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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | off-white crystals or solid (est) |
| Assay: | 97.00 to 100.00 % sum of isomers
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 37.00 to 58.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 393.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.000111 mmHg @ 25.00 °C. (est) |
| Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. )
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| logP (o/w): | 4.536 (est) |
| Soluble in: |
| | alcohol | | | diethyl phthalate | | | most solvents | | | paraffin oil | | | water, 0.2545 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
| Stability: |
| | acids | | | alcohol, good | | | alkalis | | | bar soap, good | | | cream rinse, excellent | | | deo pump spray, good | | | fabric softener, good | | | hand cream, good | | | liquid detergent, good | | | non-discoloring in most media | | | oxidizing agents | | | reducing agents |
Organoleptic Properties:
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| Odor Type: musk |
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| Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
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| Substantivity: | 384 hour(s) at 10.00 % in dipropylene glycol |
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| | sweet musk amber powdery dry fruity |
Odor Description: at 10.00 % in dipropylene glycol. | strong sweet musk amber powdery dry fruity Luebke, William tgsc, (1985) |
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| Odor and/or flavor descriptions from others (if found). |
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| PerfumersWorld |
| Fixolide |
| Odor Description: | strong sweet fruity musk powdery |
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| Indukern F&F |
| PHANTOLID |
| Odor Description: | MUSK, SWEET, CLEAN |
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| Pell Wall Perfumes |
| Tonalid |
| Odor Description: | Musk, sweet, amber, clean, powdery, dry, fruit. Strong Crystals of this widely used, clean, diffusive musk: one of the few early non-Nitro-musks that has stood the test of time and continues to be used extensively in modern perfumery. According to Scent and Chemistry, “Tonalide/Fixolide gives a very special accord with coumarin that is much desirable in constructing male fougere perfumes.” |
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Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| 5-Acetyl-1,1,2,3,3,6-hexamethylindane
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| Ernesto Ventós |
| PHANTOLID CRYSTALS PFW
Odor: CLEAN AND SWEET MUSK |
| Indukern F&F |
| PHANTOLID
Odor: MUSK, SWEET, CLEAN |
| Keva |
| PHANTOLID CRYSTALS
Odor: has a clean sweet musk odour |
| Lluch Essence |
| PHANTOLID CRYSTALS ® PFW
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| Moellhausen |
| PHANTOLID
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| PCW France |
| Phantolid® crystals
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| Steps to a fragranced product |
| Pell Wall Perfumes |
| Tonalid
Odor: Musk, sweet, amber, clean, powdery, dry, fruit. Strong Use: Crystals of this widely used, clean, diffusive musk: one of the few early non-Nitro-musks that has stood the test of time and continues to be used extensively in modern perfumery. According to Scent and Chemistry, “Tonalide/Fixolide gives a very special accord with coumarin that is much desirable in constructing male fougere perfumes.” |
| Penta International |
| FIXOLIDE
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| Penta International |
| PHANTOLIDE
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| PerfumersWorld |
| Fixolide 10% in DPG
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| PerfumersWorld |
| Fixolide
Odor: strong sweet fruity musk powdery |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Phantolide
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| SRS Aromatics |
| PHANTOLID
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| The John D. Walsh Company |
| Phantolid Crystals
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| Zanos |
| Ganolid
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Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| IFRA Critical Effect: | Phototoxicity |
| IFRA fragrance material specification: | | | The Standard is set due to the phototoxic effects of the material. The limit only applies to applications on skin, excluding rinse-off products.
If combinations of phototoxic fragrance ingredients are used, the use levels have to be reduced accordingly. The sum of the concentrations of all phototoxic ingredients, expressed in % of their recommended maximum level in the consumer product shall not exceed 100. |
| IFRA: | View Standard |
| View IFRA Standards Library for complete information. |
| Please review Amendment 49 IFRA documentation for complete information. |
| IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): |
| Category 1: Products applied to the lips |
| 2.00 % |
| Category 2: Products applied to the axillae |
| 2.00 % |
| Category 3: Products applied to the face/body using fingertips |
| 2.00 % |
| Category 4: Products related to fine fragrance |
| 2.00 % |
| | Category 5: Products applied to the face and body using the hands (palms), primarily leave-on |
| Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on |
| 2.00 % |
| Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on |
| 2.00 % |
| Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on |
| 2.00 % |
| Category 5D: Baby Creams, baby Oils and baby talc |
| 2.00 % |
| Category 6: Products with oral and lip exposure |
| 2.00 % |
| | Category 7: Products applied to the hair with some hand contact |
| Category 7A: Rinse-off products applied to the hair with some hand contact |
| No Restriction % |
| Category 7B: Leave-on products applied to the hair with some hand contact |
| 2.00 % |
| Category 8: Products with significant anogenital exposure |
| 2.00 % |
| Category 9: Products with body and hand exposure, primarily rinse off |
| No Restriction % |
| | Category 10: Household care products with mostly hand contact |
| Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) |
| No Restriction % |
| Category 10B: Household aerosol/spray products |
| 2.00 % |
| | Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate |
| Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure |
| No Restriction % |
| Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure |
| 2.00 % |
| Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin |
| No Restriction |
| | Notes: |
| IFRA FLAVOR REQUIREMENTS: |
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. |
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| Recommendation for musk indane flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
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| For Odor |
| No odor group found for these |
| | amber romance fragrance | FR |
| (Z)-iso | ambrettolide | FR |
| aldehydic |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| amber |
| | amber oxepin | FR |
| | amber powdery floral fragrance | FR |
| | amber spirolene | FR |
| | ambergris specialty | FR |
| | ambrette seed absolute | FL/FR |
| | ambrette seed oil | FL/FR |
| | ambrette seed oil CO2 extract | FL/FR |
| | ambrette seed oil replacer | FR |
| | ambroxan | FL/FR |
| | angelica root oil | FL/FR |
| | cistus ladaniferus resinoid | FL/FR |
| (cis+trans)-6,6a,7,8,9,9a- | hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| | muscomer | FR |
| animal |
| | animal carbolactone | FR |
| | costus valerolactone | FR |
| para- | cresyl phenyl acetate | FL/FR |
| | indole | FL/FR |
| 2- | methyl-4-(camphenyl-8) cyclohexanone | FR |
| balsamic |
| iso | amyl benzoate | FL/FR |
| | amyris wood oil | FL/FR |
| siam | benzoin resinoid | FL/FR |
| | benzyl salicylate | FL/FR |
| iso | butyl cinnamate | FL/FR |
| | cinnamyl alcohol | FL/FR |
| | clover nitrile | FR |
| | ethyl cinnamate | FL/FR |
| | fir balsam absolute | FR |
| | methyl (E)-cinnamate | FL/FR |
| | myrrh oil | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| berry |
| | raspberry ketone | FL/FR |
| | raspberry ketone acetate | FL/FR |
| | raspberry ketone methyl ether | FL/FR |
| caramellic |
| | ethyl maltol | FL/FR |
| coconut |
| gamma- | heptalactone | FL/FR |
| gamma- | octalactone | FL/FR |
| fatty |
| | decanol | FL/FR |
| floral |
| alpha- | amyl cinnamaldehyde | FL/FR |
| iso | amyl salicylate | FL/FR |
| | bois de rose oil brazil | FL/FR |
| | citronellol | FL/FR |
| | coriander seed oil | FL/FR |
| | cyclamen aldehyde | FL/FR |
| 9- | decen-1-ol | FL/FR |
| | dimethyl benzyl carbinol | FL/FR |
| | floral pyranol | FR |
| | heliotropin | FL/FR |
| | heliotropyl acetone | FL/FR |
| | heliotropyl diethyl acetal | FR |
| (Z)-3- | hexen-1-yl salicylate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | ho leaf oil | FR |
| | hyacinth ether | FR |
| | hydroxycitronellal | FL/FR |
| laevo- | linalool | FL/FR |
| | linalool oxide | FL/FR |
| para- | methyl acetophenone | FL/FR |
| | methyl dihydrojasmonate | FL/FR |
| alpha-iso | methyl ionone (50% min.) | FL/FR |
| alpha-iso | methyl ionone (90% min.) | FL/FR |
| | muguet carboxaldehyde | FR |
| | muguet octadienol | FR |
| | nerolidol | FL/FR |
| | ocean propanal | FL/FR |
| | orris pyridine 25% IPM | FR |
| | papaya isobutyrate | FL/FR |
| | phenethyl alcohol | FL/FR |
| | phenethyl phenyl acetate | FL/FR |
| | rhodinol | FL/FR |
| fruity |
| | acetyl methyl anthranilate | FL/FR |
| | allyl amyl glycolate | FR |
| gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| | valeriana officinalis root extract | FL/FR |
| hay |
| | hay absolute | FR |
| herbal |
| | clary sage oil france | FL/FR |
| | daucus carota fruit oil | FL/FR |
| marine |
| | marine pyridine | FR |
| melon |
| | watermelon ketone | FR |
| mossy |
| | oakmoss absolute | FL/FR |
| | veramoss (IFF) | FR |
| musk |
| | musk lactone | FR |
| | musk methyl ketone | FR |
| | musk tetralin | FL/FR |
| 6,7,8,9- | tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| naphthyl |
| beta- | naphthyl ethyl ether | FL/FR |
| powdery |
| para- | anisyl alcohol | FL/FR |
| alpha- | methyl ionone | FL/FR |
| (E)-alpha- | methyl ionone (74-80%) | FL/FR |
| | midnight passion fragrance | FR |
| spicy |
| para- | anisyl formate | FL/FR |
| | cassia bark oil china | FL/FR |
| iso | eugenyl acetate | FL/FR |
| alpha- | methyl cinnamaldehyde | FL/FR |
| | methyl isoeugenol | FL/FR |
| black | pepper oil | FL/FR |
| terpenic |
| | frankincense oil | FL/FR |
| tonka |
| | coumarin | FR |
| gamma- | hexalactone | FL/FR |
| | tonka bean absolute | FR |
| vanilla |
| | ethyl vanillin | FL/FR |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| | vanillyl acetate | FL/FR |
| waxy |
| | decyl acetate | FL/FR |
| 1- | dodecanol | FL/FR |
| | ethyl laurate | FL/FR |
| 1- | undecanol | FL/FR |
| woody |
| | acetyl cedrene | FR |
| | amber carbinol | FR |
| | cistus twig/leaf oil | FL/FR |
| | guaiacwood oil | FL/FR |
| | gurjun balsam oil | FR |
| | hydroxyambran | FR |
| | methyl cedryl ketone | FL/FR |
| | patchouli ethanone | FR |
| | patchouli oil | FL/FR |
| | santall | FR |
| | timber propanol | FR |
| | tobacarol (IFF) | FR |
| | vetiver oil haiti | FL/FR |
| | vetiver specialty | FR |
| | woody acetate | FR |
| (Z)- | woody amylene | FR |
| | woody epoxide | FR |
| | woody ether | FR |
| | woody propanol | FR |
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| For Flavor |
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| No flavor group found for these |
| | cistus ladaniferus resinoid | FL/FR |
| | methyl (E)-cinnamate | FL/FR |
| aldehydic |
| 1- | undecanol | FL/FR |
| amber |
| | ambrette seed oil | FL/FR |
| | ambrette seed oil CO2 extract | FL/FR |
| | musk tetralin | FL/FR |
| animal |
| | indole | FL/FR |
| balsamic |
| siam | benzoin resinoid | FL/FR |
| | benzyl salicylate | FL/FR |
| iso | butyl cinnamate | FL/FR |
| | ethyl cinnamate | FL/FR |
| | myrrh oil | FL/FR |
| berry |
| | heliotropyl acetone | FL/FR |
| | raspberry ketone | FL/FR |
| | raspberry ketone acetate | FL/FR |
| | raspberry ketone methyl ether | FL/FR |
| caramellic |
| | ethyl maltol | FL/FR |
| cherry |
| | heliotropin | FL/FR |
| citrus |
| laevo- | linalool | FL/FR |
| creamy |
| gamma- | hexalactone | FL/FR |
| para- | methyl acetophenone | FL/FR |
| gamma- | undecalactone (aldehyde C-14 (so-called)) | FL/FR |
| floral |
| | bois de rose oil brazil | FL/FR |
| | citronellol | FL/FR |
| | methyl dihydrojasmonate | FL/FR |
| alpha-iso | methyl ionone (50% min.) | FL/FR |
| (E)-alpha- | methyl ionone (74-80%) | FL/FR |
| alpha-iso | methyl ionone (90% min.) | FL/FR |
| | ocean propanal | FL/FR |
| | phenethyl alcohol | FL/FR |
| | rhodinol | FL/FR |
| fruity |
| | acetyl methyl anthranilate | FL/FR |
| iso | amyl benzoate | FL/FR |
| para- | anisyl alcohol | FL/FR |
| alpha- | methyl ionone | FL/FR |
| | valeriana officinalis root extract | FL/FR |
| green |
| iso | amyl salicylate | FL/FR |
| | angelica root oil | FL/FR |
| | cinnamyl alcohol | FL/FR |
| | cyclamen aldehyde | FL/FR |
| (Z)-3- | hexen-1-yl salicylate | FL/FR |
| | linalool oxide | FL/FR |
| | nerolidol | FL/FR |
| | oakmoss absolute | FL/FR |
| | papaya isobutyrate | FL/FR |
| herbal |
| | clary sage oil france | FL/FR |
| | coriander seed oil | FL/FR |
| | daucus carota fruit oil | FL/FR |
| honey |
| | phenethyl phenyl acetate | FL/FR |
| lactonic |
| gamma- | heptalactone | FL/FR |
| gamma- | octalactone | FL/FR |
| medicinal |
| | dimethyl benzyl carbinol | FL/FR |
| phenolic |
| para- | cresyl phenyl acetate | FL/FR |
| powdery |
| beta- | naphthyl ethyl ether | FL/FR |
| soapy |
| | dodecanal (aldehyde C-12 lauric) | FL/FR |
| 1- | dodecanol | FL/FR |
| spicy |
| para- | anisyl formate | FL/FR |
| | cassia bark oil china | FL/FR |
| iso | eugenyl acetate | FL/FR |
| alpha- | methyl cinnamaldehyde | FL/FR |
| | methyl isoeugenol | FL/FR |
| black | pepper oil | FL/FR |
| 3- | phenyl propyl alcohol | FL/FR |
| tropical |
| alpha- | amyl cinnamaldehyde | FL/FR |
| vanilla |
| | ethyl vanillin | FL/FR |
| | vanilla bean absolute (vanilla planifolia) | FL/FR |
| | vanillyl acetate | FL/FR |
| waxy |
| | decanol | FL/FR |
| 9- | decen-1-ol | FL/FR |
| | decyl acetate | FL/FR |
| | ethyl laurate | FL/FR |
| alpha- | hexyl cinnamaldehyde | FL/FR |
| | hydroxycitronellal | FL/FR |
| woody |
| | ambrette seed absolute | FL/FR |
| | ambroxan | FL/FR |
| | amyris wood oil | FL/FR |
| | cistus twig/leaf oil | FL/FR |
| | frankincense oil | FL/FR |
| | guaiacwood oil | FL/FR |
| | methyl cedryl ketone | FL/FR |
| | patchouli oil | FL/FR |
| | vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetyl hexamethyl indan | | 6- | acetyl-1,1,2,3,3,5-hexamethyl indan | | 5- | acetyl-1,1,2,3,3,6-hexamethyl indan | | 5- | acetyl-1,1,2,3,3,6-hexamethyl-1H-indane | | 1-(2,3- | dihydro-1,1,2,3,3,6-hexamethyl-1H-inden-5-yl) ethanone | | | fixolide (Givaudan) | | | fixolide, kosher | | | ganolid (tonalid) | | | ganolide | | 1-(1,1,2,3,3,6- | hexamethyl-2H-inden-5-yl)ethanone | | | INCI acetyl hexamethyl indan | | | musk indane | | | phantolid (PFW) | | | phantolid crystals (PFW) | | | tonalid (PFW) |
Articles:
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