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Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 99.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.83900 to 0.84100 @ 20.00 °C.
|
| Pounds per Gallon - (est).: | 6.989 to 7.006
|
| Refractive Index: | 1.45100 to 1.45400 @ 20.00 °C.
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| Melting Point: | -76.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 182.00 to 189.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 1.200000 mmHg @ 25.00 °C. |
| Vapor Density: | 5.07 ( Air = 1 ) |
| Flash Point: | 165.00 °F. TCC ( 73.89 °C. )
|
| logP (o/w): | 4.034 (est) |
| Soluble in: |
| | alcohol | | | ethyl ether | | | water, 39.35 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: alliaceous |
| |
| Odor Strength: | high , recommend smelling in a 0.10 % solution or less |
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| Substantivity: | 20 hour(s) at 100.00 % |
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| | green grassy violet leaf herbal rose geranium |
Odor Description: at 0.10 % in dipropylene glycol. | green grassy violet-leaf herbal rose geranium Luebke, William tgsc, (1989) |
| |
| | onion garlic horseradish rubbery savory vegetable |
Odor Description: at 1.00 %. | Onion garlic, horseradish, rubbery, savory and vegetative Mosciano, Gerard P&F 24, No. 2, 49, (1999) |
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| |
| Flavor Type: green |
| |
| | green vegetable onion garlic horseradish savory |
Taste Description: at 5.00 ppm. | Green, vegetative, onion garlic, horseradish, savory Mosciano, Gerard P&F 24, No. 2, 49, (1999) |
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| Odor and/or flavor descriptions from others (if found). |
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| R C Treatt & Co Ltd |
| Dibutyl Sulphide Halal, Kosher |
| Odor Description: | floral/violet, green leaf, herbaceous, onion/garlic |
| Taste Description: | green Used in flavours for soft confection and bakery at 0.6ppm, and for desserts, beverages, and frozen dairy at 0.4ppm. Also used in fragrances as a natural green note in geranium and violet bases. |
| |
| Ernesto Ventós |
| BUTYL SULPHIDE |
| Odor Description: | ALLIACEOUS,GREEN,VIOLET,HERBACEOUS |
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| |
Cosmetic Information:
Suppliers:
| Ambles Nature et Chimie |
| DIBUTYL SULFIDE
|
| Beijing Lys Chemicals |
| Dibutyl sulfide
|
| Berjé |
| Dibutyl Sulfide
|
| Media |
| BOC Sciences |
| For experimental / research use only. |
| Butyl Sulfide 98%
|
| Charkit Chemical |
| BUTYL SULPHIDE FEMA 2215
|
| DeLong Chemicals America |
| Dibutyl sulfide, Kosher
|
| EMD Millipore |
| For experimental / research use only. |
| Dibutyl Sulfide
|
| Endeavour Specialty Chemicals |
| Dibutyl sulphide
|
| Speciality Chemical Product Groups |
| Ernesto Ventós |
| BUTYL SULPHIDE
Odor: ALLIACEOUS,GREEN,VIOLET,HERBACEOUS |
| Frutarom |
| BUTYL SULPHIDE
KOSHER Flavor: Alliaceous, Grassy, Green, Leafy, Herbal, Garlic |
| CBD Offering |
| IFF |
| BUTYL SULPHIDE
KOSHER Flavor: Alliaceous, Grassy, Green, Leafy, Herbal, Garlic |
| Jiangyin Healthway |
| Dibutyl sulphide
|
| New functional food ingredients |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| Dibutyl sulfide, Kosherk
|
| M&U International |
| DIBUTYL SULFIDE, Kosher
|
| Penta International |
| DIBUTYL SULFIDE
|
| R C Treatt & Co Ltd |
| Dibutyl Sulphide 1% in TEC
Kosher |
| R C Treatt & Co Ltd |
| Dibutyl Sulphide
Halal, Kosher Odor: floral/violet, green leaf, herbaceous, onion/garlic Flavor: green Used in flavours for soft confection and bakery at 0.6ppm, and for desserts, beverages, and frozen dairy at 0.4ppm. Also used in fragrances as a natural green note in geranium and violet bases. |
| Robinson Brothers |
| Dibutyl sulphide
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| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Dibutyl sulfide
|
| Sigma-Aldrich |
| Butyl sulfide, ≥95%, FG
Odor: green; herbaceous; alliaceous (onion, garlic). |
| Certified Food Grade Products |
| Sunaux International |
| Dibutyl Sulfide
|
| Synerzine |
| Dibutyl Sulfide
|
| Taytonn ASCC |
| Butyl Sulphide
Odor: Floral, Alliaceous, Green |
| TCI AMERICA |
| For experimental / research use only. |
| Butyl Sulfide >98.0%(GC)
|
| Tengzhou Jitian Aroma Chemiclal |
| Dibutyl Sulfide
|
| Tengzhou Xiang Yuan Aroma Chemicals |
| Dibutyl Sulfide
|
| Tianjin Danjun International |
| Butyl sulfide
|
| United International |
| Dibutyl Sulfide
|
| WholeChem |
| Dibutyl sulfide
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Human Experience: |
| 8 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 2220 mg/kg (Moreno, 1975g)
oral-rat LD50 2220 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 769, 1979.
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| Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 765, 1979.
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for dibutyl sulfide usage levels up to: | | | 0.1000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 2.30 (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | 0.03000 | 1.00000 |
| beverages(nonalcoholic): | 0.02000 | 1.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 0.01000 | 1.00000 |
| fruit ices: | 0.01000 | 1.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | 0.03000 | 1.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on the safety and efficacy of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups (chemical group 20) when used as flavourings for all animal species View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 544-40-1 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 11002 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| | 1-butylsulfanylbutane |
| Chemidplus: | 0000544401 |
| RTECS: | ER6417000 for cas# 544-40-1 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| alliaceous |
| | dipropyl disulfide | FL/FR |
| 1,3- | dithiane | |
| | methyl furfuryl disulfide | FL/FR |
| caramellic |
| 2-iso | butyl-3-methyl pyrazine | FL/FR |
| chocolate |
| 2,4,5- | trimethyl thiazole | FL/FR |
| citrus |
| | lemongrass oil | FL/FR |
| | litsea cubeba fruit oil | FL/FR |
| | methyl heptenone | FL/FR |
| coumarinic |
| | phthalide | FL/FR |
| ethereal |
| 2- | methyl valeraldehyde | FL/FR |
| fermented |
| | ethyl (E)-2-crotonate | FL/FR |
| floral |
| | mimosa absolute | FL/FR |
| | mimosa absolute france | FL/FR |
| | mimosa absolute india | FL/FR |
| | mimosa absolute morocco | FL/FR |
| (Z)- | rose oxide | FL/FR |
| fruity |
| | butyl 2-methyl butyrate | FL/FR |
| (Z)-3- | hexen-1-yl isobutyrate | FL/FR |
| 2- | methyl-2-pentenal | FL/FR |
| | prenyl ethyl ether | FL/FR |
| green |
| | acetaldehyde butyl phenethyl acetal | FL/FR |
| | alfalfa absolute | FR |
| | alfalfa oil | FL/FR |
| | alfalfa resinoid | FL/FR |
| | bark carbaldehyde | FR |
| | butyl heptanoate | FL/FR |
| iso | butyl methyl ketone | FL/FR |
| 2-iso | butyl thiazole | FL/FR |
| sec- | butyl-3-methyl but-2-ene thioate | FL/FR |
| | cortex pyridine | FL/FR |
| 3,7- | dimethyl-6-octenoic acid | FL/FR |
| | galbanum decatriene | FL/FR |
| | green specialty | FR |
| (Z)-3- | hepten-1-ol | FL/FR |
| 3- | hepten-2-one | FL/FR |
| | heptyl heptanoate | FL/FR |
| | hexanal dihexyl acetal | FL/FR |
| (Z)-2- | hexen-1-ol | FL/FR |
| (Z)-3- | hexen-1-ol | FL/FR |
| (Z)-3- | hexen-1-yl tiglate | FL/FR |
| (Z)-3- | hexenal | FL/FR |
| | hexyl butyrate | FL/FR |
| | hexyl hexanoate | FL/FR |
| (Z)- | leaf acetal | FL/FR |
| | lilac acetaldehyde | FL/FR |
| | methyl heptine carbonate | FL/FR |
| | nerol oxide | FL/FR |
| (Z,Z)-3,6- | nonadien-1-ol | FL/FR |
| | oakmoss resin | FR |
| 1- | penten-3-ol | FL/FR |
| | propylene acetal | FL/FR |
| 3,5,5- | trimethyl hexanol | FL/FR |
| herbal |
| iso | amyl heptanoate | FL/FR |
| 3- | butylidene phthalide | FL/FR |
| | clary sage resin america | FR |
| | geranium concrete | FL/FR |
| | geranyl octanoate | FL/FR |
| | oregano specialty | FR |
| minty |
| (-)-iso | pulegol | FL/FR |
| iso | pulegol | FL/FR |
| musty |
| | cocoa butenal | FL/FR |
| spicy |
| | ethyl vinyl ketone | FL/FR |
| 3-(2- | furyl) acrolein | FL/FR |
| | gingergrass oil | FR |
| | ethyl 2-mercaptopropionate | FL/FR |
| | ethyl methyl mercaptopropionate | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| 3-( | methyl thio) hexanol | FL/FR |
| 4- | methyl-1,3-dithiane | |
| vegetable |
| 1- | furfuryl pyrrole | FL/FR |
| woody |
| alpha- | farnesene | FL/FR |
| alpha- | farnesene isomer | FL/FR |
| yeasty |
| 2- | octen-4-one | FL/FR |
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| For Flavor |
| |
| No flavor group found for these |
| 2- | acetyl-4-isopropenyl pyridine | FL |
| 2- | acetyl-4-isopropyl pyridine | FL |
| sec- | butyl-3-methyl but-2-ene thioate | FL/FR |
| 2- | ethyl pyridine | FL |
| 3-(2- | furyl) acrolein | FL/FR |
| | geranyl octanoate | FL/FR |
| 2- | heptenoic acid | FL |
| | hexanal dihexyl acetal | FL/FR |
| (Z)-3- | hexenoic acid | FL |
| 3-( | methyl thio) hexanal | FL |
| (E,E)-3,5- | octadien-2-one | FL |
| | prenyl ethyl ether | FL/FR |
| | propylene acetal | FL/FR |
| alliaceous |
| | allyl disulfide | FL |
| | allyl thiopropionate | FL |
| | cyclopentyl mercaptan | FL |
| | dipropyl disulfide | FL/FR |
| 2- | methyl thioacetaldehyde | FL |
| 3- | tetrahydrothiophenone | FL |
| | truffle sulfide | FL |
| celery |
| 3- | butylidene phthalide | FL/FR |
| citrus |
| | lemongrass oil | FL/FR |
| | litsea cubeba fruit oil | FL/FR |
| coffee |
| | methyl furfuryl disulfide | FL/FR |
| coumarinic |
| | phthalide | FL/FR |
| creamy |
| 3- | hepten-2-one | FL/FR |
| floral |
| 3,7- | dimethyl-6-octenoic acid | FL/FR |
| | mimosa absolute morocco | FL/FR |
| fruity |
| | butyl 2-methyl butyrate | FL/FR |
| | butyl heptanoate | FL/FR |
| 2,4- | hexadien-1-ol | FL |
| (Z)-3- | hexen-1-yl isobutyrate | FL/FR |
| | hexyl hexanoate | FL/FR |
| | lilac acetaldehyde | FL/FR |
| 2- | methyl-2-pentenal | FL/FR |
| green |
| | acetaldehyde butyl phenethyl acetal | FL/FR |
| | alfalfa oil | FL/FR |
| | alfalfa resinoid | FL/FR |
| iso | butyl methyl ketone | FL/FR |
| 2-iso | butyl thiazole | FL/FR |
| 2-iso | butyl-3-methyl pyrazine | FL/FR |
| | cocoa butenal | FL/FR |
| | cortex pyridine | FL/FR |
| | dihydroxyacetophenone (mixed isomers) | FL |
| alpha- | farnesene | FL/FR |
| alpha- | farnesene isomer | FL/FR |
| | galbanum decatriene | FL/FR |
| (Z)-3- | hepten-1-ol | FL/FR |
| | heptyl heptanoate | FL/FR |
| (Z)-2- | hexen-1-ol | FL/FR |
| (Z)-3- | hexen-1-ol | FL/FR |
| (Z)-3- | hexen-1-yl tiglate | FL/FR |
| (Z)-3- | hexenal | FL/FR |
| | hexyl butyrate | FL/FR |
| 2- | hexyl pyridine | FL |
| | horseradish oil | FL |
| (Z)- | leaf acetal | FL/FR |
| | methyl heptenone | FL/FR |
| | methyl heptine carbonate | FL/FR |
| 4- | methyl thiazole | FL |
| | nerol oxide | FL/FR |
| 4- | penten-1-yl acetate | FL |
| 1- | penten-3-ol | FL/FR |
| (Z)- | rose oxide | FL/FR |
| 3,5,5- | trimethyl hexanol | FL/FR |
| herbal |
| iso | amyl heptanoate | FL/FR |
| | geranium concrete | FL/FR |
| meaty |
| (R,S)-2- | mercapto-3-butanol | FL |
| bis(2- | methyl-3-furyl) disulfide | FL |
| ortho- | thiocresol | FL |
| metallic |
| 3-( | methyl thio) hexanol | FL/FR |
| minty |
| iso | pulegol | FL/FR |
| (-)-iso | pulegol | FL/FR |
| musty |
| | ethyl (E)-2-crotonate | FL/FR |
| 2- | methyl 5-(methyl thio) furan | FL/FR |
| nutty |
| 2,4,5- | trimethyl thiazole | FL/FR |
| onion |
| 1,3- | dithiane | |
| | ethyl 2-mercaptopropionate | FL/FR |
| | methionol | FL |
| | methyl propyl disulfide | FL |
| | methyl propyl trisulfide | FL |
| | propyl thioacetate | FL |
| seafood |
| 1,4- | dithiane | FL |
| spicy |
| | ethyl vinyl ketone | FL/FR |
| sulfurous |
| | allyl sulfide | FL |
| | butyl mercaptan | FL |
| | ethyl methyl mercaptopropionate | FL/FR |
| S- | ethyl thioacetate | FL |
| | furfuryl thiopropionate | FL |
| 3- | mercapto-2-methyl pentanal | FL |
| | methyl 2-(methyl thio) butyrate | FL |
| | methyl thiomethyl butyrate | FL |
| 4- | methyl-1,3-dithiane | |
| vegetable |
| 1- | furfuryl pyrrole | FL/FR |
| 2- | methyl valeraldehyde | FL/FR |
| 2- | octen-4-one | FL/FR |
| waxy |
| | mimosa absolute | FL/FR |
| | mimosa absolute france | FL/FR |
| | mimosa absolute india | FL/FR |
| (Z,Z)-3,6- | nonadien-1-ol | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | butane, 1,1'-thiobis- | | | butyl monosulfide | | | butyl sulphide (dibutyl sulphide) | | | butyl thiobutane | | 1-( | butylsulfanyl)butane | | 1- | butylsulfanylbutane | | 1-( | butylthio)butane | | | butylthiobutane | | | di-N-butyl sulfide | | | di-N-butylsulfide | | N- | dibutyl sulfide | | | dibutyl sulphide | | | dibutyl thioether | | 5- | thianonane | | 1,1'- | thiobis(butane) | | 1,1'- | thiobisbutane | | 1,1'- | thiodibutane | | | thiononane-5 |
Articles:
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