Articles:
dodec-2-enal
Notes:
Cilantro is a delightful spice added to make tacos and guacamole delicious and enliven the taste and aroma of many Spanish/Mexican foods. However for some people cilantro tastes and smells like soap. A number of famous chefs abhor(ed) cilantro, including Julia Child, Ina Garten (aka Barefoot Contessa) and Top Chef Fabio Viviani. It turns out that the compound that gives Cilantro the pleasant citrus taste/smell is 2-dodecenal. If you have a mutation in an olafactory receptor, it can't distinguish between 2-dodecenal and 1-dodecenal. 1-dodecenal tastes and smells soapy. So for people who hate cilantro, 2-dodecenal looks and tastes like 1-dodecenal. [DW]
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Alfrebro LLC/ Archer Daniels Midland Company Let's get reacquainted Building great taste with aroma chemicals, extracts, and distillates The Alfrebro brand was established in the early 1900s by Alex Fries & Brothers, a Cincinnati Flavor Company. In 1980, the brand was re-launched as an aroma chemical manufacturer. Since its inception, Alfrebro’s primary focus has been to provide quality natural and high value synthetic chemicals. Email: Sarah Forbis Email: Sales Voice: 513-539-3021 Fax: 513-539-7372 US Voice: 513-539-7373 Newsroom Product(s): trans-2-DODECENAL NATURAL 10% IN MCTG trans-2-DODECENAL NATURAL 10% IN ETHYL ACETATE
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Bedoukian Research, Inc. Perfecting the Art of Chemistry Working closely with our customers to meet their requirements. Dr. Paul Bedoukian founded the company in 1972 to fill a niche as a supplier of high quality specialty aroma molecules. Today, we offer more than 350 high impact aroma chemicals, while providing custom manufacturing services to the pharmaceutical, agrochemical, and specialty chemical industries. US Email: Customer Service US Email: Customer Service US Voice: 1-203-830-4000 US Fax: 1-203-830-4010 Instagram Linkedin Recent News Products List: View Product(s): 356A 2-DODECENAL (HIGH TRANS) ≥93.0% (trans), FCC, Kosher SDS Useful as a topnote to achieve a mandarine-orange, waxy effect.
Citrus flavors, specifically orange and tangerine. Excellent for cilantro and similar herbal type flavors. Can be used to impart fatty notes of melon & cucumber.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 4826-62-4 2-DODECENAL (HIGH TRANS) FCC 95.0% (sum of isomers)
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 04-89503 TRANS-2-DODECEN-1-AL NATURAL NEAT
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| CAS Number: | 4826-62-4 |  3D/inchi
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| ECHA EINECS - REACH Pre-Reg: | 225-402-5 | |
| CoE Number: | 124 | |
| XlogP3-AA: | 4.80 (est) | |
| Molecular Weight: | 182.30654000 | |
| Formula: | C12 H22 O | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | At least 93%; secondary component 3-4% 2-dodecenoic acid. (EFSA) According to the specifcations provided (Documentation provided to EFSA nr: 1), this entry is synonymous with dodec-2(trans)-enal [FL-no: 05.144], evaluated in FGE.05Rev3 93–95% (2 E)-isomer (2–3% (2Z)-isomer and SC: 3–4% 2-dodecenoic acid | |
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1350 2-dodecenal |
| DG SANTE Food Flavourings: | 05.037 2-dodecenal |
| FEMA Number: | 2402 2-dodecenal |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 4826-62-4 ; 2-DODECENAL |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants. | |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 94.00 to 99.80 % sum of isomers |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.83900 to 0.84900 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 6.981 to 7.065 |
| Refractive Index: | 1.45200 to 1.45800 @ 20.00 °C. |
| Boiling Point: | 272.00 °C. @ 760.00 mm Hg |
| Acid Value: | 5.00 max. KOH/g |
| Vapor Pressure: | 0.010000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 200.00 °F. TCC ( 93.33 °C. ) |
| logP (o/w): | 4.847 (est) |
| Soluble in: | |
| alcohol | |
| water, 7.259 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: herbal | |
| Odor Strength: | high , recommend smelling in a 1.00 % solution or less |
| Substantivity: | > 48 hour(s) at 100.00 % |
| green citrus fruity mandarin orange herbal | |
| Odor Description: at 1.00 % in dipropylene glycol. | green citrus fruity mandarin orange herbal |
| Flavor Type: fatty | |
| fatty waxy citrus peel cilantro herbal | |
| Taste Description: | fatty waxy citrus peel cilantro herbal |
| Odor and/or flavor descriptions from others (if found). | |
| Bedoukian Research | |
| 2-DODECENAL (HIGH TRANS) ≥93.0% (trans), FCC, Kosher | |
| Odor Description: | waxy, mandarin orange Useful as a topnote to achieve a mandarine-orange, waxy effect. |
| Taste Description: | Fatty, waxy, citrus peel notes with cilantro and similar types of herbal notes Citrus flavors, specifically orange and tangerine. Excellent for cilantro and similar herbal type flavors. Can be used to impart fatty notes of melon & cucumber. |
| Alfrebro | |
| trans-2-DODECENAL NATURAL 10% IN MCTG | |
| Odor Description: | Green, Citrus, Fruity |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
perfuming agents |
Suppliers:
| Alfrebro |
| trans-2-DODECENAL NATURAL 10% IN ETHYL ACETATE |
| Alfrebro |
| trans-2-DODECENAL NATURAL 10% IN MCTG
Odor: Green, Citrus, Fruity |
| Bedoukian Research |
| 2-DODECENAL (HIGH TRANS)
≥93.0% (trans), FCC, Kosher Odor: waxy, mandarin orange Use: Useful as a topnote to achieve a mandarine-orange, waxy effect. Flavor: Fatty, waxy, citrus peel notes with cilantro and similar types of herbal notes Citrus flavors, specifically orange and tangerine. Excellent for cilantro and similar herbal type flavors. Can be used to impart fatty notes of melon & cucumber. |
| BOC Sciences |
| For experimental / research use only. |
| 2-DODECENAL (HIGH TRANS) FCC 95.0% (sum of isomers) |
| Parchem |
| 2-dodecen-1-al |
| Penta International |
| TRANS-2-DODECEN-1-AL NATURAL NEAT |
Safety Information:
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
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R 38 - Irritating to skin. S 02 - Keep out of the reach of children. S 24 - Avoid contact with skin. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-rat LD50 > 5000 mg/kg oral-rat LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 21, Pg. 849, 1983. | |
| Dermal Toxicity: | |
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skin-rabbit LD50 5000 mg/kg Food and Chemical Toxicology. Vol. 21, Pg. 849, 1983. skin-rabbit LDLo 5000 mg/kg Food and Chemical Toxicology. Vol. 21, Pg. 849, 1983. | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavor and fragrance agents | ||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for 2-dodecenal usage levels up to: | |||
| 1.0000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 1.20 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 2.00 (μg/capita/day) | ||
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 1100 (μg/person/day) | ||
| Threshold of Concern: | 1800 (μg/person/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 2.80000 | |
| beverages(nonalcoholic): | - | 2.90000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 3.10000 | |
| fruit ices: | - | 3.10000 | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 2.80000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). | |||
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. | |||
| average usage mg/kg | maximum usage mg/kg | ||
| Dairy products, excluding products of category 02.0 (01.0): | 3.29000 | 5.83000 | |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | - | - | |
| Edible ices, including sherbet and sorbet (03.0): | - | - | |
| Processed fruit (04.1): | - | - | |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - | |
| Confectionery (05.0): | 2.63000 | 4.75000 | |
| Chewing gum (05.0): | - | - | |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 2.10000 | 4.20000 | |
| Bakery wares (07.0): | 3.20000 | 7.25000 | |
| Meat and meat products, including poultry and game (08.0): | - | - | |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | - | - | |
| Eggs and egg products (10.0): | - | - | |
| Sweeteners, including honey (11.0): | - | - | |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | - | - | |
| Foodstuffs intended for particular nutritional uses (13.0): | - | - | |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 1.81000 | 3.28000 | |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 1.00000 | 3.00000 | |
| Ready-to-eat savouries (15.0): | - | - | |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | - | - | |
Safety References:
| Flavor & Extract Manufacturers Association (FEMA) reference(s): | |
| The FEMA GRAS assessment of alpha,beta-unsaturated aldehydes and related substances used as flavor ingredients. View pdf | |
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 200, Revision 1 (FGE.200 Rev.1): 74 a,ß-unsaturated aliphatic aldehydes and precursors from chemical subgroup 1.1.1 of FGE.19 View page or View pdf | |
| Safety and efficacy of 26 compounds belonging to chemical group 3 (a,ß-unsaturated straight-chain and branched-chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 71 Revision 1 (FGE.71Rev1): consideration of aliphatic, linear, a,ß-unsaturated alcohols, aldehydes, carboxylic acids, and related esters evaluated by JECFA (63rd and 69th meeting) structurally related to flavouring substances evaluated in FGE.05Rev3 View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 4826-62-4 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 20967 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| dodec-2-enal | |
| Chemidplus: | 0004826624 |
References:
| dodec-2-enal | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 4826-62-4 |
| Pubchem (cid): | 20967 |
| Pubchem (sid): | 134984196 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB31020 |
| FooDB: | FDB003013 |
| Export Tariff Code: | 2912.19.9000 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
Potential Uses:
| balsam | FR | |
| citrus | FR | |
| herbal | FR |
Occurrence (nature, food, other): note
| grapefruit oil c.p. @ 0.02% Data GC Search Trop Picture | |
| grapefruit oil c.p. @ 0.03% Data GC Search Trop Picture | |
| grapefruit oil c.p. italy @ trace% Data GC Search Trop Picture | |
| lemon petiole Search Trop Picture |
Synonyms:
| dodec-2-en-1-al | |
| dodec-2-enal | |
| 2- | dodecen-1-al |
| 2- | dodecenal (high trans) |
| 3- | nonyl acrolein |
| beta- | octyl acrolein |