Articles:
1,2-ethanedithiol
Notes:
Present in cooked chicken and beef. Flavouring ingredient
1,2-Ethanedithiol is an odorous, colorless liquid with the formula C2H4(SH)2. It has a very characteristic odour which is compared by many people to rotten cabbage. It is a common building block in organic synthesis and an excellent ligand for metal ions.
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 540-63-6 Ethylene Mercaptan
-
-
Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 05-06600 1,2-ETHANEDITHIOL
-
-
Robinson Brothers Limited Providing Excellence in Chemistry Award-winning UK chemical manufacturer of chemical intermediates and high-impact aroma chemicals. Based in the UK, Robinson Brothers is an award-winning chemical manufacturer of chemical intermediates and high-impact aroma chemicals. Robinson Brothers serve many industry sectors across the globe, include: flavour/fragrance, pharmaceutical, agrochemical and material sciences. Our team of Chemists are experts in custom synthesis, contract manufacture and process optimisation. Email: Info Email: Sales Voice: +44 (0)121 553 2451 Fax: +44 (0)121 500 5183 Twitter Linkedin News And Exhibitions Custom Synthesis Industries And Applications https://www.robinsonbrothers.uk/chemistry-competences Products List: View Product(s): SV2258 1,2-Ethanedithiol F&F
-
-
Synerzine, Inc. Innovation. Customization. Aroma Ingredients. Synerzine is a leading supplier of flavor and fragrance ingredients. Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust. Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster. US Email: Customer Service US Email: Sales US Voice: (404) 524-6744 US Fax: (404) 577-1651 Inquiry Products List: View Product(s): W0543 1,2-Ethanedithiol
-
-
TCI AMERICA Moving Your Chemistry Forward We continuously strive to advance our technology. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping! Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis. US Email: Sales Email: Technical Support Voice: 1-800-423-8616 Fax: 1- 888-520-1075 Facebook Twitter Instagram Linkedin Product(s): E0032 1,2-Ethanedithiol >99.0%(GC)
-
-
WholeChem, LLC Connecting Innovators To the Building Blocks Of the Universe Custom manufacturer and distributor of specialty ingredients. We make global local. SQF-Certified Supplier We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing. Email: Info Email: Orders Voice: +1 (262) 995.8668 Certification Our Services Products List: View Product(s): 1,2-Ethanedithiol
-
| CAS Number: | 540-63-6 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 208-752-3 | |
| FDA UNII: | 92T634FLAR | |
| Nikkaji Web: | J4.507A | |
| Beilstein Number: | 0505946 | |
| MDL: | MFCD00004892 | |
| CoE Number: | 11467 | |
| XlogP3-AA: | 0.80 (est) | |
| Molecular Weight: | 94.19982000 | |
| Formula: | C2 H6 S2 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 532 1,2-ethanedithiol |
| DG SANTE Food Flavourings: | 12.066 ethane-1,2-dithiol |
| FEMA Number: | 3484 1,2-ethanedithiol |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 540-63-6 ; 1,2-ETHANEDITHIOL |
Physical Properties:
| Appearance: | colorless to pale green clear liquid (est) |
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.12300 to 1.12400 @ 20.00 °C. |
| Pounds per Gallon - (est).: | 9.355 to 9.364 |
| Refractive Index: | 1.55800 to 1.55900 @ 20.00 °C. |
| Melting Point: | -41.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 144.00 to 146.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 46.00 to 47.00 °C. @ 6.00 mm Hg |
| Vapor Pressure: | 5.610000 mmHg @ 25.00 °C. |
| Vapor Density: | >1 ( Air = 1 ) |
| Flash Point: | 122.00 °F. TCC ( 50.00 °C. ) |
| logP (o/w): | 1.310 (est) |
| Soluble in: | |
| fats | |
| water, 1.122e+004 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| Similar Items: note | |
| allyl mercaptan | |
| amyl mercaptan | |
| isoamyl mercaptan | |
| sec-amyl mercaptan | |
| tert-amyl mercaptan | |
| benzyl mercaptan | |
| buchu mercaptan | |
| butyl mercaptan | |
| isobutyl mercaptan | |
| tert-butyl mercaptan | |
| cetyl mercaptan | |
| cyclohexyl mercaptan | |
| cyclopentyl mercaptan | |
| decyl mercaptan | |
| dodecyl mercaptan | |
| 2-ethyl hexyl mercaptan | |
| ethyl mercaptan | |
| furfuryl mercaptan | |
| grapefruit mercaptan | |
| heptyl mercaptan | |
| hexyl mercaptan | |
| methyl mercaptan | |
| 2-naphthyl mercaptan | |
| nonyl mercaptan | |
| octyl mercaptan | |
| peach mercaptan | |
| 1-phenethyl mercaptan | |
| 2-phenethyl mercaptan | |
| phenyl mercaptan | |
| prenyl mercaptan | |
| propyl mercaptan | |
| isopropyl mercaptan | |
| 2-thienyl mercaptan | |
| 3-thienyl mercaptan | |
| tridecyl mercaptan | |
| undecyl mercaptan | |
Organoleptic Properties:
| Odor Type: sulfurous | |
| sulfurous meaty | |
| Odor Description: at 0.01 % in propylene glycol. | sulfury meaty |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Ethylene Mercaptan |
| EMD Millipore |
| For experimental / research use only. |
| 1,2-Ethanedithiol |
| Penta International |
| 1,2-ETHANEDITHIOL |
| Robinson Brothers |
| 1,2-Ethanedithiol F&F |
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 1,2-Ethanedithiol |
| Sigma-Aldrich |
| For experimental / research use only. |
| 1,2-Ethanethiol purum, ≥98.0% (GC) |
| Synerzine |
| 1,2-Ethanedithiol |
| TCI AMERICA |
| For experimental / research use only. |
| 1,2-Ethanedithiol >99.0%(GC) |
| Tengzhou Jitian Aroma Chemiclal |
| Ethylene Mercaptan |
| WholeChem |
| 1,2-Ethanedithiol |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| T - Toxic. | |
|
R 10 - Flammable. R 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 23 - Do not breath vapour. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. S 45 - In case of accident or if you feel unwell seek medical advice immediately. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 [sex: M,F] 144 mg/kg (Phillips Petroleum Company, 1990b) oral-rat LD50 [sex: M,F] 342 mg/kg (Moran et al., 1980) gavage-mouse LD50 [sex: M,F] 342 mg/kg (Fogleman & DeProspo, 1974) oral-mouse LD50 120 mg/kg (Pharmacology Research, Inc., 1963) oral-rat LD50 [sex: M,F] 218 mg/kg (Phillips Petroleum Company, 1990b) intraperitoneal-mouse LD50 50 mg/kg European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 235, 1982. intravenous-mouse LD50 56200 ug/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02101 oral-mouse LD50 342 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for ethylene mercaptan usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.0012 (μg/capita/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 10 | |||
| Click here to view publication 10 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 0.20000 | |
| beverages(nonalcoholic): | - | - | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | 0.20000 | |
| hard candy: | - | - | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | 0.20000 | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | 0.20000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf | |
| Flavouring Group Evaluation 74 (FGE.74)[1]: Consideration of Simple Aliphatic Sulphides and Thiols evaluated by JECFA (61st meeting) Structurally related to Aliphatic and Alicyclic Mono-, Di-, Tri-, and Polysulphides with or without Additional Oxygenated Functional Groups from Chemical Group 20 evaluated by EFSA in FGE.08 (2008) View page or View pdf | |
| Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf | |
| Flavouring Group Evaluation 91 (FGE.91): Consideration of simple aliphatic and aromatic sulphides and thiols evaluated by JECFA (53rd and 68th meetings) structurally related to aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups evaluated by EFSA in FGE.08Rev1 (2009) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 540-63-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 10902 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 3071 |
| WGK Germany: | 3 |
| ethane-1,2-dithiol | |
| Chemidplus: | 0000540636 |
| RTECS: | KI3325000 for cas# 540-63-6 |
References:
| ethane-1,2-dithiol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 540-63-6 |
| Pubchem (cid): | 10902 |
| Pubchem (sid): | 134975737 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB31707 |
| FooDB: | FDB008370 |
| Export Tariff Code: | 2930.90.9190 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| FAO: | 1,2-Ethanedithiol |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| beef boiled beef Search PMC Picture | |
| chicken cooked chicken Search PMC Picture |
Synonyms:
| 1,2- | dimercaptoethane |
| dithioethylene glycol | |
| dithioethyleneglycol | |
| dithioglycol | |
| 1,2- | dithiol ethane |
| 1,2- | dithiolethane |
| 1,2- | ethane dithiol |
| ethane-1,2-dithiol | |
| ethanedithiol | |
| 1,2- | ethanedithiol |
| 1,2- | ethanethiol |
| ethylene dimercaptan | |
| S- | ethylene dimercaptan |
| ethylene dithioglycol |