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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear slightly viscous liquid (est) |
| Assay: | 98.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.97900 to 0.98700 @ 20.00 °C.
|
| Pounds per Gallon - est.: | 8.156 to 8.222
|
| Boiling Point: | 409.00 to 410.00 °C. @ 760.00 mm Hg
|
| Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
|
| logP (o/w): | 3.642 (est) |
| Soluble in: |
| | alcohol | | | water, 1.433 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
| Stability: |
| | detergent | | | soap |
Organoleptic Properties:
| |
| Odor Type: musk |
| |
| Odor Strength: | medium |
| |
| Substantivity: | 92 hour(s) at 100.00 % |
| |
| | musk woody sweet waxy fruity |
Odor Description: at 100.00 %. | musk woody sweet brassylate fruity Luebke, William tgsc, (1984) |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| Givaudan |
| Cervolide |
| Odor Description: | Musky, Powdery Cervolide has a fine musk note, slightly fruity with a woody background. |
| |
| |
Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| 1,6-Dioxacycloheptadecan-7-one
|
| Diffusions Aromatiques |
| 12 OXAHEXADECANOLIDE
|
| Ernesto Ventós |
| MUSK 781 (CERVOLIDE)
Odor: SWEET,TENACIOUS,FRUITY MUSK,CLEAN |
| Givaudan |
| Cervolide
Odor: Musky, Powdery Use: Cervolide has a fine musk note, slightly fruity with a woody background. |
| Keva |
| 12-OHD
Odor: Musk, woody, sweet, fruity |
| Lluch Essence |
| CERVOLIDE
|
| Moellhausen |
| MUSK 174
|
| Penta International |
| 12-OXAHEXADECANOLIDE
|
| SRS Aromatics |
| 12-OXAHEXADECANOLIDE
Odor: Musk, Woody, Sweet, Brassylate, Fruity |
| The John D. Walsh Company |
| Cervolide
|
| Vigon International |
| Cervolide (12-oxa Hexadecanolide)
Odor: Musky, Powdery |
Safety Information:
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 789, 1982.
|
| Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 789, 1982.
|
| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
Safety References:
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| aldehydic |
| | citrus carbaldehyde | FR |
| | decanal (aldehyde C-10) | FL/FR |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| 2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
| | nonanal (aldehyde C-9) | FL/FR |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| amber |
| | amber naphthofuran | FL/FR |
| | amber oxepin | FR |
| | ambrette seed absolute | FL/FR |
| | ambrette seed oil | FL/FR |
| | ambroxan | FL/FR |
| | ambroxide | FL/FR |
| | angelica root oil | FL/FR |
| | cistus ladaniferus resinoid | FL/FR |
| (cis+trans)-6,6a,7,8,9,9a- | hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| animal |
| | musk indenofuran | FR |
| anise |
| sweet | fennel seed oil | FL/FR |
| anisic |
| para- | anisaldehyde | FL/FR |
| balsamic |
| iso | amyl benzoate | FL/FR |
| | amyris wood oil | FL/FR |
| siam | benzoin resinoid | FL/FR |
| | benzophenone | FR |
| | benzyl benzoate | FL/FR |
| | benzyl cinnamate | FL/FR |
| | benzyl salicylate | FL/FR |
| laevo- | borneol | FL/FR |
| iso | bornyl acetate | FL/FR |
| laevo- | bornyl acetate | FL/FR |
| | brachyleana hutchinsii wood oil | FR |
| iso | butyl cinnamate | FL/FR |
| | cinnamyl alcohol | FL/FR |
| | clover nitrile | FR |
| | ethyl cinnamate | FL/FR |
| | fir balsam absolute | FR |
| | methyl (E)-cinnamate | FL/FR |
| | myrrh oil | FL/FR |
| | opoponax resinoid replacer | FR |
| | oriental specialty | FR |
| | peru balsam oil | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| | phenyl salicylate | FR |
| | valerian rhizome absolute | FL/FR |
| berry |
| | raspberry ketone | FL/FR |
| | raspberry ketone acetate | FL/FR |
| | raspberry ketone methyl ether | FL/FR |
| caramellic |
| | ethyl maltol | FL/FR |
| chemical |
| iso | butyl formate | FL/FR |
| chocolate |
| iso | amyl phenyl acetate | FL/FR |
| citrus |
| blood | orange oil italy | FL/FR |
| coconut |
| gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| gamma- | octalactone | FL/FR |
| earthy |
| (Z)- | linalool oxide (furanoid) | FL/FR |
| floral |
| alpha- | amyl cinnamaldehyde | FL/FR |
| iso | amyl salicylate | FL/FR |
| | bois de rose oil brazil | FL/FR |
| | citronellol | FL/FR |
| | coriander seed oil | FL/FR |
| | cyclamen aldehyde | FL/FR |
| | cyclohexyl ethyl alcohol | FL/FR |
| | dimethyl anthranilate | FL/FR |
| | dimethyl benzyl carbinol | FL/FR |
| | dimethyl benzyl carbinyl butyrate | FL/FR |
| | ethyl phenyl acetate | FL/FR |
| | floral pyranol | FR |
| | gardenia oxide | FR |
| | geraniol | FL/FR |
| | heliotropin | FL/FR |
| | heliotropyl acetone | FL/FR |
| | heliotropyl diethyl acetal | FR |
| (Z)-3- | hexen-1-yl salicylate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | hyacinth ether | FR |
| | hydroxycitronellal | FL/FR |
| beta- | ionone | FL/FR |
| | leerall | FR |
| | lilyall | FR |
| | linalool | FL/FR |
| laevo- | linalool | FL/FR |
| | linalool oxide | FL/FR |
| | methyl dihydrojasmonate | FL/FR |
| 2- | methyl naphthalene | FL/FR |
| | mimosa absolute france | FL/FR |
| | muguet octadienol | FR |
| | nonanol | FL/FR |
| | ocean propanal | FL/FR |
| bitter | orangeflower concrete morocco | FR |
| | orris pyridine 25% IPM | FR |
| | peony alcohol | FR |
| | phenethyl acetate | FL/FR |
| | phenethyl alcohol | FL/FR |
| | phenethyl phenyl acetate | FL/FR |
| | rhodinol | FL/FR |
| | rose butanoate | FL/FR |
| | rose undecene | FR |
| | tea acetate | FR |
| | tetrahydrolinalool | FL/FR |
| | tuberose acetate | FR |
| | violet methyl carbonate | FR |
| fruity |
| | allyl amyl glycolate | FR |
| | allyl cyclohexyl propionate | FL/FR |
| | amyl hexanoate | FL/FR |
| iso | amyl hexanoate | FL/FR |
| | artemisia pallens herb oil | FL/FR |
| | cyclohexyl crotonate | FR |
| (E)-beta- | damascone | FL/FR |
| (E)-alpha- | damascone | FL/FR |
| (R)-gamma- | dodecalactone | FL/FR |
| | menthyl isovalerate | FL/FR |
| 2- | nonanone | FL/FR |
| iso | octyl acetate | FR |
| | osmanthus flower absolute | FL/FR |
| iso | propenyl acetate | FL/FR |
| | propyl butyrate | FL/FR |
| | tropical indene | FR |
| gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| green |
| | acetaldehyde benzyl 2-methoxyethyl acetal | FL/FR |
| | green carboxylate | FR |
| iso | green methanoindene | FR |
| (Z)-3- | hexen-1-yl acetate | FL/FR |
| 3- | hexenyl 2-methyl butyrate | FL/FR |
| | hexoxyacetaldehyde dimethyl acetal | FR |
| (Z)- | leaf acetal | FL/FR |
| | melon nonenoate | FL/FR |
| | methyl heptine carbonate | FL/FR |
| | methyl octine carbonate | FL/FR |
| 3- | phenyl propionaldehyde | FL/FR |
| | rose leaf absolute (rosa centifolia) | FL/FR |
| | violet leaf absolute | FL/FR |
| hay |
| | hay absolute | FR |
| | tobacco leaf absolute | FL/FR |
| herbal |
| | carum carvi fruit oil | FL/FR |
| | clary sage oil france | FL/FR |
| | daucus carota fruit oil | FL/FR |
| delta- | elemene | FL/FR |
| | lavender absolute bulgaria | FL/FR |
| | linalyl acetate | FL/FR |
| | marigold oil mexico | FL/FR |
| | tea leaf absolute | FL/FR |
| honey |
| | phenyl acetic acid | FL/FR |
| mentholic |
| iso | pulegyl acetate | FL/FR |
| mossy |
| | oakmoss absolute | FL/FR |
| | veramoss (IFF) | FR |
| musk |
| | acetyl ethyl tetramethyl tetralin replacer | FR |
| | musk indanone | FR |
| musty |
| ketoiso | phorone | FL/FR |
| naphthyl |
| beta- | naphthyl ethyl ether | FL/FR |
| powdery |
| para- | anisyl acetate | FL/FR |
| para- | anisyl alcohol | FL/FR |
| spicy |
| | allspice oil | FL/FR |
| | benzyl isoeugenol | FL/FR |
| | cassia bark oil china | FL/FR |
| | clove bud oil | FL/FR |
| black | currant bud absolute | FL/FR |
| 2,5- | dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate + 1,4-dimethyl bicyclo(3.2.1)-2-octen-3-yl acetate | FR |
| iso | eugenyl acetate | FL/FR |
| | ginger root absolute | FL/FR |
| | grains of paradise oil | FL/FR |
| | methyl heptadienone | FL/FR |
| | methyl isoeugenol | FL/FR |
| | nutmeg oil | FL/FR |
| black | pepper oil | FL/FR |
| | pimenta acris leaf oil | FL/FR |
| terpenic |
| | frankincense oil | FL/FR |
| alpha- | terpineol | FL/FR |
| thujonic |
| | armoise oil | FR |
| tonka |
| | coumarin | FR |
| | tonka bean absolute | FR |
| vanilla |
| | ethyl vanillin | FL/FR |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| | vanilla oleoresin bourbon | FL/FR |
| | vanillyl acetate | FL/FR |
| waxy |
| iso | amyl decanoate | FL/FR |
| 1- | dodecanol | FL/FR |
| | ethyl laurate | FL/FR |
| 1- | undecanol | FL/FR |
| woody |
| | agarwood oil (aetoxylon sympetalum) | FR |
| | cabreuva wood oil | FR |
| | cistus twig/leaf oil | FL/FR |
| | guaiacwood oil | FL/FR |
| | guaiacwood oil 20% in gurjun balsam oil | FR |
| | gurjun balsam oil | FR |
| | homalomena rubescens root oil | FR |
| | methyl cedryl ketone | FL/FR |
| delta- | methyl ionone | FL/FR |
| | patchouli ethanone | FR |
| | patchouli oil | FL/FR |
| | sandal pentenol | FL/FR |
| | sandalwood oil | FL/FR |
| | sandalwood oil CO2 extract | FL/FR |
| | santall | FR |
| | spikenard oil CO2 extract | FL/FR |
| | spruce needle oil canada | FL/FR |
| | tobacarol (IFF) | FR |
| | vetiver oil haiti | FL/FR |
| | woody acetate | FR |
| (Z)- | woody amylene | FR |
| | woody propanol | FR |
| |
| For Flavor |
| |
| No flavor group found for these |
| | acetaldehyde benzyl 2-methoxyethyl acetal | FL/FR |
| | ambroxide | FL/FR |
| | cistus ladaniferus resinoid | FL/FR |
| (R)-gamma- | dodecalactone | FL/FR |
| delta- | elemene | FL/FR |
| | grains of paradise oil | FL/FR |
| (Z)- | linalool oxide (furanoid) | FL/FR |
| | methyl (E)-cinnamate | FL/FR |
| delta- | methyl ionone | FL/FR |
| | sandal pentenol | FL/FR |
| | spikenard oil CO2 extract | FL/FR |
| aldehydic |
| | nonanal (aldehyde C-9) | FL/FR |
| 1- | undecanol | FL/FR |
| amber |
| | amber naphthofuran | FL/FR |
| | ambrette seed oil | FL/FR |
| anise |
| sweet | fennel seed oil | FL/FR |
| balsamic |
| siam | benzoin resinoid | FL/FR |
| | benzyl benzoate | FL/FR |
| | benzyl salicylate | FL/FR |
| laevo- | bornyl acetate | FL/FR |
| iso | butyl cinnamate | FL/FR |
| | ethyl cinnamate | FL/FR |
| | myrrh oil | FL/FR |
| | peru balsam oil | FL/FR |
| berry |
| | heliotropyl acetone | FL/FR |
| | raspberry ketone | FL/FR |
| | raspberry ketone acetate | FL/FR |
| | raspberry ketone methyl ether | FL/FR |
| camphoreous |
| laevo- | borneol | FL/FR |
| caramellic |
| | ethyl maltol | FL/FR |
| cheesy |
| 2- | nonanone | FL/FR |
| cherry |
| | heliotropin | FL/FR |
| citrus |
| laevo- | linalool | FL/FR |
| | linalool | FL/FR |
| blood | orange oil italy | FL/FR |
| ketoiso | phorone | FL/FR |
| alpha- | terpineol | FL/FR |
| coconut |
| gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| creamy |
| para- | anisaldehyde | FL/FR |
| gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| ethereal |
| iso | propenyl acetate | FL/FR |
| fatty |
| 10- | undecenal (aldehyde C-11 undecylenic) | FL/FR |
| floral |
| iso | amyl phenyl acetate | FL/FR |
| | bois de rose oil brazil | FL/FR |
| | citronellol | FL/FR |
| | dimethyl benzyl carbinyl butyrate | FL/FR |
| | geraniol | FL/FR |
| | linalyl acetate | FL/FR |
| | methyl dihydrojasmonate | FL/FR |
| | ocean propanal | FL/FR |
| | phenethyl alcohol | FL/FR |
| | phenyl acetic acid | FL/FR |
| | rhodinol | FL/FR |
| | tetrahydrolinalool | FL/FR |
| fruity |
| | allyl cyclohexyl propionate | FL/FR |
| iso | amyl benzoate | FL/FR |
| iso | amyl hexanoate | FL/FR |
| | amyl hexanoate | FL/FR |
| para- | anisyl acetate | FL/FR |
| para- | anisyl alcohol | FL/FR |
| | artemisia pallens herb oil | FL/FR |
| (E)-beta- | damascone | FL/FR |
| (E)-alpha- | damascone | FL/FR |
| | dimethyl anthranilate | FL/FR |
| | menthyl isovalerate | FL/FR |
| | osmanthus flower absolute | FL/FR |
| | propyl butyrate | FL/FR |
| | rose butanoate | FL/FR |
| | valerian rhizome absolute | FL/FR |
| grassy |
| | tobacco leaf absolute | FL/FR |
| green |
| iso | amyl salicylate | FL/FR |
| | angelica root oil | FL/FR |
| | cinnamyl alcohol | FL/FR |
| | cyclamen aldehyde | FL/FR |
| | cyclohexyl ethyl alcohol | FL/FR |
| (Z)-3- | hexen-1-yl acetate | FL/FR |
| (Z)-3- | hexen-1-yl salicylate | FL/FR |
| 3- | hexenyl 2-methyl butyrate | FL/FR |
| (Z)- | leaf acetal | FL/FR |
| | linalool oxide | FL/FR |
| | melon nonenoate | FL/FR |
| | methyl heptadienone | FL/FR |
| | methyl heptine carbonate | FL/FR |
| | methyl octine carbonate | FL/FR |
| | oakmoss absolute | FL/FR |
| 3- | phenyl propionaldehyde | FL/FR |
| | rose leaf absolute (rosa centifolia) | FL/FR |
| | violet leaf absolute | FL/FR |
| herbal |
| | carum carvi fruit oil | FL/FR |
| | clary sage oil france | FL/FR |
| | coriander seed oil | FL/FR |
| | daucus carota fruit oil | FL/FR |
| | lavender absolute bulgaria | FL/FR |
| | marigold oil mexico | FL/FR |
| honey |
| | ethyl phenyl acetate | FL/FR |
| | phenethyl acetate | FL/FR |
| | phenethyl phenyl acetate | FL/FR |
| lactonic |
| gamma- | octalactone | FL/FR |
| medicinal |
| | dimethyl benzyl carbinol | FL/FR |
| oily |
| 2- | methyl naphthalene | FL/FR |
| powdery |
| beta- | naphthyl ethyl ether | FL/FR |
| rummy |
| iso | butyl formate | FL/FR |
| soapy |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| 1- | dodecanol | FL/FR |
| spicy |
| | allspice oil | FL/FR |
| | benzyl cinnamate | FL/FR |
| | benzyl isoeugenol | FL/FR |
| | cassia bark oil china | FL/FR |
| | clove bud oil | FL/FR |
| black | currant bud absolute | FL/FR |
| iso | eugenyl acetate | FL/FR |
| | ginger root absolute | FL/FR |
| | methyl isoeugenol | FL/FR |
| | nutmeg oil | FL/FR |
| black | pepper oil | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| | pimenta acris leaf oil | FL/FR |
| tea |
| | tea leaf absolute | FL/FR |
| tropical |
| alpha- | amyl cinnamaldehyde | FL/FR |
| vanilla |
| | ethyl vanillin | FL/FR |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| | vanilla oleoresin bourbon | FL/FR |
| | vanillyl acetate | FL/FR |
| waxy |
| iso | amyl decanoate | FL/FR |
| | decanal (aldehyde C-10) | FL/FR |
| | ethyl laurate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | hydroxycitronellal | FL/FR |
| 2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
| | mimosa absolute france | FL/FR |
| | nonanol | FL/FR |
| woody |
| | ambrette seed absolute | FL/FR |
| | ambroxan | FL/FR |
| | amyris wood oil | FL/FR |
| iso | bornyl acetate | FL/FR |
| | cistus twig/leaf oil | FL/FR |
| | frankincense oil | FL/FR |
| | guaiacwood oil | FL/FR |
| beta- | ionone | FL/FR |
| | methyl cedryl ketone | FL/FR |
| | patchouli oil | FL/FR |
| iso | pulegyl acetate | FL/FR |
| | sandalwood oil | FL/FR |
| | sandalwood oil CO2 extract | FL/FR |
| | spruce needle oil canada | FL/FR |
| | vetiver oil haiti | FL/FR |
| |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cervolide (Givaudan) | | 2,7- | dioxacycloheptadecan-1-one | | 1,6- | dioxacycloheptadecan-17-one | | 1,6- | dioxacycloheptadecan-7-one | | 12-oxa | hexadecan-16-olide | | 12-oxa | hexadecanolide | | 12-oxa-1,16- | hexadecanolide | | | hibiscolide | | 16- | hydroxy-12-oxahexadecanoic acid omega-lactone | | 11-(4- | hydroxybutoxy) undecanoic acid omicron-lactone | | | musk 174 | | | musk 781 (IFF) | | | musk decanolide | | | undecanoic acid, 11-(4-hydroxybutoxy)-, .omicron.-lactone | | | undecanoic acid, 11-(4-hydroxybutoxy)-, omicron-lactone |
Articles:
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