Articles:
| PubMed: | Reactions of cobalt carbene complexes with alkynes. .eta.4-Vinylketene-complexed intermediates and a novel synthesis of bovolide. |
4-hydroxy-2,3-dimethyl-2,4-nonadienoic acid gamma-lactone
Notes:
Constit. of peppermint oil
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 774-64-1 2(5H)-Furanone, 3,4-dimethyl-5-pentylidene-, (5Z)- 95%
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Soda Aromatic Co., Ltd. Depth of Experience We guarantees product safety and quality. Our international sales department is happy to design the most suitable flavor & fragrance for specific uses of processed food, cosmetics, and fragrance manufactures all over the world, specializing in Asia.Let us help you with your flavor & fragrance needs. Email: Info Email: Sales Voice: +81-3-5645-7347 Fax: +81-3-3664-5204 Product(s): 110224025 Bovolide
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| CAS Number: | 774-64-1 |  3D/inchi
|
| Nikkaji Web: | J3.124.569I | |
| Beilstein Number: | 1343514 | |
| CoE Number: | 11873 | |
| XlogP3: | 2.90 (est) | |
| Molecular Weight: | 180.24692000 | |
| Formula: | C11 H16 O2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | At least 93%; secondary component 1-2% 3,4-dimethyl 5-ketobutanoic acid gamma-lactone. (EFSA) | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 2002 4-hydroxy-2,3-dimethyl-2,4-nonadienoic acid gamma-lactone |
| DG SANTE Food Flavourings: | 10.042 3,4-dimethyl-5-pentylidenefuran-2(5H)-one |
| FEMA Number: | 4050 4-hydroxy-2,3-dimethyl-2,4-nonadienoic acid gamma-lactone |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 774-64-1 ; 4-HYDROXY-2,3-DIMETHYL-2,4-NONADIENOIC ACID GAMMA LACTONE |
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 93.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.93000 to 0.98000 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 7.739 to 8.155 |
| Refractive Index: | 1.56000 to 1.57500 @ 20.00 °C. |
| Boiling Point: | 302.00 to 303.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.002000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 244.00 °F. TCC ( 117.78 °C. ) |
| logP (o/w): | 2.029 (est) |
| Soluble in: | |
| alcohol | |
| water | |
| water, 194.2 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor Type: spicy | |
| spicy herbal minty | |
| Odor Description: at 100.00 %. | spicy herbal minty |
| Flavor Type: buttery | |
| buttery | |
| Taste Description: | buttery |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| 2(5H)-Furanone, 3,4-dimethyl-5-pentylidene-, (5Z)- 95% |
| Parchem |
| bovolide |
| Soda Aromatic |
| Bovolide |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for bovolide usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.01 (μg/capita/day) | ||
| Structure Class: | III | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 21 | |||
| Click here to view publication 21 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 3.00000 | 6.00000 | |
| beverages(nonalcoholic): | 1.00000 | 2.00000 | |
| beverages(alcoholic): | 1.00000 | 2.00000 | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | 5.00000 | 10.00000 | |
| condiments / relishes: | 1.00000 | 2.00000 | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | 2.00000 | 4.00000 | |
| fruit ices: | 1.00000 | 2.00000 | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | 1.00000 | 2.00000 | |
| hard candy: | 2.00000 | 4.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | 1.00000 | 2.00000 | |
| milk products: | 1.00000 | 2.00000 | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | 1.00000 | 2.00000 | |
| soft candy: | 2.00000 | 4.00000 | |
| soups: | 1.00000 | 2.00000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| List of apha, beta-Unsaturated Aldehydes and Ketones representative of FGE.19 substances for Genotoxicity Testing [1] - Statement of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf | |
| Flavouring Group Evaluation 217: alpha,beta-Unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones[1] View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 217 Revision 2 (FGE.217Rev2), consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 6433214 |
| National Institute of Allergy and Infectious Diseases: | Data |
| (5E)-3,4-dimethyl-5-pentylidenefuran-2-one | |
| Chemidplus: | 0000774641 |
References:
| (5E)-3,4-dimethyl-5-pentylidenefuran-2-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 774-64-1 |
| Pubchem (cid): | 6433214 |
| Pubchem (sid): | 134978557 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB39159 |
| FooDB: | FDB018683 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
| FAO: | 4-Hydroxy-2,3-dimethyl-2,4-nonadienoic acid gamma-lactone |
Potential Blenders and core components note
Potential Uses:
| butter | FL |
Occurrence (nature, food, other): note
| beef Search PMC Picture | |
| champaca concrete @ 0.01% Data GC Search Trop Picture | |
| nepeta betonicifolia c.a. meyer oil turkey @ 0.30% Data GC Search Trop Picture | |
| peppermint leaf Search Trop Picture | |
| peppermint oil Search Trop Picture | |
| soybean Search Trop Picture | |
| tea Search Trop Picture |
Synonyms:
| 3,4- | dimethyl-5-pentylidene furan-2(5H)-one |
| 3,4- | dimethyl-5-pentylidene-2(5H)-furanone |
| (5E)-3,4- | dimethyl-5-pentylidenefuran-2-one |
| 3,4- | dimethyl-5-pentylidenefuran-2(5H)-one |
| 2(5H)- | furanone, 3,4-dimethyl-5-pentylidene- |
| 4- | hydroxy-2,3-dimethyl-2,4-nonadienoic acid gamma-lactone |
| 5- | pentylidene-3,4-dimethyl-2,5-dihydrofuran-2-one |