|
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 98.00 to 100.00 %
|
| Additional Assay Information: | sum of 2,3- 2,5- and 2,6- isomers |
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 0.98000 to 1.00000 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 8.155 to 8.321
|
| Refractive Index: | 1.49700 to 1.50100 @ 20.00 °C.
|
| Melting Point: | 15.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 154.00 to 156.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 3.980000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 3.7 ( Air = 1 ) |
| Flash Point: | 130.00 °F. TCC ( 54.44 °C. )
|
| logP (o/w): | 0.630 |
| Soluble in: |
| | alcohol | | | water, 3.197e+004 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: chocolate |
| |
| | cocoa roasted nutty beefy roasted beefy woody grassy medicinal |
Odor Description: at 0.10 % in dipropylene glycol. | cocoa roasted nuts roast beef woody grass medical |
| |
| | nutty peanut musty earthy powdery roasted cocoa |
Odor Description:
| Nutty, peanut, musty, earthy, powdery and slightly roasted with a cocoa powder nuance Mosciano, Gerard P&F 21, No. 6, 49, (1996) |
| |
| |
| Flavor Type: musty |
| |
| | musty potato cocoa nutty fatty oily |
Taste Description: at 7.50 ppm. | Musty, potato, cocoa and nutty with a fatty and oily nuance Mosciano, Gerard P&F 21, No. 6, 49, (1996) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| Bedoukian Research |
| 2,5-DIMETHYL PYRAZINE ≥99.0%, Kosher |
| Odor Description: | cocoa, roasted nut, roast beef, woody Could be used very sparingly in appropriate applications. |
| Taste Description: | cocoa Used in potato, beer and chicken flavors as well as those needing fried notes. |
| |
| Kingchem Laboratories |
| 2, 5 DIMETHYLPYRAZINE |
| Odor Description: | Roast, coffee, peanut and meat |
| |
| Advanced Biotech |
| 2,5 DIMETHYL PYRAZINE NATURAL 90% min. (mixed isomers) |
| Odor Description: | Chocolate, roasted nuts |
| |
| Advanced Biotech |
| 2,5 DIMETHYL PYRAZINE |
| Odor Description: | Chocolate, Nutty, Roasted |
| |
| Pell Wall Perfumes |
| Ketine (Pyrazine) |
| Odor Description: | chocolate, cocoa, roasted-nuts, woody, slightly green-grass According to Arctander the main use of this material was to scent the packets and enhance the flavour of potato crisps / chips.
It is present in the scent of coffee and chocolate but also some types of lavender, beer and pork. It also has a green-grass aspect that can add depth to green scents, in high dilution. |
| |
| Advanced Biotech |
| 2 5 DIMETHYL PYRAZINE (W TYPE) NATURAL |
| Odor Description: | Chocolate, Roasted Nut |
| |
| |
Cosmetic Information:
Suppliers:
| Advanced Biotech |
| 2 5 DIMETHYL PYRAZINE (W TYPE) NATURAL
Odor: Chocolate, Roasted Nut |
| Advanced Biotech |
| 2,5 DIMETHYL PYRAZINE NATURAL
90% min. (mixed isomers) Odor: Chocolate, roasted nuts |
| Advanced Biotech |
| 2,5 DIMETHYL PYRAZINE
Odor: Chocolate, Nutty, Roasted |
| Advanced Biotech |
| 2,5(6) DIMETHYL PYRAZINE NATURAL
|
| Ambles Nature et Chimie |
| 2.5 DIMETHYL NAT
|
| Anhui Haibei |
| 2,5-Dimethyl Pyrazine
Odor: Cocoa roasted nuts roast beef woody grass medical |
| Augustus Oils |
| 2,5 Dimethyl Pyrazine
|
| Services |
| Beijing Lys Chemicals |
| 2,5-Dimethyl pyrazine
|
| BOC Sciences |
| For experimental / research use only. |
| 2,5-Dimethylpyrazine
|
| Charkit Chemical |
| DIMETHYLPYRAZINE, 2,5- FEMA 3272
|
| CJ Latta & Associates |
| 2,5-DIMETHYL PYRAZINE
|
| DeLong Chemicals America |
| 2,5-Dimethylpyrazine, Kosher
|
| Diffusions Aromatiques |
| 2,5-DIMETHYL PYRAZINE
|
| EMD Millipore |
| For experimental / research use only. |
| 2,5-Dimethylpyrazine
|
| Endeavour Specialty Chemicals |
| 2,5-Dimethyl pyrazine
|
| Speciality Chemical Product Groups |
| Ernesto Ventós |
| 2,5-DIMETHYLPYRAZINE
Odor: RAW POTATO, ROASTED, EARTHY |
| Excellentia International |
| 2,5-Dimethyl Pyrazine (Pyrazine Mix. # 10, 12, 16, 20) Natural
|
| FCI SAS |
| 2,5-DIMETHYL PYRAZINE
Odor: Roast, coffee, peanut and meat |
| Fleurchem |
| 2,5-dimethyl pyrazine
|
| Fleurchem |
| dimethyl pyrazine natural
|
| Frutarom |
| 2,5-DIMETHYLPYRAZINE
KOSHER Flavor: Musty, Oily, Nutty, Roasted |
| CBD Offering |
| IFF |
| 2,5-DIMETHYLPYRAZINE
KOSHER Flavor: Musty, Oily, Nutty, Roasted |
| Indukern F&F |
| 2,5-DIMETHYL PYRAZINE
Odor: EARTHY, POTATO |
| Jiangyin Healthway |
| 2,5-Dimethyl Pyrazine
|
| New functional food ingredients |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| 2,5-Dimethyl pyrazine, Kosherk
|
| Kingchem Laboratories |
| 2, 5 DIMETHYLPYRAZINE
Odor: Roast, coffee, peanut and meat |
| Lluch Essence |
| PYRAZINE 2,5-DIMETHYL
|
| M&U International |
| 2,5-DIMETHYL PYRAZINE, Kosher
|
| M&U International |
| Nat. 2,5-Dimethyl Pyrazine
|
| Moellhausen |
| 2,5-DIMETHYL PYRAZINE (10%DPG)
|
| Moellhausen |
| 2,5-DIMETHYL PYRAZINE
Odor: coffee, nut, cocoa Flavor: nut, fat, cocoa, potato |
| Myrazine |
| 2,5-Dimethylpyrazine/EU Nat.
Odor: cocoa roasted nuts roast beef woody grass medical |
| Myrazine |
| Pyrazine, 2,5-dimethyl-
Odor: cocoa roasted nuts roast beef woody grass medical |
| OQEMA |
| 2,5-Dimethyl Pyrazine
|
| Pearlchem Corporation |
| 2,5-Dimethyl Pyrazine
|
| Pell Wall Perfumes |
| Ketine (Pyrazine)
Odor: chocolate, cocoa, roasted-nuts, woody, slightly green-grass Use: According to Arctander the main use of this material was to scent the packets and enhance the flavour of potato crisps / chips.
It is present in the scent of coffee and chocolate but also some types of lavender, beer and pork. It also has a green-grass aspect that can add depth to green scents, in high dilution. |
| Penta International |
| 2,5-DIMETHYL PYRAZINE NATURAL
|
| Penta International |
| 2,5-DIMETHYL PYRAZINE
|
| Phoenix Aromas & Essential Oils |
| Pyrazine, 2,5-Dimethyl
|
| R C Treatt & Co Ltd |
| 2,5-Dimethylpyrazine
Halal, Kosher |
| Reincke & Fichtner |
| 2,5-Dimethylpyrazine
|
| Riverside Aromatics |
| 2,5-DIMETHYLPYRAZINE
|
| Robinson Brothers |
| 2,5-Dimethyl pyrazine F&F
|
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 2,5-Dimethylpyrazine
|
| Sigma-Aldrich |
| 2,5-Dimethylpyrazine, ≥98%, FCC, FG
Odor: meaty; medicinal; nutty; woody. |
| Certified Food Grade Products |
| Sunaux International |
| 2,5-Dimethyl Pyrazine
|
| Synerzine |
| 2,5-DIMETHYLPYRAZINE MIXTURE (NATU
|
| Synerzine |
| 2,5-Dimethylpyrazine
97% min (Flavor grade) |
| Synerzine |
| 2,5-Dimethylpyrazine
99% min (Research grade) |
| Synerzine |
| natural 2,5-Dimethylpyrazine
|
| Taytonn ASCC |
| 2,5-Dimethylpyrazine
Odor: Grass, Green, Nutty, Roast, Woody |
| TCI AMERICA |
| For experimental / research use only. |
| 2,5-Dimethylpyrazine >98.0%(GC)(T)
|
| Tengzhou Jitian Aroma Chemiclal |
| 2,5-Dimethyl Pyrazine
|
| Tengzhou Xiang Yuan Aroma Chemicals |
| 2,5-Dimethyl Pyrazine
|
| Tianjin Danjun International |
| 2,5-Dimethylpyrazine
|
| United International |
| 2,5-Dimethyl Pyrazine Nat.
|
| United International |
| 2,5-Dimethyl Pyrazine
|
| Vigon International |
| DIMETHYL-2,5 PYRAZINE NATURAL
|
| Vigon International |
| Dimethyl-2,5 Pyrazine
|
| WholeChem |
| 2.5-Dimethyl pyrazine
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 22 - Harmful if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
gavage-rat LD50 1020 mg/kg (Moran et al., 1980)
intraperitoneal-mouse LD50 1350 mg/kg Toxicology and Applied Pharmacology. Vol. 17, Pg. 244, 1970.
oral-rat LD50 1020 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for 2,5-dimethyl pyrazine usage levels up to: | | | 0.1000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 19.00 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 8.00 (μg/capita/day) |
| Structure Class: | II |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 5 |
| Click here to view publication 5 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 10.00000 |
| beverages(nonalcoholic): | - | 10.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | 10.00000 |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 10.00000 |
| fruit ices: | - | 10.00000 |
| gelatins / puddings: | - | 10.00000 |
| granulated sugar: | - | - |
| gravies: | - | 10.00000 |
| hard candy: | - | 10.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 10.00000 |
| milk products: | - | 10.00000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | 10.00000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): |
| The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf |
Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species View page or View pdf |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 123-32-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 31252 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | 2,5-dimethylpyrazine |
| Chemidplus: | 0000123320 |
| RTECS: | UQ2800000 for cas# 123-32-0 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| No odor group found for these |
| | sulfuryl octanoate | FL/FR |
|
| | butyl decanoate | FL/FR |
| | sulfuryl butyrate | FL/FR |
| | sulfuryl decanoate | FL/FR |
| | sulfuryl hexanoate | FL/FR |
| | sulfuryl isobutyrate | FL/FR |
| | sulfuryl propionate | FL/FR |
| aldehydic |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| balsamic |
| | guaiacyl phenyl acetate | FL/FR |
| | guaiyl acetate | FL/FR |
| bready |
| | coffee furanone | FL/FR |
| | furfural | FL/FR |
| | rum ether | FL/FR |
| caramellic |
| | ethyl cyclopentenolone | FL/FR |
| | fenugreek absolute | FL/FR |
| | maltol | FL/FR |
| iso | propenyl pyrazine | FL/FR |
| | shoyu furanone | FL/FR |
| | toffee furanone | FL/FR |
| | chocolate pyrazine A | FL/FR |
| | cocoa hexenal | FL/FR |
| 2,4,5- | trimethyl thiazole | FL/FR |
| cocoa |
| | theobroma cacao extract | FL/FR |
| earthy |
| 2- | ethyl-3-methoxypyrazine | FL/FR |
| | nutty pyrazine | FL/FR |
| (Z)- | oleic acid | FL/FR |
| fermented |
| iso | amyl alcohol | FL/FR |
| | methyl decanoate | FL/FR |
| floral |
| | champaca absolute | FR |
| | dimethyl benzyl carbinyl propionate | FR |
| | geranyl formate | FL/FR |
| alpha-iso | methyl ionone (90% min.) | FL/FR |
| | phenethyl isobutyrate | FL/FR |
| | tea acetate | FR |
| | tetrahydrolinalool | FL/FR |
| fruity |
| | heptyl butyrate | FL/FR |
| (E)-7- | methyl-3-octen-2-one | FL/FR |
| 1- | heptanol | FL/FR |
| 2- | heptyl furan | FL/FR |
| | magnolia flower oil | FL/FR |
| (E,Z)-2,6- | nonadien-1-ol | FL/FR |
| (E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| 2- | octen-1-ol | FL/FR |
| (E)-2- | octen-1-ol | FL/FR |
| herbal |
| 6- | acetoxydihydrotheaspirane | FL/FR |
| | clary sage absolute | FL/FR |
| | clary sage oil france | FL/FR |
| licorice |
| sweet | basil oleoresin | FL/FR |
| | sulfurol | FL/FR |
| | sulfuryl acetate | FL/FR |
| minty |
| dextro- | carvone | FL/FR |
| musty |
| 2- | acetyl pyrrole | FL/FR |
| 3- | acetyl-2,5-dimethyl furan | FL/FR |
| | cocoa butenal | FL/FR |
| | hazelnut pyrazine | FL/FR |
| | menthofuran | FL/FR |
| ketoiso | phorone | FL/FR |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2- | acetyl-3-methyl pyrazine | FL/FR |
| 2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| 5- | acetyl-4-methyl thiazole | |
| 2- | acetyl-5-methyl furan | FL/FR |
| roasted | chestnut fragrance | FR |
| 3,5- | cocoa pyrazine | FL/FR |
| 3,6- | cocoa pyrazine | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2,4- | dimethyl-5-ethyl thiazole | |
| 2- | ethyl pyrazine | FL/FR |
| | filbert heptenone | FL/FR |
| | filbert heptenone B | FL/FR |
| | filbert pyrazine | FL/FR |
| 2,6- | lutidine | FL/FR |
| | methoxymethyl pyrazine | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| 5- | methyl quinoxaline | FL/FR |
| | nutty quinoxaline | FL/FR |
| | sesame absolute | FL/FR |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| 2,4,5- | trimethyl oxazole | FL/FR |
| 2,3,5- | trimethyl pyrazine | FL/FR |
| | vinyl sulfurol | FL/FR |
| oily |
| | glyceryl tripropanoate | |
| popcorn |
| 2- | acetyl pyrazine | FL/FR |
| roasted |
| 2- | acetyl-2-pyrroline | |
| spicy |
| | caraway seed oleoresin | FL/FR |
| (-)- | cubenol | FL/FR |
| | furfuryl thioacetate | FL/FR |
| tropical |
| | genet absolute | FL/FR |
| | methional | FL/FR |
| 2- | methyl heptanoic acid | FL/FR |
| 2,4- | nonadien-1-ol | FL/FR |
| woody |
| | cyperus root oil (cyperus rotundus) | FR |
| (-)- | guaiol | FR |
| yeasty |
| laevo- | glutamic acid | CS |
| |
| For Flavor |
| |
| No flavor group found for these |
| 6- | acetoxydihydrotheaspirane | FL/FR |
| | acetyl acetaldehyde dimethyl acetal | FL |
| 2- | acetyl-2-pyrroline | |
| 5- | acetyl-4-methyl thiazole | |
| (E)- | aconitic acid | FL |
| | benzyl methyl sulfide | FL |
| | butyl decanoate | FL/FR |
| 2(4)-iso | butyl-4(2),6-dimethyl dihydro-4H-1,3,5-dithiazine | FL |
| | chocolate pyrazine A | FL/FR |
| | chocolate pyrazine B | FL |
| | cyclohexyl methyl pyrazine | FL |
| 2,5- | diethyl thiazole | FL |
| 6,7- | dihydro-2,3-dimethyl-5H-cyclopentapyrazine | FL |
| | dimethyl dihydrocyclopentapyrazine | FL |
| 6,7- | dimethyl dihydrocyclopentapyrazine | FL |
| 2,5- | dimethyl pyrazine and 2,6-dimethyl pyrazine mixture | FL |
| 2,5- | dimethyl thiazole | FL |
| 2,4- | dimethyl-5-ethyl thiazole | |
| | ethyl dimethyl pyrazine | FL |
| 2- | ethyl-3-methoxypyrazine | FL/FR |
| 2- | formyl pyrrole | FL |
| | green pea pyrazine | FL |
| | guaiyl acetate | FL/FR |
| | magnolia flower oil | FL/FR |
| 2- | methoxy-3-propyl pyrazine | FL |
| | methyl 2-(methyl thio) acetate | FL |
| 4-( | methyl thio) butanol | FL |
| | pyrazines mixture | FL |
| | sulfuryl butyrate | FL/FR |
| | sulfuryl decanoate | FL/FR |
| | sulfuryl hexanoate | FL/FR |
| | sulfuryl isobutyrate | FL/FR |
|
| 5- | acetyl-2,3-dihydro-1,4-thiazine | FL |
| 2,4- | dimethyl-3-oxazoline | FL |
| | sulfuryl formate | FL |
| | sulfuryl octanoate | FL/FR |
| | sulfuryl propionate | FL/FR |
| 1-(2- | thienyl) butanone | FL |
| alliaceous |
| 3- | mercapto-2-pentanone | FL |
| 2- | methyl thioacetaldehyde | FL |
| apple |
| (E,Z)-2,6- | nonadien-1-ol | FL/FR |
| bitter |
| | paullinia cupana seed extract | FL |
| bready |
| 2- | propionyl thiazole | FL |
| brown |
| | furfural | FL/FR |
| burnt |
| | furfuryl alcohol | FL |
| iso | propenyl pyrazine | FL/FR |
| | rum ether | FL/FR |
| 2,4,5- | trimethyl oxazole | FL/FR |
| caramellic |
| | fenugreek absolute | FL/FR |
| | maltol | FL/FR |
| | shoyu furanone | FL/FR |
| | toffee furanone | FL/FR |
| chemical |
| 2,5- | dimethyl furan | FL |
| citrus |
| ketoiso | phorone | FL/FR |
| cocoa |
| | butyraldehyde | FL |
| | cocoa hexenal | FL/FR |
| | theobroma cacao extract | FL/FR |
| coffee |
| | diisoamyl thiomalate | FL |
| 2,4- | dimethyl thiazole | FL |
| corn chip |
| 2- | acetyl-2-thiazoline | FL |
| fatty |
| 2,4- | decadienal | FL |
| | diacetyl trimer | FL |
| 2- | heptyl furan | FL/FR |
| | methyl decanoate | FL/FR |
| (E)-7- | methyl-3-octen-2-one | FL/FR |
| 2,4- | nonadien-1-ol | FL/FR |
| 2,4- | octadien-1-ol | FL |
| (E)-2- | octen-1-ol | FL/FR |
| 2- | octen-1-ol | FL/FR |
| (Z)- | oleic acid | FL/FR |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| fishy |
| 4,5- | dimethyl thiazole | FL |
| floral |
| alpha-iso | methyl ionone (90% min.) | FL/FR |
| | tetrahydrolinalool | FL/FR |
| 2- | ethyl-2,5-dihydro-4-methyl thiazole | FL |
| fusel |
| iso | amyl alcohol | FL/FR |
| green |
| | cocoa butenal | FL/FR |
| | dihydroxyacetophenone (mixed isomers) | FL |
| | geranyl formate | FL/FR |
| | heptyl butyrate | FL/FR |
| | methyl 2-undecynoate | FL |
| (E,Z)-2,6- | nonadien-1-yl acetate | FL/FR |
| | propylene glycol acetone ketal | FL |
| hay |
| | genet absolute | FL/FR |
| herbal |
| | clary sage absolute | FL/FR |
| | clary sage oil france | FL/FR |
| honey |
| | phenethyl isobutyrate | FL/FR |
| jammy |
| | ethyl cyclopentenolone | FL/FR |
| licorice |
| sweet | basil oleoresin | FL/FR |
| meaty |
| 3- | mercapto-2-butanone | FL |
| 2- | methyl 3-(methyl thio) furan | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| 2- | pyridinyl methane thiol | FL |
| | sulfurol | FL/FR |
| | sulfuryl acetate | FL/FR |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| milky |
| dextro,laevo-3-( | methyl thio) butanone | FL |
| minty |
| dextro- | carvone | FL/FR |
| musty |
| 2- | ethoxythiazole | FL |
| | hazelnut pyrazine | FL/FR |
| | menthofuran | FL/FR |
| | propionaldehyde | FL |
| 2,3,5- | trimethyl pyrazine | FL/FR |
| nutty |
| 2- | acetyl pyrrole | FL/FR |
| 3- | acetyl-2,5-dimethyl furan | FL/FR |
| 3- | acetyl-2,5-dimethyl thiophene | FL |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2- | acetyl-3-methyl pyrazine | FL/FR |
| 2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| 2- | acetyl-5-methyl furan | FL/FR |
| | arachis hypogaea fruit extract | FL |
| 3,5- | cocoa pyrazine | FL/FR |
| 3,6- | cocoa pyrazine | FL/FR |
| | coffee furanone | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2- | ethyl pyrazine | FL/FR |
| 1- | ethyl-2-acetyl pyrrole | FL |
| 2- | ethyl-6-methyl pyrazine | FL |
| | filbert heptenone | FL/FR |
| | filbert heptenone B | FL/FR |
| | filbert pyrazine | FL/FR |
| 2,6- | lutidine | FL/FR |
| | methoxymethyl pyrazine | FL/FR |
| 2- | methyl pyrazine | FL/FR |
| 5- | methyl quinoxaline | FL/FR |
| | nutty pyrazine | FL/FR |
| | nutty quinoxaline | FL/FR |
| | nutty thiazole | FL |
| | peanut oxazole | FL |
| | sesame absolute | FL/FR |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| 2,4,5- | trimethyl thiazole | FL/FR |
| | vinyl sulfurol | FL/FR |
| oily |
| | glyceryl tripropanoate | |
| phenolic |
| | guaiacyl phenyl acetate | FL/FR |
| popcorn |
| 2- | propionyl-2-thiazoline | FL |
| roasted |
| 2- | acetyl pyrazine | FL/FR |
| 3,5- | diisobutyl-1,2,4-trithiolane | FL |
| | furfuryl thioacetate | FL/FR |
| solvent |
| 1- | heptanol | FL/FR |
| spicy |
| | caraway seed oleoresin | FL/FR |
| (-)- | cubenol | FL/FR |
| sulfurous |
| | methyl 2-methyl-3-furyl disulfide | FL |
| 3- | methyl-2-butane thiol | FL |
| | potato butanone | FL |
| tomato |
| | methional | FL/FR |
| vegetable |
| | potato butyraldehyde | FL |
| waxy |
| | furfuryl octanoate | FL |
| 2- | methyl heptanoic acid | FL/FR |
| winey |
| 5- | ethyl-2-methyl pyridine | FL |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2,5- | dimethyl paradiazine | | 2,5- | dimethyl piazine | | 2,5- | dimethyl pyrazine natural | | 2,5- | dimethyl pyrazine, natural | | 2,5- | dimethyl-1,4-diazine | | 2,5- | dimethyl-pyrazine | | 2,5- | dimethylparadiazine | | 2,5- | dimethylpiazine | | 2, 5 | dimethylpyrazine | | 2,5- | dimethylpyrazine | | 2,5- | dimethylpyrazine >80.0%(gc) (contains 2,6-isomer) | | | ketine | | | pyrazine, 2,5- dimethyl | | | pyrazine, 2,5-dimethyl- |
Articles:
| PubMed: | Relationship of sensory and instrumental aroma measurements of dark chocolate as influenced by fermentation method, roasting and conching conditions. |
| J-Stage: | Chemical Profiles of Methylpyrazines Contained in Commercially Available Natto |
| PubMed: | HS-SPME GC/MS characterization of volatiles in raw and dry-roasted almonds (Prunus dulcis). |
| J-Stage: | Effect of 2,5-Dimethylpyrazine on Uterine Contraction in Late Stage of Pregnant Female Rats |
| PubMed: | Chemical communication during foraging in the harvesting ants Messor pergandei and Messor andrei. |
| J-Stage: | Effect of Alkylpyrazine Derivatives on the Duration of Pentobarbital-Induced Sleep, Picrotoxicin-Induced Convulsion and ?-Aminobutyric Acid (GABA) Levels in the Mouse Brain |
| PubMed: | Headspace-solid phase microextraction-gas chromatography-tandem mass spectrometry (HS-SPME-GC-MS2) method for the determination of pyrazines in perilla seed oils: impact of roasting on the pyrazines in perilla seed oils. |
| PubMed: | Stimulation of cell proliferation in the subventricular zone by synthetic murine pheromones. |
| PubMed: | Determination of the alkylpyrazine composition of coffee using stable isotope dilution-gas chromatography-mass spectrometry (SIDA-GC-MS). |
| PubMed: | Comparison of direct mass spectrometry methods for the on-line analysis of volatile compounds in foods. |
| PubMed: | Volatile profiling of high quality hazelnuts (Corylus avellana L.): chemical indices of roasting. |
| PubMed: | Characterization of cocoa liquors by GC-MS and LC-MS/MS: focus on alkylpyrazines and flavanols. |
| PubMed: | [Balance hypothesis of action of socially significant volatile chemosignals on reactivity of chromosome machinery of the bone marrow dividing cells in the house mouse Mus domesticus L]. |
| PubMed: | [Action of two pyrazine-containing chemosignals on cells of bone marrow and testes in male house mouse Mus musculus L]. |
| PubMed: | Volatile compounds of black cumin seeds (Nigella sativa L.) from microwave-heating and conventional roasting. |
| PubMed: | Identification of tartary buckwheat tea aroma compounds with gas chromatography-mass spectrometry. |
| PubMed: | GC-MS based metabolomics for rapid simultaneous detection of Escherichia coli O157:H7, Salmonella Typhimurium, Salmonella Muenchen, and Salmonella Hartford in ground beef and chicken. |
| PubMed: | [The role of metabolic activation of promutagens in the genome destabilization under pheromonal stress in the house mouse (Mus musculus)]. |
| PubMed: | Effects of roasting conditions on the physicochemical properties and volatile distribution in perilla oils (Perilla frutescens var. japonica). |
| PubMed: | Identification of 2-ethyl-4-methyl-3-thiazoline and 2-isopropyl-4-methyl-3-thiazoline for the first time in nature by the comprehensive analysis of sesame seed oil. |
| PubMed: | Grueneberg ganglion neurons are activated by a defined set of odorants. |
| PubMed: | Volatile composition and sensory analysis of Italian gianduja torrone. |
| PubMed: | High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones. |
| PubMed: | catena-Poly[[[diaqua-bis(8-hydroxy-quinoline N-oxide-κO)cobalt(II)]-μ-2,5-dimethyl-pyrazine 1,4-dioxide-κO:O] bis-(perchlorate)]. |
| PubMed: | [Effects of "pheromone-like" pyrazine-containing substances on stability of genetic apparatus in bone marrow cells of the male house mouse (Mus musculus L.)]. |
| PubMed: | Coffee aroma--statistical analysis of compositional data. |
| PubMed: | Syntheses, structures, and photoluminescence of a series of silver(I) sulfonates with pyrazine derivatives. |
| PubMed: | Alkyldimethylpyrazines in the defensive spray of Phyllium westwoodii: a first for order Phasmatodea. |
| PubMed: | Identification of chemicals emitted by calling males of the Sapote fruit fly, Anastrepha serpentina. |
| PubMed: | Strong through-space two-halide magnetic exchange of -234 K in (2,5-dimethylpyrazine)copper(II) bromide. |
| PubMed: | A binuclear Cu(II) metallacycle capable of discerning between pyrazine and its different methyl-substituted derivatives based on reversible intracage metal-ligand binding. |
| PubMed: | 2,5-Dimethyl-pyrazine 1,4-dioxide. |
| PubMed: | Formation of pyrazines and a novel pyrrole in Maillard model systems of 1,3-dihydroxyacetone and 2-oxopropanal. |
| PubMed: | [Effect of the estrous cycle stage on sensitivity to pheromone 2,5-dimethylpyrazine in the house mouse Mus musculus]. |
| PubMed: | Competition between photochemistry and energy transfer in UV-excited diazabenzenes. 4. UV photodissociation of 2,3-, 2,5-, and 2,6-dimethylpyrazine. |
| PubMed: | [Chromosomal abnormalities and spleenocyte production in laboratory mouse males after exposure to stress chemosignals]. |
| PubMed: | Structural study of silver(I) sulfonate complexes with pyrazine derivatives. |
| PubMed: | Mice respond differently to urine and its major volatile constituents from male and female ferrets. |
| PubMed: | Solitary foraging in the ancestral South American ant, Pogonomyrmex vermiculatus. Is it due to constraints in the production or perception of trail pheromones? |
| PubMed: | Construction of polyoxometalates-based coordination polymers through direct incorporation between polyoxometalates and the voids in a 2D network. |
| PubMed: | Degradation of 2,5-dimethylpyrazine by Rhodococcus erythropolis strain DP-45 isolated from a waste gas treatment plant of a fishmeal processing company. |
| PubMed: | Magnetic study on a two-dimensional coordination polymer with mixed bridging ligands. |
| PubMed: | Attenuation of the production of inositol 1,4,5-trisphosphate in the mouse vomeronasal organ by antibodies against the alphaq/11 subfamily of G-proteins. |
| PubMed: | Synthesis, a case of isostructural packing, and antimicrobial activity of silver(I)quinoxaline nitrate, silver(I)(2,5-dimethylpyrazine) nitrate and two related silver aminopyridine compounds. |
| PubMed: | [Induction of meiotic disturbances in spermatocytes I by pheromones as an inhibiting mechanism of male reproductive function in house mice]. |
| PubMed: | Influence of steric hindrance of organic ligand on the structure of Keggin-based coordination polymer. |
| PubMed: | Role of the solvent glycerol in the Maillard reaction of d-fructose and l-alanine. |
| PubMed: | Tuning the electronic communication and rates of intramolecular electron transfer of dimers of trinuclear ruthenium clusters: bridging and ancillary ligand effects. |
| PubMed: | Putative chemosignals of the ferret (Mustela furo) associated with individual and gender recognition. |
| PubMed: | Determination of the 2H/1H and 15N/14N ratios of Alkylpyrazines from coffee beans (Coffea arabica L. and Coffea canephoravar. robusta) by isotope ratio mass spectrometry. |
| PubMed: | Effects of water content on volatile generation and peptide degradation in the maillard reaction of glycine, diglycine, and triglycine. |
| PubMed: | Reactivity of epicatechin in aqueous glycine and glucose maillard reaction models: quenching of C2, C3, and C4 sugar fragments. |
| PubMed: | Identification of major histocompatibility complex-regulated body odorants by statistical analysis of a comparative gas chromatography/mass spectrometry experiment. |
| PubMed: | Synthesis, crystal structures, and magnetism of cobalt coordination polymers based on dicyanamide and pyrazine-dioxide derivatives. |
| PubMed: | Sex-specific responses to urinary chemicals by the mouse vomeronasal organ. |
| PubMed: | Aroma compounds in sweet whey powder. |
| PubMed: | Volatiles production and attractiveness to the Mexican fruit fly of Enterobacter agglomerans isolated from apple maggot and Mexican fruit flies. |
| PubMed: | Primer effects by conspecific odors in house mice: a new perspective in the study of primer effects on reproductive activities. |
| PubMed: | Pyrazine derivatives in cigarette smoke inhibit hamster oviductal functioning. |
| PubMed: | Odors detected by mice deficient in cyclic nucleotide-gated channel subunit A2 stimulate the main olfactory system. |
| PubMed: | [Chemical profiles of methylpyrazines contained in commercially available natto]. |
| PubMed: | [Induction of dominant lethals in progeny of male CBA mice after pheromonal action]. |
| PubMed: | Effect of 2,5-dimethylpyrazine on uterine contraction in late stage of pregnant female rats. |
| PubMed: | [The female pheromone 2,5-dimethylpyrazine induces sperm head abnormalities in male CBA mice]. |
| PubMed: | Purine metabolizing capability of Enterobacter agglomerans affects volatiles production and attractiveness to Mexican fruit fly. |
| PubMed: | [Olfactory stress and modification of phagocytosis in peripheral blood cells of adult male mice]. |
| PubMed: | catena-poly[[(acetonitrile-N)dichlorocopper(II)]-mu-2,5-dimethylpyrazine-kappa2N:N']. |
| PubMed: | Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain. |
| PubMed: | 1-octen-3-ol isolated from bont ticks attracts Amblyomma variegatum. |
| PubMed: | Syntheses, structures, and physicochemical properties of diruthenium compounds of tetrachlorocatecholate with metal-metal bonded Ru(3+)(mu-OR)(2)Ru(3+) and Ru(3.5+)(mu-OR)(2)Ru(3.5+) cores (R = CH(3) and C(2)H(5)). |
| PubMed: | Recruitment pheromone in the harvester ant genus Pogonomyrmex. |
| PubMed: | [Genotype-specific changes of certain functional indicators of immunocompetent cells in male laboratory mice under conditions of pheromone stress]. |
| PubMed: | Volatile flavor components of rice cakes. |
| PubMed: | Pyrazine formation from serine and threonine. |
| PubMed: | Effects of roasting on pyrazine contents and oxidative stability of red pepper seed oil prior to its extraction. |
| PubMed: | Oxidative DNA damage induced by aminoacetone, an amino acid metabolite. |
| PubMed: | Role of the adrenal gland and adrenal-mediated chemosignals in suppression of estrus in the house mouse: the lee-boot effect revisited. |
| PubMed: | Inhibitory effect of 2,5-dimethylpyrazine on oxytocic agent-induced uterine hypercontraction of normal or pregnant female rats. |
| PubMed: | [Physiological and pharmacological activities of simple alkyl- and arylpyrazines]. |
| PubMed: | Rational Design of a Novel Intercalation System. Layer-Gap Control of Crystalline Coordination Polymers, {[Cu(CA)(H(2)O)(m)()](G)}(n)() (m = 2, G = 2,5-Dimethylpyrazine and Phenazine; m = 1, G = 1,2,3,4,6,7,8,9-Octahydrophenazine). |
| PubMed: | Attractants fromStaphylococcus aureus cultures for Mexican fruit fly,Anastrepha ludens. |
| PubMed: | Effects of 2,5-dimethylpyrazine on plasma testosterone and polyamines- and acid phosphatase-levels in the rat prostate. |
| PubMed: | Inhibition of sexual maturation in juvenile female and male mice by a chemosignal of female origin. |
| PubMed: | Long-term effect of a urinary chemosignal on reproductive fitness in female mice. |
| PubMed: | Effects of dimethylpyrazine isomers on reproductive and accessory reproductive organs in male rats. |
| PubMed: | Contents of poison apparatus and their relation to trail-following in the antDaceton armigerum. |
| PubMed: | Effects of 2,5-dimethylpyrazine on reproductive and accessory reproductive organs in female rats. |
| PubMed: | Chemotaxonomic study of undescribed species ofMyrmica ant from Idaho. |
| PubMed: | Interactions of heterocyclic Maillard products with the hepatic microsomal monooxygenase system. |
| PubMed: | Dynamics of excretion of urinary chemosignals in the house mouse (Mus musculus) during the natural estrous cycle. |
| PubMed: | Adrenal-mediated endogenous metabolites inhibit puberty in female mice. |
| PubMed: | Synthesis and antimetastatic properties of stereoisomeric tricyclic bis(dioxopiperazines) in the Lewis lung carcinoma model. |
| PubMed: | Identification of trail pheromone of the antTetramorium caespitum L. (Hymenoptera: Myrmicinae). |
| PubMed: | Identification of 2,5-dimethyl-pyrazine in the volatile flavour compounds of potato chips. |
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