verbena absolute france
aloysia triphylla absolute france
 
Notes:
Do not use on any part of the body because of sensitizing potential.tsca definition 2008: extractives and their physically modified derivatives. aloysia triphylla, verbenaceae.
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Name: lippia citriodora absolute
CAS Number: 8024-12-2 
Name: aloysia citriodora extract
CAS Number: 85116-63-8 
ECHA EC Number: 285-215-0
Category: flavor and fragrance agents
 
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FDA Mainterm (SATF):8024-12-2 ; LEMON VERBENA, OIL (LIPPIA CITRIODORA)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
 water, 84.71 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
 
Odor Type: citrus
 
Odor Strength: medium
 
 green  tea  hay  herbal  sweet  citrus  
Odor Description:
at 100.00 %. 
green tea hay herbal sweet citrus
 
 green  tea  hay  herbal  sweet  citrus  
Odor Description:
Green, tea-like, hay, herbal with a sweet citrus nuance
Mosciano, Gerard P&F 17, No. 6, 41, (1992)
 
 
Flavor Type: citrus
 
 sweet  lemon  citrus  spicy  waxy  hay  
Taste Description:
at 30.00 ppm.  
Sweet, lemon, citrus, spice, waxy, with a hay-like nuance
Mosciano, Gerard P&F 17, No. 6, 41, (1992)
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
A. Fakhry
For experimental / research use only.
Verbena Absolute
Biolandes Parfumerie
Verbena Absolute France
Photo Gallery
Indukern F&F
VERBENA ABSOLUTE
Reincke & Fichtner
Verbena Absolute
Robertet
VERBENA
Pure & Nat
The Perfumers Apprentice
Verbena absolute (France) J.Steele
Odor: Rich green lemon notes
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Safety Information:
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
R 43 - May cause sensitisation by skin contact.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  5000 mg/kg
Food and Chemical Toxicology. Vol. 30, Pg. 137S, 1992.

Dermal Toxicity:
skin-rabbit LD50 5000 mg/kg
Food and Chemical Toxicology. Vol. 30, Pg. 137S, 1992.

skin-guinea pig LD50 > 5000 mg/kg
Food and Chemical Toxicology. Vol. 30, Pg. 137S, 1992.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect: Dermal sensitization, Phototoxicity
IFRA fragrance material specification:
 Verbena absolute obtained from Lippia citriodora Kunth, should not be used as a fragrance ingredient at a level over 1% in fragrance compounds. This recommendation is based on test results of RIFM showing sensitization reaction at 12% and no sensitization reaction at 2%. There is no evidence of photoxicity at 100% on hairless mice (private communication to IFRA).
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
citral Max. Found: 25.6 % and Reason: Sensitization
citronellol Max. Found: 0.45 % and Reason: Sensitization
eugenol Max. Found: 0.55 % and Reason: Sensitization
geraniol Max. Found: 4.1 % and Reason: Sensitization
methyl eugenol Max. Found: 0.1 % and Reason: Sensitization
trans-asarone Max. Found: 0.1 % and Reason: Carcinogenicity
cis-asarone Max. Found: 0.01 % and Reason: Carcinogenicity
alpha-cedrene Max. Found: 0.5 % and Reason: Sensitization
beta-cedrene Max. Found: 0.1 % and Reason: Sensitization
IFRA: View Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.12 %
Category 2: Products applied to the axillae
0.037 %
Category 3: Products applied to the face/body using fingertips
0.74 %
Category 4: Products related to fine fragrance
0.69 %
 Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.17 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.17 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.17 %
Category 5D: Baby Creams, baby Oils and baby talc
0.17 %
Category 6: Products with oral and lip exposure
0.40 %
 Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
1.40 %
Category 7B: Leave-on products applied to the hair with some hand contact
1.40 %
Category 8: Products with significant anogenital exposure
0.072 %
Category 9: Products with body and hand exposure, primarily rinse off
1.30 %
 Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
4.80 %
Category 10B: Household aerosol/spray products
4.80 %
 Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
2.70 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
2.70 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction
 Notes:
IFRA FLAVOR REQUIREMENTS:

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.

 
Recommendation for verbena absolute france flavor usage levels up to:
  30.0000 ppm in the finished product.
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 8024-12-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WGK Germany: 2
 lippia citriodora absolute
Chemidplus: 008024122
 aloysia citriodora extract
Chemidplus: 085116638
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References:
 lippia citriodora absolute
Canada Domestic Sub. List: 8024-12-2
Pubchem (sid): 3730676
 aloysia citriodora extract
Canada Domestic Sub. List: 85116-63-8
Pubchem (sid): 3777682
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Other Information:
Export Tariff Code: 3301.90.5000
Wikipedia: View
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 verbena absolute spainFL/FR
 yerba mate leaf oilFL/FR
balsamic
isobornyl acetateFL/FR
isobornyl phenyl acetateFL/FR
 fenchyl acetateFL/FR
chocolate
isobutyl phenyl acetateFL/FR
citrus
 abronia fragranceFR
beta-bisabololFL/FR
 citral diethyl acetalFL/FR
 citral dimethyl acetalFL/FR
2-heptanolFL/FR
 heptyl phenyl acetate 
 lemon verbena oil 
 lemon verbena oil turkey 
 lemongrass oilFL/FR
 lime oil expressed floridaFL/FR
 melissa oil slovak republic 
alpha-methylene citronellalFR
 ocimum americanum leaf oilFR
 verbena fragranceFR
 verbena oil replacerFR
 verbena oil spainFL/FR
 verbena oil terpenelessFL/FR
 verbena specialtyFR
coconut
 coconut lime verbena fragranceFR
(R)-gamma-hexalactone 
earthy
(Z)-4-octen-1-olFL/FR
floral
 citronellalFL/FR
 citronellyl benzoateFL/FR
 freesia acetateFR
 lavender oilFL/FR
para-methyl benzyl acetateFL/FR
 methyl benzyl acetate (mixed ortho-,meta-,para-)FL/FR
 petitgrain lemon oilFL/FR
 phenyl amyl alcoholFL/FR
 rhodinyl propionateFL/FR
 rose undeceneFR
fruity
 cinnamyl isobutyrateFL/FR
(E)-2-nonen-1-yl acetateFL/FR
sesquiphellandrene 
fungal
 hydroxymethyl hexyl ethyl ketoneFL/FR
green
 heptyl acetateFL/FR
 magnolia flower oilFL/FR
hay
 woodruff absoluteFR
herbal
 arnica flower oilFR
 clary sage absoluteFL/FR
 coriander oleoresinFL/FR
 lavender concreteFL/FR
 matricaria chamomilla flower oilFL/FR
curled parsley seed oilFL/FR
laevo-perillaldehydeFL/FR
 perillaldehydeFL/FR
 tea leaf absoluteFL/FR
alpha-terpinyl acetateFL/FR
 tilia cordata flowerCS
 tilia cordata flower extractFL/FR
honey
 methyl phenyl acetateFL/FR
leathery
black tea leaf absoluteFL/FR
minty
dextro-dihydrocarvoneFL/FR
 caraway seed oleoresinFL/FR
4-carvomenthenolFL/FR
 gingergrass oilFR
(R)-gamma-heptalactone 
 hollyberry fragranceFR
tea
 camellia oleifera leaf extractFL/FR
terpenic
para-cymeneFL/FR
 frankincense oilFL/FR
tobacco
2,6,6-trimethyl-2-hydroxycyclohexanoneFL/FR
tonka
 deertongue oleoresinFR
 flouve absoluteFR
woody
(E)-beta-farneseneFL/FR
 methyl ionone terpenes 
alpha-terpineneFL/FR
 
For Flavor
 
No flavor group found for these
isobornyl phenyl acetateFL/FR
 capsicum oleoresin CO2 extractFL
 citronellyl benzoateFL/FR
(E)-beta-farneseneFL/FR
(R)-gamma-heptalactone 
 heptyl phenyl acetate 
(R)-gamma-hexalactone 
 hydroxymethyl hexyl ethyl ketoneFL/FR
 lemon verbena oil 
 lemon verbena oil turkey 
 magnolia flower oilFL/FR
 melissa oil slovak republic 
 methyl benzyl acetate (mixed ortho-,meta-,para-)FL/FR
 methyl ionone terpenes 
(Z)-4-octen-1-olFL/FR
sesquiphellandrene 
 phenyl amyl alcoholFL/FR
2,6,6-trimethyl-2-hydroxycyclohexanoneFL/FR
 verbena absolute spainFL/FR
 yerba mate leaf oilFL/FR
acidic
(E)-2-hexenoic acidFL
aromatic
laevo-perillaldehydeFL/FR
balsamic
 styrax gum (liquidambar styraciflua)FL
citrus
beta-bisabololFL/FR
 citral diethyl acetalFL/FR
 citral dimethyl acetalFL/FR
 lemon verbena distillatesFL
 lemongrass oilFL/FR
 lime oil expressed floridaFL/FR
 petitgrain lemon oilFL/FR
 verbena oil franceFL
 verbena oil moroccoFL
 verbena oil spainFL/FR
 verbena oil terpenelessFL/FR
cocoa
isobutyl phenyl acetateFL/FR
cooling
4-carvomenthenolFL/FR
floral
 citronellalFL/FR
 methyl phenyl acetateFL/FR
fruity
 cinnamyl isobutyrateFL/FR
2-heptanolFL/FR
para-methyl benzyl acetateFL/FR
 rhodinyl propionateFL/FR
green
 clary sage absoluteFL/FR
dextro-dihydrocarvoneFL/FR
 heptyl acetateFL/FR
herbal
 coriander oleoresinFL/FR
 lavender concreteFL/FR
 lavender oilFL/FR
 matricaria chamomilla flower oilFL/FR
curled parsley seed oilFL/FR
 tilia cordata flower extractFL/FR
spicy
 caraway seed oleoresinFL/FR
 perillaldehydeFL/FR
tea
 camellia oleifera leaf extractFL/FR
 tea leaf absoluteFL/FR
black tea leaf absoluteFL/FR
terpenic
para-cymeneFL/FR
alpha-terpineneFL/FR
tropical
 coconut lime verbena flavorFL
waxy
(E)-2-nonen-1-yl acetateFL/FR
woody
isobornyl acetateFL/FR
 fenchyl acetateFL/FR
 frankincense oilFL/FR
alpha-terpinyl acetateFL/FR
 
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Potential Uses:
 citrusFL
 hay new mown hayFR
 lemonFL
 teaFL
 tobaccoFR
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Occurrence (nature, food, other): note
 lippia citriodora
Search Trop  Picture
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Synonyms:
 aloysia triphylla absolute france
 lippia citriodora absolute france
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Articles:
PubMed: Ethnobotanical survey of medicinal plants used by people in Oriental Morocco to manage various ailments.
PubMed: Phenylpropanoids and their metabolites are the major compounds responsible for blood-cell protection against oxidative stress after administration of Lippia citriodora in rats.
PubMed: Comparative study on in vitro activities of citral, limonene and essential oils from Lippia citriodora and L. alba on yellow fever virus.
PubMed: Chromatographic and mass spectrometric characterization of essential oils and extracts from Lippia (Verbenaceae) aromatic plants.
PubMed: Evaluation of different extraction approaches for the determination of phenolic compounds and their metabolites in plasma by nanoLC-ESI-TOF-MS.
PubMed: Antimicrobial activity of food-compatible plant extracts and chitosan against naturally occurring micro-organisms in tomato juice.
PubMed: A randomized, double-blinded, placebo-controlled study of the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management.
PubMed: Antihyperalgesic activity of verbascoside in two models of neuropathic pain.
PubMed: Phytoestrogens enhance antioxidant enzymes after swimming exercise and modulate sex hormone plasma levels in female swimmers.
PubMed: Antioxidant effect of lemon verbena extracts in lymphocytes of university students performing aerobic training program.
PubMed: Characterization of phenolic and other polar compounds in a lemon verbena extract by capillary electrophoresis-electrospray ionization-mass spectrometry.
PubMed: Preparation and physicochemical characterization of Ag nanoparticles biosynthesized by Lippia citriodora (Lemon Verbena).
PubMed: Virucidal activity of Colombian Lippia essential oils on dengue virus replication in vitro.
PubMed: Antimicrobial, antioxidant and cytotoxic activities and phytochemical screening of some yemeni medicinal plants.
PubMed: Authenticity control of essential oils containing citronellal and citral by chiral and stable-isotope gas-chromatographic analysis.
PubMed: Antimicrobial activity of essential oils against Helicobacter pylori.
PubMed: Studies on the antioxidant activity of Lippia citriodora infusion: scavenging effect on superoxide radical, hydroxyl radical and hypochlorous acid.
PubMed: Flavonoids from Lippia citriodora.
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