|
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white colorless crystals (est) |
| Assay: | 97.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 178.80 °C. @ 760.00 mm Hg
|
| Boiling Point: | 207.40 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 4.000000 mmHg @ 25.00 °C. |
| Vapor Density: | 5.24 ( Air = 1 ) |
| Flash Point: | 148.00 °F. TCC ( 64.44 °C. )
|
| logP (o/w): | 3.040 |
| Soluble in: |
| | alcohol | | | water, 100 mg/L @ 25 °C (exp) |
| Insoluble in: |
| | water | | | glycerin |
Organoleptic Properties:
| |
| Odor Type: camphoreous |
| |
| Odor Strength: | high , recommend smelling in a 10.00 % solution or less |
| |
| Substantivity: | 160 hour(s) at 20.00 % in dipropylene glycol |
| |
| | camphoreous minty phenolic herbal woody |
Odor Description: at 10.00 % in dipropylene glycol. | camphor minty phenolic herbal woody Luebke, William tgsc, (1988) |
| |
| | camphoreous medicinal mentholic cooling green |
Odor Description:
| Camphoreous, medicinal, mentholic, with a cooling green nuance Mosciano, Gerard P&F 18, No. 2, 38, (1993) |
| |
| |
| Flavor Type: medicinal |
| |
| | medicinal camphoreous mentholic woody |
Taste Description: at 20.00 ppm. | Medicinal, camphoreous, mentholic and woody Mosciano, Gerard P&F 18, No. 2, 38, (1993) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| D-camphre 98%
|
| Berjé |
| Camphor Gum Natural
|
| Media |
| Berjé |
| Camphor Gum Synthetic
|
| BOC Sciences |
| For experimental / research use only. |
| D(+)-Camphor =>98%
|
| Diffusions Aromatiques |
| CAMPHRE-D NATUREL
|
| ECSA Chemicals |
| CAMPHOR NATURAL
|
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| Ernesto Ventós |
| CAMPHOR-D NATURAL
|
| Excellentia International |
| Camphor, d- Natural
|
| ExtraSynthese |
| For experimental / research use only. |
| (+)-Camphor (GC) ≥97% (sum of enantiomers)
|
| Fleurchem |
| camphor (gum) powder USP
|
| Fleurchem |
| camphor (gum) powder, technical
|
| Indukern F&F |
| CAMPHOR POWDER NATURAL
Odor: AROMATIC, FRESH, CONIFEROUS |
| Lluch Essence |
| CAMPHOR POWDER NATURAL
|
| M&U International |
| Camphor Powder, Kosher
|
| M&U International |
| Nat. Camphor
|
| Moellhausen |
| CAMPHOR NAT.
|
| Penta International |
| D-CAMPHOR CRYSTALS
|
| Penta International |
| D-CAMPHOR USP NATURAL
|
| PerfumersWorld |
| Camphor Powder
Odor: camphor conifer fresh-woody cool |
| Phoenix Aromas & Essential Oils |
| Camphor Natural
|
| Prodasynth |
| CAMPHOR-D, NATURAL
(> 96%) |
| R C Treatt & Co Ltd |
| Camphor Powder
|
| Reincke & Fichtner |
| D-Camphor natural
|
| Reincke & Fichtner |
| D-Camphor
|
| Sigma-Aldrich |
| D-Camphor, ≥97%, FG
Odor: medicinal; woody; vanilla |
| Certified Food Grade Products |
| Sigma-Aldrich |
| D-Camphor, natural, 96%, FG
|
| SRS Aromatics |
| CAMPHOR POWDER DEXTRO
Odor: Camphor, Minty, Phenolic, Herbal, Woody |
| TCI AMERICA |
| For experimental / research use only. |
| (+)-Camphor >98.0%(GC)
|
| Vistachem |
| Camphor, natural
|
| WholeChem |
| D-Camphor, Natural
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 10 - Flammable. R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 1310 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978.
intraperitoneal-cat LDLo 400 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978.
intravenous-mouse LD90 525 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978.
intraperitoneal-rat LDLo 3500 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978.
|
| Dermal Toxicity: |
subcutaneous-mouse LDLo 2200 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978.
subcutaneous-rat LDLo 1700 mg/kg Food and Cosmetics Toxicology. Vol. 16, Pg. 665, 1978.
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for dextro-camphor usage levels up to: | | | 3.0000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 50.00 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 11.00000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | 20.00000 |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 0.10000 |
| fruit ices: | - | 0.10000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | 1.10000 | 25.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| aldehydic |
| aldehydic |
| | decanal (aldehyde C-10) | FL/FR |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| | nonanal (aldehyde C-9) | FL/FR |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| amber |
| | angelica archangelica root oil CO2 extract | FL/FR |
| | cistus ladaniferus resinoid | FL/FR |
| animal |
| 1-oxa | spiro-4,7-dodecane | FR |
| anise |
| | anise seed oil | FL/FR |
| star | anise seed oil china | FL/FR |
| | anise seed oil colombia | FL/FR |
| star | anise seed oil spain | FL/FR |
| balsamic |
| iso | amyl benzoate | FL/FR |
| | amyris wood oil | FL/FR |
| | benzoin | FL/FR |
| siam | benzoin resinoid | FL/FR |
| | benzyl benzoate | FL/FR |
| | benzyl salicylate | FL/FR |
| dextro,laevo-iso | borneol | FL/FR |
| iso | bornyl acetate | FL/FR |
| | bornyl acetate | FL/FR |
| iso | bornyl formate | FL/FR |
| iso | bornyl propionate | FL/FR |
| | cedar forest fragrance | FR |
| | conifer acetate | FR |
| | fir balsam absolute | FR |
| | frankincense absolute | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| camphoreous |
| | cyclohexanol | FL/FR |
| | melaleuca viridiflora leaf oil | FR |
| citrus |
| | methyl heptenone | FL/FR |
| | neroli ketone | FR |
| creamy |
| | veratraldehyde | FL/FR |
| earthy |
| 2- | octanone | FL/FR |
| fatty |
| | decanol | FL/FR |
| floral |
| | aglaia odorata absolute | FR |
| alpha- | amyl cinnamaldehyde | FL/FR |
| iso | amyl salicylate | FL/FR |
| | bigarade oxide | FR |
| iso | butyl salicylate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | ho leaf oil | FR |
| | karo karounde absolute | FR |
| | karo karounde absolute replacer | FR |
| | lavender oil | FL/FR |
| | nonanol | FL/FR |
| | petitgrain bigarade oil | FL/FR |
| | phenethyl alcohol | FL/FR |
| | sambucus nigra flower oil CO2 extract | FR |
| 5- | tricyclodecenyl acetate | FR |
| fruity |
| | allyl cyclohexyl propionate | FL/FR |
| 3- | benzyl-4-heptanone | FL/FR |
| green |
| iso | cyclocitral (IFF) | FL/FR |
| | dicyclopentadiene propionate | FR |
| alpha- | hexyl cinnamaldehyde dimethyl acetal | FR |
| para- | methyl hydratropaldehyde | FL/FR |
| | seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| hay |
| | tobacco leaf absolute | FL/FR |
| herbal |
| | ajowan seed oil | FL/FR |
| 1- | allyl-2,2,7,7-tetramethyl cycloheptanol | FR |
| | angelica archangelica seed extract | FL/FR |
| | anthemis nobilis flower oil roman | FL/FR |
| | artemisia vestita wall. leaf oil | FR |
| | bornyl 2-methyl butyrate | FL/FR |
| | bornyl butyrate | FL/FR |
| beta- | bourbonene | FL/FR |
| 3- | butyl phthalide | FL/FR |
| delta- | cadinene | |
| | calamintha clinopodium oil | FR |
| | cardamom liquid resin | FR |
| | carum carvi fruit oil | FL/FR |
| 1,8- | cineole | FL/FR |
| | dill seed oil | FL/FR |
| | dill seed oil CO2 extract | FL/FR |
| | eucalyptus globulus oil | FL/FR |
| | eucalyptus oil replacer | FR |
| | herbal undecanone | FR |
| | immortelle flower oil | FL/FR |
| abrialis | lavandin oil | FL/FR |
| | lavandin water absolute | FL/FR |
| spike | lavender oil | FL/FR |
| 2- | methyl butyl salicylate | FL/FR |
| | origanum oil greece | FL/FR |
| alpha- | pinene | FL/FR |
| | pinocarveol | FL/FR |
| | piperitone | FL/FR |
| | rosemary oil spain | FL/FR |
| | rosemary oleoresin | FL/FR |
| | safranal | FL/FR |
| white | thyme oil | FL/FR |
| | thyme oil (thymus zygis gracillis) spain | FL/FR |
| red | thyme oil india | FL/FR |
| red | thyme oil spain | FL/FR |
| | thyme oil wild or creeping | FL/FR |
| | thymol | FL/FR |
| mentholic |
| | peppermint cyclohexanone | FL/FR |
| minty |
| | mint fragrance | FR |
| | mint specialty | FR |
| | pennyroyal oil | FL/FR |
| mossy |
| | veramoss (IFF) | FR |
| musk |
| | angelica root absolute | FL/FR |
| naphthyl |
| 1- | methyl naphthalene | FL/FR |
| nutty |
| | pentanoic acid, 3-methyl-2-oxo-, ethyl ester | FL/FR |
| orris |
| para-iso | propyl acetophenone | FL/FR |
| powdery |
| para- | anisyl alcohol | FL/FR |
| spicy |
| | bayberry fragrance | FR |
| | cardamom oil replacer | FR |
| | cassia bark oil china | FL/FR |
| | cinnamon acrolein | FL/FR |
| | clove bud oil | FL/FR |
| | clove leaf oil | FL/FR |
| | elettaria cardamomum seed oil | FL/FR |
| | elettaria cardamomum seed oil guatemala | FL/FR |
| | ginger oleoresin africa | FL/FR |
| | ginger root absolute | FL/FR |
| | ginger root oil cochin | FL/FR |
| | maja fragrance | FR |
| | myrcene | FR |
| 2- | octanol | FL/FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| white | pepper oil | FL/FR |
| black | pepper oleoresin | FL/FR |
| 4-iso | propyl-2-cyclohexenone | FL/FR |
| terpenic |
| | cypress leaf oil | FR |
| | frankincense oil | FL/FR |
| | juniperus communis fruit oil | FL/FR |
| thujonic |
| | cedarleaf oil western red | FR |
| | sage oil dalmatian | FL/FR |
| common | tansy flower oil argentina | FL/FR |
| common | tansy leaf oil dutch | FR |
| | woody ketone | FL/FR |
| tonka |
| | tonka bean absolute | FR |
| waxy |
| | ethyl laurate | FL/FR |
| woody |
| | angelica archangelica root extract | FL/FR |
| | angelica archangelica root tincture | FL/FR |
| | angelica archangelica root water | FL/FR |
| | cadinene | FL/FR |
| (+)- | camphene | FL/FR |
| | camphene | FL/FR |
| | cypress essence | FR |
| | dalbergia sissoo leaf oil | FR |
| | dihydro-alpha-terpinyl acetate | FR |
| | fougere woody fragrance | FR |
| (1R,4S)-1- | hydroxy-1,4-dimethyl spiro(4.6)undecan-2-one | |
| | laitone | FR |
| | manevoro oil | FR |
| | marine formate | FR |
| | melaleuca bracteata leaf oil | FR |
| | methyl cedryl ketone | FL/FR |
| gamma- | muurolene | |
| | origanum vulgare ssp. vulgare oil himalaya | |
| | patchouli ethanone | FR |
| | patchouli oil | FL/FR |
| | polylimonene | FL/FR |
| | santol pentenol | FR |
| | spruce needle oil canada | FL/FR |
| | tetrahydromugol | FR |
| | thuja occidentalis leaf oil | FL/FR |
| | vetiver oil haiti | FL/FR |
| | woody acetate | FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | angelica archangelica root extract | FL/FR |
| | angelica archangelica root oil CO2 extract | FL/FR |
| | angelica archangelica root tincture | FL/FR |
| | angelica archangelica root water | FL/FR |
| | benzoin | FL/FR |
| | bornyl 2-methyl butyrate | FL/FR |
| | bornyl butyrate | FL/FR |
| beta- | bourbonene | FL/FR |
| 3- | butyl phthalide | FL/FR |
| delta- | cadinene | |
| (+)- | camphene | FL/FR |
| | cistus ladaniferus resinoid | FL/FR |
| | cyclohexanol | FL/FR |
| (1R,4S)-1- | hydroxy-1,4-dimethyl spiro(4.6)undecan-2-one | |
| 2- | methyl butyl salicylate | FL/FR |
| 3- | methyl cyclohexanone | FL |
| 1- | methyl pyrrole | FL |
| gamma- | muurolene | |
| | origanum vulgare ssp. vulgare oil himalaya | |
| | polylimonene | FL/FR |
| 4-iso | propyl-2-cyclohexenone | FL/FR |
| | seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| | woody ketone | FL/FR |
| aldehydic |
| | nonanal (aldehyde C-9) | FL/FR |
| anise |
| | anise seed oil | FL/FR |
| star | anise seed oil china | FL/FR |
| | anise seed oil colombia | FL/FR |
| star | anise seed oil spain | FL/FR |
| balsamic |
| siam | benzoin resinoid | FL/FR |
| | benzyl benzoate | FL/FR |
| | benzyl salicylate | FL/FR |
| iso | bornyl propionate | FL/FR |
| camphoreous |
| dextro,laevo-iso | borneol | FL/FR |
| | bornyl acetate | FL/FR |
| | camphene | FL/FR |
| | pinocarveol | FL/FR |
| citrus |
| | petitgrain bigarade oil | FL/FR |
| cooling |
| iso | butyl salicylate | FL/FR |
| spike | lavender oil | FL/FR |
| creamy |
| | veratraldehyde | FL/FR |
| dairy |
| 2- | octanone | FL/FR |
| fatty |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| floral |
| | phenethyl alcohol | FL/FR |
| fruity |
| | allyl cyclohexyl propionate | FL/FR |
| iso | amyl benzoate | FL/FR |
| para- | anisyl alcohol | FL/FR |
| 3- | benzyl-4-heptanone | FL/FR |
| grassy |
| | tobacco leaf absolute | FL/FR |
| green |
| iso | amyl salicylate | FL/FR |
| iso | cyclocitral (IFF) | FL/FR |
| | methyl heptenone | FL/FR |
| para- | methyl hydratropaldehyde | FL/FR |
| herbal |
| | ajowan seed oil | FL/FR |
| | angelica archangelica seed extract | FL/FR |
| | anthemis nobilis flower oil roman | FL/FR |
| | cardamom distillates | FL |
| | cardamom flavor | FL |
| | carum carvi fruit oil | FL/FR |
| | celery seed oleoresin | FL |
| | dill seed oil | FL/FR |
| | dill seed oil CO2 extract | FL/FR |
| | eucalyptus flavor | FL |
| | eucalyptus globulus oil | FL/FR |
| | immortelle flower oil | FL/FR |
| abrialis | lavandin oil | FL/FR |
| | lavandin water absolute | FL/FR |
| | lavender oil | FL/FR |
| | origanum oil greece | FL/FR |
| | rosemary oil spain | FL/FR |
| | rosemary oleoresin | FL/FR |
| white | thyme oil | FL/FR |
| | thyme oil (thymus zygis gracillis) spain | FL/FR |
| red | thyme oil india | FL/FR |
| red | thyme oil spain | FL/FR |
| | thyme oil wild or creeping | FL/FR |
| medicinal |
| | frankincense absolute | FL/FR |
| mentholic |
| | peppermint cyclohexanone | FL/FR |
| minty |
| 1,8- | cineole | FL/FR |
| | pennyroyal oil | FL/FR |
| | piperitone | FL/FR |
| musk |
| | angelica root absolute | FL/FR |
| naphthyl |
| 1- | methyl naphthalene | FL/FR |
| nutty |
| | pentanoic acid, 3-methyl-2-oxo-, ethyl ester | FL/FR |
| phenolic |
| | thymol | FL/FR |
| pine |
| | spruce beer flavor | FL |
| soapy |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| spicy |
| | cassia bark oil china | FL/FR |
| | cinnamon acrolein | FL/FR |
| | clove bud oil | FL/FR |
| | clove leaf oil | FL/FR |
| | elettaria cardamomum seed oil | FL/FR |
| | elettaria cardamomum seed oil guatemala | FL/FR |
| | ginger oleoresin africa | FL/FR |
| | ginger root absolute | FL/FR |
| | ginger root oil cochin | FL/FR |
| 2- | octanol | FL/FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| white | pepper oil | FL/FR |
| black | pepper oleoresin | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| para-iso | propyl acetophenone | FL/FR |
| terpenic |
| | juniperus communis fruit oil | FL/FR |
| thujonic |
| | sage oil dalmatian | FL/FR |
| common | tansy flower oil argentina | FL/FR |
| tropical |
| alpha- | amyl cinnamaldehyde | FL/FR |
| waxy |
| | decanal (aldehyde C-10) | FL/FR |
| | decanol | FL/FR |
| | ethyl laurate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | nonanol | FL/FR |
| woody |
| | amyris wood oil | FL/FR |
| iso | bornyl acetate | FL/FR |
| iso | bornyl formate | FL/FR |
| | cadinene | FL/FR |
| | frankincense oil | FL/FR |
| | methyl cedryl ketone | FL/FR |
| | patchouli oil | FL/FR |
| alpha- | pinene | FL/FR |
| | safranal | FL/FR |
| | spruce needle oil canada | FL/FR |
| | thuja occidentalis leaf oil | FL/FR |
| | vetiver oil haiti | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-, (1R,4R)- | | | bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R,4R)- | | (+)- | bornan-2-one | | (+)-2- | bornanone | | (1R)- * (+)-2- | bornanone | | D-2- | bornanone | | dextro-2- | bornanone | | D-2- | camphanone | | dextro-2- | camphanone | | (+)- | camphor | | (1R,4R)-(+)- | camphor | | (1R)- | camphor | | (1R)- * (+)- | camphor | | (1R)-(+)- | camphor | | (R)- | camphor | | (R)-(+)- | camphor | | D- | camphor | | D-(+)- | camphor | | D-formosa | camphor | | D-laurel | camphor | | dextro-(+)- | camphor | | dextro-formosa | camphor | | dextro-laurel | camphor | | japanese | camphor | | | camphor (gum) powder USP | | | camphor (gum) powder, technical | | | camphor flake USP24 | | | camphor gum | | | camphor gum natural | | | camphor gum synthetic | | | camphor powder | | | camphor powder natural | | | camphor powder natural USP/FCC | | | camphor powder synthetic | | | camphor-D natural | | | camphor, (1R,4R)-(+)- | | D- | gum camphor | | dextro- | gum camphor | | (R)-1,7,7- | trimethyl bicyclo(2.2.1)-2-heptanone | | (1R)-1,7,7- | trimethyl bicyclo(2.2.1)heptan-2-one | | 2-keto-1,7,7- | trimethyl norcamphane | | (R)-1,7,7- | trimethylbicyclo(2.2.1)-2-heptanone | | (1R,4R)-1,7,7- | trimethylbicyclo(2.2.1)heptan-2-one | | (1R)-1,7,7- | trimethylbicyclo(2.2.1)heptan-2-one | | (1R,4R)-1,7,7- | trimethylbicyclo[2.2.1]heptan-2-one | | (1R,4R)-1,7,7- | trimethylnorbornan-2-one | | 2-keto-1,7,7- | trimethylnorcamphane |
Articles:
| PubMed: | Total synthesis of chiriquitoxin, an analogue of tetrodotoxin isolated from the skin of a dart frog. |
| PubMed: | Hot-spot residues in the cytochrome P450cam-putidaredoxin binding interface. |
| PubMed: | Optically pure, monodisperse cis-oligodiacetylenes: aggregation- induced chirality enhancement. |
| PubMed: | [About flavouring substances and flavouring preparations regulation in the field of manufacturing of flavourings and foodstuffs]. |
| PubMed: | Reaction of an "invisible" frustrated N/B Lewis pair with dihydrogen. |
| PubMed: | Nona-coordinated chiral Eu(III) complexes with stereoselective ligand-ligand noncovalent interactions for enhanced circularly polarized luminescence. |
| PubMed: | Desymmetrization of cyclohexadienones viad-camphor-derived triazolium salt catalyzed intramolecular Stetter reaction. |
| PubMed: | In vivo antioxidant activities of essential oils and their constituents from leaves of the Taiwanese Cinnamomum osmophloeum. |
| PubMed: | Spectroscopic evidence for the unusual stereochemical configuration of an endosome-specific lipid. |
| PubMed: | Analysis of volatile compositions of Magnolia biondii pamp by steam distillation and headspace solid phase micro-extraction. |
| PubMed: | Formation of repressor-inducer-operator ternary complex: negative cooperativity of d-camphor binding to CamR. |
| PubMed: | Topological and experimental approach to the pressure-temperature-composition phase diagram of the binary enantiomer system d- and l-camphor. |
| PubMed: | Changing the substrate specificity of P450cam towards diphenylmethane by semi-rational enzyme engineering. |
| PubMed: | Breeding and identification of novel koji molds with high activity of acid protease by genome recombination between Aspergillus oryzae and Aspergillus niger. |
| PubMed: | Improvement of the embryonic stem cell test endpoint analysis by use of field potential detection. |
| PubMed: | Preparation of functionalized cyclic enol phosphates by halogen-magnesium exchange and directed deprotonation reactions. |
| PubMed: | Circularly polarized luminescence of Eu(III) complexes with point- and axis-chiral ligands dependent on coordination structures. |
| PubMed: | Highly enantioselective intramolecular Michael reactions by D-camphor-derived triazolium salts. |
| PubMed: | Resolution of planar chiral cationic (eta6-arene)tricarbonylmanganese complexes. |
| PubMed: | Biotransformations of (+/-)-geosmin by terpene-degrading bacteria. |
| PubMed: | D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - a randomized, placebo controlled double blind study. |
| PubMed: | Skin disposition of d-camphor and l-menthol alone and together. |
| PubMed: | Tetraaquabis(D-camphor-10-sulfonato)calcium(II). |
| PubMed: | A role of the heme-7-propionate side chain in cytochrome P450cam as a gate for regulating the access of water molecules to the substrate-binding site. |
| PubMed: | Diamagnetic lanthanide tris beta-diketonates as organic-soluble chiral NMR shift reagents. |
| PubMed: | D-Camphor-derived triazolium salts for catalytic intramolecular crossed aldehyde-ketone benzoin reactions. |
| PubMed: | Hexaaqua-magnesium(II) bis-(d-camphor-10-sulfonate). |
| PubMed: | Polyploid formation between Aspergillus niger and Trichoderma viride for enhanced citric acid production from cellulose. |
| PubMed: | Preparation of highly conductive, self-assembled gold/polyaniline nanocables and polyaniline nanotubes. |
| PubMed: | Expression, crystallization and preliminary diffraction studies of the Pseudomonas putida cytochrome P450cam operon repressor CamR. |
| PubMed: | [Efficacy and safety of a herbal drug containing hawthorn berries and D-camphor in hypotension and orthostatic circulatory disorders/results of a retrospective epidemiologic cohort study]. |
| PubMed: | A randomized trial of Korodin Herz-Kreislauf-Tropfen as add-on treatment in older patients with orthostatic hypotension. |
| PubMed: | Detection of a high-barrier conformational change in the active site of cytochrome P450cam upon binding of putidaredoxin. |
| PubMed: | L358P mutation on cytochrome P450cam simulates structural changes upon putidaredoxin binding: the structural changes trigger electron transfer to oxy-P450cam from electron donors. |
| PubMed: | Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam. |
| PubMed: | Discriminative power of an assay for automated in vitro screening of teratogens. |
| PubMed: | NMR study on the structural changes of cytochrome P450cam upon the complex formation with putidaredoxin. Functional significance of the putidaredoxin-induced structural changes. |
| PubMed: | Dose-response related efficacy in orthostatic hypotension of a fixed combination of D-camphor and an extract from fresh crataegus berries and the contribution of the single components. |
| PubMed: | A delicate balance of energetics. Subtleties associated with alpha-ketol-based bridge migration to afford 9-keto-10beta-p-methoxybenzyloxytaxanes. |
| PubMed: | Optical cell with a temperature-control unit for a vacuum-ultraviolet circular dichroism spectrophotometer. |
| PubMed: | Camphor-Crataegus berry extract combination dose-dependently reduces tilt induced fall in blood pressure in orthostatic hypotension. |
| PubMed: | Selection of test chemicals for the ECVAM international validation study on in vitro embryotoxicity tests. European Centre for the Validation of Alternative Methods. |
| PubMed: | Energetic stabilization of d-camphor via weak neutral currents. |
| PubMed: | Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system. |
| PubMed: | Putidaredoxin-cytochrome P450cam interaction. |
| PubMed: | X-ray crystal structure and catalytic properties of Thr252Ile mutant of cytochrome P450cam: roles of Thr252 and water in the active center. |
| PubMed: | Roles of the axial push effect in cytochrome P450cam studied with the site-directed mutagenesis at the heme proximal site. |
| PubMed: | In vitro transcriptional analysis of the cytochrome P-450cam hydroxylase operon. |
| PubMed: | Construction and application of MCBL plate for facilitation of chromosome recombination in fungi. |
| PubMed: | Putidaredoxin-cytochrome p450cam interaction. Spin state of the heme iron modulates putidaredoxin structure. |
| PubMed: | Reproductive toxicity studies of D-camphor in rats and rabbits. |
| PubMed: | Preparation of Enantiomerically Enriched (2R,3R)- or (2S,3S)-trans-2,3-Diaryloxiranes via Camphor-Derived Sulfonium Ylides. |
| PubMed: | NMR studies of recombinant cytochrome P450cam mutants. |
| PubMed: | Purification and characterization of a cam repressor (CamR) for the cytochrome P-450cam hydroxylase operon on the Pseudomonas putida CAM plasmid. |
| PubMed: | Substrate interactions in cytochrome P-450: correlation between carbon-13 nuclear magnetic resonance chemical shifts and C-O vibrational frequencies. |
| PubMed: | Thermodynamic aspects of the CO-binding reaction to cytochrome P-450cam. Relevance with their biological significance and structure. |
| PubMed: | Heterologous expression of the cytochrome P450cam hydroxylase operon and the repressor gene of Pseudomonas putida in Escherichia coli. |
| PubMed: | High-pressure flash photolysis study of hemoprotein: effects of substrate analogues on the recombination of carbon monoxide to cytochrome P450CAM. |
| PubMed: | Significant contribution of arginine-112 and its positive charge of Pseudomonas putida cytochrome P-450cam in the electron transport from putidaredoxin. |
| PubMed: | Spectral intermediate in the reaction of ferrous cytochrome P450cam with superoxide anion. |
| PubMed: | Putative functions of phenylalanine-350 of Pseudomonas putida cytochrome P-450cam. |
| PubMed: | Transcription of the cam operon and camR genes in Pseudomonas putida PpG1. |
| PubMed: | Development of bacterial cytochrome P-450(cam) (cytochrome m) production. |
| PubMed: | [d-Camphor reference standard (Control 911) and dl-Camphor Reference Standard (Control 911) of the National Institute of Hygienic Sciences]. |
| PubMed: | Observation of the O-O stretching Raman band for cytochrome P-450cam under catalytic conditions. |
| PubMed: | Dopaminergic unique affinity of tetrahydroberberine and l-tetrahydroberberine-d-camphor sulfonate. |
| PubMed: | [d-Camphor Reference Standard (Control 901) and dl-Camphor Reference Standard (Control 901) of National Institute of Hygienic Sciences]. |
| PubMed: | Cloning and nucleotide sequences of NADH-putidaredoxin reductase gene (camA) and putidaredoxin gene (camB) involved in cytochrome P-450cam hydroxylase of Pseudomonas putida. |
| PubMed: | Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation. |
| PubMed: | Theoretical study of the product specificity in the hydroxylation of camphor, norcamphor, 5,5-difluorocamphor, and pericyclocamphanone by cytochrome P-450cam. |
| PubMed: | Oxime-metabolizing activity of liver aldehyde oxidase. |
| PubMed: | [D-camphor-beta-sulfonic acid as an ion-pair reagent for the determination of biogenic amines and their metabolites in the rat brain by reverse phase high performance liquid chromatography]. |
| PubMed: | Anticonvulsant properties of spirohydantoins derived from optical isomers of camphor. |
| PubMed: | [Central depressant effect of l-tetrahydroberberine-d-camphor sulfonate (THB-CS). Electroencephalographic study]. |
| PubMed: | High-pressure investigations of cytochrome P-450 spin and substrate binding equilibria. |
| PubMed: | Novel reactivity of cytochrome P-450-CAM. Methyl hydroxylation of 5,5-difluorocamphor. |
| PubMed: | Regioselectivity in the cytochromes P-450: control by protein constraints and by chemical reactivities. |
| PubMed: | Proton coupling in the ligand-binding reaction of ferric cytochrome P-450 from Pseudomonas putida. |
| PubMed: | Sequential cold-sensitive mutations in Aspergillus fumigatus. II. Analysis by the parasexual cycle. |
| PubMed: | Cytochrome P-450cam and putidaredoxin interaction during electron transfer. |
| PubMed: | Magnetic circular dichroism of Pseudomonas putida cytochrome P-450 in near infrared region. |
| PubMed: | Growth inhibition of Vibrio cholerae by d-camphor. |
| PubMed: | Inhibition of oxidative metabolism in Escherichia coli by d-camphor and restoration of oxidase activity by quinones. |
| PubMed: | Growth inhibition of Escherichia coli strain 82-r by d-camphor. |
| PubMed: | Proton magnetic resonance reveals high-spin iron (II) in ferrous cytochrome P450 cam from Pseudomonas putida. |
| PubMed: | Induction specificity and catabolite repression of the early enzymes in camphor degradation by Pseudomonas putida. |
| PubMed: | Approximation of rotational strengths from molar rotation data and generation of rotatory dispersion curves for d-camphor-10-sulfonate. |
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