|
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 175.00 to 176.00 °C. @ 760.00 mm Hg (est)
|
| Vapor Pressure: | 1.573000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 146.00 °F. TCC ( 63.60 °C. ) (est)
|
| logP (o/w): | 0.555 (est) |
| Soluble in: |
| | alcohol | | | water, 4063 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: sulfurous |
| |
| Odor Strength: | high , recommend smelling in a 0.10 % solution or less |
| |
| | sweet sulfurous onion onion cooked onion |
Odor Description: at 0.10 % in dipropylene glycol. | sweet sulfurous onion |
| |
| |
| Flavor Type: sulfurous |
| |
| | sweet sulfurous ripe onion |
Taste Description:
| sweet sulfurous ripe onion |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 900 mg/kg European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 235, 1982.
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | information only not used for fragrances or flavors |
| Recommendation for 1,3-dithiolane usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for 1,3-dithiolane flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| alliaceous |
| | dibutyl sulfide | FL/FR |
| | dimethyl trisulfide | FL/FR |
| | dipropyl disulfide | FL/FR |
| | ferula assa-foetida gum oil | FL/FR |
| | methyl furfuryl disulfide | FL/FR |
| | propyl mercaptan | FL/FR |
| S-( | methyl thio) butyrate | FL/FR |
| citrus |
| | grapefruit mercaptan | FL/FR |
| coffee |
| | coffee difuran | FL/FR |
| | furfuryl mercaptan | FL/FR |
| ethereal |
| 2- | methyl-1-butanol | FL/FR |
| fermented |
| | ethyl (E)-2-crotonate | FL/FR |
| | tropical thiazole | FL/FR |
| | tropical trithiane | FL/FR |
| iso | propyl thioisovalerate | FL/FR |
| | thiogeraniol | FL/FR |
| meaty |
| | meaty dithiane | FL/FR |
| nutty |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| sulfurous |
| 2- | acetyl thiophene | FL/FR |
| | benzothiazole | FL/FR |
| | blackberry thiophenone | FL/FR |
| | buchu mercaptan | FL/FR |
| | cassis pentanone | FL/FR |
| | cocoa essence | FL/FR |
| | dimethyl disulfide | FL/FR |
| | dimethyl sulfide | FL/FR |
| | ethyl 2-mercaptopropionate | FL/FR |
| | ethyl methyl mercaptopropionate | FL/FR |
| | ferula assa-foetida absolute | FL/FR |
| | fish thiol | FL/FR |
| | furfuryl thioacetate | FL/FR |
| S- | furfuryl thioformate | FL/FR |
| | grapefruit menthane | FL/FR |
| | lychee mercaptan acetate | FL/FR |
| | mango thiol | FL/FR |
| 2- | mercaptopropionic acid | FL/FR |
| 4- | methoxy-2-methyl butane thiol | FL/FR |
| (S)-1- | methoxy-3-heptane thiol | FL/FR |
| | methyl 3-(methyl thio) propionate | FL/FR |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| | methyl mercaptan | FL/FR |
| 3-( | methyl thio) hexanol | FL/FR |
| 2-( | methyl thio) phenol | FL/FR |
| | onion oil | FL/FR |
| | onion oil dutch | FL/FR |
| | onion oil egypt | FL/FR |
| | onion oil mexico | FL/FR |
| | passiflora acetate | FL/FR |
| 1- | phenethyl mercaptan | FL/FR |
| 3- | thiohexanol | FL/FR |
| S- | tropical 2-thiobutyrate | FL/FR |
| tropical |
| cis- | galbanum oxathiane | FL/FR |
| vegetable |
| 1- | furfuryl pyrrole | FL/FR |
| | methional | FL/FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | allyl methyl disulfide | FL |
| | allyl methyl trisulfide | FL |
| | allyl propyl disulfide | FL |
| | allyl propyl sulfide | FL |
| | allyl propyl trisulfide | FL |
| sec- | amyl mercaptan | FL |
| | amyl mercaptan | FL |
| iso | amyl mercaptan | FL |
| | amyl methyl disulfide | FL |
| | blackberry thiophenone | FL/FR |
| 1,2- | butane dithiol | FL |
| | butyl disulfide | FL |
| | butyl ethyl disulfide | FL |
| sec- | butyl isothiocyanate | FL |
| | butyl isothiocyanate | FL |
| tert- | butyl mercaptan | FL |
| iso | butyraldehyde sulfided | FL |
| | diethyl sulfide | FL |
| | diethyl trisulfide | FL |
| | diisopropyl sulfide | FL |
| | diisopropyl trisulfide | FL |
| (Z+E)-2,5- | dimethyl-3-tetrahydrofuran thiol | FL |
| (Z+E)-2,5- | dimethyl-3-thioacetoxytetrahydrofuran | FL |
| | dipropyl sulfide | FL |
| 2,5- | dithiahexane | FL |
| | ethyl 2-(methyl dithio) propionate | FL |
| | ethyl 2-(methyl thio) acetate | FL |
| | ethyl 4-(acetyl thio) butyrate | FL |
| | ethyl 4-(methyl thio) butyrate | FL |
| | ethyl 5-(methyl thio) valerate | FL |
| | ethyl mercaptan | FL |
| | ethyl methyl trisulfide | FL |
| | ethyl propyl disulfide | FL |
| | ethyl propyl trisulfide | FL |
| | ethylene mercaptan | FL |
| | furfuryl propyl disulfide | FL |
| 2- | heptane thiol | FL |
| | heptyl mercaptan | FL |
| | hexanal sulfided | FL |
| 2- | hexyl thiophene | FL |
| 4- | mercapto-2-butanone | FL |
| 2- | mercapto-2-methyl-1-pentanol | FL |
| 3- | mercaptopropionic acid | FL |
| bis(1- | mercaptopropyl) sulfide | FL |
| 4- | methyl 4-mercaptopentan-2-one 1% solution | FL/FR |
| S- | methyl benzothioate | FL |
| | methyl butyl sulfide | FL |
| | methyl methane thiosulfonate | FL |
| 4-( | methyl thio) butanol | FL |
| 2-( | methyl thio) ethanol | FL |
| 2-( | methyl thio) methyl-2-butenal | FL |
| 1-( | methyl thio)-1-butene | FL |
| | methyl thiomethyl mercaptan | FL |
| S- | methyl thiopropionate | FL |
| 2- | methyl-1-butane thiol | FL |
| | methyl-1-propenyl trisulfide | FL |
| 3- | methyl-1,2,4-trithiolane | FL |
| 2- | methyl-2-thiazoline | FL |
| 2- | methyl-3-furyl tetrasulfide | FL |
| 2- | methyl-3-thioacetoxy-4,5-dihydrofuran | FL |
| 2- | methyl-5-methoxythiazole | FL |
| 1,9- | nonane dithiol | FL |
| 1- | phenethyl mercaptan | FL/FR |
| | prenyl mercaptan | FL |
| 1,1- | propane dithiol | FL |
| 1,3- | propane dithiol | FL |
| | propenyl propyl disulfide | FL |
| | propionaldehyde sulfided | FL |
| iso | propyl disulfide | FL |
| iso | propyl thioisovalerate | FL/FR |
| | pyrazinyl methyl sulfide | FL |
| 1-(2'- | thienyl) ethyl mercaptan | FL |
| | thioterpenes | FL |
| 2,4,6- | trimethyl-1,3,5-trithiane | FL |
| 2,3,5- | trithiahexane | FL |
| S- | tropical 2-thiobutyrate | FL/FR |
| iso | valeraldehyde sulfided | FL |
|
| | allyl thiohexanoate | FL |
| (±)-3,5- | diethyl-1,2,4-trithiolane | FL |
| 3,5- | dimethyl-1,2,4-trithiolane | FL |
| 3- | mercapto-3-methyl-1-butyl acetate | FL |
| alliaceous |
| | allium porrum extract | FL |
| | allyl disulfide | FL |
| | allyl mercaptan | FL |
| | allyl thiopropionate | FL |
| | benzyl mercaptan | FL |
| 1,3- | butane dithiol | FL |
| | cyclopentyl mercaptan | FL |
| | dicyclohexyl disulfide | FL |
| | diethyl disulfide | FL |
| | dimethyl trisulfide | FL/FR |
| | dipropyl disulfide | FL/FR |
| | dipropyl trisulfide | FL |
| | ferula assa-foetida gum oil | FL/FR |
| | leek oil | FL |
| 3- | mercapto-2-methyl pentanol | FL |
| 3- | mercapto-2-pentanone | FL |
| | methyl 3-mercaptobutanoate | FL |
| 2- | methyl thioacetaldehyde | FL |
| | onion oil extenders | FL |
| | propyl mercaptan | FL/FR |
| 3- | tetrahydrothiophenone | FL |
| | tropical thiazole | FL/FR |
| | truffle sulfide | FL |
| berry |
| (S)-1- | methoxy-3-heptane thiol | FL/FR |
| burnt |
| | furfuryl alcohol | FL |
| cabbage |
| | methyl 2-thiofuroate | FL |
| cherry |
| | thenaldehyde | FL |
| chocolate |
| | cocoa essence | FL/FR |
| citrus |
| | grapefruit mercaptan | FL/FR |
| 3- | mercaptoheptyl acetate | FL |
| cocoa |
| | cocoa distillates | FL |
| coffee |
| | coffee difuran | FL/FR |
| | furfuryl mercaptan | FL/FR |
| | methyl furfuryl disulfide | FL/FR |
| | methyl furfuryl thiol | FL |
| corn chip |
| 2- | acetyl-2-thiazoline | FL |
| earthy |
| | difurfuryl sulfide | FL |
| 1,8- | octane dithiol | FL |
| eggy |
| iso | propyl mercaptan | FL |
| ethereal |
| 2- | methyl-1-butanol | FL/FR |
| fermented |
| | methyl thio isovalerate | FL |
| fruity |
| 3- | mercaptohexyl hexanoate | FL |
| | methionyl butyrate | FL |
| | passion fruit distillates | FL |
| | tropical trithiane | FL/FR |
| garlic |
| | allyl methyl sulfide | FL |
| | garlic oleoresin | FL |
| green |
| | cassis pentanone | FL/FR |
| | dibutyl sulfide | FL/FR |
| 2,5- | dimethyl thiophene | FL |
| cis- | galbanum oxathiane | FL/FR |
| | horseradish oil | FL |
| 4- | penten-1-yl acetate | FL |
| | thiogeraniol | FL/FR |
| herbal |
| | buchu oil fractions | FL |
| juicy |
| | lychee mercaptan acetate | FL/FR |
| malty |
| | yeast thiazoline | FL |
| meaty |
| | benzothiazole | FL/FR |
| 2,6- | dimethyl thiophenol | FL |
| 2,5- | dimethyl-3-furan thiol | FL |
| | furfuryl 2-methyl-3-furyl disulfide | FL |
| | meaty dithiane | FL/FR |
| 3- | mercapto-2-butanone | FL |
| (R,S)-2- | mercapto-3-butanol | FL |
| 2- | mercaptopropionic acid | FL/FR |
| 2-( | methyl thio) phenol | FL/FR |
| bis(2- | methyl-3-furyl) disulfide | FL |
| S-(2- | methyl-3-furyl) ethane thioate | FL |
| 2- | methyl-3-tetrahydrofuran thiol | FL |
| | phenyl mercaptan | FL |
| | pyrazinyl ethane thiol | FL |
| 2- | pyridinyl methane thiol | FL |
| ortho- | thiocresol | FL |
| ortho- | thioguaiacol | FL |
| metallic |
| 2,5- | dihydroxy-1,4-dithiane | FL |
| 3-( | methyl thio) hexanol | FL/FR |
| milky |
| dextro,laevo-3-( | methyl thio) butanone | FL |
| mustard |
| | allyl isothiocyanate | FL |
| musty |
| | ethyl (E)-2-crotonate | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| S-( | methyl thio) butyrate | FL/FR |
| nutty |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| | nutty thiazole | FL |
| onion |
| 2- | acetyl thiophene | FL/FR |
| | ethyl 2-mercaptopropionate | FL/FR |
| | methionol | FL |
| | methyl propyl disulfide | FL |
| | methyl propyl trisulfide | FL |
| 2- | methyl-1,3-dithiolane | FL |
| | propyl thioacetate | FL |
| phenolic |
| 2- | ethyl benzene thiol | FL |
| roasted |
| | ethyl 3-(furfuryl thio) propionate | FL |
| | furfuryl thioacetate | FL/FR |
| | hexyl mercaptan | FL |
| | methyl isopentyl disulfide | FL |
| savory |
| 2,4,6- | triethyl tetrahydro-1,3,5-dithiazine | FL |
| seafood |
| 1,4- | dithiane | FL |
| sulfurous |
| | allium sativum bulb extract | FL |
| | allyl sulfide | FL |
| | buchu mercaptan | FL/FR |
| 2,3- | butane dithiol | FL |
| | butyl mercaptan | FL |
| | diallyl polysulfides | FL |
| | diallyl tetrasulfide | FL |
| | diallyl trisulfide | FL |
| | dimethyl disulfide | FL/FR |
| | dimethyl sulfide | FL/FR |
| | diphenyl disulfide | FL |
| | ethyl methyl mercaptopropionate | FL/FR |
| | ethyl methyl sulfide | FL |
| S- | ethyl thioacetate | FL |
| | ferula assa-foetida absolute | FL/FR |
| | fish thiol | FL/FR |
| | furfuryl methyl sulfide | FL |
| S- | furfuryl thioformate | FL/FR |
| | furfuryl thiopropionate | FL |
| | grapefruit menthane | FL/FR |
| | mango thiol | FL/FR |
| 3- | mercapto-2-methyl pentanal | FL |
| 3- | mercapto-2-methyl-1-butanol | FL |
| 4- | methoxy-2-methyl butane thiol | FL/FR |
| | methyl 2-(methyl thio) butyrate | FL |
| | methyl 2-methyl-3-furyl disulfide | FL |
| | methyl 4-(methyl thio) butyrate | FL |
| | methyl benzyl disulfide | FL |
| | methyl ethyl disulfide | FL |
| | methyl mercaptan | FL/FR |
| 1-( | methyl thio)-2-butanone | FL |
| | methyl thioacetate | FL |
| | methyl thiomethyl butyrate | FL |
| 2- | methyl thiophene | FL |
| 2- | naphthyl mercaptan | FL |
| | onion oil | FL/FR |
| | onion oil dutch | FL/FR |
| | onion oil egypt | FL/FR |
| | onion oil mexico | FL/FR |
| | onion oleoresin | FL |
| | potato butanone | FL |
| | roasted butanol | FL |
| 3- | thiohexanol | FL/FR |
| tomato |
| | methional | FL/FR |
| tropical |
| 3- | mercaptohexyl butyrate | FL |
| | passiflora acetate | FL/FR |
| vegetable |
| alpha- | benzylidene methional | FL |
| 1- | furfuryl pyrrole | FL/FR |
| | methyl 3-(methyl thio) propionate | FL/FR |
| | potato butyraldehyde | FL |
| | radish isothiocyanate | FL |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
Articles:
| PubMed: | Design, synthesis, and antimelanogenic effects of (2-substituted phenyl-1,3-dithiolan-4-yl)methanol derivatives. |
| PubMed: | Indium-Catalyzed Reductive Dithioacetalization of Carboxylic Acids with Dithiols: Scope, Limitations, and Application to Oxidative Desulfurization. |
| PubMed: | Development and comparison of HPLC and MEKC methods for the analysis of cyclic sulfur mustard degradation products. |
| PubMed: | Synthesis of ferrocenyl-substituted 1,3-dithiolanes via [3 + 2]-cycloadditions of ferrocenyl hetaryl thioketones with thiocarbonyl S-methanides. |
| PubMed: | Diradical reaction mechanisms in [3 + 2]-cycloadditions of hetaryl thioketones with alkyl- or trimethylsilyl-substituted diazomethanes. |
| PubMed: | Development of a dynamic headspace gas chromatography-mass spectrometry method for on-site analysis of sulfur mustard degradation products in sediments. |
| PubMed: | Selective arylthiolane deprotection by singlet oxygen: a promising tool for sensors and prodrugs. |
| PubMed: | Cross-dehydrogenative coupling of azoles with α-C(sp3)-H of ethers and thioethers under metal-free conditions: functionalization of H-N azoles via C-H activation. |
| PubMed: | Synthesis of pyrrolidine-fused 1,3-dithiolane oligomers by the cycloaddition of polycyclic dithiolethiones to maleimides and evaluation as mercury(II) indicators. |
| PubMed: | Molecular mechanisms of (R,R)ZX-5 on NO synthesis and its anti-angiogenic effect. |
| PubMed: | 1-Oxo-1,3-dithiolanes--synthesis and stereochemistry. |
| PubMed: | Cationic cyclization of 2-alkenyl-1,3-dithiolanes: diastereoselective synthesis of trans-decalins. |
| PubMed: | Structural requirements of (E)-6-benzylidene-4a-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one derivatives as novel melanogenesis inhibitors. |
| PubMed: | Lead detoxification activities and ADMET hepatotoxicities of a class of novel 5-(1-carbonyl-L-amino-acid)-2,2-dimethyl-[1,3]dithiolane-4-carboxylic acids. |
| PubMed: | The mechanism of (R,R) ZX-5 on increasing NO release. |
| PubMed: | A bimetallic aluminum(salen) complex for the synthesis of 1,3-oxathiolane-2-thiones and 1,3-dithiolane-2-thiones. |
| PubMed: | Diastereoselective formal total synthesis of (+/-)-triptolide via a novel cationic cyclization of 2-alkenyl-1,3-dithiolane. |
| PubMed: | Novel Cr(III) dinuclear complexes supported by salicyloylhydrazono dithiolane and dithiane ligands: synthesis, stability, crystal structures and magnetic properties. |
| PubMed: | Headspace-trap gas chromatography-mass spectrometry for determination of sulphur mustard and related compounds in soil. |
| PubMed: | Trace determination of sulphur mustard and related compounds in water by headspace-trap gas chromatography-mass spectrometry. |
| PubMed: | Synthesis, DNA intercalation and 3D QSAR analysis of cis-2,4,5-trisubstituted-1,3-dithiolanes as a novel class of antitumor agents. |
| PubMed: | 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors. |
| PubMed: | Synthesis and magnetic properties of new mono- and binuclear iron complexes with salicyloylhydrazono dithiolane ligand. |
| PubMed: | Comparative molecular dynamics simulations of the potent synthetic classical cannabinoid ligand AMG3 in solution and at binding site of the CB1 and CB2 receptors. |
| PubMed: | Nucleophilic additions to alkylidene bis(sulfoxides): stereoelectronic effects in vinyl sulfoxides. |
| PubMed: | Efficient cleavage of the N-O bond of 3,6-dihydro-1,2-oxazines mediated by some alpha-hetero substituted carbonyl compounds in mild conditions. |
| PubMed: | Dinuclear Cp* cobalt complexes of the 1,2,4,5-benzenetetrathiolate bischelating ligand. |
| PubMed: | Combined 3D QSAR and molecular docking studies to reveal novel cannabinoid ligands with optimum binding activity. |
| PubMed: | Stereoelectronic effects in cyclic sulfoxides, sulfones, and sulfilimines: application of the Perlin effect to conformational analysis. |
| PubMed: | Intramolecular thia-anti-Michael addition of a sulfur anion to enones: a regiospecific approach to multisubstituted thiophene derivatives. |
| PubMed: | General strategy for the syntheses of corynanthe, tacaman, and oxindole alkaloids. |
| PubMed: | Reaction of the acetals with TESOTf-base combination; speculation of the intermediates and efficient mixed acetal formation. |
| PubMed: | Very strong ferromagnetic interaction in a new binuclear mu-methoxo-bridged Mn(III) complex: synthesis, crystal structure, magnetic properties, and DFT calculations. |
| PubMed: | Heteroatom-substituted expanded radialenes: one-pot synthesis and characterization of expanded 1,3-dithiolane[n]radialenes. |
| PubMed: | gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride. |
| PubMed: | Alpha-keto amide peptides: a synthetic strategy to resin-bound peptide isosteres for protease inhibitor screening on solid support. |
| PubMed: | A computational study of the cycloaddition of thiobenzophenone S-methylide to thiobenzophenone. |
| PubMed: | A new approach to the chemical synthesis of keto-proteins. |
| PubMed: | Highly diastereoselective 1,3-dipolar cycloaddition reactions of trans-2-methylene-1,3-dithiolane 1,3-dioxide with 3-oxidopyridinium and 3-oxidopyrylium betaines: a route to the tropane skeleton. |
| PubMed: | Relationship between nitric oxide production and choroidal blood flow. |
| PubMed: | Thioformaldehyde S-methylide and thioacetone S-methylide: an ab initio MO study of structure and cycloaddition reactivity. |
| PubMed: | Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells. |
| PubMed: | Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid. |
| PubMed: | C-H activation with elemental sulfur: synthesis of cyclic thioureas from formaldehyde aminals and S8. |
| PubMed: | Dynamic NMR studies of a potential chiroptical switch based on dithiocarbamate-iminodithiolane interconversion. |
| PubMed: | Dithiolane analogs of lignans inhibit interferon-gamma and lipopolysaccharide-induced nitric oxide production in macrophages. |
| PubMed: | Differential membrane fluidization by active and inactive cannabinoid analogues. |
| PubMed: | Palladium-catalyzed cyclization reactions of 2-vinylthiiranes with heterocumulenes. Regioselective and enantioselective formation of thiazolidine, oxathiolane, and dithiolane derivatives. |
| PubMed: | Eicosanoid regulation of angiogenesis: role of endothelial arachidonate 12-lipoxygenase. |
| PubMed: | Synthesis of 1,3-dithianes and 1,3-dithiolanes. Baker's yeast reduction and lipase-catalyzed resolution for synthesis of enantiopure derivatives. |
| PubMed: | Structure elucidation and conformational properties of synthetic cannabinoids (-)-2-(6a,7,10,10a-tetrahydro-6,6,9-trimethyl-1-hydroxy-6H-dibe nzo [b,d]pyranyl)-2-hexyl-1,3-dithiolane and its methylated analog. |
| PubMed: | Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols. |
| PubMed: | Apoptosis in the absence of cytochrome c accumulation in the cytosol. |
| PubMed: | Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity. |
| PubMed: | Requirement for epidermal growth factor receptor tyrosine kinase and for 12-lipoxygenase activity in the expression of 12-lipoxygenase in human epidermoid carcinoma cells. |
| PubMed: | Critical role of arachidonate lipoxygenases in regulating apoptosis. |
| PubMed: | EGF-receptor tyrosine kinase and 12-lipoxygenase activity regulate expression of 12-lipoxygenase in human tumor cells. |
| PubMed: | Hepatotoxicity of diisopropyl ester of malonic acid and chloromalonic acids, disinfection by-products of the fungicide isoprothiolane. |
| PubMed: | Meso-2,3-dimercaptosuccinic acid mono-N-alkylamides: syntheses and biological activity as novel in vivo cadmium mobilizing agents. |
| PubMed: | Synthesis of [4,5-Bis(hydroxymethyl)-1,3-dithiolan-2-yl]nucleosides as Potential Inhibitors of HIV(1). |
| PubMed: | Plasmalogens and their oxidative degradation products in low and high density lipoprotein. |
| PubMed: | 12(S)-HETE is a mitogenic factor for microvascular endothelial cells: its potential role in angiogenesis. |
| PubMed: | Enhanced endothelial cell retraction mediated by 12(S)-HETE: a proposed mechanism for the role of platelets in tumor cell metastasis. |
| PubMed: | Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols. |
| PubMed: | [Studies on metabolism of fungicide benzoic acid, 1,3-dithiolan-2-ylidenehydrazide in vitro]. |
| PubMed: | [Studies on metabolism of a fungicide yekuling in rat]. |
| PubMed: | Metabolism of 7-(1,3-dithiolan-2-ylmethyl)-1,3-dimethylxanthine by rat liver microsomes. Diastereoselective metabolism of the 1,3-dithiolane ring. |
| PubMed: | Stereoselective S-oxygenation of 2-aryl-1,3-dithiolanes by the flavin-containing and cytochrome P-450 monooxygenases. |
| PubMed: | Enantioselective S-oxygenation of 2-aryl-1,3-dithiolanes by rabbit lung enzyme preparations. |
| PubMed: | Enantioselective S-oxygenation of para-methoxyphenyl-1,3-dithiolane by various tissue preparations: effect of estradiol. |
| PubMed: | 2,3-Dithioerythritol, a possible new arsenic antidote. |
| PubMed: | Immunohistochemical study of arachidonate 12-lipoxygenase in porcine tissues. |
| PubMed: | [In vitro transformation of Syrian hamster embryo cells by four chemicals]. |
| PubMed: | [Studies on toxicokinetics of 14C-Yekuling in rats after intratracheal injection]. |
| PubMed: | Potential anticonvulsants. 11. Synthesis and anticonvulsant activity of spiro[1,3-dioxolane-2,3'-indolin]-2'-ones and structural analogues. |
| PubMed: | [An experimental study on the embryotoxicity and teratogenicity of a new fungicide "Yu-7802" (BHD) in mice]. |
| PubMed: | [Studies on the carcinogenicity of a new fungicide, 2-benzoyl-hydrazono-1,3-dithiolane (BHD), in rats]. |
| PubMed: | Potent cephalosporinase inhibitors: 7 beta-[2-(1, 3-dithiolan-2-ylidene) acetamido] cephalosporins and related compounds. |
| PubMed: | Occupational effect of phosfolan insecticide on spraymen during field exposure. |
| PubMed: | [Cyclic ketals. 10. Oxidation behavior of 2-substituted 1,3-dithiolane and 1,3-dithane]. |
| PubMed: | [Thermal decomposition of cysteine, cystine, N-acetylcysteine, 4-thiazolidinecarboxylic acid and cysteine methyl ester in soy bean oil (authors transl)]. |
| PubMed: | [Hydrolytic stability of various 1,3-dioxolane, 1,3-oxathiolane and 1,3-dithiolane derivatives]. |
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