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Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
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| Odor Type: ethereal |
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| Odor Strength: | high , recommend smelling in a 1.00 % solution or less |
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| Substantivity: | 4 hour(s) at 100.00 % |
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| | ethereal green alcoholic rose cognac |
Odor Description: at 1.00 % in dipropylene glycol. | ethereal green alcohol rose cognac Luebke, William tgsc, (1989) |
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| | ethereal fermented winey cognac |
Odor Description: at 2.00 %. | Etherial, lifting, fermented, winey and cognac Mosciano, Gerard P&F 23, No. 3, 55, (1998) |
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| Flavor Type: ethereal |
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| | ethereal sweet grain fruity winey cognac |
Taste Description: at 200.00 ppm. | Etherial, sweet, grainy, fruity, winey and cognac Mosciano, Gerard P&F 23, No. 3, 55, (1998) |
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| Odor and/or flavor descriptions from others (if found). |
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| Symrise |
| Ethyl formate |
| Odor Description: | strong, ethereal-fruity, like rum |
| Taste Description: | sweet, rum, fruity, baked fruit, whisky Useful in: mint, savory vegetable, fruity red, fruity yellow, fruity tropical, fruity others, sweet others, alcoholics. |
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| Moellhausen |
| ETHYL FORMATE |
| Odor Description: | sweet, ethereal-fruity |
| Taste Description: | sweet, fruity |
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| Prodasynth |
| ETHYL FORMATE (> 98%) |
| Odor Description: | FRUITY, RUM, STRONG, ETHEREAL |
| Taste Description: | SWEET,RUM,FRUITY,BAKED FRUIT,WHISKY |
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Cosmetic Information:
Suppliers:
| Advanced Biotech |
| ETHYL FORMATE NATURAL
90% min. Odor: Fruity |
| Alfrebro |
| ETHYL FORMATE NATURAL
Odor: Sharp, Sweet, Ethereal, Rum |
| Ambles Nature et Chimie |
| ETHYL FORMATE NAT
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| Aurochemicals |
| ETHYL FORMATE, Natural
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| Axxence Aromatic |
| ETHYL FORMATE Natural
Kosher |
| Sustainability |
| Berjé |
| Ethyl Formate
|
| Media |
| Charkit Chemical |
| ETHYL FORMATE FEMA 2434
|
| CJ Latta & Associates |
| ETHYL FORMATE
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| Diffusions Aromatiques |
| FORMIATE ETHYLE
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| Ernesto Ventós |
| ETHYL FORMATE, NATURAL
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| Ernesto Ventós |
| ETHYL FORMATE
Odor: FRUITY, RUM, STRONG, ETHEREAL Flavor: SWEET,RUM,FRUITY,BAKED FRUIT,WHISKY |
| Excellentia International |
| Ethyl Formate Natural
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| Fleurchem |
| ethyl formate natural
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| Glentham Life Sciences |
| Ethyl formate
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| Global Essence |
| Ethyl Formate Natural
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| H. Interdonati, Inc. |
| Ethyl formate Natural, Kosher
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| Featured Products |
| Indenta Group |
| Ethyl Formate
|
| Indukern F&F |
| ETHYL FORMATE
|
| K.L. Koh Enterprise |
| ETHYL FORMATE
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| Lluch Essence |
| ETHYL FORMATE NATURAL
|
| Lluch Essence |
| ETHYL FORMATE
Odor: FRUITY, SWEET, ETHEREAL |
| M&U International |
| Ethyl Formate
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| M&U International |
| NAT.ETHYL FORMATE, Kosher
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| Moellhausen |
| ETHYL FORMATE
Odor: sweet, ethereal-fruity Flavor: sweet, fruity |
| Nagar Haveli Perfumes & Aromatics |
| Ethyl Formate
Odor: Etherial, lifting, fermented, winey and cognac |
| Natural Advantage |
| Ethyl Formate Nat
Flavor: ethereal, fruity, rum |
| Riverside Aromatics LTD.is the exclusive distributor for Europe in UK for any non-US based inquiries |
| Pearlchem Corporation |
| Natural Ethyl Formate
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| Penta International |
| ETHYL FORMATE FCC
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| Penta International |
| ETHYL FORMATE NATURAL
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| Penta International |
| ETHYL FORMATE
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| Prodasynth |
| ETHYL FORMATE
(> 98%) Odor: FRUITY, RUM, STRONG, ETHEREAL Flavor: SWEET,RUM,FRUITY,BAKED FRUIT,WHISKY |
| R C Treatt & Co Ltd |
| Ethyl Formate
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| Reincke & Fichtner |
| Ethyl Formate natural
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| Reincke & Fichtner |
| Ethyl Formate
|
| Riverside Aromatics |
| ETHYL FORMATE, NATURAL
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| Robertet |
| Ethyl formate naturel
|
| Seasons and Harvest / Crop calendar |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Ethyl Formate ≥97%
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| Sigma-Aldrich |
| Ethyl formate, ≥97%, FCC, FG
Odor: ethereal; fruity; sweet; wine-like |
| Certified Food Grade Products |
| Sigma-Aldrich |
| Ethyl formate, natural, ≥95%, FG
Odor: ethereal; fruity; sweet; wine-like |
| Silverline Chemicals |
| Ethyl Formate
|
| SRS Aromatics |
| ETHYL FORMATE
|
| Sunaux International |
| nat.Ethyl Formate
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| SysKem Chemie |
| Ethyl Formate
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| Taytonn ASCC |
| Ethyl Formate
Odor: Diffusive, Ethereal, Fruity, Warm |
| TCI AMERICA |
| For experimental / research use only. |
| Ethyl Formate [for Spectrophotometry] >98.0%(GC)
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| The Lermond Company |
| ETHYL FORMATE
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| Ungerer & Company |
| Ethyl Formate
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| Vigon International |
| Ethyl Formate
Odor: Strong, ethereal-fruity, like rum |
| WEN International |
| ETHYL FORMATE Natural
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Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 11 - Highly flammable. R 20/22 - Harmful by inhalation and if swallowed. R 36/37 - Irritating to eyes and respiratory system. S 09 - Keep container in a well-ventilated place. S 16 - Keep away from sources of ignition - No Smoking. S 24 - Avoid contact with skin. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 33 - Take precautionary measures against static discharge.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Human Experience: |
| 4 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 1850 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
oral-rabbit LD50 2075 mg/kg Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
oral-guinea pig LD50 1110 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: GASTRITIS Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
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| Dermal Toxicity: |
skin-rabbit LD50 > 20 ml/kg AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
subcutaneous-rabbit LDLo 1000 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 737, 1978.
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| Inhalation Toxicity: |
inhalation-rat LCLo 8000 ppm/4H AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
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Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for ethyl formate usage levels up to: | | | 2.0000 % in the fragrance concentrate.
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| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 98.00000 |
| beverages(nonalcoholic): | - | 9.40000 |
| beverages(alcoholic): | - | 10.00000 |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | 430.00000 |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 21.00000 |
| fruit ices: | - | 21.00000 |
| gelatins / puddings: | 0.35000 | 11.00000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 50.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Authority (EFSA) reference(s): |
Flavouring Group Evaluation 2, Revision 1 (FGE.02) : Branched- and straight-chain aliphatic saturated primary alcohols and related esters of primary alcohols and straight-chain carboxylic acids and one straight-chain aldehyde from chemical groups 1 and 2 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
Scientific Opinion on the safety and efficacy of straight-chain primary aliphatic alcohols/aldehydes/acids, acetals and esters with esters containing saturated alcohols and acetals containing saturated aldehydes (chemical group 1) when used as flavourings for all animal species View page or View pdf |
| EPI System: | View |
| NIOSH International Chemical Safety Cards: | search |
| NIOSH Pocket Guide: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 109-94-4 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 8025 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 1190 |
| WGK Germany: | 1 |
| | ethyl formate |
| Chemidplus: | 0000109944 |
| EPA/NOAA CAMEO: | hazardous materials |
| RTECS: | 109-94-4 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | areginal | | | carboxylic acid oxaethane | | | ethyl ester of formic acid | | nat. | ethyl formate | | | ethyl formate (natural) | | | ethyl formate FCC | | | ethyl formate natural | | | ethyl formate naturel | | | ethyl formic ester | | | ethyl methanoate | | | formic acid ethyl ester | | | formic ether |
Articles:
| Info: | Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.) |
| PubMed: | Postharvest control of western flower thrips (Thysanoptera: Thripidae) and California red scale (Hemiptera: Diaspididae) with ethyl formate and its impact on citrus fruit quality. |
| PubMed: | Ethyl formate plus methyl isothiocyanate--a potential liquid fumigant for stored grains. |
| PubMed: | Effect of ionization on infrared and electronic absorption spectra of methyl and ethyl formate in the gas phase and in astrophysical H2O ice: a computational study. |
| PubMed: | Efficacy of vaporised ethyl formate/carbon dioxide formulation against stored-grain insects: effect of fumigant concentration, exposure time and two grain temperatures. |
| PubMed: | Field evaluation of vaporised ethyl formate and carbon dioxide for fumigation of stored wheat. |
| PubMed: | Modelling the kinetics of ethyl formate sorption by wheat using batch experiments. |
| PubMed: | The aromatic character of thienopyrrole-modified 20Ï€-electron porphyrinoids. |
| PubMed: | Identification of ethyl formate as a quality marker of the fermented off-note in coffee by a nontargeted chemometric approach. |
| PubMed: | Fumigation of wheat using liquid ethyl formate plus methyl isothiocyanate in 50-tonne farm bins. |
| PubMed: | Improved efficacy of ethyl formate against stored grain insects by combination with carbon dioxide in a 'dynamic' application. |
| PubMed: | Ethyl formate - alternative dispersed solvent useful in preparing PLGA microspheres. |
| PubMed: | Isomer-specific fuel destruction pathways in rich flames of methyl acetate and ethyl formate and consequences for the combustion chemistry of esters. |
| PubMed: | Ethyl formate as a postharvest fumigant for selected pests of table grapes. |
| PubMed: | The proton inventory technique in a dual mechanistic system: the spontaneous hydrolysis of ethyl formate. |
| PubMed: | Evaluation of microwave irradiation for analysis of carbonyl sulfide, carbon disulfide, cyanogen, ethyl formate, methyl bromide, sulfuryl fluoride, propylene oxide, and phosphine in hay. |
| PubMed: | Experimental and modeling study of the thermal decomposition of C3-C5 ethyl esters behind reflected shock waves. |
| PubMed: | BF3·Et2O-Catalyzed Formal [3 + 2] Reaction of Aziridinofullerenes with Carbonyl Compounds. |
| PubMed: | [Study on quality standard of Selaginella moellendorffii]. |
| PubMed: | A systematic approach for optimizing the robustness of pulse sequence elements with respect to couplings, offsets, and B1-field inhomogeneities (COB). |
| PubMed: | Zinc catalysts for on-demand hydrogen generation and carbon dioxide functionalization. |
| PubMed: | Novel series of 17β-pyrazolylandrosta-5,16-diene derivatives and their inhibitory effect on 17α-hydroxylase/C(17,20)-lyase. |
| PubMed: | Molecular analysis of volatile metabolites released specifically by Staphylococcus aureus and Pseudomonas aeruginosa. |
| PubMed: | Different families of volatile organic compounds pollution control by microporous carbons in temperature swing adsorption processes. |
| PubMed: | Crucial aspects of high performance thin layer chromatography quantitative validation. The case of determination of rosmarinic acid in different matrices. |
| PubMed: | Reactions of the terminal Ni(II)-OH group in substitution and electrophilic reactions with carbon dioxide and other substrates: structural definition of binding modes in an intramolecular Ni(II)...Fe(II) bridged site. |
| PubMed: | Synthesis and electrophilic substitutions of novel pyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidines. |
| PubMed: | Chirped pulse Fourier transform microwave study of 2,2,2-trifluoroethyl formate. |
| PubMed: | A remarkable multicomponent cascade sequence for the formation of a spirocyclic polyether. |
| PubMed: | Another paradigm in solvent extraction-based microencapsulation technologies. |
| PubMed: | 1,3-Dihy-droxy-2-(hy-droxy-meth-yl)propan-2-aminium formate. |
| PubMed: | Strigolactone analogs derived from ketones using a working model for germination stimulants as a blueprint. |
| PubMed: | Fuel-specific influences on the composition of reaction intermediates in premixed flames of three C5H10O2 ester isomers. |
| PubMed: | Selective determination of aloin in different matrices by HPTLC densitometry in fluorescence mode. |
| PubMed: | Selected ion flow tube-mass spectrometry for absolute quantification of aroma compounds in the headspace of dry fermented sausages. |
| PubMed: | Determination of polyphenolics in extracts of Potentilla species by high-performance thin-layer chromatography photodensitometry method. |
| PubMed: | The atmospheric oxidation of diethyl ether: chemistry of the C2H5-O-CH(O.)CH3 radical between 218 and 335 K. |
| PubMed: | Toxicities of 31 volatile low molecular weight compounds against Aedes aegypti and Culex quinquefasciatus. |
| PubMed: | Modeling the heat and mass transfers in temperature-swing adsorption of volatile organic compounds onto activated carbons. |
| PubMed: | Analysis of formic acid in air samples. |
| PubMed: | Reverse micelle-based microencapsulation of oxytetracycline hydrochloride into poly-d,l-lactide-co-glycolide microspheres. |
| PubMed: | Gas-phase fragmentation study of novel synthetic 1,5-benzodiazepine derivatives using electrospray ionization tandem mass spectrometry. |
| PubMed: | Evidence for C-H...O=C bonding in coadsorbed aromatic-carbonyl systems on Pt(111). |
| PubMed: | Simultaneous determination of formic acid and formaldehyde in pharmaceutical excipients using headspace GC/MS. |
| PubMed: | Solvent effects on the structural and formyl substrate reactivity properties of a nitrogen/sulfur-ligated zinc hydroxide complex. |
| PubMed: | Cytochrome c oxidase inhibition in the rice weevil Sitophilus oryzae (L.) by formate, the toxic metabolite of volatile alkyl formates. |
| PubMed: | In vitro efficacy of plant volatiles for inhibiting the growth of fruit and vegetable decay microorganisms. |
| PubMed: | Synthesis of modified nucleosides for incorporation of formyletheno and carboxyetheno adducts of adenine nucleosides into oligonucleotides. |
| PubMed: | Degradation patterns of tetracycline antibiotics in reverse micelles and water. |
| PubMed: | Evaluation of volatile low molecular weight insecticides using Drosophila melanogaster as a model. |
| PubMed: | Characteristics of felodipine-located poly(epsilon-caprolactone) microspheres. |
| PubMed: | Surfactant-free microspheres of poly(epsilon-caprolactone)/poly (ethylene glycol)/poly(epsilon-caprolactone) triblock copolymers as a protein carrier. |
| PubMed: | Oxidative pyrolysis of organic ion exchange resins in the presence of metal oxide catalysts. |
| PubMed: | Determination of N-nitrosodiethanolamine in urine by gas chromatography thermal energy analysis: application in workers exposed to aqueous metalworking fluids. |
| PubMed: | Determination of alpha-bisabolol and d-panthenol in cosmetic products by gas chromatography. |
| PubMed: | Access to fluorescent probes via allyl glycosides: the synthesis of a Brucella trisaccharide epitope linked to a coumarin. |
| PubMed: | Synthesis of certain 2-aminoadamantane derivatives as potential antimicrobial agents. |
| PubMed: | Acetone, methyl ethyl ketone, ethyl acetate, acetonitrile and other polar aprotic solvents are strong inducers of aneuploidy in Saccharomyces cerevisiae. |
| PubMed: | Absorption dynamics of organic chemical transport across trout gills as related to octanol-water partition coefficient. |
| PubMed: | [Quality standard for Xindi soft capsule]. |
| PubMed: | From chemosensory thresholds to whole body exposures-experimental approaches evaluating chemosensory effects of chemicals. |
| PubMed: | Development of new reverse micellar microencapsulation technique to load water-soluble drug into PLGA microspheres. |
| PubMed: | Flexible synthesis of enantiomerically pure 2,8-dialkyl-1,7-dioxaspiro[5.5]undecanes and 2,7-dialkyl-1,6-dioxaspiro[4.5]decanes from propargylic and homopropargylic alcohols. |
| PubMed: | Ortho-Directed Lithiation of omega-Phenoxy Alcohols. |
| PubMed: | Cooperative reactivity of early-late heterodinuclear transition metal complexes with polar organic substrates |
| PubMed: | The synthesis of antibody binding-site probes: a hexasaccharide and two pentasaccharides related to the Brucella A antigen and prepared by in situ activation of thioglycosides with bromine. |
| PubMed: | The design and synthesis of antibody binding site probes: three pentasaccharide analogues of the Brucella A antigen prepared by activation in situ of thioglycosides with bromine. |
| PubMed: | 1,2-Dihydro-2-oxo-6-(2,2-dimethylpropyl)-3-pyridinecarboxylic acid, analogues, and derivatives. A new class of oral hypoglycemic agents. |
| PubMed: | Synthesis and pharmacological activity of derivatives of exo-trimethylenenorbornane. II. |
| PubMed: | [Steroidal heterocyclic compounds: [16,15-c]-pyrazole derivatives of estradiol and of estrone]. |
| PubMed: | Characterization of esterases produced by a ruminal bacterium identified as Butyrivibrio fibrisolvens. |
| PubMed: | Partial biochemical characterization of the activated esterase required in the complement-dependent chemotaxis of rabbit polymorphonuclear leukocytes. |
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