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Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 15.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 155.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 1.500000 mmHg @ 27.00 °C. (est) |
| Flash Point: | 147.00 °F. TCC ( 63.90 °C. ) (est)
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| logP (o/w): | 0.630 |
| Soluble in: |
| | alcohol |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: chocolate |
| |
| | nutty roasted potato baked potato |
Odor Description: at 0.10 % in dipropylene glycol. | nutty roasted baked potato |
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| Odor and/or flavor descriptions from others (if found). |
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| |
Cosmetic Information:
Suppliers:
| Advanced Biotech |
| 2 (5,6) DIMETHYL PYRAZINE
|
| Advanced Biotech |
| PYRAZINE MIXTURE IIII NATURAL
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| Advanced Biotech |
| PYRAZINE MIXTURE NATURAL
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| Anhui Suzhou Jinli Aromatic Chemicals |
| 2,5 or 6, 1-Dimethyl pyrazine
Odor: baked potato |
| Jinan Enlighten Chemical Technology(Wutong Aroma ) |
| 2,5(or6)-Dimethyl pyrazine, Kosherk
|
| M&U International |
| 2,5(OR6)-DIMETHYL PYRAZINE, Kosher
|
| Myrazine |
| 2,5-Dimethyl Pyrazine
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| Penta International |
| 2,5 + 2,6-DIMETHYL PYRAZINE MIXTURE NATURAL
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| Penta International |
| 2,5 + 2,6-DIMETHYL PYRAZINE MIXTURE
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| Reincke & Fichtner |
| Dimethyl Pyrazine natural
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| Synerzine |
| 2,5 & 2,6-DIMETHYL PYRAZINE MIXTURE, NATURAL
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| Synerzine |
| Mixture of 2,5-Dimeythlpyrazine and 2,6-Dimethylpyrazine
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| Synerzine |
| NATURAL DIMETHYL PYRAZINE MIXTURE (R&D PRODUCT)
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| Synerzine |
| Natural mixture of 2,5-dimeythlpyrazine and 2,6-dimethylpyrazine
|
| United International |
| 2,5(6)-Dimethyl Pyrazine Nat.
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| United International |
| 2,5(6)-Dimethyl Pyrazine
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| WholeChem |
| 2,5 & 2,6-Dimethylpyrazines Mixture
|
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 1350 mg/kg Toxicology and Applied Pharmacology. Vol. 17, Pg. 244, 1970.
oral-rat LD50 1020 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.
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| Dermal Toxicity: |
|
Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | flavoring agents |
| Recommendation for 2,5-dimethyl pyrazine and 2,6-dimethyl pyrazine mixture usage levels up to: | | | not for fragrance use.
|
| |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 5 |
| Click here to view publication 5 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 10.00000 |
| beverages(nonalcoholic): | - | 10.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | 10.00000 |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 10.00000 |
| fruit ices: | - | 10.00000 |
| gelatins / puddings: | - | 10.00000 |
| granulated sugar: | - | - |
| gravies: | - | 10.00000 |
| hard candy: | - | 10.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 10.00000 |
| milk products: | - | 10.00000 |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | 10.00000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): |
| The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 123-32-0 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 31252 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | 2,5-dimethylpyrazine |
| Chemidplus: | 0000123320 |
| RTECS: | UQ2800000 for cas# 123-32-0 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| caramellic |
| caramellic |
| iso | propenyl pyrazine | FL/FR |
| chocolate |
| 2,5- | dimethyl pyrazine | FL/FR |
| green |
| 2-tert- | butyl pyrazine | FL/FR |
| 2- | heptyl furan | FL/FR |
| 2- | acetyl-3-methyl pyrazine | FL/FR |
| 2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| 3,6- | cocoa pyrazine | FL/FR |
| | filbert heptenone B | FL/FR |
| | methoxymethyl pyrazine | FL/FR |
| | nutty quinoxaline | FL/FR |
| | sesame absolute | FL/FR |
| roasted |
| 2- | acetyl-2-pyrroline | |
| |
| For Flavor |
| |
| No flavor group found for these |
| 2- | acetyl-2-pyrroline | |
| 2-tert- | butyl pyrazine | FL/FR |
| 6,7- | dimethyl dihydrocyclopentapyrazine | FL |
| | methyl 2-(methyl thio) acetate | FL |
| | pyrazines mixture | FL |
|
| 5- | acetyl-2,3-dihydro-1,4-thiazine | FL |
| burnt |
| iso | propenyl pyrazine | FL/FR |
| fatty |
| 2- | heptyl furan | FL/FR |
| fishy |
| 4,5- | dimethyl thiazole | FL |
| fruity |
| 2- | ethyl-2,5-dihydro-4-methyl thiazole | FL |
| musty |
| 2,5- | dimethyl pyrazine | FL/FR |
| 2- | ethoxythiazole | FL |
| nutty |
| 3- | acetyl-2,5-dimethyl thiophene | FL |
| 2- | acetyl-3-methyl pyrazine | FL/FR |
| 2- | acetyl-3,5-dimethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| | arachis hypogaea fruit extract | FL |
| 3,6- | cocoa pyrazine | FL/FR |
| 1- | ethyl-2-acetyl pyrrole | FL |
| 2- | ethyl-6-methyl pyrazine | FL |
| | filbert heptenone B | FL/FR |
| | methoxymethyl pyrazine | FL/FR |
| | nutty quinoxaline | FL/FR |
| | sesame absolute | FL/FR |
| roasted |
| 3,5- | diisobutyl-1,2,4-trithiolane | FL |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2 (5,6)- | dimethyl pyrazine | | 2,6- | dimethyl pyrazine and 2,5-dimethyl pyrazine mixture | | 2,5 & 2,6- | dimethyl pyrazine mixture | | 2,5 & 2,6- | dimethyl pyrazine mixture natural | | 2,5- | dimethylpyrazine (contains 2,6-isomer) | | 2,6- | dimethylpyrazine and 2,5-dimethylpyrazine mixture | | 2,5- | dimethylpyrazine and 2,6-dimethylpyrazine | | 2,5- | dimethylpyrazine and 2,6-dimethylpyrazine mixture | | 2,5(2,6)- | dimethylpyrazine mixture |
Articles:
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