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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 80.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 286.10 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.003000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 261.00 °F. TCC ( 127.22 °C. )
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| logP (o/w): | 4.050 (est) |
| Soluble in: |
| | alcohol | | | water, 261 mg/L @ 20 °C (exp) |
| Stability: |
| | alcoholic - good | | | antiperspirant spray - poor | | | APC (pH = 10) - moderate | | | candles - good | | | damp fabric - moderate | | | dry fabric - moderate | | | liquid bleach - poor | | | pH = 2 - moderate | | | powder detergent - moderate | | | powder detergent + activator - moderate | | | soap - good | | | toiletries - good |
Organoleptic Properties:
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| Odor Type: woody |
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| Odor Strength: | medium |
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| Substantivity: | 96 hour(s) at 100.00 % |
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| | woody woody old wood amber tobacco herbal |
Odor Description: at 100.00 %. | woody old wood amber tobacco hot herbal Luebke, William tgsc, (1987) |
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| Odor and/or flavor descriptions from others (if found). |
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| Givaudan |
| Kephalis |
| Odor Description: | Rich, Warm, Woody, Ambery, Tobacco Kephalis is a very versatile and rich product, used as a long lasting heart/basic note. It blends well with floral notes (jasmine, rose, violet, lavender, etc.) as well as sophisticated amber, woody-aldehydic, tobacco and masculine creations. |
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| PerfumersWorld |
| Kephalis |
| Odor Description: | woody herbal character somewhat reminiscent of honey Blends-well-with - +iso-E-Super |
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| Pell Wall Perfumes |
| Kephalis |
| Odor Description: | Rich, Warm, Woody, Ambery, Tobacco The Scent and Chemistry authors point out that Kephalis, just like Cashmeran, is often a key component of synthetic reconstructions of agarwood. |
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Cosmetic Information:
Suppliers:
| ACS International |
| Tetrambrone
Odor: woody amber tobacco herbal |
| Operational Capabilities |
| Augustus Oils |
| Kephalis
|
| Services |
| BOC Sciences |
| For experimental / research use only. |
| Kephalis
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| Creatingperfume.com |
| Kephalis (Givaudan)
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| Ernesto Ventós |
| KEPHALIS
Odor: FLORAL, AMBER |
| Givaudan |
| Kephalis
Odor: Rich, Warm, Woody, Ambery, Tobacco Use: Kephalis is a very versatile and rich product, used as a long lasting heart/basic note. It blends well with floral notes (jasmine, rose, violet, lavender, etc.) as well as sophisticated amber, woody-aldehydic, tobacco and masculine creations. |
| Indukern F&F |
| KEPHALIS
Odor: AMBER, WOODY, WARM, TOBACCO |
| Lluch Essence |
| WOODAROM
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| M&U International |
| Kephalis
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| Moellhausen |
| KEPHALIS
Odor: honey, amberwoody note |
| OQEMA |
| Kephalan
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| Organica Aromatics |
| KEPHALOR
Min 80% |
| PCW France |
| Kephalis
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| Steps to a fragranced product |
| Pell Wall Perfumes |
| Kephalis
Odor: Rich, Warm, Woody, Ambery, Tobacco Use: The Scent and Chemistry authors point out that Kephalis, just like Cashmeran, is often a key component of synthetic reconstructions of agarwood. |
| Penta International |
| KEPHALIS
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| PerfumersWorld |
| Kephalis
Odor: woody herbal character somewhat reminiscent of honey Use: Blends-well-with - +iso-E-Super |
| Perfumery Laboratory |
| KEFALIS Givaudan (KEPHALIS Givaudan)
Odor: Rich, warm, woody, amber fragrance with a hint of tobacco |
| The Perfumers Apprentice |
| Kephalis
Odor: Rich, Warm, Woody-Ambery, Tobacco Use: blends well with floral notes (jasmine, rose, violet, lavender, etc.) as well as sophisticated amber, woody-aldehydic and tobacco |
| Vigon International |
| Kephalis
Odor: Rich, Warm, Woody, Ambery, Tobacco |
Safety Information:
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Human Experience: |
| 10 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 835, 1982.
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| Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Chemical Toxicology. Vol. 20, Pg. 835, 1982.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for woody cyclohexanone usage levels up to: | | | 8.0000 % in the fragrance concentrate.
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| Recommendation for woody cyclohexanone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
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| For Odor |
| aldehydic |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| 2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
| amber |
| (Z)- | abienol | FL/FR |
| | acetoxymethyl isolongifolene | FR |
| | amber acetate | FR |
| | amber butanol | FR |
| | amber carane | FR |
| | amber cyclohexanol | FR |
| | amber oxepin | FR |
| | amber specialty | FR |
| | ambermax 50 (Givaudan) | FR |
| | ambrette seed oil | FL/FR |
| | ambroxan | FL/FR |
| | angelica root oil | FL/FR |
| | cistus ladaniferus resin | FR |
| | cistus ladaniferus resinoid | FL/FR |
| | formoxymethyl isolongifolene | FR |
| | hydroxymethyl isolongifolene 50% in dpg | FR |
| | labdanum absolute | FL/FR |
| | labdanum oil | FL/FR |
| animal |
| | ambergris tincture replacer | FR |
| iso | butyl quinoline | FR |
| | costus valerolactone | FR |
| anisic |
| para- | anisaldehyde | FL/FR |
| balsamic |
| | amyris wood oil | FL/FR |
| siam | benzoin resinoid | FL/FR |
| | benzophenone | FR |
| | benzyl benzoate | FL/FR |
| | benzyl salicylate | FL/FR |
| iso | bornyl acetate | FL/FR |
| laevo- | bornyl acetate | FL/FR |
| iso | butyl benzoate | FL/FR |
| iso | butyl cinnamate | FL/FR |
| | cinnamyl alcohol | FL/FR |
| | ethyl cinnamate | FL/FR |
| | fir balsam absolute | FR |
| | fir carboxylate | FR |
| | mastic gum resin | FR |
| | methyl (E)-cinnamate | FL/FR |
| | methyl hydrogenated rosinate | FR |
| | myrrh oil | FL/FR |
| | opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR |
| | opoponax resin (commiphora erythraea var. glabrescens engler) | FL/FR |
| | opoponax resinoid (commiphora erythraea var. glabrescens engle) | FR |
| | opoponax resinoid replacer | FR |
| | oriental specialty | FR |
| 3- | phenyl propyl alcohol | FL/FR |
| | sclareol | FL/FR |
| | styrax resin (liquidambar styraciflua) | FL/FR |
| | styrax resinoid (liquidambar styraciflua) | FL/FR |
| berry |
| | raspberry ketone | FL/FR |
| chocolate |
| iso | butyl phenyl acetate | FL/FR |
| citrus |
| | bergamot oil bergaptene reduced italy | FL/FR |
| coconut |
| gamma- | heptalactone | FL/FR |
| gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| dusty |
| | woody furan | FR |
| earthy |
| | methyl undecylenate | FL/FR |
| fatty |
| | coconut absolute | FL/FR |
| | decanol | FL/FR |
| floral |
| | acetophenone | FL/FR |
| alpha- | amyl cinnamaldehyde | FL/FR |
| iso | amyl salicylate | FL/FR |
| | bois de rose oil brazil | FL/FR |
| iso | butyl salicylate | FL/FR |
| | citronellol | FL/FR |
| | coriander seed oil | FL/FR |
| | cyclamen aldehyde | FL/FR |
| | dimethyl benzyl carbinol | FL/FR |
| | dimethyl benzyl carbinyl acetate | FL/FR |
| | dimethyl benzyl carbinyl butyrate | FL/FR |
| | ethyl phenyl acetate | FL/FR |
| | floral pyranol | FR |
| | gardenia decalone | FR |
| | heliotropin | FL/FR |
| | heliotropyl acetone | FL/FR |
| | heliotropyl diethyl acetal | FR |
| (Z)-3- | hexen-1-yl salicylate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | ho leaf oil | FR |
| | hyacinth ether | FR |
| | hydroxycitronellal | FL/FR |
| | ilex paraguariensis oleoresin | FL/FR |
| | leerall | FR |
| laevo- | linalool | FL/FR |
| | linalool | FL/FR |
| | linalool oxide | FL/FR |
| para- | methyl acetophenone | FL/FR |
| | methyl dihydrojasmonate | FL/FR |
| | muguet carboxaldehyde | FR |
| | nerolidol | FL/FR |
| | ocean propanal | FL/FR |
| | orris pyridine 25% IPM | FR |
| | phenethyl alcohol | FL/FR |
| | phenethyl phenyl acetate | FL/FR |
| | phenethyl salicylate | FL/FR |
| | rhodinol | FL/FR |
| | rose butanoate | FL/FR |
| | tetrahydrolinalool | FL/FR |
| fruity |
| | balsam specialty | FR |
| | fruity cyclopentanone | FR |
| | tropical ionone | FL/FR |
| green |
| | diphenyl oxide | FL/FR |
| (Z)-3- | hexen-1-yl benzoate | FL/FR |
| | phenyl acetaldehyde dimethyl acetal | FL/FR |
| 3- | phenyl propionaldehyde | FL/FR |
| hay |
| | hay absolute | FR |
| | woodruff absolute | FR |
| herbal |
| (+)-alpha- | campholenic aldehyde | FL/FR |
| | carum carvi fruit oil | FL/FR |
| | clary sage oil france | FL/FR |
| | daucus carota fruit oil | FL/FR |
| | linalyl acetate | FL/FR |
| | nopyl acetate | FR |
| | romanal | FR |
| gamma- | valerolactone | FL/FR |
| mossy |
| | moss specialty | FR |
| | veramoss (IFF) | FR |
| naphthyl |
| beta- | naphthyl ethyl ether | FL/FR |
| oily |
| | mcp acetate | FR |
| powdery |
| para- | anisyl alcohol | FL/FR |
| | midnight passion fragrance | FR |
| spicy |
| | angelica seed absolute | FL/FR |
| | benzyl isoeugenol | FL/FR |
| | cassia bark oil china | FL/FR |
| | clove bud oil | FL/FR |
| 4- | ethyl guaiacol | FL/FR |
| | eugenol | FL/FR |
| iso | eugenyl acetate | FL/FR |
| alpha- | methyl cinnamaldehyde | FL/FR |
| | methyl isoeugenol | FL/FR |
| | pimenta acris leaf oil | FL/FR |
| terpenic |
| | angelica seed oil | FL/FR |
| | cypress leaf oil | FR |
| alpha- | terpineol | FL/FR |
| thujonic |
| | armoise oil | FR |
| | sage oil dalmatian | FL/FR |
| tobacco |
| 2,6,6- | trimethyl-2-hydroxycyclohexanone | FL/FR |
| tonka |
| | coumarin | FR |
| | deertongue absolute | FR |
| gamma- | hexalactone | FL/FR |
| | tonka bean absolute | FR |
| tropical |
| cis- | galbanum oxathiane | FL/FR |
| vanilla |
| | ethyl vanillin | FL/FR |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| | vanillyl acetate | FL/FR |
| waxy |
| 1- | dodecanol | FL/FR |
| | ethyl laurate | FL/FR |
| woody |
| | acetyl cedrene | FR |
| | amber carbinol | FR |
| | amber dioxane | FR |
| | amber formate | FR |
| | amber pentadecane | FR |
| atlas | cedarwood oil | FR |
| | cedarwood oil texas fractions | FR |
| alpha- | cedrene epoxide | FR |
| | cedryl formate | FR |
| | cedryl methyl ether | FR |
| | cistus ladaniferus gum | FR |
| | cistus twig/leaf oil | FL/FR |
| | dragons blood fragrance | FR |
| | frankincense resinoid | FL/FR |
| | frankincense resinoid replacer | FR |
| | georgywood | FR |
| | guaiacwood oil | FL/FR |
| | gurjun balsam oil | FR |
| | hydroxyambran | FR |
| | incense specialty | FR |
| | labdanum concrete | FR |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| (4aR,5R,7aS,9R)- | octahydro-2,2,5,8,8,9a-hexamethyl-4h-4a,9-methanoazuleno(5,6-d)-1,3-dioxole | FR |
| | patchouli ethanone | FR |
| | patchouli oil | FL/FR |
| | patchouli woody amber fragrance | FR |
| | santall | FR |
| | spruce needle oil canada | FL/FR |
| | tetramethyl-4-methylene-2-heptanol | FR |
| | thuja occidentalis leaf oil | FL/FR |
| | tobacarol (IFF) | FR |
| | vetiver oil haiti | FL/FR |
| | vetiver specialty | FR |
| | woody acetate | FR |
| (Z)- | woody amylene | FR |
| | woody dioxolane | FR |
| | woody nonane (ethoxy) | FR |
| | woody propanol | FR |
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| For Flavor |
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| No flavor group found for these |
| | cistus ladaniferus resinoid | FL/FR |
| | ilex paraguariensis oleoresin | FL/FR |
| | methyl (E)-cinnamate | FL/FR |
| 2,6,6- | trimethyl-2-hydroxycyclohexanone | FL/FR |
| amber |
| | ambrette seed oil | FL/FR |
| | angelica seed oil | FL/FR |
| | labdanum absolute | FL/FR |
| | labdanum oil | FL/FR |
| balsamic |
| siam | benzoin resinoid | FL/FR |
| | benzyl benzoate | FL/FR |
| | benzyl salicylate | FL/FR |
| laevo- | bornyl acetate | FL/FR |
| iso | butyl cinnamate | FL/FR |
| | ethyl cinnamate | FL/FR |
| | myrrh oil | FL/FR |
| | opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR |
| | opoponax resin (commiphora erythraea var. glabrescens engler) | FL/FR |
| | styrax resin (liquidambar styraciflua) | FL/FR |
| | styrax resinoid (liquidambar styraciflua) | FL/FR |
| berry |
| | heliotropyl acetone | FL/FR |
| | raspberry ketone | FL/FR |
| cherry |
| | heliotropin | FL/FR |
| citrus |
| | bergamot oil bergaptene reduced italy | FL/FR |
| laevo- | linalool | FL/FR |
| | linalool | FL/FR |
| alpha- | terpineol | FL/FR |
| cocoa |
| iso | butyl phenyl acetate | FL/FR |
| coconut |
| gamma- | nonalactone (aldehyde C-18 (so-called)) | FL/FR |
| cooling |
| iso | butyl salicylate | FL/FR |
| creamy |
| para- | anisaldehyde | FL/FR |
| gamma- | hexalactone | FL/FR |
| para- | methyl acetophenone | FL/FR |
| fatty |
| | coconut absolute | FL/FR |
| (Z)-3- | hexen-1-yl benzoate | FL/FR |
| floral |
| | bois de rose oil brazil | FL/FR |
| | citronellol | FL/FR |
| | dimethyl benzyl carbinyl acetate | FL/FR |
| | dimethyl benzyl carbinyl butyrate | FL/FR |
| | linalyl acetate | FL/FR |
| | methyl dihydrojasmonate | FL/FR |
| | ocean propanal | FL/FR |
| | phenethyl alcohol | FL/FR |
| | rhodinol | FL/FR |
| | tetrahydrolinalool | FL/FR |
| | tropical ionone | FL/FR |
| fruity |
| para- | anisyl alcohol | FL/FR |
| iso | butyl benzoate | FL/FR |
| | rose butanoate | FL/FR |
| green |
| iso | amyl salicylate | FL/FR |
| | angelica root oil | FL/FR |
| (+)-alpha- | campholenic aldehyde | FL/FR |
| | cinnamyl alcohol | FL/FR |
| | cyclamen aldehyde | FL/FR |
| | diphenyl oxide | FL/FR |
| cis- | galbanum oxathiane | FL/FR |
| (Z)-3- | hexen-1-yl salicylate | FL/FR |
| | linalool oxide | FL/FR |
| | nerolidol | FL/FR |
| | phenyl acetaldehyde dimethyl acetal | FL/FR |
| 3- | phenyl propionaldehyde | FL/FR |
| herbal |
| | carum carvi fruit oil | FL/FR |
| | clary sage oil france | FL/FR |
| | coriander seed oil | FL/FR |
| | daucus carota fruit oil | FL/FR |
| honey |
| | ethyl phenyl acetate | FL/FR |
| | phenethyl phenyl acetate | FL/FR |
| lactonic |
| gamma- | heptalactone | FL/FR |
| medicinal |
| | dimethyl benzyl carbinol | FL/FR |
| | phenethyl salicylate | FL/FR |
| powdery |
| | acetophenone | FL/FR |
| beta- | naphthyl ethyl ether | FL/FR |
| smoky |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| soapy |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| 1- | dodecanol | FL/FR |
| spicy |
| | angelica seed absolute | FL/FR |
| | benzyl isoeugenol | FL/FR |
| | cassia bark oil china | FL/FR |
| | clove bud oil | FL/FR |
| | eugenol | FL/FR |
| iso | eugenyl acetate | FL/FR |
| alpha- | methyl cinnamaldehyde | FL/FR |
| | methyl isoeugenol | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| | pimenta acris leaf oil | FL/FR |
| thujonic |
| | sage oil dalmatian | FL/FR |
| tonka |
| gamma- | valerolactone | FL/FR |
| tropical |
| alpha- | amyl cinnamaldehyde | FL/FR |
| vanilla |
| | ethyl vanillin | FL/FR |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| | vanillyl acetate | FL/FR |
| waxy |
| | decanol | FL/FR |
| | ethyl laurate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | hydroxycitronellal | FL/FR |
| 2- | methyl undecanal (aldehyde C-12 mna) | FL/FR |
| | methyl undecylenate | FL/FR |
| woody |
| (Z)- | abienol | FL/FR |
| | ambroxan | FL/FR |
| | amyris wood oil | FL/FR |
| iso | bornyl acetate | FL/FR |
| | cistus twig/leaf oil | FL/FR |
| 4- | ethyl guaiacol | FL/FR |
| | frankincense resinoid | FL/FR |
| | guaiacwood oil | FL/FR |
| | patchouli oil | FL/FR |
| | sclareol | FL/FR |
| | spruce needle oil canada | FL/FR |
| | thuja occidentalis leaf oil | FL/FR |
| | vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cyclohexanone, 4-(1-ethoxyethenyl)-3,3,5,5-tetramethyl- | | 4-(1- | ethoxyethenyl)-3,3,5,5-tetramethylcyclohexan-1-one | | 4-(1- | ethoxyethenyl)-3,3,5,5-tetramethylcyclohexanone | | 4-(1- | ethoxyvinyl)-3,3,5,5-tetramethyl cyclohexanone | | 4-(1- | ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone | | 3,3,5,5- | etramethyl-4-ethoxyvinylcyclohexanone | | | kephalan | | | kephalis (Givaudan) | | | kephalor | | | tetrambrone (A.C.S. International) | | 3,3,5,5- | tetramethyl-4-(1-ethoxyvinyl) cyclohexanone | | 3,3,5,5- | tetramethyl-4-(1-ethoxyvinyl)-1-cyclohexanone | | 3,3,5,5- | tetramethyl-4-(1-ethoxyvinyl)cyclohexanone | | 3,3,5,5- | tetramethyl-4-ethoxyvinyl cyclohexanone | | 3,3,5,5- | tetramethyl-4-ethoxyvinylcyclohexanone | | | woody cyclohexanone |
Articles:
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