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Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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| Odor Type: sulfurous |
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| | sulfurous coffee nutty |
Odor Description: at 0.10 % in dipropylene glycol. | sulfurous coffee nutty |
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| Flavor Type: sulfurous |
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| | coffee |
Taste Description:
| coffee |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for S-furfuryl thioformate usage levels up to: | | | 0.0200 % in the fragrance concentrate.
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| Maximised Survey-derived Daily Intakes (MSDI-EU): | 1.30 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.02 (μg/capita/day) |
| NOEL (No Observed Effect Level): | 0.83 (mg/kg bw per day) |
| Structure Class: | III |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 4 |
| Click here to view publication 4 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | - |
| beverages(nonalcoholic): | - | 1.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 1.00000 |
| fruit ices: | - | 1.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 1.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 View page or View pdf |
Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of “Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14” evaluated by EFSA in FGE.13Rev1 (2009) View page or View pdf |
Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 65, Revision 1 (FGE.65Rev1): Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of ‘Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14’ evaluated by EFSA in FGE.13Rev2 (2011) View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 59020-90-5 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 62144 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | S-(furan-2-ylmethyl) methanethioate |
| Chemidplus: | 0059020905 |
References:
Other Information:
Potential Blenders and core components note
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| For Odor |
| No odor group found for these |
| | chicory root | |
| 3,6- | dimethyl pyrazine-2-thiol | |
| 2,5- | dimethyl-3-furfurylthio-pyrazine | |
| 2,5- | dimethyl-3,6-diethyl pyrazine | |
| 2,6- | dimethyl-gamma-thiopyrone | |
| 2,6- | dimethyl-thio-gamma-pyrone | |
| 2- | hydroxymethyl-6-methyl-pyridine | |
| 4- | hydroxymethyl-pyridine | |
| 2- | methyl-3-pentyl pyrazine | |
| 2- | pentenyl furan | |
| 2-(1- | propenyl) pyridine | |
| 2-( | thienyl-2)-ethanethiol | |
| 2,3,5- | trimethyl phenol | FR |
| | methyl furfuryl disulfide | FL/FR |
| balsamic |
| 2- | acetyl furan | FL/FR |
| burnt |
| 2- | ethyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| | coffee dione | FL/FR |
| | cyclotene | FL/FR |
| | fenugreek absolute | FL/FR |
| | fenugreek oleoresin | FL/FR |
| iso | propenyl pyrazine | FL/FR |
| chocolate |
| | cocoa hexenal | FL/FR |
| 2,6- | dimethyl pyrazine | FL/FR |
| 2,4,5- | trimethyl thiazole | FL/FR |
| cocoa |
| 2- | methyl butyraldehyde | FL/FR |
| coffee |
| | cichorium intybus root extract | FL/FR |
| | cichorium intybus root solid extract | FL/FR |
| | coffea arabica seed extract | FL/FR |
| roasted | coffea arabica seed extract | FL/FR |
| | coffea arabica seed oil | FL/FR |
| | coffee absolute | FL/FR |
| arabica | coffee bean butter | FL/FR |
| roasted arabica | coffee bean essence | FL/FR |
| roasted | coffee bean extract | FL/FR |
| roasted arabica | coffee bean oil | FL/FR |
| roasted arabica | coffee bean oil CO2 extract | FL/FR |
| | coffee bean oil extract | FL/FR |
| | coffee difuran | FL/FR |
| | coffee resinoid | FL/FR |
| | furfuryl mercaptan | FL/FR |
| 1- | hydroxy-2-butanone | FL/FR |
| 2- | methyl-3-,5 or 6-(furfuryl thio) pyrazine | FL/FR |
| | nutty pyrazine | FL/FR |
| | tropical thiazole | FL/FR |
| herbal |
| | thymyl methyl ether | FL/FR |
| medicinal |
| 2,6- | xylenol | FL/FR |
| | menthofuran | FL/FR |
| nutty |
| 3,5- | cocoa pyrazine | FL/FR |
| 2,3- | dimethyl pyrazine | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| 2- | ethyl-4-methyl thiazole | FL/FR |
| | filbert heptenone | FL/FR |
| 2,6- | lutidine | FL/FR |
| 5- | methyl quinoxaline | FL/FR |
| 2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| 2,3,5- | trimethyl pyrazine | FL/FR |
| popcorn |
| 2- | acetyl pyrazine | FL/FR |
| sulfurous |
| | benzothiazole | FL/FR |
| | furfuryl thioacetate | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| O- | methyl S-1-methoxyhexan-3-yl carbonothioate | FL/FR |
| vegetable |
| 1- | furfuryl pyrrole | FL/FR |
| | tetrahydrofurfuryl alcohol | FL/FR |
| woody |
| | juniper berry oleoresin | FL/FR |
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| For Flavor |
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| No flavor group found for these |
| 2,5- | dimethyl-3-thiofuroyl furan | FL |
| 2- | ethyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| 2- | methyl-3-,5 or 6-(furfuryl thio) pyrazine | FL/FR |
| absinthe |
| | absinthe flavor | FL |
| alliaceous |
| | benzyl mercaptan | FL |
| | dicyclohexyl disulfide | FL |
| | tropical thiazole | FL/FR |
| bitter |
| 2- | hydroxymethyl-6-methyl-pyridine | |
| brown |
| | fenugreek oleoresin | FL/FR |
| 1- | hydroxy-2-butanone | FL/FR |
| burnt |
| | furfuryl alcohol | FL |
| 1-(2- | furfuryl thio) propanone | FL |
| 2- | methyl quinoxaline | FL |
| iso | propenyl pyrazine | FL/FR |
| 2-( | thienyl-2)-ethanethiol | |
| 2,6- | xylenol | FL/FR |
| caramellic |
| | caramel furanone | FL |
| | cyclotene | FL/FR |
| | fenugreek absolute | FL/FR |
| | fenugreek distillates | FL |
| chocolate |
| | mocha cream flavor | FL |
| cocoa |
| | cocoa hexenal | FL/FR |
| 2- | methyl furan | FL |
| coffee |
| | cappuccino flavor | FL |
| | chicory flavor | FL |
| | chicory root | |
| | chicory root distillates | FL |
| | chicory root essence | FL |
| roasted | chicory root oil | FL |
| | chicory tincture | FL |
| | cichorium intybus root extract | FL/FR |
| | cichorium intybus root solid extract | FL/FR |
| | coffea arabica seed extract | FL/FR |
| roasted | coffea arabica seed extract | FL/FR |
| | coffea arabica seed oil | FL/FR |
| | coffea canephora seed extract | FL |
| | coffee absolute | FL/FR |
| arabica | coffee bean butter | FL/FR |
| roasted | coffee bean concentrate | FL |
| roasted | coffee bean essence | FL |
| roasted robusta | coffee bean essence | FL |
| roasted arabica | coffee bean essence | FL/FR |
| dried roasted | coffee bean extract | FL |
| roasted robusta | coffee bean extract | FL |
| roasted | coffee bean extract | FL/FR |
| roasted arabica | coffee bean oil CO2 extract | FL/FR |
| | coffee bean oil extract | FL/FR |
| | coffee creme brulee flavor | FL |
| | coffee difuran | FL/FR |
| | coffee dione | FL/FR |
| espresso | coffee distillates | FL |
| | coffee distillates | FL |
| | coffee enhancers | FL |
| espresso | coffee essence | FL |
| espresso | coffee extract | FL |
| | coffee flavor | FL |
| dark roast | coffee flavor | FL |
| espresso | coffee flavor | FL |
| irish | coffee flavor | FL |
| | coffee liqueur flavor | FL |
| | coffee pyrazine | FL |
| | coffee resinoid | FL/FR |
| | coffee royale flavor | FL |
| | difurfuryl ether | FL |
| | diisoamyl thiomalate | FL |
| 3,6- | dimethyl pyrazine-2-thiol | |
| 2,4- | dimethyl thiazole | FL |
| 2,5- | dimethyl-3-furfurylthio-pyrazine | |
| 2,5- | dimethyl-3,6-diethyl pyrazine | |
| 2- | ethyl-4-methyl thiazole | FL/FR |
| | furfuryl mercaptan | FL/FR |
| | methyl furfuryl disulfide | FL/FR |
| | methyl furfuryl mercaptopropionate | FL |
| 2- | methyl-5-vinyl pyrazine | FL |
| 2-iso | propyl pyrazine | FL |
| 2- | thiophene thiol | FL |
| dairy |
| | creme brulle coffee flavor | FL |
| earthy |
| | difurfuryl sulfide | FL |
| fruity |
| | furfuryl propionate | FL |
| fusel |
| 2- | methyl butyraldehyde | FL/FR |
| green |
| 3,4- | dimethoxystyrene | FL |
| 2,6- | dimethyl-gamma-thiopyrone | |
| 2- | methyl-5-isopropyl pyrazine | FL |
| 2-(1- | propenyl) pyridine | |
| hazelnut |
| 4- | hydroxymethyl-pyridine | |
| malty |
| | malt flavor | FL |
| meaty |
| | benzothiazole | FL/FR |
| 2,6- | dimethyl pyrazine | FL/FR |
| 3- | mercapto-2-butanone | FL |
| 2- | methyl 3-(methyl thio) furan | FL |
| mustard |
| | furfuryl methyl ether | FL |
| musty |
| 2- | ethoxythiazole | FL |
| | menthofuran | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| | thymyl methyl ether | FL/FR |
| 2,3,5- | trimethyl pyrazine | FL/FR |
| nutty |
| 2- | acetyl furan | FL/FR |
| 3,5- | cocoa pyrazine | FL/FR |
| 3,5(6)- | cocoa pyrazine | FL |
| 2,3- | dimethyl pyrazine | FL/FR |
| 4,5- | dimethyl-2-ethyl-3-thiazoline | FL/FR |
| | filbert heptenone | FL/FR |
| | hazelnut flavor | FL |
| | hazelnut paste | FL |
| 2,6- | lutidine | FL/FR |
| 5- | methyl quinoxaline | FL/FR |
| 2- | methyl thio-3,5 or 6-methyl pyrazine | FL/FR |
| 2- | methyl-3-pentyl pyrazine | |
| | nutty pyrazine | FL/FR |
| | nutty thiazole | FL |
| | tetrahydrofurfuryl alcohol | FL/FR |
| 2,3,5,6- | tetramethyl pyrazine | FL/FR |
| 2,4,5- | trimethyl thiazole | FL/FR |
| onion |
| | furfuryl isopropyl sulfide | FL |
| phenolic |
| 2- | pentenyl furan | |
| roasted |
| 2- | acetyl pyrazine | FL/FR |
| roasted arabica | coffee bean oil | FL/FR |
| 2,6- | dimethyl-thio-gamma-pyrone | |
| | ethyl 3-(furfuryl thio) propionate | FL |
| | furfuryl thioacetate | FL/FR |
| O- | methyl S-1-methoxyhexan-3-yl carbonothioate | FL/FR |
| smoky |
| dextro- | xylose | FL |
| spicy |
| | cinnamon hazelnut cappuccino flavor | FL |
| sulfurous |
| | butyl mercaptan | FL |
| | ethyl methyl sulfide | FL |
| S- | ethyl thioacetate | FL |
| | furfuryl thiopropionate | FL |
| 3- | methyl-2-butane thiol | FL |
| 2- | thienyl mercaptan | FL |
| vegetable |
| 1- | furfuryl pyrrole | FL/FR |
| woody |
| | juniper berry oleoresin | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2- | furan methane thiol formate | | S-( | furan-2-ylmethyl) methanethioate | | 2- | furanmethanethiol formate | | 2-2- | furanmethanethiol formate | | 2- | furanmethanethiolformate | | 3-(2- | furanyl methyl) methane thioate | | S-(2- | furanyl methyl) methane thioate | | 3-(2- | furanylmethyl) methanethioate | | | furfuryl thioformate | | | furfuryl thioformate (2-furanmethanethiol formate) | | | furfuryl thiol formate | | | furfurylthioformate | | | furfurylthiol butyrate | | | furfurylthiol formate | | 2- | furyl methyl sulfanyl formaldehyde | | | methane thioic acid 3-(2-furanyl methyl) ester | | | methane thioic acid S-(2-furanyl methyl) ester | | | methanethioic acid, 3-(2-furanylmethyl) ester | | | methanethioic acid, S-(2-furanylmethyl) ester |
Articles:
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