2,5-dimethyl pyrazine and 2,6-dimethyl pyrazine mixture
2,5-dimethylpyrazine and 2,6-dimethylpyrazine mixture
 
Notes:
Used as flavour additive and odorant in foods. Present in asparagus, wheat bread, crispbread, Swiss cheeses, black or green tea, soya, malt, raw shrimp and squid
  • Advanced Biotech
    • Advanced Biotech. Inc.
      Inspired by Nature
      A diverse range of products, all meeting our stringent commitment to quality.
      Advanced Biotech is a leading manufacturer and supplier of high-quality Natural flavoring ingredients & botanical extracts for the food/beverage, cosmetic and personal care industries. With over 25 years of experience working with Fermentation processing & botanical extracts, we can help develop new innovative and functional products for today‪s competitive marketplace. Our company prides itself in the ability to cater to our customer‪s specific needs while maintaining our focus on integrity, honesty and the commitment to high quality product standards. We proudly offer our quality Natural ingredients to companies around the world.
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      Product(s):
      4076 2 (5,6) DIMETHYL PYRAZINE
      SDS
      1489 PYRAZINE MIXTURE IIII NATURAL
      SDS
      1345 PYRAZINE MIXTURE NATURAL
      SDS
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
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      Product(s):
      H0199 2,5(OR6)-DIMETHYL PYRAZINE, Kosher
       
  • Myrazine
    • Myrazine LLC
      EU Natural Ingredients from Fermentation
      All the materials are sourced from fermentation.
      Myrazine LLC,formerly known as Cheng Smith LLC, and Abioco, started its search for Natural materials in 2000, when we started to import natural alcohols from China. China's liquor fermentation technology is as old as the country. Chinese liquor is? unique, because it is fermented from grains, such as rice, wheat, sorghum, and barleys. With bacteria or microorganism present in the fermentaiton, Chinese liquor is rich in flavours. It is reported that there are over 100 flavour materials in the liquor fermentation broth. During the production, the "good" liquor is distilled out, and the "bad" alcohols are dumped as "wastes" before 1980s. Fusel oil is regarded and dumped as the "bad" one during the production. Today, every single ton of the liquor fermentation "wastes" --- fusel oil, has been physically distilled. Alcohols from these distillations are methyl alcohol, ethanol, propanol, butanol, iso-butanol, iso-amyl alcohol, etc. Most of the alcohols are used by the flavour and fragrances industry as raw materials, which eventually go into the beverages, food, and some daily products. According to the US and EU regulations about natural ingredients, materials from fermentation are regarded as "natural".
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      Product(s):
      2,5-Dimethyl Pyrazine
       
  • Penta International
  • Synerzine
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
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      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
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      Product(s):
      10045 2,5(6)-Dimethyl Pyrazine
      10045N 2,5(6)-Dimethyl Pyrazine Nat.
       
  • WholeChem
    • WholeChem, LLC
      Connecting Innovators To the Building Blocks Of the Universe
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      Product(s):
      2,5 & 2,6-Dimethylpyrazines Mixture
       
Synonyms   Articles   Notes   Search
CAS Number: 123-32-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 204-618-3
FDA UNII: V99Y0MUY1Q
Nikkaji Web: J2.009E
Beilstein Number: 0107052
MDL: MFCD00006147
CoE Number: 2210
XlogP3: 0.60 (est)
Molecular Weight: 108.14376000
Formula: C6 H8 N2
NMR Predictor: Predict (works with chrome, Edge or firefox)
Also(can) Contains: 2,6-dimethyl pyrazine
EFSA/JECFA Comments: Mixture of positional isomers (2,5- and 2,6-isomers), 2,5- (45-65 %) and 2,6-isomers (35-55 %) (sum 98 %) (EFFA, 2010a).
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 766  2,5-dimethylpyrazine
FEMA Number: 3272 2,5-dimethylpyrazine and 2,6-dimethylpyrazine mixture
FDA:No longer provide for the use of these seven synthetic flavoring substances
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 15.00 °C. @ 760.00 mm Hg
Boiling Point: 155.00 °C. @ 760.00 mm Hg
Vapor Pressure: 1.500000 mmHg @ 27.00 °C. (est)
Flash Point: 147.00 °F. TCC ( 63.90 °C. ) (est)
logP (o/w): 0.630
Soluble in:
 alcohol
Insoluble in:
 water
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Organoleptic Properties:
 
Odor Type: chocolate
 
 nutty  roasted  potato baked potato  
Odor Description:
at 0.10 % in dipropylene glycol. 
nutty roasted baked potato
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Advanced Biotech
2 (5,6) DIMETHYL PYRAZINE
Advanced Biotech
PYRAZINE MIXTURE IIII NATURAL
Advanced Biotech
PYRAZINE MIXTURE NATURAL
Anhui Suzhou Jinli Aromatic Chemicals
2,5 or 6, 1-Dimethyl pyrazine
Odor: baked potato
Jinan Enlighten Chemical Technology(Wutong Aroma )
2,5(or6)-Dimethyl pyrazine, Kosherk
M&U International
2,5(OR6)-DIMETHYL PYRAZINE, Kosher
Myrazine
2,5-Dimethyl Pyrazine
Penta International
2,5 + 2,6-DIMETHYL PYRAZINE MIXTURE NATURAL
Penta International
2,5 + 2,6-DIMETHYL PYRAZINE MIXTURE
Reincke & Fichtner
Dimethyl Pyrazine natural
Synerzine
2,5 & 2,6-DIMETHYL PYRAZINE MIXTURE, NATURAL
Synerzine
Mixture of 2,5-Dimeythlpyrazine and 2,6-Dimethylpyrazine
Synerzine
NATURAL DIMETHYL PYRAZINE MIXTURE (R&D PRODUCT)
Synerzine
Natural mixture of 2,5-dimeythlpyrazine and 2,6-dimethylpyrazine
United International
2,5(6)-Dimethyl Pyrazine Nat.
United International
2,5(6)-Dimethyl Pyrazine
WholeChem
2,5 & 2,6-Dimethylpyrazines Mixture
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  1350 mg/kg
Toxicology and Applied Pharmacology. Vol. 17, Pg. 244, 1970.

oral-rat LD50  1020 mg/kg
Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavoring agents
Recommendation for 2,5-dimethyl pyrazine and 2,6-dimethyl pyrazine mixture usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5
Click here to view publication 5
 average usual ppmaverage maximum ppm
baked goods: -10.00000
beverages(nonalcoholic): -10.00000
beverages(alcoholic): --
breakfast cereal: -10.00000
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -10.00000
fruit ices: -10.00000
gelatins / puddings: -10.00000
granulated sugar: --
gravies: -10.00000
hard candy: -10.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: -10.00000
milk products: -10.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: -10.00000
sugar substitutes: --
sweet sauces: --
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Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 123-32-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 31252
National Institute of Allergy and Infectious Diseases: Data
 2,5-dimethylpyrazine
Chemidplus: 0000123320
RTECS: UQ2800000 for cas# 123-32-0
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References:
 2,5-dimethylpyrazine
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 123-32-0
Pubchem (cid): 31252
Pubchem (sid): 134974393
Flavornet: 123-32-0
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): HMDB35289
FooDB: FDB013954
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
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Potential Blenders and core components note
 
For Odor
caramellic
caramellic
isopropenyl pyrazineFL/FR
chocolate
2,5-dimethyl pyrazineFL/FR
green
2-tert-butyl pyrazineFL/FR
2-heptyl furanFL/FR
2-acetyl-3-methyl pyrazineFL/FR
2-acetyl-3,5-dimethyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
3,6-cocoa pyrazineFL/FR
 filbert heptenone BFL/FR
 methoxymethyl pyrazineFL/FR
 nutty quinoxalineFL/FR
 sesame absoluteFL/FR
roasted
2-acetyl-2-pyrroline 
 
For Flavor
 
No flavor group found for these
2-acetyl-2-pyrroline 
2-tert-butyl pyrazineFL/FR
6,7-dimethyl dihydrocyclopentapyrazineFL
 methyl 2-(methyl thio) acetateFL
 pyrazines mixtureFL
5-acetyl-2,3-dihydro-1,4-thiazineFL
burnt
isopropenyl pyrazineFL/FR
fatty
2-heptyl furanFL/FR
fishy
4,5-dimethyl thiazoleFL
fruity
2-ethyl-2,5-dihydro-4-methyl thiazoleFL
musty
2,5-dimethyl pyrazineFL/FR
2-ethoxythiazoleFL
nutty
3-acetyl-2,5-dimethyl thiopheneFL
2-acetyl-3-methyl pyrazineFL/FR
2-acetyl-3,5-dimethyl pyrazineFL/FR
2-acetyl-3,5(or 6)-dimethyl pyrazineFL/FR
 arachis hypogaea fruit extractFL
3,6-cocoa pyrazineFL/FR
1-ethyl-2-acetyl pyrroleFL
2-ethyl-6-methyl pyrazineFL
 filbert heptenone BFL/FR
 methoxymethyl pyrazineFL/FR
 nutty quinoxalineFL/FR
 sesame absoluteFL/FR
roasted
3,5-diisobutyl-1,2,4-trithiolaneFL
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 can be natural
 fenugreek seed
Search Trop  Picture
 garlic bulb
Search Trop  Picture
 kohlrabi stem
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Synonyms:
2 (5,6)-dimethyl pyrazine
2,6-dimethyl pyrazine and 2,5-dimethyl pyrazine mixture
2,5 & 2,6-dimethyl pyrazine mixture
2,5 & 2,6-dimethyl pyrazine mixture natural
2,5-dimethylpyrazine (contains 2,6-isomer)
2,6-dimethylpyrazine and 2,5-dimethylpyrazine mixture
2,5-dimethylpyrazine and 2,6-dimethylpyrazine
2,5-dimethylpyrazine and 2,6-dimethylpyrazine mixture
2,5(2,6)-dimethylpyrazine mixture
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