|
Category: cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | pale yellow to dark yellow clear oily liquid (est) |
| Assay: | 97.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.94000 to 0.95600 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 7.822 to 7.955
|
| Refractive Index: | 1.50400 to 1.51300 @ 20.00 °C.
|
| Optical Rotation: | -125.00 to -118.00
|
| Boiling Point: | 238.00 to 240.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 0.043000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 200.00 °F. TCC ( 93.33 °C. )
|
| logP (o/w): | 3.053 (est) |
| Soluble in: |
| | alcohol | | | oils | | | water, 160.7 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: herbal |
| |
| Odor Strength: | high , recommend smelling in a 10.00 % solution or less |
| |
| Substantivity: | 8 hour(s) at 100.00 % |
| |
| | fresh green herbal grassy sweet minty cumin |
Odor Description: at 10.00 % in dipropylene glycol. | fresh green herbal grassy sweet mint cumin Luebke, William tgsc, (1986) |
| |
| | spicy cumin cinnamon pungent clove citrus orange lime |
Odor Description:
| Spicy, cumin, cinnamon, pungent, clove, citrus, orange and lime Mosciano, Gerard P&F 22, No. 5, 67, (1997) |
| |
| |
| Flavor Type: spicy |
| |
| | woody spicy waxy sweet citrus lime aldehydic |
Taste Description: at 25.00 ppm. | Woody, spicy, waxy, sweet, citrus, lime and aldehydic Mosciano, Gerard P&F 22, No. 5, 67, (1997) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 1720 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 799, 1982.
|
| Dermal Toxicity: |
skin-guinea pig LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 799, 1982.
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | cosmetic, flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| IFRA Critical Effect: | Dermal sensitization |
| IFRA fragrance material specification: | | | Should not be used such that the level in finished cosmetic products
exceeds 0.1%. Based on test results showing sensitisation (IFRA
guidelines). |
| IFRA: | View Standard |
| View IFRA Standards Library for complete information. |
| Please review Amendment 49 IFRA documentation for complete information. |
| IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): |
| Category 1: Products applied to the lips |
| 0.054 % |
| Category 2: Products applied to the axillae |
| 0.016 % |
| Category 3: Products applied to the face/body using fingertips |
| 0.32 % |
| Category 4: Products related to fine fragrance |
| 0.30 % |
| | Category 5: Products applied to the face and body using the hands (palms), primarily leave-on |
| Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on |
| 0.076 % |
| Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on |
| 0.076 % |
| Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on |
| 0.076 % |
| Category 5D: Baby Creams, baby Oils and baby talc |
| 0.076 % |
| Category 6: Products with oral and lip exposure |
| 0.18 % |
| | Category 7: Products applied to the hair with some hand contact |
| Category 7A: Rinse-off products applied to the hair with some hand contact |
| 0.61 % |
| Category 7B: Leave-on products applied to the hair with some hand contact |
| 0.61 % |
| Category 8: Products with significant anogenital exposure |
| 0.032 % |
| Category 9: Products with body and hand exposure, primarily rinse off |
| 0.59 % |
| | Category 10: Household care products with mostly hand contact |
| Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) |
| 2.10 % |
| Category 10B: Household aerosol/spray products |
| 2.10 % |
| | Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate |
| Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure |
| 1.20 % |
| Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure |
| 1.20 % |
| Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin |
| No Restriction |
| | Notes: |
| IFRA FLAVOR REQUIREMENTS: |
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. |
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 2.10 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 2.00 (μg/capita/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 11 |
| Click here to view publication 11 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 4.50000 |
| beverages(nonalcoholic): | - | 4.00000 |
| beverages(alcoholic): | - | 6.00000 |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 6.30000 |
| fruit ices: | - | - |
| gelatins / puddings: | - | 4.50000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | 20.00000 |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | 9.70000 |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): |
| The FEMA GRAS assessment of alicyclic substances used as flavor ingredients. View pdf |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
List of apha, beta-Unsaturated Aldehydes and Ketones representative of FGE.19 substances for Genotoxicity Testing [1] - Statement of the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 208 Revision 1 (FGE.208Rev1): Consideration of genotoxicity data on representatives for 10 alicyclic aldehydes with the a,ß-unsaturation in ring / side-chain and precursors from chemical subgroup 2.2 of View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 208 Revision 2 (FGE.208Rev2): Consideration of genotoxicity data on alicyclic aldehydes with a,ß-unsaturation in ring/side-chain and precursors from chemical subgroup 2.2 of FGE.19 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 208 Revision 2 (FGE.208Rev2): Consideration of genotoxicity data on alicyclic aldehydes with a,ß-unsaturation in ring/side-chain and precursors from chemical subgroup 2.2 of FGE.19 View page or View pdf |
Scientific Opinion on Flavouring Group Evaluation 208 Revision 3 (FGE.208Rev3): consideration of genotoxicity data on alicyclic aldehydes with a,ß-unsaturation in ring/side-chain and precursors from chemical subgroup 2.2 of FGE.19 View page or View pdf |
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 2111-75-3 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 16441 |
| National Institute of Allergy and Infectious Diseases: | Data |
| SCCNFP: | opinion |
| WGK Germany: | 3 |
| | 4-prop-1-en-2-ylcyclohexene-1-carbaldehyde |
| Chemidplus: | 0002111753 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| No odor group found for these |
| | tagete oil rwanda | |
| aldehydic |
| | agrumen nitrile | FR |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| | fresh carbaldehyde | FR |
| | undecanal | FL/FR |
| alliaceous |
| | dibutyl sulfide | FL/FR |
| animal |
| iso | butyl quinoline | FR |
| | methyl (E)-2-octenoate | FL/FR |
| anisic |
| | estragole | FL/FR |
| | ocimum basilicum leaf oil america | FL/FR |
| balsamic |
| | cinnamyl formate | FL/FR |
| | guaiyl acetate | FL/FR |
| christmas | pine fragrance | FR |
| camphoreous |
| 2,6- | dimethyl-3-oxatricyclo(4.2.1.0*2,4*)nonane | FR |
| caramellic |
| 2-iso | butyl-3-methyl pyrazine | FL/FR |
| cheesy |
| iso | valeric acid | FL/FR |
| chocolate |
| iso | butyl phenyl acetate | FL/FR |
| | cocoa pentenal | FL/FR |
| citrus |
| iso | decyl acetate | FR |
| | lime pyran | FR |
| | litsea cubeba fruit oil | FL/FR |
| | melissa absolute replacer | FL/FR |
| | melissa oil replacer | FR |
| | ocimene quintoxide | FL/FR |
| | verbena absolute france | FL/FR |
| earthy |
| | geosmin | FL/FR |
| (S)-1- | octen-3-ol | FL/FR |
| ethereal |
| | ethyl 4-pentenoate | FL/FR |
| 3- | decen-2-one | FL/FR |
| | methyl 2-hexenoate | FL/FR |
| (E)-2- | nonenal | FL/FR |
| (E)-2- | octenal | FL/FR |
| 2- | octenal | FL/FR |
| (E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
| floral |
| | cassis oxime 10% | FR |
| | cilantro herb oil egypt | FL/FR |
| | cymbopogon validus leaf oil | FR |
| | dictamnus hispanicus oil | FR |
| | dihydrocitronellyl ethyl ether | FR |
| | dihydrorose oxide | FR |
| | dimethyl benzyl carbinyl butyrate | FL/FR |
| 2,4- | dimethyl-3-cyclohexene-1-methanol | FR |
| 4,6- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
| 2,4- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
| | geranium oil egypt | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | hydroxycitronellal | FL/FR |
| | linden flower absolute | FR |
| | melaleuca ericifolia leaf oil | FR |
| para- | methyl benzyl acetate | FL/FR |
| | mimosa absolute france | FL/FR |
| beta- | naphthyl methyl ketone | FL/FR |
| | neryl formate | FL/FR |
| 3- | nonanone | FL/FR |
| iso | phytol | FL/FR |
| | prenyl salicylate | FL/FR |
| | reseda absolute | FR |
| | rose butanoate | FL/FR |
| | rose pyran | FR |
| 5- | tricyclodecenyl acetate | FR |
| | ylang ylang flower oil I | FL/FR |
| fruity |
| 3- | butyl bicyclo[3.2.1]-6-octen-2-one | FR |
| | cinnamyl isobutyrate | FL/FR |
| | ethyl 2-ethyl acetoacetate | FL/FR |
| | ethyl hexanoate | FL/FR |
| 1- | ethyl-2-methyl propyl chrysanthemumate | |
| | methyl 2-methyl butyrate | FL/FR |
| 2- | methyl-2-pentenal | FL/FR |
| | octen-1-yl cyclopentanone | FL/FR |
| | tropical indene | FR |
| garlic |
| 4- | methyl-2-[2-(methyl thio)ethyl]-1,3-oxathiane | |
| green |
| | agrumen aldehyde | FR |
| | bark carbaldehyde | FR |
| | birch leaf specialty | FR |
| | butyl heptanoate | FL/FR |
| iso | butyl heptanoate | FL/FR |
| iso | butyl methyl ketone | FL/FR |
| S-sec- | butyl thioisovalerate | FL/FR |
| sec- | butyl-3-methyl but-2-ene thioate | FL/FR |
| | carrot leaf oil (daucus carota ssp.maximus) | FR |
| | chrysanthemum carbaldehyde | FR |
| 3,7- | dimethyl-6-octenoic acid | FL/FR |
| | dodecanal dimethyl acetal | FL/FR |
| | heptanal (aldehyde C-7) | FL/FR |
| | heptanal cyclic propylene acetal | FL/FR |
| 3- | heptanone | FL/FR |
| (Z)-3- | hepten-1-ol | FL/FR |
| 3- | hepten-2-one | FL/FR |
| (Z)-4- | heptenal | FL/FR |
| 2- | heptenal | FL/FR |
| | heptyl benzoate | FL/FR |
| 2- | heptyl furan | FL/FR |
| | heptyl heptanoate | FL/FR |
| | hexanal (aldehyde C-6) | FL/FR |
| | hexanal dihexyl acetal | FL/FR |
| (E)-4- | hexen-1-ol | |
| (Z)-3- | hexen-1-yl benzoate | FL/FR |
| (Z)-3- | hexenal | FL/FR |
| 3- | hexenyl 2-methyl butyrate | FL/FR |
| alpha- | hexyl cinnamaldehyde dimethyl acetal | FR |
| english | ivy leaf absolute | FR |
| | lilac acetaldehyde | FL/FR |
| | marigold pot absolute | FL/FR |
| 6- | methyl-3-hepten-2-one | FL/FR |
| (E,Z)-3,6- | nonadien-1-ol | FL/FR |
| (E,Z)-2,6- | nonadienal | FL/FR |
| (E)-2- | octen-1-yl acetate | FL/FR |
| 3- | propyl bicyclo(3.2.1)-6-octen-2-one | FR |
| | propylene acetal | FL/FR |
| | seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| | terpinyl propionate | FL/FR |
| 3,5,5- | trimethyl hexanol | FL/FR |
| | triplal / ethyl anthranilate schiff's base | FR |
| 9- | acetyl-5-methyl-tricyclo[6.2.1.0.sup.2,7 ]undec-4-ene | |
| | anethum graveolens herb oil | FL/FR |
| | anethum graveolens herb tincture | FL/FR |
| | anthemis nobilis flower extract | FL/FR |
| | anthemis nobilis flower oil roman | FL/FR |
| | apium graveolens seed oil | FL/FR |
| | apium graveolens seed oil india | FL/FR |
| | artemisia alba oil | FR |
| sweet | basil absolute | FL/FR |
| (+)-alpha- | campholenic aldehyde | FL/FR |
| | chrysanthemum ketone | FR |
| | coriander oleoresin | FL/FR |
| 2- | cyclohexyl cyclohexanone | FR |
| | dill weed oil cuba | FL/FR |
| | dill weed oil reunion | FL/FR |
| | dimethyl benzyl carbinyl formate | FL/FR |
| 2-(2,4- | dimethyl-3-cyclohexene-1-yl)-4,4-dimethyl-1,3-oxathiane | FR |
| sweet | grass fragrance | FR |
| cis- | herbal cyclohexane | FR |
| | herbal dioxane | FR |
| | herbal heptane | FR |
| | hop absolute | FL/FR |
| | hop oil | FL/FR |
| | lantana camara flower oil | FR |
| | levisticum officinale herb oil | FL/FR |
| | marigold oil mexico | FL/FR |
| | melaleuca leucadendron var. cajuputi leaf oil | FL/FR |
| 1-(2- | methyl allyl oxy) heptane | FR |
| (E)-6- | methyl-3-hepten-2-one | FL/FR |
| | mistletoe absolute | |
| | monarda fistulosa oil | FR |
| | myrtenol | FL/FR |
| | nonisyl formate | FR |
| (E,Z)-3,5- | octadien-2-one | |
| 1- | octen-3-yl acetate | FL/FR |
| | oregano specialty | FR |
| | origanum oil | FL/FR |
| | origanum oil greece | FL/FR |
| | perilla leaf oil | FL/FR |
| laevo- | perillaldehyde | FL/FR |
| | petroselinum crispum seed oil CO2 extract | FL/FR |
| | phenyl acetaldehyde diisoamyl acetal | FR |
| | prenyl senecioate | FL/FR |
| | rosmarinus officinalis extract | FL/FR |
| | rosmarinus officinalis tincture | FL/FR |
| | tagete oil CO2 extract | FL/FR |
| | theaspirane | FL/FR |
| | thyme absolute | FL/FR |
| | thymol | FL/FR |
| | tricyclodecyl acetate | FR |
| | viridiflorol | FL/FR |
| | wormwood oil america | FL/FR |
| | wormwood oil italy | FL/FR |
| | wormwood oil poland | FL/FR |
| honey |
| | methyl phenyl acetate | FL/FR |
| minty |
| (-)- | menthone | FL/FR |
| mossy |
| | treemoss absolute | FR |
| soapy |
| | methyl anthranilate / hexyl cinnamaldehyde schiff's base | FR |
| spicy |
| | allspice leaf oil | FL/FR |
| iso | butyl angelate | FL/FR |
| | cinnamon bark oil (cinnamomum zeylanicum) india | FL/FR |
| | cinnamon bark oil ceylon | FL/FR |
| | cinnamon oleoresin ceylon | FL/FR |
| | clove bud oil CO2 extract | FL/FR |
| | croton eluteria bark oil | FL/FR |
| | cuminaldehyde | FL/FR |
| 3-(2- | furyl) acrolein | FL/FR |
| | ginger root oil china | FL/FR |
| | gingergrass oil | FR |
| ortho- | methoxycinnamaldehyde | FL/FR |
| | methyl isoeugenol | FL/FR |
| | nutmeg oil | FL/FR |
| | origanum majorana oil | FL/FR |
| | outdoors specialty | FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| | pepper tree berry oil | FL/FR |
| | spicy carbonate | FR |
| alpha- | phellandrene | FL/FR |
| gamma- | terpinene | FL/FR |
| waxy |
| | ethyl myristate | FL/FR |
| | ethyl octanoate | FL/FR |
| 2,4- | nonadien-1-ol | FL/FR |
| 1- | undecanol | FL/FR |
| woody |
| | cinnamyl tiglate | FL/FR |
| | curcuma zedoaria bark extract | FL/FR |
| | dalbergia sissoo leaf oil | FR |
| alpha- | farnesene | FL/FR |
| alpha- | farnesene isomer | FL/FR |
| | guaiacyl acetate | FL/FR |
| | sabinene | FL/FR |
| alpha- | thujene | |
| | verdoxan | FR |
| | zedoary bark oil | FL/FR |
| | zedoary root oil | FL/FR |
| | zedoary root oil CO2 extract | FL/FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| 4- | acetyl-2-isopropenyl pyridine | FL |
| 9- | acetyl-5-methyl-tricyclo[6.2.1.0.sup.2,7 ]undec-4-ene | |
| iso | butyl heptanoate | FL/FR |
| 4- | butyl thiazole | FL |
| S-sec- | butyl thioisovalerate | FL/FR |
| sec- | butyl-3-methyl but-2-ene thioate | FL/FR |
| | cinnamyl tiglate | FL/FR |
| | dimethyl benzyl carbinyl formate | FL/FR |
| | epoxy-2-decenal | FL |
| | ethyl 4-pentenoate | FL/FR |
| 2- | ethyl pyridine | FL |
| 1- | ethyl-2-methyl propyl chrysanthemumate | |
| | fig leaf absolute | FL |
| | furfuryl hexanoate | FL |
| 3-(2- | furyl) acrolein | FL/FR |
| | guaiyl acetate | FL/FR |
| | heptanal cyclic propylene acetal | FL/FR |
| (Z)-3- | hepten-1-ol | FL/FR |
| 2- | heptenal | FL/FR |
| 2- | heptenoic acid | FL |
| | heptyl benzoate | FL/FR |
| (E,E)-2,4- | hexadien-1-ol | FL |
| | hexanal butane-2,3-diol acetal | FL |
| | hexanal dihexyl acetal | FL/FR |
| | hexanal octane-1,3-diol acetal | FL |
| (Z)-3- | hexenoic acid | FL |
| | hexyl (E)-2-hexenoate | FL |
| | melaleuca leucadendron var. cajuputi leaf oil | FL/FR |
| | melissa absolute replacer | FL/FR |
| | melissa oil | FL |
| | methyl 2-hexenoate | FL/FR |
| 3-( | methyl thio) hexanal | FL |
| 4- | methyl-2-[2-(methyl thio)ethyl]-1,3-oxathiane | |
| (E)-6- | methyl-3-hepten-2-one | FL/FR |
| 6- | methyl-3-hepten-2-one | FL/FR |
| | mistletoe absolute | |
| (E,E)-3,5- | octadien-2-one | FL |
| (E,Z)-3,5- | octadien-2-one | |
| (S)-1- | octen-3-ol | FL/FR |
| 2- | octenal | FL/FR |
| 3- | octyl butyrate | FL |
| | perilla leaf oil | FL/FR |
| | prenyl senecioate | FL/FR |
| | propylene acetal | FL/FR |
| | seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| | tagete oil rwanda | |
| alpha- | thujene | |
| ortho- | vinyl anisole | FL |
| | viridiflorol | FL/FR |
| aldehydic |
| 1- | undecanol | FL/FR |
| aromatic |
| laevo- | perillaldehyde | FL/FR |
| balsamic |
| | styrax gum (liquidambar styraciflua) | FL |
| bitter |
| (E,Z,Z)-2,4,7- | tridecatrienal | FL/FR |
| cheesy |
| iso | valeric acid | FL/FR |
| citrus |
| | lemon carbonyls | FL |
| | lemon lime flavor | FL |
| | litsea cubeba fruit oil | FL/FR |
| | verbena absolute france | FL/FR |
| cocoa |
| iso | butyl phenyl acetate | FL/FR |
| cooling |
| | theaspirane | FL/FR |
| creamy |
| 3- | hepten-2-one | FL/FR |
| earthy |
| | geosmin | FL/FR |
| fatty |
| 2,4- | decadienal | FL |
| (E,E)-2,4- | heptadienal | FL |
| 2- | heptyl furan | FL/FR |
| (Z)-3- | hexen-1-yl benzoate | FL/FR |
| 2,4- | nonadien-1-ol | FL/FR |
| 2,4- | nonadienal | FL |
| (E)-2- | octenal | FL/FR |
| floral |
| | cocoa pentenal | FL/FR |
| | dimethyl benzyl carbinyl butyrate | FL/FR |
| 3,7- | dimethyl-6-octenoic acid | FL/FR |
| 4,6- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
| 2,4- | dimethyl-alpha-allyl-3-cyclohexene methanol | |
| | geranium oil egypt | FL/FR |
| | methyl phenyl acetate | FL/FR |
| beta- | naphthyl methyl ketone | FL/FR |
| | ylang ylang flower oil I | FL/FR |
| fruity |
| | butyl heptanoate | FL/FR |
| | cinnamyl isobutyrate | FL/FR |
| | ethyl 2-ethyl acetoacetate | FL/FR |
| | ethyl hexanoate | FL/FR |
| | lilac acetaldehyde | FL/FR |
| | methyl (E)-2-octenoate | FL/FR |
| | methyl 2-methyl butyrate | FL/FR |
| para- | methyl benzyl acetate | FL/FR |
| 2- | methyl-2-pentenal | FL/FR |
| | neryl formate | FL/FR |
| | octen-1-yl cyclopentanone | FL/FR |
| | rose butanoate | FL/FR |
| | tagete oil CO2 extract | FL/FR |
| green |
| | anethum graveolens herb tincture | FL/FR |
| iso | butyl angelate | FL/FR |
| iso | butyl methyl ketone | FL/FR |
| 2-iso | butyl-3-methyl pyrazine | FL/FR |
| (+)-alpha- | campholenic aldehyde | FL/FR |
| | celery distillates | FL |
| 3- | decen-2-one | FL/FR |
| | dibutyl sulfide | FL/FR |
| | dihydroxyacetophenone (mixed isomers) | FL |
| | dodecanal dimethyl acetal | FL/FR |
| alpha- | farnesene | FL/FR |
| alpha- | farnesene isomer | FL/FR |
| | heptanal (aldehyde C-7) | FL/FR |
| (Z)-4- | heptenal | FL/FR |
| | heptyl heptanoate | FL/FR |
| | hexanal (aldehyde C-6) | FL/FR |
| (E)-4- | hexen-1-ol | |
| (Z)-3- | hexenal | FL/FR |
| 3- | hexenyl 2-methyl butyrate | FL/FR |
| | marigold pot absolute | FL/FR |
| (E,Z)-3,6- | nonadien-1-ol | FL/FR |
| (E,Z)-2,6- | nonadienal | FL/FR |
| 3- | nonanone | FL/FR |
| (E)-2- | nonenal | FL/FR |
| | ocimene quintoxide | FL/FR |
| (E,E)-2,4- | octadienal | FL |
| (E)-2- | octen-1-yl acetate | FL/FR |
| 1- | octen-3-yl acetate | FL/FR |
| | terpinyl propionate | FL/FR |
| 3,5,5- | trimethyl hexanol | FL/FR |
| herbal |
| | anethum graveolens herb oil | FL/FR |
| | anthemis nobilis flower extract | FL/FR |
| | anthemis nobilis flower oil roman | FL/FR |
| | apium graveolens seed oil | FL/FR |
| | apium graveolens seed oil india | FL/FR |
| sweet | basil absolute | FL/FR |
| | celery seed oleoresin | FL |
| | cilantro herb oil egypt | FL/FR |
| | coriander oleoresin | FL/FR |
| | dill weed oil cuba | FL/FR |
| | dill weed oil reunion | FL/FR |
| | hop absolute | FL/FR |
| | hop oil | FL/FR |
| | marigold oil mexico | FL/FR |
| | ocimum basilicum leaf oil america | FL/FR |
| | origanum majorana oil | FL/FR |
| | origanum oil | FL/FR |
| | origanum oil greece | FL/FR |
| | petroselinum crispum seed oil CO2 extract | FL/FR |
| | prenyl salicylate | FL/FR |
| | rosmarinus officinalis extract | FL/FR |
| | rosmarinus officinalis tincture | FL/FR |
| | thyme absolute | FL/FR |
| | wormwood oil america | FL/FR |
| | wormwood oil italy | FL/FR |
| | wormwood oil poland | FL/FR |
| ketonic |
| 3- | heptanone | FL/FR |
| licorice |
| | estragole | FL/FR |
| minty |
| (-)- | menthone | FL/FR |
| | myrtenol | FL/FR |
| oily |
| iso | phytol | FL/FR |
| phenolic |
| | thymol | FL/FR |
| soapy |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| spicy |
| | allspice leaf oil | FL/FR |
| | cinnamon bark oil (cinnamomum zeylanicum) india | FL/FR |
| | cinnamon bark oil ceylon | FL/FR |
| | cinnamon oleoresin ceylon | FL/FR |
| | cinnamyl formate | FL/FR |
| | clove bud oil CO2 extract | FL/FR |
| | cola acuminata seed tincture | FL |
| | croton eluteria bark oil | FL/FR |
| | cuminaldehyde | FL/FR |
| | ginger root oil china | FL/FR |
| | levisticum officinale herb oil | FL/FR |
| ortho- | methoxycinnamaldehyde | FL/FR |
| | methyl isoeugenol | FL/FR |
| | nutmeg oil | FL/FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| | pepper tree berry oil | FL/FR |
| terpenic |
| alpha- | phellandrene | FL/FR |
| gamma- | terpinene | FL/FR |
| waxy |
| | ethyl myristate | FL/FR |
| | ethyl octanoate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | hydroxycitronellal | FL/FR |
| | mimosa absolute france | FL/FR |
| | undecanal | FL/FR |
| woody |
| | curcuma zedoaria bark extract | FL/FR |
| | guaiacyl acetate | FL/FR |
| | sabinene | FL/FR |
| | zedoary bark oil | FL/FR |
| | zedoary root oil | FL/FR |
| | zedoary root oil CO2 extract | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1- | cyclohexene-1-carboxaldehyde, 4-(1-methylethenyl)- | | 1- | cyclohexene-1-carboxaldehyde, 4-isopropenyl- | | | dihydro cuminyl aldehyde | | | dihydro cuminyl aldehyde natural | | | dihydrocuminic aldehyde | | | dihydrocuminyl aldehyde | | | dihydrocuminylaldehyde | | p- | mentha-1,8-dien-7-al | | para- | mentha-1,8-dien-7-al | | 1,8-p- | menthadien-7-al | | 4-(1- | methyl ethenyl)-1-cyclohexene-1-carboxaldehyde | | 4-(1- | methylethenyl)-1-cyclohexene-1-carboxaldehyde | | 4-(1- | methylethenyl)-1-cyclohexene1-carboxyaldehyde | | | perilla aldehyde | | | perilla aldehyde natural | | | perillaaldehyde | | | perillal | | DL- | perillaldehyde | | | perillic aldehyde | | | perillyl aldehyde | | | perillylaldehyde | | 4-( | prop-1-en-2-yl)cyclohex-1-ene-1-carbaldehyde | | 4- | prop-1-en-2-ylcyclohexene-1-carbaldehyde | | 4-iso | propenyl cyclohex-1-ene carbaldehyde | | 4-iso | propenyl-1-cyclohexene-1-carbaldehyde | | 4-iso | propenyl-1-cyclohexene-1-carboxaldehyde | | 4-iso | propenylcyclohex-1-enecarbaldehyde |
Articles:
| PubMed: | Antimicrobial activity of Ammodaucus leucotrichus fruit oil from Algerian Sahara. |
| PubMed: | Fumigant activity of eleven essential oil compounds and their selected binary mixtures against Culex pipiens pallens (Diptera: Culicidae). |
| PubMed: | Two types of alcohol dehydrogenase from Perilla can form citral and perillaldehyde. |
| PubMed: | Synthesis and antiproliferative effects of amino-modified perillyl alcohol derivatives. |
| PubMed: | Chemical composition and mosquito repellency of essential oil of Conyza newii propagated in different geographical locations of Kenya. |
| PubMed: | Effects of perillaldehyde on alternations in serum cytokines and depressive-like behavior in mice after lipopolysaccharide administration. |
| PubMed: | Dominant colonization and inheritance of Methylobacterium sp. strain OR01 on perilla plants. |
| PubMed: | Concise total synthesis of spirocurcasone. |
| PubMed: | Efficient preparation of Hangekobokuto (Banxia-Houpo-Tang) decoction by adding perilla herb before decoction is finished. |
| PubMed: | Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL. |
| PubMed: | Enhancing antioxidant capacity and reducing decay of chinese bayberries by essential oils. |
| PubMed: | Influence of the active compounds of Perilla frutescens leaves on lipid membranes. |
| PubMed: | Antibacterial activity of the essential oil and main components of two Dracocephalum species from Iran. |
| PubMed: | Development of quality assessment method for optically active food flavor chemicals. |
| PubMed: | Bioreduction of α,β-unsaturated ketones and aldehydes by non-conventional yeast (NCY) whole-cells. |
| PubMed: | (S)-Perillaldehyde azine. |
| PubMed: | Inhibitory activity of hydrosols, herbal teas and related essential oils against filament formation and the growth of Candida albicans. |
| PubMed: | Chemical composition and antimicrobial activity of the extracts of Kefe cumin (Laser trilobum L.) fruits from different regions. |
| PubMed: | Preliminary analysis on essential oil composition of Perilla L. cultivated in Lithuania. |
| PubMed: | A nine-step total synthesis of (-)-platencin. |
| PubMed: | Site-saturation mutagenesis of tryptophan 116 of Saccharomyces pastorianus old yellow enzyme uncovers stereocomplementary variants. |
| PubMed: | Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens. |
| PubMed: | Fragrant unsaturated aldehydes elicit activation of the Keap1/Nrf2 system leading to the upregulation of thioredoxin expression and protection against oxidative stress. |
| PubMed: | Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. |
| PubMed: | Conformational flexibility in terpenes: vibrational circular dichroism (VCD), infrared and Raman study of S-(-)-perillaldehyde. |
| PubMed: | The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity. |
| PubMed: | Opposite stereochemical courses for enzyme-mediated alkene reductions of an enantiomeric substrate pair. |
| PubMed: | Increasing antioxidant activity and reducing decay of blueberries by essential oils. |
| PubMed: | Influence of cinnamon and clove essential oils on the D- and z-values of Escherichia coli O157:H7 in apple cider. |
| PubMed: | Parectadial, a monoterpenoid from the defensive spray of Parectatosoma mocquerysi. |
| PubMed: | Synthesis and biological activity of novel pyranopyrones derived from engineered aromatic polyketides. |
| PubMed: | Biotransformation of terpenoids by mammals, microorganisms, and plant-cultured cells. |
| PubMed: | Antimicrobial effect of trans-cinnamaldehyde, (-)-perillaldehyde, (-)-citronellal, citral, eugenol and carvacrol on airborne microbes using an airwasher. |
| PubMed: | Analysis by gas chromatography-mass spectrometry of the volatiles from the fruits of Ammodaucus leucotrichus subsp. leucotrichus and subsp. nanocarpus grown in North Africa and the Canary Islands, respectively. |
| PubMed: | Vasodilative effect of perillaldehyde on isolated rat aorta. |
| PubMed: | Fumigant toxicity of the essential oils of some African plants against Anopheles gambiae sensu stricto. |
| PubMed: | Repellency of essential oils of some Kenyan plants against Anopheles gambiae. |
| PubMed: | Antibacterial activities of naturally occurring compounds against antibiotic-resistant Bacillus cereus vegetative cells and spores, Escherichia coli, and Staphylococcus aureus. |
| PubMed: | Essential oils: their antibacterial properties and potential applications in foods--a review. |
| PubMed: | Study of the carbonyl products of terpene/OH radical reactions: detection of the 2,4-DNPH derivatives by HPLC-MS. |
| PubMed: | Action of different monoterpenic compounds against Anisakis simplex s.l. L3 larvae. |
| PubMed: | Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro. |
| PubMed: | Synthesis of both enantiomers of isorobinal, a novel cyclic monoterpene isolated from the astigmatid mite, Rhizoglyphus sp. |
| PubMed: | Bactericidal activities of plant essential oils and some of their isolated constituents against Campylobacter jejuni, Escherichia coli, Listeria monocytogenes, and Salmonella enterica. |
| PubMed: | Carvone and perillaldehyde interfere with the serum-induced formation of filamentous structures in Candida albicans at substantially lower concentrations than those causing significant inhibition of growth. |
| PubMed: | Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat. |
| PubMed: | Effects of branched cyclodextrins on the solubility and stability of terpenes. |
| PubMed: | Quantification of carvone, cineole, perillaldehyde, perillyl alcohol and sobrerol by isocratic high-performance liquid chromatography. |
| PubMed: | Insecticidal activity of monoterpenoids to western corn rootworm (Coleoptera: Chrysomelidae), twospotted spider mite (Acari: Tetranychidae), and house fly (Diptera: Muscidae). |
| PubMed: | Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. |
| PubMed: | cDNA cloning, characterization, and functional expression of 4S-(-)-limonene synthase from Perilla frutescens. |
| PubMed: | Genetic analysis of essential oil variants in Perilla frutescens. |
| PubMed: | Absolute configuration of a new mosquito repellent, (+)-eucamalol and the repellent activity of its epimer. |
| PubMed: | [Constituents of essential oils from leaves, stems, and fruits of Perilla frutescens (L.) Britt]. |
| PubMed: | Olfactory sensitivity of two sympatric species of rice leaf folders (Lepidoptera: Pyralidae) to plant volatiles. |
| PubMed: | Hepatic microsomal oxygenation of aldehydes to carboxylic acids. |
| PubMed: | Terpenoid biotransformation in mammals. V. Metabolism of (+)-citronellal, (+-)-7-hydroxycitronellal, citral, (-)-perillaldehyde, (-)-myrtenal, cuminaldehyde, thujone, and (+-)-carvone in rabbits. |
| PubMed: | [Pharmacological studies on Perillae Herba. I. Neuropharmacological action of water extract and perillaldehyde (author's transl)]. |
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