Product(s):
      2079 CARAMEL FURANONE SYNTHETIC 97% min.
      SDS
       
  • Anhui Primechem
    • Anhui Primechem Co., Ltd.
      Where Scent Matters Most
      Dependable supply and professional services to exceed our client's expectations.
      For over 2 decades, Primechem has proven to be a professional and outstanding supplier, offering a diverse range of superior quality products, services and solutions for use in Flavor & Fragrances industries worldwide.
      Email: Info
      Email: Sales
      Voice: +86-551-628 355 29
      Fax: :+86-551-628 330 59
      News and Events
      At a glance
      Products List: View
      Product(s):
      Sugar Lactone
       
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
      Email: Enquiries
      Email: Sales
      Email: web site enquiries
      Voice: +44 (0)1420 590555
      Fax: +44 (0)1420 592420
      Services
      Product(s):
      Fenugreek Lactone
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
      Email: Mr. Guo
      Voice: 86-10-68418738
      Fax: 86-10-68418739
      Mr. Guo86-10-68483445
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      News
      Product(s):
      10269 Caramel furanone
       
  • Berjé
    • Berje Inc.
      Where the world comes to its senses
      Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.
      Berjé is a family-owned business that has been in operation for six decades. The company's origins and strength lie in a profound understanding of the supply and the quality of the diverse raw materials consumed by the flavor and fragrance industries. This base was expanded upon more than two decades ago to include fragrance production. The company's unparalleled raw material expertise is focused on the supply of essential oils and aromatic chemicals. This is supported by our long-standing relationships with a worldwide fabric of producers ensuring the greatest prospects for uninterrupted supply in markets that are often volatile and unpredictable.
      Email: For Information
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      Voice: 973-748-8980
      Fax: 973-680-9618
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      Products List: View
      Product(s):
      Caramel Furanone 100%
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
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      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
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      Europe44-203-286-1088
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      Product(s):
      28664-35-9 CARAMEL FURANONE (3% IN TRIACETIN)
       
  • Excellentia International
  • H. Interdonati, Inc.
    • H. Interdonati, Inc.
      Innovative products
      Because your flavors and fragrances are only as good as their source "Since 1952"
      H. Interdonati, Inc. began in 1952 with the tradition of delivering quality pharmaceuticals and fine chemical ingredients at competitive prices. The mission was simple: To provide the most reliable, personal service in the industry.
      Email: Info
      US Email: Info
      Email: Sales
      US Email: Laura Interdonati (Sales)
      Voice: 800 367-6617
      Fax: 631 367-6626
      Featured Products
      Product(s):
      Caramel Furanone Kosher
       
  • Frutarom
    • FRUTAROM USA INC,
      Flavor & Specialty Ingredients
      Your preferred partner for flavour and fragrance success.
      Our broad and diverse product portfolio is designed to provide and cater for every flavor and taste profile required by our customer base and incorporates historic, and iconic, market leading products.
      Email: Info
      US Email: Info- USA
      Email: Sales
      Voice: +44 (0) 1429 863 222
      Products List: View
      Product(s):
      3304286001 4-5-DIMETHYL 3 HYDROXY FURANONE KOSHER
       
  • Lluch Essence
    • Lluch Essence S.L.
      A family company dedicated to sales and distribution
      Flexibility, availability, price and quality.
      Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world.
      Email: Info
      Voice: 34 93 379 38 49
      Fax: 34 93 370 65 04
      Linkedin
      Product(s):
      SUGAR LACTONE
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
      News
      Product(s):
      A0044B Fenugreek Lactone, Kosher
      A0247 Sotolone, Kosher
      N0166 NAT.FENUGREEK LACTONE
       
  • Moellhausen
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
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      US Voice: (973) 740-2300
      US Fax: (973) 740-1839
      Product(s):
      03-09290 CARAMEL FURANONE PURE
      03-09295 CARAMEL FURANONE NATURAL NEAT
       
  • Riverside Aromatics
    • Riverside Aromatics Ltd.
      Speciality Aroma Chemicals, Naturals and Synthetics
      A specialist supplier of raw materials to the flavour industry.
      Peter Cannon & David Rowe established Riverside Aromatics in 2006 in Poole, UK, to offer a new type of specialist raw material supplier to the Flavour & Fragrance Industry. We bring together over 40 years of commercial & technical experience in the F&F industry which allows us to understand the needs of the Global F&F business and especially that of the West European Market.
      Email: Info
      Email: Peter Cannon (sales)
      Voice: +44 (0) 1202 679532
      Fax: +44 (0) 1202 679532
      Products List: View
      Product(s):
      DF1000 FENUGREEK LACTONE [SOTOLONE]
       
  • Robertet
    • Robertet, Inc.
      HOME OF NATURE, SEED TO SCENT
      HOME OF NATURE – natural ingredients from the source.
      Robertet is a leader in the production of natural ingredients with facilities in France, Bulgaria, Turkey, South Africa, India, China, New Caledonia,… Founded in 1850, Robertet remains a family owned business (5th Generation) and one of the largest producers of aromatic extracts. Brand acquisitions include: Charabot, Sapad, Hitex.
      US Email: Customer service
      US Email: Arnaud Adrian
      Email: Flavor:
      Email: Fragrance:
      Voice: 33 4 93 40 33 66
      Fax: 33 4 93 70 68 09
      US Voice: +1.201.337.7100
      +1 212 710 4600Robertet New York Creative Center
      +1 212 245 4092Robertet New York Creative Center
      Facebook
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      Crop Calendar
      Seasons and Harvest / Crop calendar
      Product(s):
      102901 Sotolone
       
  • Sigma-Aldrich
  • Soda Aromatic
    • Soda Aromatic Co., Ltd.
      Depth of Experience
      We guarantees product safety and quality.
      Our international sales department is happy to design the most suitable flavor & fragrance for specific uses of processed food, cosmetics, and fragrance manufactures all over the world, specializing in Asia.Let us help you with your flavor & fragrance needs.
      Email: Info
      Email: Sales
      Voice: +81-3-5645-7347
      Fax: +81-3-3664-5204
      Product(s):
      110204051 Sugar Lactone
       
  • SRS Aromatics
    • SRS Aromatics Ltd
      For over 25 years
      Bringing flavour and fragrance into your world.
      As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply.
      Email: Info
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      Voice: +44 (0) 1284 704076
      Fax: +44 (0) 1284 760819
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      Product(s):
      SUGAR LACTONE PURE
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
      US Email: Customer Service
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      Product(s):
      W0435N 4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE CARAMEL FURANONE, NATURAL
      W0435P CARAMEL FURANONE
       
  • Tianjin Danjun International
    • Tianjin Danjun International Trade Co., LTD.
      Quality Products
      We know the Chinese chemical market well.
      Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
      Email: Info
      Email: Sales
      Voice: +86-15822601686
      Products List: View
      Product(s):
      B-065 Caramel furanone
       
Synonyms   Articles   Notes   Search
    Flavor Demo Formulas
CAS Number: 28664-35-9Picture of molecule3D/inchi
Other(deleted CASRN): 87021-36-1
ECHA EINECS - REACH Pre-Reg: 249-136-4
FDA UNII: T62RL2NEGW
Nikkaji Web: J68.557G
MDL: MFCD00059957
CoE Number: 11834
XlogP3-AA: 0.40 (est)
Molecular Weight: 128.12736000
Formula: C6 H8 O3
NMR Predictor: Predict (works with chrome, Edge or firefox)
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 243  4,5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
DG SANTE Food Flavourings: 10.030  3-hydroxy-4,5-dimethylfuran-2(5H)-one
FEMA Number: 3634 4,5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
FDA:No longer provide for the use of these seven synthetic flavoring substances
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white to pale yellow liquid to solid (est)
Assay: 97.50 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 25.00 to  29.00 °C. @ 760.00 mm Hg
Boiling Point: 93.00 to  95.00 °C. @ 2.00 mm Hg
Boiling Point: 81.00 °C. @ 6.00 mm Hg
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): -0.296 (est)
Soluble in:
 alcohol
 water, 2.228e+005 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 alcoholic fine fragrance, good
 antiperspirant, fair
 fabric softener, fair
 hypochlorite bleach, poor
 liquid detergent, fair
 perborate powder detergent, poor
 soap, fair
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: caramellic
 
Odor Strength: very high ,
recommend smelling in a 0.01 % solution or less
 
Substantivity: > 400 hour(s) at 3.00 % in propylene glycol
 
 sweet  caramellic  maple  sugar burnt sugar  coffee  
Odor Description:
at 0.01 % in propylene glycol. 
extremely sweet strong caramel maple burnt sugar coffee
Luebke, William tgsc, (1998)
 
 sweet  caramellic  maple  sugar brown sugar  cotton candy  
Odor Description:
Sweet, caramellic, maple, brown sugar, cyclotene and cotton candy
Mosciano, Gerard P&F 22, No. 4, 75, (1997)
 
 
Flavor Type: caramellic
 
 sweet  maple  sugar brown sugar  cotton candy  sugar burnt sugar  
Taste Description:
sweet maple brown sugar cotton candy burnt sugar
Luebke, William tgsc, (1998)
 
 sweet  caramellic  maple  sugar brown sugar  cotton candy  
Taste Description:
at 50.00 ppm.  
Sweet, caramellic, maple, brown sugary and cotton candy
Mosciano, Gerard P&F 22, No. 4, 75, (1997)
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
Advanced Biotech
CARAMEL FURANONE SYNTHETIC
97% min.
Odor: Caramel, Sweet
Anhui Haibei
3-Hydroxy-4,5-dimethyl-2(5H)-furanone
Odor: Extremely sweet strong caramel maple burnt sugar coffee
Anhui Primechem
Sugar Lactone
Aromiens International
Caramel Furanone Natural
Aromiens International
Caramel Furanone
Artiste
Caramel Furanone Natural
Available as solutions (1%, 5%, 15%, etc.) in various solvents.
Augustus Oils
Fenugreek Lactone
Services
Aurochemicals
FENUGREEK LACTONE, Natural
Beijing Lys Chemicals
Caramel furanone
Berjé
Caramel Furanone 100%
Media
BOC Sciences
For experimental / research use only.
CARAMEL FURANONE (3% IN TRIACETIN)
DeLong Chemicals America
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
Ernesto Ventós
4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE NATURAL
Excellentia International
Caramel Furanone (4,5-Dimethyl-3-Hydroxy-2(5H)-Furanone) Natural
Frutarom
4-5-DIMETHYL 3 HYDROXY FURANONE
KOSHER
Flavor: Sweet, Caramellic, Maple, Sugar, Burnt
H. Interdonati, Inc.
Caramel Furanone Kosher
Featured Products
IFF
4-5-DIMETHYL 3 HYDROXY FURANONE
KOSHER
Flavor: Sweet, Caramellic, Maple, Sugar, Burnt
Kun Shan P&A
Caramel Furanone
Lluch Essence
SUGAR LACTONE
M&U International
Fenugreek Lactone, Kosher
M&U International
NAT.FENUGREEK LACTONE
M&U International
Sotolone, Kosher
Moellhausen
SOTOLON
Penta International
CARAMEL FURANONE NATURAL NEAT
Penta International
CARAMEL FURANONE PURE
Phoenix Aromas & Essential Oils
Caramel Furanone (all solutions)
R C Treatt & Co Ltd
4-Methoxy-2,5-dimethyl-3(2H)furanone
Reincke & Fichtner
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
Riverside Aromatics
FENUGREEK LACTONE [SOTOLONE]
Robertet
Sotolone
Seasons and Harvest / Crop calendar
Sigma-Aldrich
4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one, ≥97%, FG
Odor: caramel; celery; maple; tobacco; earthy; green; meaty; wine-like; nutty; seedy; smoky
Certified Food Grade Products
Soda Aromatic
Sugar Lactone
Odor: very powerful, roasted sugar-like
SRS Aromatics
SUGAR LACTONE PURE
Synerzine
4,5-DIMETHYL-3-HYDROXY-2,5-DIHYDROFURAN-2-ONE CARAMEL FURANONE, NATURAL
Synerzine
CARAMEL FURANONE
Tengzhou Xiang Yuan Aroma Chemicals
4,5-Dimethyl-3-hydroxy-2,5H-furanone
Tianjin Danjun International
Caramel furanone
United International
Sugar lactone
Vigon International
Fenugreek Lactone (Sotolone)
Odor: Extremely Strong,Fenugreek,Lovage,Maple
Vigon International
Sotolone Natural (dimethyl Oxyfurone)
WholeChem
Fenugreek Lactone
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 20/22 - Harmful by inhalation and if swallowed.
R 36/37 - Irritating to eyes and respiratory system.
S 02 - Keep out of the reach of children.
S 07 - Keep container tightly closed.
S 09 - Keep container in a well-ventilated place.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 35 - This material and its container must be disposed of in a safe way.
S 36 - Wear suitable protective clothing.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 46 - If swallowed, seek medical advice immediately and show this container or label.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavoring agents
Recommendation for caramel furanone usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 1.80 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 0.10 (μg/capita/day)
Structure Class: III
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 12. Update in publication number(s): 29
Click here to view publication 12
 average usual ppmaverage maximum ppm
baked goods: 10.0000020.00000
beverages(nonalcoholic): --
beverages(alcoholic): 0.010005.00000
breakfast cereal: --
cheese: --
chewing gum: 1.000005.00000
condiments / relishes: 2.5000010.00000
confectionery froastings: --
egg products: --
fats / oils: 0.1000010.00000
fish products: 2.0000010.00000
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 2.0000010.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 2.0000010.00000
milk products: --
nut products: --
other grains: --
poultry: 2.0000010.00000
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 0.1000020.00000
snack foods: --
soft candy: --
soups: 2.0000010.00000
sugar substitutes: --
sweet sauces: 2.5000010.00000
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of lactones used as flavor ingredients. View pdf
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab)
View page or View pdf
Flavouring Group Evaluation 217: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones[1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones
View page or View pdf
Scientific Opinion on the safety and efficacy of furanones and tetrahydrofurfuryl derivatives: 5-ethyl-3-hydroxy-4-methylfuran-2(5H)-one and 3-hydroxy-4,5-dimethylfuran-2(5H)-one (chemical group 13) when used as flavourings for all animal species
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 217 Revision 2 (FGE.217Rev2), consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 28664-35-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 62835
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 3-hydroxy-4,5-dimethyl-5H-furan-2-one
Chemidplus: 0028664359
Synonyms   Articles   Notes   Search   Top
References:
Leffingwell: Chirality or Article
 3-hydroxy-4,5-dimethyl-5H-furan-2-one
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 28664-35-9
Pubchem (cid): 62835
Pubchem (sid): 135021025
Flavornet: 28664-35-9
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB31306
FooDB: FDB003360
YMDB (Yeast Metabolome Database): YMDB01572
Export Tariff Code: 2905.32.0000
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
acidic
acidic
 cyclohexyl acetic acidFL/FR
balsamic
2-acetyl furanFL/FR
 benzyl salicylateFL/FR
3-phenyl propyl alcoholFL/FR
berry
 raspberry ketoneFL/FR
bready
 coffee furanoneFL/FR
buttery
 acetoinFL/FR
 acetyl propionylFL/FR
3,4-hexane dioneFL/FR
2-isobutyl-3-methyl pyrazineFL/FR
2-oxobutyric acidFL/FR
 caramel furanone solutionFL/FR
 caramel pentadioneFL/FR
 coffee dioneFL/FR
 cycloteneFL/FR
 cyclotene hydrateFL/FR
 diethyl malateFL/FR
alpha,alpha-dimethyl anisyl acetoneFL/FR
 ethyl 2-hydroxy-2-methyl butyrateFL/FR
 ethyl cyclopentenoloneFL/FR
 ethyl furaneolFL/FR
 ethyl maltolFL/FR
5-ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-oneFL/FR
 fenugreek absoluteFL/FR
 fenugreek oleoresinFL/FR
 immortelle absoluteFL/FR
 levulinic acidFL/FR
 maltolFL/FR
 maltyl propionateFL/FR
 maple furanoneFL/FR
 menthone lactoneFL/FR
5-methyl furfuralFL/FR
isopropenyl pyrazineFL/FR
 rosefuranFL/FR
 shoyu furanoneFL/FR
 strawberry furanoneFL/FR
 strawberry furanone acetateFL/FR
 strawberry furanone solutionFL/FR
 toffee furanoneFL/FR
chocolate
2,4,5-trimethyl thiazoleFL/FR
citrus
blood orange oil italyFL/FR
coconut
gamma-heptalactoneFL/FR
gamma-octalactoneFL/FR
creamy
gamma-butyrolactoneFL/FR
ethereal
 ethyl 4-pentenoateFL/FR
 ethyl pyruvateFL/FR
isovaleraldehyde propylene glycol acetalFL/FR
fermented
 ethyl (E)-2-crotonateFL/FR
floral
beta-damascenoneFL/FR
 ethyl phenyl acetateFL/FR
 heliotropinFL/FR
 heliotropyl acetoneFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 methyl dihydrojasmonateFL/FR
 mimosa absolute franceFL/FR
 nerolidolFL/FR
 ocean propanalFL/FR
fruity
beta-damasconeFL/FR
gamma-decalactoneFL/FR
(E)-ethyl tiglateFL/FR
 osmanthus flower absoluteFL/FR
 tetrahydrofurfuryl acetateFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
green
isoamyl 3-(2-furan) propionateFL/FR
 methyl octine carbonateFL/FR
(E,Z)-2,6-nonadien-1-olFL/FR
 violet leaf absoluteFL/FR
hay
 beeswax absoluteFL/FR
herbal
 butyl levulinateFL/FR
3-propylidene phthalideFL/FR
honey
 methyl phenyl acetateFL/FR
melon
 melon heptenalFL/FR
(Z)-6-nonenalFL/FR
moldy
 strawberry furanone methyl etherFL/FR
musty
3-acetyl-2,5-dimethyl furanFL/FR
nutty
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
1,2-cyclohexane dioneFL/FR
2,3-dimethyl pyrazineFL/FR
 nutty cyclohexenoneFL/FR
phenolic
4-methyl-2,6-dimethoxyphenolFL/FR
popcorn
2-acetyl pyrazineFL/FR
2-acetyl pyridineFL/FR
powdery
para-anisyl acetateFL/FR
 fenugreek resinoidFL/FR
spicy
 cassia bark oil chinaFL/FR
black currant bud absoluteFL/FR
isoeugenyl acetateFL/FR
(E)-tiglic acidFL/FR
sweet
2-hydroxy-3,4,5-trimethyl-2-cyclopenten-1-oneFL/FR
 vanilla oleoresin baliFL/FR
vanilla
 ethyl vanillinFL/FR
 vanillinFL/FR
 vanillyl isobutyrateFL/FR
vegetable
 tetrahydrofurfuryl alcoholFL/FR
 
For Flavor
 
No flavor group found for these
2-acetyl-3,4,5,6-tetrahydropyridineFL
 allyl 2-furoateFL
 benzyl disulfideFL
1,2-cyclohexane dioneFL/FR
 diethyl malateFL/FR
2,5-diethyl tetrahydrofuranFL
alpha,alpha-dimethyl anisyl acetoneFL/FR
 ethyl 2-hydroxy-2-methyl butyrateFL/FR
 ethyl 4-pentenoateFL/FR
5-ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-oneFL/FR
 furfuryl acetoneFL
2-hydroxy-3,4,5-trimethyl-2-cyclopenten-1-oneFL/FR
 menthone lactoneFL/FR
 rosefuranFL/FR
isoamyl 3-(2-furan) propionateFL/FR
beta-damasconeFL/FR
acidic
 levulinic acidFL/FR
dextro,laevo-tartaric acidFL
apple
(E,Z)-2,6-nonadien-1-olFL/FR
balsamic
 benzyl salicylateFL/FR
berry
 heliotropyl acetoneFL/FR
 raspberry ketoneFL/FR
bready
 mango furanoneFL
brown
 beeswax absoluteFL/FR
2-oxobutyric acidFL/FR
 fenugreek oleoresinFL/FR
5-methyl furfuralFL/FR
 tetrahydrofurfuryl acetateFL/FR
(E)-tiglic acidFL/FR
burnt
 furfuryl alcoholFL
isopropenyl pyrazineFL/FR
buttery
 butter brickle flavorFL
 butter maple flavorFL
 diacetylFL
3,4-hexane dioneFL/FR
caramellic
 butterscotch flavorFL
 caramel dioneFL
 caramel furanone solutionFL/FR
 caramel pentadioneFL/FR
 cycloteneFL/FR
 cyclotene hydrateFL/FR
 ethyl furaneolFL/FR
 ethyl maltolFL/FR
5-ethyl-3,4,5,6-tetramethyl cyclohexen-2-oneFL
 fenugreek absoluteFL/FR
 fenugreek resinoidFL/FR
 honey maple flavorFL
 lucuma flavorFL
 maltolFL/FR
 maltyl propionateFL/FR
 maple furanoneFL/FR
3-methyl butyl 2-furyl butyrateFL
 pyruvaldehydeFL
 shoyu furanoneFL/FR
 strawberry furanoneFL/FR
 strawberry furanone acetateFL/FR
 strawberry furanone solutionFL/FR
 toffee furanoneFL/FR
cherry
 heliotropinFL/FR
citrus
blood orange oil italyFL/FR
coffee
 coffee dioneFL/FR
2-thiophene thiolFL
corn
2-acetyl pyridineFL/FR
2-acetyl-2-thiazolineFL
creamy
 acetoinFL/FR
 marshmallow flavorFL
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
fatty
(E,E)-2,4-undecadienalFL
2,4-undecadienalFL
floral
 methyl dihydrojasmonateFL/FR
 methyl phenyl acetateFL/FR
 ocean propanalFL/FR
fruity
para-anisyl acetateFL/FR
 date flavorFL
gamma-decalactoneFL/FR
(E)-ethyl tiglateFL/FR
 furfuryl valerateFL
 osmanthus flower absoluteFL/FR
2-pentanoyl furanFL
isovaleraldehyde propylene glycol acetalFL/FR
green
2-isobutyl-3-methyl pyrazineFL/FR
 immortelle absoluteFL/FR
 melon heptenalFL/FR
 methyl octine carbonateFL/FR
 nerolidolFL/FR
(Z)-6-nonenalFL/FR
3-propylidene phthalideFL/FR
 violet leaf absoluteFL/FR
herbal
 butyl levulinateFL/FR
5-hydroxymethyl furfuralFL
honey
 ethyl phenyl acetateFL/FR
jammy
 ethyl cyclopentenoloneFL/FR
lactonic
gamma-heptalactoneFL/FR
gamma-octalactoneFL/FR
meaty
maple bacon flavorFL
2-mercaptomethyl pyrazineFL
milky
gamma-butyrolactoneFL/FR
moldy
 strawberry furanone methyl etherFL/FR
musty
 ethyl (E)-2-crotonateFL/FR
nutty
2-acetyl furanFL/FR
3-acetyl-2,5-dimethyl furanFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
3,5(6)-cocoa pyrazineFL
 coffee furanoneFL/FR
2,3-dimethyl pyrazineFL/FR
 nutty cyclohexenoneFL/FR
 peanut oxazoleFL
 tetrahydrofurfuryl alcoholFL/FR
2,4,5-trimethyl thiazoleFL/FR
phenolic
4-methyl-2,6-dimethoxyphenolFL/FR
roasted
2-acetyl pyrazineFL/FR
rummy
 ethyl pyruvateFL/FR
spicy
 cassia bark oil chinaFL/FR
black currant bud absoluteFL/FR
isoeugenyl acetateFL/FR
3-phenyl propyl alcoholFL/FR
sugar
 cotton candy flavorFL
sweet
 cyclohexyl acetic acidFL/FR
 dulce de leche flavorFL
 molasses flavorFL
dextro-sorbitolFL
 vanilla oleoresin baliFL/FR
toasted
 acetyl propionylFL/FR
vanilla
 ethyl vanillinFL/FR
 vanillinFL/FR
 vanillyl isobutyrateFL/FR
waxy
 furfuryl octanoateFL
alpha-hexyl cinnamaldehydeFL/FR
 mimosa absolute franceFL/FR
woody
beta-damascenoneFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 allspiceFL
 bananaFL
 bay rumFR
 blackberryFL
 butterscotchFL
 caramelFL
 cinnamonFL
 coconutFL
 coffeeFL
 cotton candyFL
 cranberryFL
 fenugreekFL/FR
 figFL
 fir 
 fir balsamFR
 gingerbreadFR
 honeysuckleFR
 mangoFL
 mapleFL
 melonFL
 mulberryFL
 muskFR
 nutFL
 papayaFL
 passion fruitFR
 peachFL
 pina coladaFL
 pineappleFL
 pomegranateFL
 pumpkinFL
 sugar brown sugarFL
 tobaccoFR
 toffeeFL
 tonka beanFR
 vanillaFL
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 coffee
Search  PMC Picture
 fenugreek seed
Search Trop  Picture
 honey buckwheat honey
PbMd  Search  PMC Picture
 maple
Search  PMC Picture
 pineapple fruit
Search Trop  Picture
 sake
Search  PMC Picture
 sherry
Search  PMC Picture
 tobacco virginia tobacco
Search  Picture
 wine rice wine
Search  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 caramel furanone 100%
 caramel furanone natural
 caramel furanone pure
 caramel furanone synthetic
 caramel furanone, neat
 caramel lactone
 dimethyl oxyfurone
4,5-dimethyl-3-hydroxy-2,5-dihydro-2-furanone
4,5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one
4,5-dimethyl-3-hydroxy-2(5H)-furanone
2,3-dimethyl-4-hydroxy-2,5-dihydrofuran-5-one
 fenugreek lactone
2-hydroxy-3-methyl-2-penten-4-olide
2-hydroxy-3,4-dimethyl-2-buten-1,4-olide
3-hydroxy-4,5-dimethyl furan-2(5H)-one
3-hydroxy-4,5-dimethyl-2(5H)-furanone
3-hydroxy-4,5-dimethyl-5-hydrofuran-2-one
3-hydroxy-4,5-dimethyl-5H-furan-2-one
3-hydroxy-4,5-dimethylfuran-2(5H)-one
 soloton
 sotolon (Givaudan)
 sotolone
 sugar lactone
Synonyms   Articles   Notes   Search   Top
Articles:
US Patents: 4,428,886 - Novel intermediates for the preparation of .alpha.-hydroxycarbonyl compounds
PubMed: UHPLC quantification of sotolon in white wine.
PubMed: Milk volatile organic compounds and fatty acid profile in cows fed timothy as hay, pasture, or silage.
PubMed: Protective effect of Trigonella foenum-graecum Linn. on monosodium glutamate-induced dyslipidemia and oxidative stress in rats.
PubMed: Effect of grain type and toasting conditions of barrels on the concentration of the volatile substances released by the wood and on the sensory characteristics of Montepulciano d'Abruzzo.
PubMed: Analytical characterization of the aroma of five premium red wines. Insights into the role of odor families and the concept of fruitiness of wines.
PubMed: Characterization of odor-active compounds in Californian chardonnay wines using GC-olfactometry and GC-mass spectrometry.
PubMed: 4-Hydroxyisoleucine: effects of synthetic and natural analogues on insulin secretion.
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