Articles:
2-methoxy-(3,5 or 6)-isopropylpyrazine
Notes:
Used as a food additive [EAFUS]
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 93905-03-4 2-Methoxy-3-isopropyl pyrazine
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Jiangyin Healthway International Trade Co., Ltd Independent Ingredients Supplier We provide custom synthesis and contract manufacturing from milligrams to metric tonnes. Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals. Email: Info Email: Sales Voice: 86-510-86023169 Fax: 86-510-86023170 Mobile 0086-13093133011 Services Biochemical Natural Food Colour New functional food ingredients Product(s): HL0127 2-Methoxy-3,5(6)-isopropyl pyrazine
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Pell Wall Perfumes Hand-made fragrances Pell Wall maintains a broad palette of ingredients & in order to keep stocks fresh & the options wide we also sell from our own stock. Pell Wall was founded by perfumer Chris Bartlett to provide exclusive hand-made fragrances to a select few people who love them. All our products are created using fine quality ingredients, many of which we also offer for sale to other perfumers and enthusiasts. Pell Wall make fragrances for men, for women and for the home. Email: Info Email: Sales Voice: +44 (0) 20 3745 0887 Facebook Twitter Instagram Blog Product(s): Green Pea Pyrazine Besides peppers and beans, this pyrazine, which consists of a mixture of isomers, occurs naturally in potatoes and a number of other vegetables and also has a raw-potato, earthy quality. Even at 0.1% this is a very powerful material that can easily dominate your blend, so use with caution in any blend where an original green-note is desired, or to add realism to galbanum, tomato and other green or fruity accords.
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 09-55150 ISOPROPYL METHOXY PYRAZINE
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Sigma-Aldrich Complete Supply Chain The perfect blend of products and services that bring your creativity to life. Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards. Email: Information US Email: Sales US Voice: 800-244-1173 US Fax: 800-368-4661 Facebook Twitter Instagram Linkedin Flavors and Fragrances Analysis FandF Newsletter Subscription Flavors and Fragrances Learning Center Certified Food Grade Products Product(s): W335809 2-Methoxy-3(5 or 6)-isopropylpyrazine, ≥98%, FG SDS
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| CAS Number: | 93905-03-4 |  3D/inchi
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| ECHA EINECS - REACH Pre-Reg: | 299-837-4 | |
| FDA UNII: | C90S36R5GY | |
| MDL: | MFCD00053106 | |
| CoE Number: | 11344 | |
| XlogP3: | 2.00 (est) | |
| Molecular Weight: | 456.59052000 | |
| Formula: | C24 H36 N6 O3 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| Also(can) Contains: | bean pyrazine | |
| EFSA/JECFA Comments: | Mixture of positional isomers (2-Isopropyl-3/5/6-methoxy), 2-3- (75-85 %); 2-5- (15-25 %) and 2-6-isomers (1-2 %) (sum 97 %) (EFFA, 2010a). | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 790 2-methoxy-(3,5 or 6)-isopropylpyrazine |
| DG SANTE Food Flavourings: | 14.121 2-isopropyl-(3,5 or 6)-methoxypyrazine |
| FEMA Number: | 3358 2-methoxy-(3,5 or 6)-isopropylpyrazine |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 93905-03-4 ; 2-METHOXY-(3 OR 5 OR 6)-ISOPROPYLPYRAZINE |
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 97.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.99600 @ 25.00 °C. |
| Boiling Point: | 205.00 to 207.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.360000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 152.00 °F. TCC ( 66.67 °C. ) |
| logP (o/w): | 2.160 (est) |
| Soluble in: | |
| alcohol | |
| water, 698.6 mg/L @ 25 °C (est) | |
| Stability: | |
| stable in most media | |
Organoleptic Properties:
| Odor Type: earthy | |
| earthy pepper bell pepper potato raw potato galbanum pea green pea | |
| Odor Description: at 0.10 % in dipropylene glycol. | earthy bell pepper raw potato galbanum |
| Odor and/or flavor descriptions from others (if found). | |
| Pell Wall Perfumes | |
| Green Pea Pyrazine | |
| Odor Description: | Bell-pepper, earthy, green-pea, raw potato Besides peppers and beans, this pyrazine, which consists of a mixture of isomers, occurs naturally in potatoes and a number of other vegetables and also has a raw-potato, earthy quality. Even at 0.1% this is a very powerful material that can easily dominate your blend, so use with caution in any blend where an original green-note is desired, or to add realism to galbanum, tomato and other green or fruity accords. |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| 2-Methoxy-3-isopropyl pyrazine |
| Jiangyin Healthway |
| 2-Methoxy-3,5(6)-isopropyl pyrazine |
| New functional food ingredients |
| Pell Wall Perfumes |
| Green Pea Pyrazine
Odor: Bell-pepper, earthy, green-pea, raw potato Use: Besides peppers and beans, this pyrazine, which consists of a mixture of isomers, occurs naturally in potatoes and a number of other vegetables and also has a raw-potato, earthy quality. Even at 0.1% this is a very powerful material that can easily dominate your blend, so use with caution in any blend where an original green-note is desired, or to add realism to galbanum, tomato and other green or fruity accords. |
| Penta International |
| ISOPROPYL METHOXY PYRAZINE |
| Sigma-Aldrich |
| 2-Methoxy-3(5 or 6)-isopropylpyrazine, ≥98%, FG |
| Certified Food Grade Products |
| Tengzhou Jitian Aroma Chemiclal |
| 2-Methoxy -3(5/6) - isopropyl pyrazine |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
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R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
gavage-rat LD50 880 mg/kg (Moran et al., 1980) | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for green pea pyrazine usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.0012 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.10 (μg/capita/day) | ||
| Structure Class: | II | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 6. Update in publication number(s): 29 | |||
| Click here to view publication 6 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | - | |
| beverages(nonalcoholic): | - | - | |
| beverages(alcoholic): | 0.00100 | 0.01000 | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | 0.05000 | 0.20000 | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | 0.05000 | 0.05000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | - | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | 0.20000 | 0.20000 | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf | |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf | |
| Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1] View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010) View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 71311442 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 2-methoxy-3-propan-2-ylpyrazine;2-methoxy-5-propan-2-ylpyrazine;2-methoxy-6-propan-2-ylpyrazine | |
| Chemidplus: | 0093905034 |
References:
| 2-methoxy-3-propan-2-ylpyrazine;2-methoxy-5-propan-2-ylpyrazine;2-methoxy-6-propan-2-ylpyrazine | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 71311442 |
| Pubchem (sid): | 162244287 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | HMDB32381 |
| FooDB: | FDB009800 |
| Export Tariff Code: | 2933.90.0000 |
| VCF-Online: | VCF Volatile Compounds in Food |
Potential Blenders and core components note
Potential Uses:
| earth | FR | |
| galbanum | FR | |
| krill | ||
| pepper bell pepper | FL | |
| potato | FL | |
| tomato | FL | |
| vegetable | FL |
Occurrence (nature, food, other): note
| pea green pea Search PMC Picture | |
| potato Search Trop Picture | |
| vegetables Search Picture |
Synonyms:
| 2- | methoxy-(3,5 or 6)-isopropylpyrazine |
| 2- | methoxy-3-propan-2-ylpyrazine;2-methoxy-5-propan-2-ylpyrazine;2-methoxy-6-propan-2-ylpyrazine |
| 2- | methoxy-3,5(6)-isopropyl pyrazine |
| 2- | methoxy-3(5 or 6)-isopropylpyrazine |
| iso | propyl methoxy pyrazine |
| iso | propyl methoxypyrazine |
| iso | propyl methylpyrazine |
| 2-iso | propyl-(3,5 or 6)-methoxypyrazine |
| 2-3,(5 or 6)-iso | propyl-2-methoxypyrazine |
| 2-iso | propyl-3,(5 or 6)-methoxypyrazine |
| 2-iso | propyl-3,5 or 6-methoxypyrazine |
| iso | propylmethoxypyrazine |