|
Category: flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 0.81500 to 0.81700 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 6.782 to 6.798
|
| Refractive Index: | 1.41400 to 1.41700 @ 20.00 °C.
|
| Melting Point: | -16.00 to -15.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 173.00 to 175.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 94.00 to 95.00 °C. @ 50.00 mm Hg
|
| Acid Value: | 1.00 max. KOH/g
|
| Vapor Pressure: | 1.725000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 4.4 ( Air = 1 ) |
| Flash Point: | 145.00 °F. TCC ( 62.78 °C. )
|
| logP (o/w): | 2.370 |
| Soluble in: |
| | alcohol | | | water, 900 mg/L @ 20 °C (exp) |
Organoleptic Properties:
| |
| Odor Type: earthy |
| |
| Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
| |
| Substantivity: | > 4 hour(s) at 100.00 % |
| |
| | earthy weedy natural woody herbal |
Odor Description: at 10.00 % in dipropylene glycol. | earthy weedy natural woody herbal |
| |
| | musty ketonic cheesy bleu cheese cheesy parmesan cheese earthy dairy |
Odor Description:
| Musty, ketonic, bleu and parmesan cheese-like with earthy and dairy nuances Mosciano, Gerard P&F 21, No. 1, 33, (1996) |
| |
| |
| Flavor Type: dairy |
| |
| | dairy waxy cheesy woody mushroom yeasty |
Taste Description: at 10.00 ppm. | Dairy, waxy, cheese, woody, mushroom and yeast Mosciano, Gerard P&F 21, No. 1, 33, (1996) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| Bedoukian Research |
| METHYL HEXYL KETONE ≥97.5%, FCC, Kosher |
| Odor Description: | sweet, earthy, weedy, 'natural' An interesting note for lilac compositions. |
| Taste Description: | Ketonic, fermented notes Adds ketonic notes for a variety of cheese flavors, unroasted nuts especially hazelnut and cashews. |
| |
| Moellhausen |
| 2-OCTANONE |
| Odor Description: | floral, green, herbaceous, fruity |
| Taste Description: | cheesy, sharp, ketonic (waxy note) |
| |
| Firmenich |
| 2-OCTANONE min. 98%, Kosher for flavor |
| Taste Description: | Intense blue cheese, fruity, mushroom and green notes 2-OCTANONE adds nice fruity, blue and parmesan cheese-like notes with mushroom and dairy nuances to dairy, fruit and cooked meat flavors. |
| |
| PerfumersWorld |
| Methyl hexyl ketone |
| Odor Description: | sweet earthy weedy natural woody herbal green fruity wine floral green herbaceous fruity Blends-well-with - +2-heptanone Herbaceous-notes |
| |
| Nagar Haveli Perfumes & Aromatics |
| Methyl Hexyl Ketone Natural |
| Odor Description: | Musty, ketonic, bleu and parmesan cheese-like with earthy and dairy nuances |
| |
| |
Cosmetic Information:
Suppliers:
| Advanced Biotech |
| 2-OCTANONE NATURAL
98% min. Odor: Camphor, Bitter |
| Alfrebro |
| METHYL HEXYL KETONE NATURAL
Odor: Floral, Green, Herbaceous, Fruity |
| Associate Allied Chemicals |
| Methyl Hexyl Ketone
|
| About |
| Augustus Oils |
| Methyl Hexyl Ketone
|
| Services |
| Aurochemicals |
| 2-OCTANONE, Natural
|
| Axxence Aromatic |
| METHYL HEXYL KETONE Natural
Kosher |
| Sustainability |
| Bedoukian Research |
| METHYL HEXYL KETONE
≥97.5%, FCC, Kosher Odor: sweet, earthy, weedy, 'natural' Use: An interesting note for lilac compositions. Flavor: Ketonic, fermented notes Adds ketonic notes for a variety of cheese flavors, unroasted nuts especially hazelnut and cashews. |
| Berjé |
| Methyl Hexyl Ketone
|
| Media |
| BOC Sciences |
| For experimental / research use only. |
| METHYL HEXYL KETONE FCC 97.5%
|
| CJ Latta & Associates |
| 2-OCTANONE
|
| Diffusions Aromatiques |
| 2-OCTANONE
|
| Diffusions Aromatiques |
| 2-OCTANONE
|
| Ernesto Ventós |
| METHYL HEXYL KETONE
Odor: GREEN,CAMPHOR,LAVENDER,FATTY |
| Excellentia International |
| Methyl Hexyl Ketone (2-Octanone) Natural
|
| Firmenich |
| 2-OCTANONE min. 98%, Kosher
for flavor Flavor: Intense blue cheese, fruity, mushroom and green notes 2-OCTANONE adds nice fruity, blue and parmesan cheese-like notes with mushroom and dairy nuances to dairy, fruit and cooked meat flavors. |
| fnfsurplus.com |
| 2-Octanone
|
| Global Essence |
| Methyl hexyl ketone
|
| Indukern F&F |
| METHYL HEXYL KETONE ( LAVENTERRE )
Odor: FRUITY, EARTHY, MUSHROOM |
| Indukern F&F |
| METHYL HEXYL KETONE
Odor: GREEN, HERBAL, FRUITY |
| Inoue Perfumery |
| HEXYL METHYL KETONE
|
| Kingchem Laboratories |
| 2 OCTANONE
|
| Lluch Essence |
| METHYL HEXYL KETONE NATURAL
|
| Lluch Essence |
| METHYL HEXYL KETONE
|
| M&U International |
| -METHYL HEXYL KETONE, Kosher
|
| Moellhausen |
| 2-OCTANONE
Odor: floral, green, herbaceous, fruity Flavor: cheesy, sharp, ketonic (waxy note) |
| Nagar Haveli Perfumes & Aromatics |
| Methyl Hexyl Ketone
Natural Odor: Musty, ketonic, bleu and parmesan cheese-like with earthy and dairy nuances |
| Odowell Co.,ltd |
| Methyl hexyl ketone
PURITY: 99%min. |
| Penta International |
| METHYL HEXYL KETONE NATURAL
|
| Penta International |
| METHYL HEXYL KETONE PURE
|
| PerfumersWorld |
| Methyl hexyl ketone
Odor: sweet earthy weedy natural woody herbal green fruity wine floral green herbaceous fruity Use: Blends-well-with - +2-heptanone Herbaceous-notes |
| R C Treatt & Co Ltd |
| 2-Octanone
|
| Reincke & Fichtner |
| 2-Octanone
|
| Seqens |
| Methyl Hexyl Ketone, Kosher
|
| Sigma-Aldrich |
| 2-Octanone, ≥98%, FG
Odor: green; herbaceous; floral; fruity |
| Certified Food Grade Products |
| Sigma-Aldrich |
| 2-Octanone, natural, 98%, FG
|
| SRS Aromatics |
| METHYL HEXYL KETONE (FG)
|
| SRS Aromatics |
| METHYL HEXYL KETONE
|
| Synerzine |
| 2-Octanone
|
| Taytonn ASCC |
| Ketone C-8
Odor: Bitter, Floral, Fruity, Green, Herbal/ Herbaceous, Musk/ Musky |
| TCI AMERICA |
| For experimental / research use only. |
| 2-Octanone >98.0%(GC)
|
| The John D. Walsh Company |
| Methyl Hexyl Ketone
|
| The Lermond Company |
| METHYL HEXYL KETONE
|
| The Perfumers Apprentice |
| Methyl Hexyl Ketone
Odor: earthy weedy woody herbal |
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 21 - Harmful in contact with skin. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 20/21 - When using do not eat, drink or smoke. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Human Experience: |
| 4 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg (Katz et al., 1980)
oral-mouse LD50 [sex: M] 3823 mg/kg (Tanii et al., 1986)
oral-mouse LD50 3870 mg/kg (Tanii et al., 1986)
intraperitoneal-mouse LD50 800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4765, 1982.
oral-mouse LD50 3824 mg/kg Toxicology Letters. Vol. 30, Pg. 13, 1986.
unreported-mouse LD50 1600 mg/kg Journal of Medicinal Chemistry. Vol. 19, Pg. 1257, 1976.
intraperitoneal-rat LD50 800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4765, 1982.
oral-rat LD50 3089 mg/kg Kodak Company Reports. Vol. #901875
|
| Dermal Toxicity: |
skin-rabbit LD50 1337 mg/kg Kodak Company Reports. Vol. #901875
|
| Inhalation Toxicity: |
inhalation-rat LC50 2132 ppm/6hours KODAK* #901875
inhalation-rat LC50 > 2132 ppm/6H Kodak Company Reports. Vol. #901875
|
Safety in Use Information:
| Category: | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for 2-octanone usage levels up to: | | | 4.0000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 93.00 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | 0.40000 | 4.00000 |
| beverages(nonalcoholic): | 0.10000 | 1.00000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 0.20000 | 1.00000 |
| fruit ices: | 0.20000 | 1.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | 0.40000 | 4.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 7 (FGE.07): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 View page or View pdf |
Flavouring Group Evaluation 7, Revision 1 (FGE.07Rev1): Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission View page or View pdf |
Flavouring Group Evaluation 7, Revision 2 (FGE.07Rev2) : Saturated and unsaturated aliphatic secondary alcohols, ketones and esters of secondary alcohols and saturated linear or branched-chain carboxylic acids from chemical group 5 View page or View pdf |
Safety and efficacy of saturated and unsaturated aliphatic secondary alcohols, ketones and esters with esters containing secondary alcohols belonging to chemical group 5 when used as flavourings for all animal species View page or View pdf |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 111-13-7 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 8093 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 1224 |
| WGK Germany: | 1 |
| | octan-2-one |
| Chemidplus: | 0000111137 |
| RTECS: | RH1484000 for cas# 111-13-7 |
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| acidic |
| acidic |
| iso | butyric acid | FL/FR |
| | cyclohexyl acetic acid | FL/FR |
| 2- | methyl butyric acid | FL/FR |
| aldehydic |
| | acetyl nonyryl | FL/FR |
| amber |
| | angelica archangelica root oil CO2 extract | FL/FR |
| 1-oxa | spiro-4,7-dodecane | FR |
| balsamic |
| dextro,laevo-iso | borneol | FL/FR |
| iso | bornyl propionate | FL/FR |
| | cedar forest fragrance | FR |
| | conifer acetate | FR |
| buttery |
| | acetyl propionyl | FL/FR |
| | butyl butyryl lactate | FL/FR |
| 2,3- | heptane dione | FL/FR |
| camphoreous |
| dextro- | camphor | FL/FR |
| cheesy |
| | butyric acid | FL/FR |
| | heptanoic acid | FL/FR |
| 2- | methyl hexanoic acid | FL/FR |
| S-( | methyl thio) butyrate | FL/FR |
| 2- | methyl valeric acid | FL/FR |
| 2- | methyl-2-hexenoic acid | FR |
| citrus |
| | neroli ketone | FR |
| | hexanoic acid | FL/FR |
| floral |
| | aglaia odorata absolute | FR |
| | bigarade oxide | FR |
| | ho leaf oil | FR |
| | karo karounde absolute | FR |
| | karo karounde absolute replacer | FR |
| | petitgrain bigarade oil | FL/FR |
| | sambucus nigra flower oil CO2 extract | FR |
| 5- | tricyclodecenyl acetate | FR |
| fruity |
| 3- | benzyl-4-heptanone | FL/FR |
| | cyclohexyl carboxylic acid | FL/FR |
| | filbert hexenone | FL/FR |
| 4- | heptanone | FL/FR |
| | methyl 4-methyl valerate | FL/FR |
| 2- | methyl butyl isovalerate | FL/FR |
| 2- | nonanone | FL/FR |
| | prenyl hexanoate | FL/FR |
| | sorbyl butyrate | FL/FR |
| fungal |
| 1- | decen-3-ol | FL/FR |
| green |
| iso | cyclocitral (IFF) | FL/FR |
| | dicyclopentadiene propionate | FR |
| | fragaria vesca leaf absolute | FR |
| | galbascone (IFF) | FR |
| (E)-2- | hexenal | FL/FR |
| alpha- | hexyl cinnamaldehyde dimethyl acetal | FR |
| para- | methyl hydratropaldehyde | FL/FR |
| hay |
| | tobacco leaf absolute | FL/FR |
| herbal |
| 1- | allyl-2,2,7,7-tetramethyl cycloheptanol | FR |
| | angelica archangelica seed extract | FL/FR |
| | artemisia vestita wall. leaf oil | FR |
| | bornyl 2-methyl butyrate | FL/FR |
| | bornyl butyrate | FL/FR |
| beta- | bourbonene | FL/FR |
| | calamintha clinopodium oil | FR |
| | cardamom liquid resin | FR |
| | dill seed oil | FL/FR |
| | dill seed oil CO2 extract | FL/FR |
| | herbal ketone | FR |
| | herbal undecanone | FR |
| | immortelle flower oil | FL/FR |
| | lavandin water absolute | FL/FR |
| 2- | methyl butyl salicylate | FL/FR |
| 1- | octen-3-yl acetate | FL/FR |
| alpha- | pinene | FL/FR |
| | pinocarveol | FL/FR |
| | thyme oil wild or creeping | FL/FR |
| minty |
| | nepeta cataria herb oil | FR |
| | pennyroyal oil | FL/FR |
| musk |
| | angelica root absolute | FL/FR |
| nutty |
| | nutty quinoxaline | FL/FR |
| | pentanoic acid, 3-methyl-2-oxo-, ethyl ester | FL/FR |
| oily |
| | butter acids | FL/FR |
| orris |
| para-iso | propyl acetophenone | FL/FR |
| spicy |
| | bayberry fragrance | FR |
| | cardamom seed oil CO2 extract | FL/FR |
| | cinnamon acrolein | FL/FR |
| | ginger oleoresin africa | FL/FR |
| | ginger root absolute | FL/FR |
| | ginger root oil cochin | FL/FR |
| | maja fragrance | FR |
| | myrcene | FR |
| 2- | octanol | FL/FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| white | pepper oil | FL/FR |
| black | pepper oleoresin | FL/FR |
| 4-iso | propyl-2-cyclohexenone | FL/FR |
| thujonic |
| | cedarleaf oil western red | FR |
| common | tansy flower oil argentina | FL/FR |
| common | tansy leaf oil dutch | FR |
| | woody ketone | FL/FR |
| waxy |
| 5(6)- | decenoic acid | FL/FR |
| 2- | methyl heptanoic acid | FL/FR |
| | nonanoic acid | FL/FR |
| 2- | nonanol | FL/FR |
| | undecanoic acid | FL/FR |
| woody |
| | angelica archangelica root extract | FL/FR |
| | angelica archangelica root tincture | FL/FR |
| | angelica archangelica root water | FL/FR |
| | cadinene | FL/FR |
| (+)- | camphene | FL/FR |
| | camphene | FL/FR |
| | cypress essence | FR |
| | dalbergia sissoo leaf oil | FR |
| | dihydro-alpha-terpinyl acetate | FR |
| | fougere woody fragrance | FR |
| (1R,4S)-1- | hydroxy-1,4-dimethyl spiro(4.6)undecan-2-one | |
| | laitone | FR |
| | manevoro oil | FR |
| | marine formate | FR |
| | melaleuca bracteata leaf oil | FR |
| gamma- | muurolene | |
| | origanum vulgare ssp. vulgare oil himalaya | |
| | patchouli fragrance | FR |
| | patchouli oil | FL/FR |
| | patchouli oil CO2 extract | FL/FR |
| | patchouli oil decolorized | FL/FR |
| | patchouli oil molecular distilled | FL/FR |
| | patchouli oil replacer | FR |
| | patchouli specialty | FR |
| | polylimonene | FL/FR |
| | santol pentenol | FR |
| | tetrahydromugol | FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | angelica archangelica root extract | FL/FR |
| | angelica archangelica root oil CO2 extract | FL/FR |
| | angelica archangelica root tincture | FL/FR |
| | angelica archangelica root water | FL/FR |
| | bornyl 2-methyl butyrate | FL/FR |
| | bornyl butyrate | FL/FR |
| beta- | bourbonene | FL/FR |
| delta- | cadinene | FL |
| (+)- | camphene | FL/FR |
| | ethyl cyclohexyl carboxylate | FL |
| (E,E)-2,4- | heptadien-1-ol | FL |
| (Z)-3- | hexenoic acid | FL |
| (1R,4S)-1- | hydroxy-1,4-dimethyl spiro(4.6)undecan-2-one | |
| 2- | methyl butyl salicylate | FL/FR |
| 5- | methyl hexanoic acid | FL |
| 1- | methyl pyrrole | FL |
| 4- | methyl valeric acid | FL |
| gamma- | muurolene | |
| | origanum vulgare ssp. vulgare oil himalaya | |
| | polylimonene | FL/FR |
| | prenyl hexanoate | FL/FR |
| 4-iso | propyl-2-cyclohexenone | FL/FR |
| | woody ketone | FL/FR |
| acidic |
| iso | butyric acid | FL/FR |
| aldehydic |
| | acetyl nonyryl | FL/FR |
| balsamic |
| iso | bornyl propionate | FL/FR |
| buttery |
| | butter crème flavor | FL |
| creamy | butter flavor | FL |
| 2,3- | heptane dione | FL/FR |
| 2- | methyl valeric acid | FL/FR |
| (E)-2- | pentenoic acid | FL |
| camphoreous |
| dextro,laevo-iso | borneol | FL/FR |
| | camphene | FL/FR |
| | pinocarveol | FL/FR |
| | hexanoic acid | FL/FR |
| 2- | nonanone | FL/FR |
| citrus |
| | petitgrain bigarade oil | FL/FR |
| creamy |
| | acetoin butyrate | FL |
| | butyl butyryl lactate | FL/FR |
| 5(6)- | decenoic acid | FL/FR |
| 2- | methyl-4-pentenoic acid | FL |
| dairy |
| 4- | pentenoic acid | FL |
| earthy |
| 1- | decen-3-ol | FL/FR |
| fatty |
| | butter acids | FL/FR |
| | nonanoic acid | FL/FR |
| (E)-2- | octenoic acid | FL |
| fermented |
| | methyl thio isovalerate | FL |
| fruity |
| 3- | benzyl-4-heptanone | FL/FR |
| | cyclohexyl carboxylic acid | FL/FR |
| | filbert hexenone | FL/FR |
| 4- | heptanone | FL/FR |
| | methyl 4-methyl valerate | FL/FR |
| 2- | methyl butyl isovalerate | FL/FR |
| 2- | methyl butyric acid | FL/FR |
| | sorbyl butyrate | FL/FR |
| grassy |
| | tobacco leaf absolute | FL/FR |
| green |
| iso | cyclocitral (IFF) | FL/FR |
| (E)-2- | hexenal | FL/FR |
| para- | methyl hydratropaldehyde | FL/FR |
| 1- | octen-3-yl acetate | FL/FR |
| herbal |
| | angelica archangelica seed extract | FL/FR |
| | dill seed oil | FL/FR |
| | dill seed oil CO2 extract | FL/FR |
| | immortelle flower oil | FL/FR |
| | lavandin water absolute | FL/FR |
| | thyme oil wild or creeping | FL/FR |
| meaty |
| 2- | methyl 3-(methyl thio) furan | FL |
| medicinal |
| dextro- | camphor | FL/FR |
| minty |
| | pennyroyal oil | FL/FR |
| musk |
| | angelica root absolute | FL/FR |
| musty |
| S-( | methyl thio) butyrate | FL/FR |
| nutty |
| | nutty quinoxaline | FL/FR |
| | pentanoic acid, 3-methyl-2-oxo-, ethyl ester | FL/FR |
| oily |
| 2- | methyl hexanoic acid | FL/FR |
| sour |
| | butyric acid | FL/FR |
| 2,4- | dimethyl-2-pentenoic acid | FL |
| 3- | methyl valeric acid | FL |
| spicy |
| | cardamom seed oil CO2 extract | FL/FR |
| | cinnamon acrolein | FL/FR |
| | ginger oleoresin africa | FL/FR |
| | ginger root absolute | FL/FR |
| | ginger root oil cochin | FL/FR |
| 2- | octanol | FL/FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| white | pepper oil | FL/FR |
| black | pepper oleoresin | FL/FR |
| para-iso | propyl acetophenone | FL/FR |
| sulfurous |
| | methyl 4-(methyl thio) butyrate | FL |
| sweet |
| | cyclohexyl acetic acid | FL/FR |
| thujonic |
| common | tansy flower oil argentina | FL/FR |
| toasted |
| | acetyl propionyl | FL/FR |
| waxy |
| | heptanoic acid | FL/FR |
| 2- | methyl heptanoic acid | FL/FR |
| 2- | nonanol | FL/FR |
| | undecanoic acid | FL/FR |
| woody |
| | cadinene | FL/FR |
| | patchouli oil | FL/FR |
| | patchouli oil CO2 extract | FL/FR |
| | patchouli oil decolorized | FL/FR |
| | patchouli oil molecular distilled | FL/FR |
| alpha- | pinene | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | hexyl methyl ketone | | N- | hexyl methyl ketone | | | ketone, hexyl methyl | | | laventerre | | | methyl hexyl cetone | | | methyl hexyl ketone | | | methyl hexyl ketone 90 | | | methyl hexyl ketone, natural | | | methyl N-hexyl ketone | | | octan-2-one | | 2-oxo | octane | | | octane-2-one | | 2- | octanon | | 2- | octanone | | 2- | octanone natural |
Articles:
| US Patents: | 3,952,024 - Furfurylthioacetone |
| PubMed: | Binding of carbonyl flavours to canola, pea and wheat proteins using GC/MS approach. |
| US Patents: | 3,931,166 - Certain 2,5-dimethyl-3-thiopyrazines |
| PubMed: | Communication: Coordination structure of bromide ions associated with hexyltrimethylammonium cations at liquid/liquid interfaces under potentiostatic control as studied by total-reflection X-ray absorption fine structure. |
| PubMed: | Olfactory Sensitivity and Odor Structure-Activity Relationships for Aliphatic Ketones in CD-1 Mice. |
| PubMed: | Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose. |
| PubMed: | Brushed block copolymer micelles with pH-sensitive pendant groups for controlled drug delivery. |
| PubMed: | Mass and Ion Transport in Ketones and Ketone Electrolytes: Comparison with Acetate Systems. |
| PubMed: | Formation yields of C8 1,4-hydroxycarbonyls from OH + n-octane in the presence of NO. |
| PubMed: | Brain phospholipase C, diacylglycerol lipase and monoacylglycerol lipase are involved in (±)-epibatidine-induced activation of central adrenomedullary outflow in rats. |
| PubMed: | Analysis of quinolones by voltage-assisted liquid-phase microextraction combined with LC-MS. |
| PubMed: | Fragrance material review on methyl hexyl oxo cyclopentanone carboxylate. |
| PubMed: | Color, lipid oxidation, sensory quality, and aroma compounds of beef steaks displayed under different levels of oxygen in a modified atmosphere package. |
| PubMed: | Electromembrane extraction of peptides--fundamental studies on the supported liquid membrane. |
| PubMed: | Evaluation of parallel milliliter-scale stirred-tank bioreactors for the study of biphasic whole-cell biocatalysis with ionic liquids. |
| PubMed: | Evaluation of the use of Syzygium cumini fruit extract as an antioxidant additive in orange juice and its sensorial impact. |
| PubMed: | Controlling the facial selectivity of asymmetric [4+2] cyclo-additions: a concise synthesis of the cis-decalin core structure of superstolides A and B. |
| PubMed: | Thermodynamics and activity coefficients at infinite dilution measurements for organic solutes and water in the ionic liquid N-hexyl-3-methylpyridinium tosylate. |
| PubMed: | Comparison of volatile components in Chinese traditional pickled peppers using HS-SPME-GC-MS, GC-O and multivariate analysis. |
| PubMed: | Solvent free oxidation of primary alcohols and diols using thymine iron(III) catalyst. |
| PubMed: | Novel aspect of ketone action: β-hydroxybutyrate increases brain synthesis of kynurenic acid in vitro. |
| PubMed: | Isolation and characterization of 4-tert-butylphenol-utilizing Sphingobium fuliginis strains from Phragmites australis rhizosphere sediment. |
| PubMed: | Neurotoxicity of fungal volatile organic compounds in Drosophila melanogaster. |
| PubMed: | Prolonged stimulus exposure reveals prolonged neurobehavioral response patterns. |
| PubMed: | Hollow fiber-liquid-phase microextraction of fungicides from orange juices. |
| PubMed: | Asymmetric [4+2] cycloadditions employing 1,3-dienes derived from (R)-4-t-butyldimethyl-silyloxy-2-cyclohexen-1-one. |
| PubMed: | Purification and characterization of an anti-Prelog alcohol dehydrogenase from Oenococcus oeni that reduces 2-octanone to (R)-2-octanol. |
| PubMed: | Widespread occurrence of estrogenic UV-filters in aquatic ecosystems in Switzerland. |
| PubMed: | Ionic liquid based dispersive liquid-liquid microextraction for the extraction of pesticides from bananas. |
| PubMed: | Gas chromatography-olfactometry analysis of the volatile compounds of two commercial Irish beef meats. |
| PubMed: | Selective three-phase liquid phase microextraction of acidic compounds from foodstuff simulants. |
| PubMed: | Chemical characterization of territorial marking fluid of male Bengal tiger, Panthera tigris. |
| PubMed: | Templation of the excited-state chemistry of alpha-(n-alkyl) dibenzyl ketones: how guest packing within a nanoscale supramolecular capsule influences photochemistry. |
| PubMed: | Optimization of chlorophyllase-catalyzed hydrolysis of chlorophyll in monophasic organic solvent media. |
| PubMed: | Kinetic analysis of volatile formation in milk subjected to pressure-assisted thermal treatments. |
| PubMed: | Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. |
| PubMed: | Purification, characterization, and gene cloning of glycerol dehydrogenase from Hansenula ofunaensis, and its expression for production of optically active diol. |
| PubMed: | Anti-prelog reduction of prochiral carbonyl compounds by Oenococcus oeni in a biphasic system. |
| PubMed: | Chemical boundaries for detection of eye irritation in humans from homologous vapors. |
| PubMed: | Dominant role for calpain in thromboxane-induced neuromicrovascular endothelial cytotoxicity. |
| PubMed: | Stability of immobilized soybean lipoxygenase in selected organic solvent media. |
| PubMed: | Stereoselective synthesis of c3-c12 dihydropyran portion of antitumor laulimalide using copper-catalyzed oxonium ylide formation-[2,3] shift. |
| PubMed: | 1,4-hydroxycarbonyl products of the OH radical initiated reactions of C5-C8 n-alkanes in the presence of NO. |
| PubMed: | Bis{1-n-hexyl-3-methyl-4-[1-(phenylimino)propyl]-1H-pyrazol-5-olato}copper(II): a new copper(II) complex with a chelating alkylpyrazolone-based enamine. |
| PubMed: | Characterization of French and Spanish dry-cured hams: influence of the volatiles from the muscles and the subcutaneous fat quantified by SPME-GC. |
| PubMed: | Designing the "search pathway" in the development of a new class of highly efficient stereoselective hydrosilylation catalysts. |
| PubMed: | High-yield conversion of (R)-2-octanol from the corresponding racemate by stereoinversion using Candida rugosa. |
| PubMed: | Bimetallic isopropoxides M[Al(OC(3)H(i)(7))(4)](3) (M = Pr, Nd)--catalyzed reduction of 2-octanone and benzophenone. |
| PubMed: | Controlled production of Camembert-type cheeses. Part II. Changes in the concentration of the more volatile compounds. |
| PubMed: | Use of an ionic liquid in a two-phase system to improve an alcohol dehydrogenase catalysed reduction. |
| PubMed: | Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. |
| PubMed: | Volatiles in a sausage surface model-influence of Penicillium nalgiovense, Pediococcus pentosaceus, ascorbate, nitrate and temperature. |
| PubMed: | An efficient direct alpha-alkylation of ketones with primary alcohols catalyzed by [Ir(cod)Cl]2/PPh3/KOH system without solvent. |
| PubMed: | Analysis of ketones by selected ion flow tube mass spectrometry. |
| PubMed: | Synthesis of (4R,6S,7R)-7-hydroxy-4,6-dimethyl-3-nonanone and (3R,5S,6R)- 6-hydroxy-3,5-dimethyl-2-octanone, the pheromone components of the bostrychid beetle, Dinoderus bifoveolatus. |
| PubMed: | Associative learning of complex odours in parasitoid host location. |
| PubMed: | Relationship between molecular structure, concentration and odor qualities of oxygenated aliphatic molecules. |
| PubMed: | Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner. |
| PubMed: | Aroma active components in aqueous kiwi fruit essence and kiwi fruit puree by GC-MS and multidimensional GC/GC-O. |
| PubMed: | Influence of lipid fraction, emulsifier fraction, and mean particle diameter of oil-in-water emulsions on the release of 20 aroma compounds. |
| PubMed: | Selective Oxidation of Vinyl Ethers and Silyl Enol Ethers with Hydrogen Peroxide Catalyzed by Peroxotungstophosphate. |
| PubMed: | An enantiospecific approach to tricyclic sesquiterpenes mayurone and thujopsenes. |
| PubMed: | Asymmetric reduction of ketones with catecholborane using 2,6-BODOL complexes of titanium(IV) as catalysts. |
| PubMed: | Interactions between artificial saliva and 20 aroma compounds in water and oil model systems. |
| PubMed: | Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries. |
| PubMed: | Efficient oxidation of alcohols to carbonyl compounds with molecular oxygen catalyzed by N-hydroxyphthalimide combined with a Co species |
| PubMed: | Interactions between methyl ketones and beta-lactoglobulin: sensory analysis, headspace analysis, and mathematical modeling. |
| PubMed: | Blocking and the detection of odor components in blends. |
| PubMed: | Interactions of flavor compounds with pectic substances. |
| PubMed: | Oxidative cleavage of the octyl side chain of 1-(3,4-dichlorobenzyl)-5-octylbiguanide (OPB-2045) in rat and dog liver preparations. |
| PubMed: | Effect of aeration during cell growth on ketone reactions by immobilized yeast. |
| PubMed: | Interactions between aroma and edible films. 1. Permeability Of methylcellulose and low-density polyethylene films to methyl ketones. |
| PubMed: | Solvent-modified solid-phase microextraction for the determination of diazepam in human plasma samples by capillary gas chromatography. |
| PubMed: | An analysis of blocking in odorant mixtures: an increase but not a decrease in intensity of reinforcement produces unblocking. |
| PubMed: | Neighboring Group Participation in a Regio- and Stereoselective Chlorination of a Bicyclo[2.2.2]octanone. |
| PubMed: | Enhanced sensitivity to androstenone following regular exposure to pemenone. |
| PubMed: | Effects of solvation on partition and dimerization of benzoic acid in mixed solvent systems. |
| PubMed: | Ketone EC50 values in the Microtox test. |
| PubMed: | Structure, stereochemistry, and thermal isomerization of the male sex pheromone of the longhorn beetle Anaglyptus subfasciatus. |
| PubMed: | Immiscible organic solvent inactivation of urease, chymotrypsin, lipase, and ribonuclease: separation of dissolved solvent and interfacial effects. |
| PubMed: | Juvenile hormone esterase purified by affinity chromatography with 8-mercapto-1,1,1-trifluoro-2-octanone as a rationally designed ligand. |
| PubMed: | Sensory irritation and pulmonary irritation of n-methyl ketones: receptor activation mechanisms and relationships with threshold limit values. |
| PubMed: | Effect of some metallic cations and organic compounds on the O-hexyl O-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma. |
| PubMed: | Competitive inhibition of lipolytic enzymes. VII. The interaction of pancreatic phospholipase A2 with micellar lipid/water interfaces of competitive inhibitors. |
| PubMed: | Electroantennogram response of alfalfa seed chalcid,Bruchophagus roddi (Hymenoptera: Eurytomidae) to host- and nonhost-plant volatiles. |
| PubMed: | Antidopaminergic effects of the stereoisomers of N-[(1-alkyl-2- pyrrolidinyl)methyl]-5-sulfamoylbenzamides and -2,3-dihydrobenzofuran-7-carboxamides. |
| PubMed: | Inhibition of cathepsin B and papain by peptidyl alpha-keto esters, alpha-keto amides, alpha-diketones, and alpha-keto acids. |
| PubMed: | Volatile methyl ketone seed-germination inhibitors fromAmaranthus palmeri S. Wats. Residues. |
| PubMed: | Experimental study on the enhancement of the neurotoxicity of methyl n-butyl ketone by non-neurotoxic aliphatic monoketones. |
| PubMed: | Neurophysiological studies on the relation between the structural properties and neurotoxicity of aliphatic hydrocarbon compounds in rats. |
| PubMed: | Volatile constituents of wolf (Canis lupus) urine as related to gender and season. |
| PubMed: | Further studies on ketone neurotoxicity and interactions. |
| PubMed: | [An experimental study on the neurotoxicity of 2-octanone and 2-hexanol, a metabolite of n-hexane]. |
| PubMed: | Commercial-grade methyl heptyl ketone (5-methyl-2-octanone) neurotoxicity: contribution of 5-nonanone. |
| PubMed: | Gas-chromatographic resolution of enantiomeric secondary alcohols. Stereoselective reductive metabolism of ketones in rabbit-liver cytosol. |
| PubMed: | Cycloalkanones. 9. Comparison of analogues which inhibit cholesterol and fatty acid synthesis. |
| PubMed: | Cycloalkanones. 7. Hypocholesterolemic activity of aliphatic compounds related to 2,8-dibenzylcyclooctanone. |
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