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Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 98.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.13500 to 1.13800 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 9.444 to 9.469
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| Refractive Index: | 1.43200 to 1.43700 @ 20.00 °C.
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| Boiling Point: | 142.00 to 143.00 °C. @ 757.00 mm Hg
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| Boiling Point: | 38.00 to 40.00 °C. @ 12.00 mm Hg
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| Acid Value: | 1.00 max. KOH/g
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| Vapor Pressure: | 5.872000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 4.0 ( Air = 1 ) |
| Flash Point: | 94.00 °F. TCC ( 34.44 °C. )
|
| logP (o/w): | 1.878 (est) |
| Soluble in: |
| | alcohol | | | diethyl ether | | | oils | | | propylene glycol | | | water, 9515 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
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| Odor Type: cheesy |
| |
| | sulfurous cheesy cabbage garlic |
Odor Description: at 0.10 % in propylene glycol. | sulfury cheese putrid cabbage garlic |
| |
| | sulfurous eggy cheesy tomato fruit tropical fruit |
Odor Description: at 1.00 % in ethyl alcohol. | Sulfurous, egg and cheese notes, tomato, tropical-fruit top notes Mosciano, Gerard P&F 23, No. 6, 31, (1998) |
| |
| |
| Flavor Type: musty |
| |
| | musty sulfurous cheesy limburger cheese metallic cheesy |
Taste Description: at 5.00 ppm. | Musty, sulfureous, Limburger-type cheese top notes, metallic cheese body Mosciano, Gerard P&F 23, No. 6, 31, (1998) |
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| Odor and/or flavor descriptions from others (if found). |
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| Bedoukian Research |
| METHYL THIOBUTYRATE (10% IN TRIACETIN) ≥99.0%, Kosher |
| Odor Description: | powerful, sweet cheesy |
| Taste Description: | musty For use in cheese, tomato and for sulfury notes in other savory flavors. |
| |
| R C Treatt & Co Ltd |
| Methyl thio butyrate Halal, Kosher |
| Odor Description: | powerful sweet cheesy, cocoa odour on dilution |
| Taste Description: | cheesy Finds use in extreme dilution in cheese, berry and chocolate flavors. A combination of this material and isobutyraldehyde is similar to the aroma of cocoa distillate. Normal use levels in finished consumer product: 0.0005-0.5 ppm. Council of Europe limits: Foods (5 ppm). |
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Cosmetic Information:
Suppliers:
| Advanced Biotech |
| METHYL THIO BUTYRATE 5% ETOH NATURAL
|
| Advanced Biotech |
| METHYL THIOBUTYRATE 5% IN ETOH NATURAL
Odor: Alcoholic, Cabbage, Sour |
| Advanced Biotech |
| METHYL THIOBUTYRATE NATURAL
5% min. (in OS) Odor: Cabbage, Sour |
| Advanced Biotech |
| METHYL THIOBUTYRATE SYNTHETIC
|
| Alfrebro |
| Methyl Thiobutyrate, Natural
Odor: Sulfurous, Egg and Cheese Notes Tomato, Tropical-fruit Top notes |
| Ambles Nature et Chimie |
| METHYL THIOBUTYRATE
|
| Anhui Haibei |
| Methyl Thiobutyrate
Odor: Sulfury cheese putrid cabbage garlic |
| Aurochemicals |
| METHYL THIOBUTYRATE 10% IN ETOH, Natural
|
| Axxence Aromatic |
| METHYL THIOBUTYRATE 5% IN ETHANOL, Natural, Kosher
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| Sustainability |
| Axxence Aromatic |
| METHYL THIOBUTYRATE 98%, Natural, Kosher
|
| Beijing Lys Chemicals |
| Methyl thiobutyrate
|
| Berjé |
| Methyl Thio Butyrate
|
| Media |
| BOC Sciences |
| For experimental / research use only. |
| Methyl thiobutyrate
|
| Charkit Chemical |
| METHYL THIOBUTYRATE FEMA 3310
|
| Charkit Chemical |
| METHYL THIOBUTYRATE NATURAL FEMA 3310
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| DeLong Chemicals America |
| Methyl thiobutyrate, Kosher
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| Endeavour Specialty Chemicals |
| S-Methyl thiobutyrate 99% F&F
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| Speciality Chemical Product Groups |
| Ernesto Ventós |
| METHYL THIOBUTYRATE
Odor: PUTRID, CABBAGE |
| Excellentia International |
| Methyl ThioButyrate Natural
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| Frutarom |
| METHYL THIOBUTYRATE
KOSHER Flavor: Sulfurous, Cheesy, Cabbage, Garlic, Musty |
| CBD Offering |
| H. Interdonati, Inc. |
| Methyl thiobutyrate Kosher
|
| Featured Products |
| IFF |
| METHYL THIOBUTYRATE
KOSHER Flavor: Sulfurous, Cheesy, Cabbage, Garlic, Musty |
| Indenta Group |
| Methyl Thiobutyrate
|
| Indukern F&F |
| METHYL THIOBUTYRATE
Odor: POWERFUL, SULFUROUS, CHEESE, PUTRID |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| S-Methyl thiobutyrate Kosherk
|
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| S-Methyl Thiobutyrate
|
| Lluch Essence |
| METHYL THIOBUTYRATE NATURAL
|
| M&U International |
| METHYL THIOBUTYRATE, Kosher
|
| Natural Advantage |
| Methylthio Butyrate Nat, 5% in OH
Flavor: cheesy, fruity, sweet |
| Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries |
| Natural Advantage |
| Methylthio Butyrate Nat, 5% in PG
Flavor: cheesy, fruity, sweet |
| Natural Advantage |
| Methylthio Butyrate Nat
Flavor: cheesy, fruity, sweet |
| Penta International |
| METHYL THIOBUTYRATE NATURAL 5% IN ETOH
|
| Penta International |
| METHYL THIOBUTYRATE NATURAL
|
| Penta International |
| METHYL THIOBUTYRATE
|
| R C Treatt & Co Ltd |
| Methyl thio butyrate
Halal, Kosher Odor: powerful sweet cheesy, cocoa odour on dilution Flavor: cheesy Finds use in extreme dilution in cheese, berry and chocolate flavors. A combination of this material and isobutyraldehyde is similar to the aroma of cocoa distillate. Normal use levels in finished consumer product: 0.0005-0.5 ppm. Council of Europe limits: Foods (5 ppm). |
| Reincke & Fichtner |
| Methyl Thiobutyrate
|
| Riverside Aromatics |
| METHYL THIOBUTYRATE, NATURAL
|
| Riverside Aromatics |
| METHYL THIOBUTYRATE
|
| Robertet |
| METHYL THIOBUTYRATE
Pure & Nat (EU) |
| Seasons and Harvest / Crop calendar |
| Robinson Brothers |
| S-Methyl thiobutyrate F&F
|
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| S-Methyl thiobutanoate
|
| Sigma-Aldrich |
| Methyl thiobutyrate, ≥97%, FG
Odor: cheese; musty; alliaceous (onion, garlic); animal; vegetable |
| Certified Food Grade Products |
| Sigma-Aldrich |
| Methyl thiobutyrate, natural, 98%, FG
|
| SRS Aromatics |
| METHYL THIOBUTYRATE
|
| Sunaux International |
| Methyl Thiobutyrate
|
| Synerzine |
| Methylthiobutyrate
|
| Taytonn ASCC |
| Methyl Thiobutyrate
Odor: Cheese, Fruity, Powder/ Powdery, Rancid, Sweet |
| TCI AMERICA |
| For experimental / research use only. |
| S-Methyl Thiobutyrate >98.0%(GC)
|
| Tengzhou Jitian Aroma Chemiclal |
| S-Methyl thiobutyrate
|
| Tianjin Danjun International |
| Methyl thiobutyrate
|
| United International |
| Methyl thiobutyrate
|
| WholeChem |
| Methyl thiobutyrate
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 10 - Flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
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| Dermal Toxicity: |
|
Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for S-(methyl thio) butyrate usage levels up to: | | | 0.0300 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 2.90 (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 5 |
| Click here to view publication 5 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 7.00000 |
| beverages(nonalcoholic): | - | 0.00050 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 0.05000 |
| fruit ices: | - | 0.05000 |
| gelatins / puddings: | - | 0.06000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 0.50000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | 0.06000 |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 2432-51-1 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 62444 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 3272 |
| WGK Germany: | 3 |
| | S-methyl butanethioate |
| Chemidplus: | 0002432511 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | butanethioic acid S-methyl ester | | | butanethioic acid, S-methyl ester | | | butyric acid, thio-, S-methyl ester | | | cheese butyrate | | | methane thiol butyrate | | S- | methyl butane thioate | | S- | methyl butanethioate | | | methyl thio butyrate | | | methyl thio butyrate 5% in ethanol natural | | S-( | methyl thio) butanoate | | S- | methyl thiobutanoate | | | methyl thiobutyrate | | S- | methyl thiobutyrate | | | methyl thiobutyrate (10% in triacetin) | | | methyl thiobutyrate 5% in ETOH natural | | | methyl thiobutyrate natural | | | methyl thiobutyrate synthetic | | | methyl thiobutyrate, natural 5% in ETOH | | | methyl thiolbutyrate | | S-( | methylthio)butanoate | | S-( | methylthio)butyrate | | | methylthiobutyrate | | | methylthiol n-butyrate | | | thiobutyric acid methyl ester |
Articles:
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