Articles:
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acetamide, 2-(4-methylphenoxy)-N-1H-pyrazol-3-yl-N-(2-thienylmethyl)-
Notes:
None found
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Chemical sources Association Inc Exchange of knowledge Need This Item for Flavor? You can contact the Chemical Sources Association. Events Links Product(s):
-
| CAS Number: | 1374760-95-8 |  3D/inchi
|
| FDA UNII: | OW22Q34GIJ | |
| Nikkaji Web: | J3.484.487I | |
| XlogP3-AA: | 3.20 (est) | |
| Molecular Weight: | 327.40689000 | |
| Formula: | C17 H17 N3 O2 S | |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) | |
| EFSA/JECFA Comments: | Purity (UPLC-UV, 254 nm) = 99% peak area | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 2237 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide |
| FEMA Number: | 4809 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
Physical Properties:
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 115.00 to 116.50 °C. @ 760.00 mm Hg |
| Soluble in: | |
| water, 21.91 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Flavor Type: cooling | |
| cooling | |
| Taste Description: | cooling |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the CSA |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide usage levels up to: | |||
| not for fragrance use. | |||
| Threshold of Concern: | 90 (μg/person/day) | ||
| Structure Class: | III | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 27. Update in publication number(s): 28 | |||
| Click here to view publication 27 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 3.00000 | 15.00000 | |
| beverages(nonalcoholic): | 1.00000 | 3.00000 | |
| beverages(alcoholic): | 2.00000 | 6.00000 | |
| breakfast cereal: | 3.00000 | 15.00000 | |
| cheese: | - | - | |
| chewing gum: | 75.00000 | 150.00000 | |
| condiments / relishes: | 3.00000 | 15.00000 | |
| confectionery froastings: | 5.00000 | 30.00000 | |
| egg products: | 3.00000 | 15.00000 | |
| fats / oils: | 3.00000 | 15.00000 | |
| fish products: | - | - | |
| frozen dairy: | 1.00000 | 3.00000 | |
| fruit ices: | 1.00000 | 3.00000 | |
| gelatins / puddings: | 1.00000 | 3.00000 | |
| granulated sugar: | - | - | |
| gravies: | 3.00000 | 15.00000 | |
| hard candy: | 5.00000 | 15.00000 | |
| imitation dairy: | 1.00000 | 3.00000 | |
| instant coffee / tea: | 1.00000 | 3.00000 | |
| jams / jellies: | 1.00000 | 3.00000 | |
| meat products: | 3.00000 | 15.00000 | |
| milk products: | 1.00000 | 3.00000 | |
| nut products: | 1.00000 | 3.00000 | |
| other grains: | - | - | |
| poultry: | 3.00000 | 15.00000 | |
| processed fruits: | 1.00000 | 3.00000 | |
| processed vegetables: | 3.00000 | 15.00000 | |
| reconstituted vegetables: | 3.00000 | 15.00000 | |
| seasonings / flavors: | 3.00000 | 15.00000 | |
| snack foods: | 3.00000 | 15.00000 | |
| soft candy: | 5.00000 | 15.00000 | |
| soups: | 3.00000 | 15.00000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | 5.00000 | 15.00000 | |
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Scientific Opinion of Flavouring Group Evaluation 411 (FGE.411): 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide from chemical group 30 (miscellaneous substances) View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 67516108 |
| National Institute of Allergy and Infectious Diseases: | Data |
| 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide | |
| Chemidplus: | 1374760958 |
References:
| Leffingwell: | Chirality or Article |
| 2-(4-methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 67516108 |
| Pubchem (cas): | 1374760-95-8 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| acetamide, 2-(4-methylphenoxy)-N-1H-pyrazol-3-yl-N-(2-thienylmethyl)- | |
| 2-(4- | methyl phenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl) acetamide |
| 2-(4- | methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(2-thienylmethyl)acetamide |