Articles:
| None found yet. Try the PubMed Search. |
N-[(ethoxycarbonyl)methyl)-p-menthane-3-carboxamide
Notes:
Used as a food additive [EAFUS]
-
Augustus Oils Ltd The Premier Supplier Augustus Oils Ltd, in harmony with nature - to present it at its best... A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements. Email: Enquiries Email: Sales Email: web site enquiries Voice: +44 (0)1420 590555 Fax: +44 (0)1420 592420 Services Product(s): Ws-5
-
-
BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 68489-14-5 Glycine, N-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, ethyl ester
-
-
Lluch Essence S.L. A family company dedicated to sales and distribution Flexibility, availability, price and quality. Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world. Email: Info Voice: 34 93 379 38 49 Fax: 34 93 370 65 04 Linkedin Product(s): WS-5
-
-
M&U International LLC Steady supply & demand Meeting customers increasing demands at home as well as abroad. M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers. Email: Sales US Email: Sales Voice: +86-21-32515501 60762991 60762992 Fax: +86-21-32515502 64204960 US Voice: 908-359-9000 US Fax: 908-359-9002 News Product(s): A0231 WS-5, Kosher
-
-
O'Laughlin Industries Inc. Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics Leading the Flavor and Fragrance Industry since 1980. O'Laughlin was established in 1980 by its owner and chief executive Michael O'Laughlin, when he moved to Beijing, China and established a small office. Since then it has grown to be a world class producer of chemicals, with significant production facilities in China, and distribution and sales in all major world markets. Email: Sales US Email: John Gick Voice: (852) 2527-1031 Fax: (852) 2529-0231 US Voice: (973) 376-4600 US Fax: (973) 376-4630 Product(s): 773-1007B ARCTIC SW5
-
-
OQEMA With a focus on providing the highest level of service OQEMA has established itself at the forefront of the global chemical industry. The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories. Email: Contact Us: US Email: Dean Matienzo Email: Sales US Email: Dean Matienzo - Sales Manager Voice: +44 1993 843081 Fax: +44 1993 841261 US Voice: +1 973 886 3778 US Fax: +1 973 346 1106 Linkedin Website Global Distribution Product(s): Lansense 5
-
-
Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 05-08815 N-(ETHOXYCARBONYL)METHYL)-P-MENTHANE-3-CARBOXAMIDE
-
-
SRS Aromatics Ltd For over 25 years Bringing flavour and fragrance into your world. As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply. Email: Info Email: Sales Voice: +44 (0) 1284 704076 Fax: +44 (0) 1284 760819 Twitter Linkedin News Product(s): WINSENSE WS5 COOLANT
-
-
Symrise AG Always Insiring More Symrise aroma molecules & cosmetic ingredients for unique and innovative fragrances, flavors and cosmetics. We are globally recognized as a leading provider of fragrances, flavors and active ingredients as well as aroma chemicals for the perfume, cosmetic, pharmaceutical, food and beverage industries. We combine our knowledge about consumers’ ever- changing needs with creativity and ground-breaking technologies. In doing so, we concentrate on the development of solutions that provide our customers with added value. We ensure sustained value creation by allowing our employees and shareholders to share our Company’s success. US Email: Life Essentials Email: Aroma Molecules Voice: +49 5531 90 0 Twitter Linkedin Youtube Newsroom RSS Feed Product(s): 762308 Symcool® WS-5
Useful in mint, dairy, vanilla, spices/herbs, citrus, fruits, alcoholics
-
-
Tianjin Danjun International Trade Co., LTD. Quality Products We know the Chinese chemical market well. Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service. Email: Info Email: Sales Voice: +86-15822601686 Products List: View Product(s): H-004 WS-5
-
-
Ernesto Ventós S.A. Leaders in essence We employ our five senses to do our job well. Ventos has specialized in the distribution of raw materials for the flavour and fragrance industry. With more than 1700 references permanently available from stock, we offer a just-in-time response to our customer needs, being able to deliver from 1kg to several tonnes all over the world. Email: Information US Email: Information USA Email: Gemma Parramon (Europe) US Email: Gemma Parramon (Europe) Email: Jorge Sos (Asia) Email: Ramon Rubau (America) Voice: +34 934706210 Fax: +34 934733010 US Voice: +1 856 226 7501 Instagram Linkedin Youtube Press Ads Videos Product(s): WS-5
-
| CAS Number: | 68489-14-5 |  3D/inchi
|
| FDA UNII: | Q6CA504696 | |
| XlogP3-AA: | 3.40 (est) | |
| Molecular Weight: | 269.38479000 | |
| Formula: | C15 H27 N O3 | |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) | |
| EFSA/JECFA Comments: | (Flavour Industry, 2007). CASrn refers to the (1R,2S,5R) isomer. Register name to be changed accordingly. | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1776 N-[(ethoxycarbonyl)methyl)-p-menthane-3-carboxamide |
| DG SANTE Food Flavourings: | 16.111 glycine, N-[[5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, ethyl ester |
| FEMA Number: | 4309 N-[(ethoxycarbonyl)methyl)-p-menthane-3-carboxamide |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 68489-14-5 ; N-[(ETHOXYCARBONYL)METHYL)-P-MENTHANE-3-CARBOXAMIDE |
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 80.00 to 82.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 151.00 °C. @ 2.00 mm Hg |
| Flash Point: | 374.00 °F. TCC ( 190.00 °C. ) |
| logP (o/w): | 3.384 (est) |
| Soluble in: | |
| alcohol | |
| water, 9.51 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: mentholic | |
| cooling mentholic | |
| Odor Description: at 100.00 %. | mentholic |
| Flavor Type: cooling | |
| cooling mentholic | |
| Taste Description: | cooling |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Augustus Oils |
| Ws-5 |
| Services |
| BeYonde |
| Cooling Agents-5 |
| BOC Sciences |
| For experimental / research use only. |
| Glycine, N-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, ethyl ester |
| De Monchy Aromatics |
| WINSENSE™ WS-5 |
| Ernesto Ventós |
| WS-5 |
| Kingchem Laboratories |
| WS-5
Odor: Faintly mentholic, extremely cooling |
| Lluch Essence |
| WS-5 |
| M&U International |
| WS-5, Kosher |
| O'Laughlin Industries |
| ARCTIC SW5 |
| OQEMA |
| Lansense 5 |
| Penta International |
| N-(ETHOXYCARBONYL)METHYL)-P-MENTHANE-3-CARBOXAMIDE |
| SRS Aromatics |
| WINSENSE WS5 COOLANT |
| Symrise |
| Symcool® WS-5
Flavor: High Intensity, Cooling, Fresh Useful in mint, dairy, vanilla, spices/herbs, citrus, fruits, alcoholics |
| Tianjin Danjun International |
| WS-5 |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for WS-5 usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 37.00 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 34.00 (μg/capita/day) | ||
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 7400 (μg/person/day) | ||
| NOEL (No Observed Effect Level): | 8.00 (mg/kg bw per day) | ||
| Threshold of Concern: | 90 (μg/person/day) | ||
| Structure Class: | III | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 23. Update in publication number(s): 26 | |||
| Click here to view publication 23 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 20.00000 | 200.00000 | |
| beverages(nonalcoholic): | 10.00000 | 50.00000 | |
| beverages(alcoholic): | 10.00000 | 400.00000 | |
| breakfast cereal: | 10.00000 | 50.00000 | |
| cheese: | 20.00000 | 100.00000 | |
| chewing gum: | 1000.00000 | 5000.00000 | |
| condiments / relishes: | 20.00000 | 300.00000 | |
| confectionery froastings: | 10.00000 | 200.00000 | |
| egg products: | 10.00000 | 150.00000 | |
| fats / oils: | 10.00000 | 200.00000 | |
| fish products: | 10.00000 | 100.00000 | |
| frozen dairy: | 10.00000 | 300.00000 | |
| fruit ices: | 10.00000 | 150.00000 | |
| gelatins / puddings: | 5.00000 | 100.00000 | |
| granulated sugar: | 15.00000 | 100.00000 | |
| gravies: | 10.00000 | 100.00000 | |
| hard candy: | 50.00000 | 350.00000 | |
| imitation dairy: | 10.00000 | 100.00000 | |
| instant coffee / tea: | 10.00000 | 65.00000 | |
| jams / jellies: | 10.00000 | 65.00000 | |
| meat products: | 10.00000 | 100.00000 | |
| milk products: | 10.00000 | 100.00000 | |
| nut products: | 10.00000 | 200.00000 | |
| other grains: | 10.00000 | 300.00000 | |
| poultry: | 10.00000 | 100.00000 | |
| processed fruits: | 10.00000 | 200.00000 | |
| processed vegetables: | 10.00000 | 200.00000 | |
| reconstituted vegetables: | 10.00000 | 100.00000 | |
| seasonings / flavors: | 20.00000 | 200.00000 | |
| snack foods: | 20.00000 | 300.00000 | |
| soft candy: | 10.00000 | 500.00000 | |
| soups: | 10.00000 | 100.00000 | |
| sugar substitutes: | 5.00000 | 100.00000 | |
| sweet sauces: | 10.00000 | 100.00000 | |
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). | |||
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. | |||
| average usage mg/kg | maximum usage mg/kg | ||
| Dairy products, excluding products of category 02.0 (01.0): | 10.00000 | 300.00000 | |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 10.00000 | 200.00000 | |
| Edible ices, including sherbet and sorbet (03.0): | 10.00000 | 150.00000 | |
| Processed fruit (04.1): | 10.00000 | 200.00000 | |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | 10.00000 | 200.00000 | |
| Confectionery (05.0): | 10.00000 | 200.00000 | |
| Chewing gum (05.0): | - | - | |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 10.00000 | 50.00000 | |
| Bakery wares (07.0): | 20.00000 | 200.00000 | |
| Meat and meat products, including poultry and game (08.0): | 10.00000 | 100.00000 | |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 10.00000 | 100.00000 | |
| Eggs and egg products (10.0): | - | - | |
| Sweeteners, including honey (11.0): | - | - | |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | - | - | |
| Foodstuffs intended for particular nutritional uses (13.0): | 20.00000 | 300.00000 | |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 10.00000 | 50.00000 | |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 10.00000 | 400.00000 | |
| Ready-to-eat savouries (15.0): | 50.00000 | 350.00000 | |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 10.00000 | 200.00000 | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Scientific Opinion on Flavouring Group Evaluation 94: Consideration of aliphatic amines and amides evaluated in addendum to the JECFA group aliphatic and aromatic amines and amides by JECFA View page or View pdf | |
| Statement on List of Representative Substances for Testing.
The current Statement lays down a list of substances in sub-groups with representative substances for which additional data are required prior to their evaluation through the Procedure (Regulation (EC) No 1565/2000). View page or View pdf | |
| (FGE.94Rev1): Consideration of aliphatic amines and amides evaluated in an addendum to the group of aliphatic and aromatic amines and amides evaluated by the JECFA (68th meeting) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 94, Revision 2 (FGE.94Rev2): Consideration of aliphatic amines and amides evaluated in an addendum to the group of aliphatic and aromatic amines and amides evaluated by the JECFA (68th meeting) View page or View pdf | |
| EPI System: | View |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 11615984 |
| National Institute of Allergy and Infectious Diseases: | Data |
| ethyl 2-[[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexanecarbonyl]amino]acetate | |
| Chemidplus: | 0068489145 |
References:
| Leffingwell: | Chirality or Article |
| ethyl 2-[[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexanecarbonyl]amino]acetate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 11615984 |
| Pubchem (sid): | 135329014 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB32255 |
| FooDB: | FDB009366 |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| bubble gum | FL | |
| buchu leaf | FL | |
| camphor tree bark | FL/FR | |
| cooling | FL | |
| cornmint | FL/FR | |
| geranium rose | FL/FR | |
| hyssop | FL/FR | |
| mint | FL | |
| pennyroyal | FL/FR | |
| peppermint | FL | |
| spearmint | FL | |
| tansy oil replacer | FL/FR | |
| wintergreen | FL |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| N-( | ethoxycarbonyl)methyl)-p-menthane-3-carboxamide |
| N-(( | ethoxycarbonyl)methyl)-p-menthane-3-carboxamide |
| N-[( | ethoxycarbonyl)methyl)-p-menthane-3-carboxamide |
| (( | ethoxycarbonyl)methyl)-para-menthane-3-carboxamide |
| N-(( | ethoxycarbonyl)methyl)-para-menthane-3-carboxamide |
| ethyl 2-[[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexanecarbonyl]amino]acetate | |
| ethyl N-((5-methyl-2-(isopropyl)cyclohexyl)carbonyl)glycinate | |
| ethyl N-[(2-isopropyl-5-methylcyclohexyl)carbonyl]glycinate | |
| ethyl N-[[5-methyl-2-(isopropyl)cyclohexyl]carbonyl]glycinate | |
| glycine, N-[[5-methyl-2-(1-methylethyl)cyclohexyl]carbonyl]-, ethyl ester | |
| (1R-(1alpha, 2beta,5alpha))- N-(5- | methyl-2-(1-methylethyl)cyclohexyl) carbonyl glycine ethyl ester |
| rightcool WS-5 |