costus root oil
saussurea lappa root oil
 
Notes:
Do not use on any part of the body because of potential sensitizing. Steam distilled from the roots of Saussurea Lappa. extract from roots of saussurea lappa used in perfumery & cosmetics; contains sesquiterpene lactones reported to cause contact hypersensitivity; structures of components. tsca definition 2008: extractives and their physically modified derivatives. saussurea lappa, compositae.
  • CJ Latta & Associates
    • CJ Latta & Associates, LLC
      Extensive Line
      Aromatic Chemicals and Organic Acids.
      CJ Latta & Associates is a distributor of specialty aromatics and organic acids used in the formulation of flavors and fragrance manufactured worldwide. We pride ourselves on our reputation for, fair pricing, quality and reliability. We’ve built our business on successfully sourcing and developing many challenging specialty chemicals and fine ingredients for our clients.
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      US Email: Chip Latta
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      Product(s):
      COSTUS OIL
       
  • Excellentia International
    • Excellentia International
      Ingredients by Nature
      Exceptional quality and excellence in meeting our customers requirements.
      Excellentia International was founded in 2010 through the merger of Excellentia Flavors LLC and Polarome International. Collectively, these companies account for more than one hundred years of industry experience, and are recognized for exceptional quality and excellence in meeting our customers’ requirements.
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      Costus Oil
       
  • Firmenich
    • Firmenich Inc.
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      Product(s):
      935880 COSTUS EO Kosher for flavor

      For creation in spirits tonalities and brown notes
       
       
  • Fleurchem
    • Fleurchem, Inc.
      Have A Flavorful Day
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      Product(s):
      costus root oil
       
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    • Lluch Essence S.L.
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      Product(s):
      COSTUS ROOTS OIL
       
  • Ultra International
    • Ultra International Limited
      Driven by a mutual passion for excellence.
      Ultra International is one of the leading company in the Flavors and Fragrance industry.
      Ultra International is one of the leading company in the Flavors and Fragrance industry with a vision to be the Essential Source of Sensory Innovation for customers, driven by a mutual passion for excellence. Through unique sensory expertise and consumer insight, Ultra provides customers with the taste and smell profiles that are key to their products' success. Our passion for Perfumes and Flavors, our Creativity and Innovation, together with our exceptional understanding of sensory perceptions and trends, have forged our world-class reputation.
      Email: Bhuvana Nageshwaran
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      Product(s):
      Costus Root Oil
       
  • Vigon International
    • Vigon International
      Passion for Simplicity
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      Product(s):
      503449 Costus Oil
       
Synonyms   Articles   Notes   Search
Name: saussurea lappa root oil
CAS Number: 8023-88-9 
FDA UNII: 2WF6750061
MDL: MFCD01771687
Category: flavoring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
FEMA Number: 2336 costus root oil
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):8023-88-9 ; COSTUS ROOT, OIL (SAUSSUREA LAPPA CLARKE)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.510 Natural flavoring substances and natural substances used in conjunction with flavors.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: pale yellow solid (est)
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
 water, 9.376 mg/L @ 25 °C (est)
Insoluble in:
 water
Stability:
 non-discoloring in most media
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: animal
 
Odor Strength: medium
 
Substantivity: 316 hour(s) at 100.00 %
 
 orris  green  hairy  woody  melon unripe melon  
Odor Description:
at 100.00 %. 
orris green hairy woody unripe melons
Luebke, William tgsc, (1983)
 
 
Flavor Type: orris
 
 costus  
Taste Description:
costus
 
Odor and/or flavor descriptions from others (if found).
 
Firmenich
COSTUS EO Kosher for flavor
Odor Description: orris green hairy woody unripe melons
Taste Description: Fatty metallic like herbal
For creation in spirits tonalities and brown notes
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: not used anymore
Synonyms   Articles   Notes   Search   Top
Suppliers:
CJ Latta & Associates
COSTUS OIL
Diffusions Aromatiques
COSTUS HUILE ESSENTIELLE (k) uniquement alim.
Diffusions Aromatiques
COSTUS HUILE ESSENTIELLE
Excellentia International
Costus Oil
Firmenich
COSTUS EO Kosher
for flavor
Flavor: Fatty metallic like herbal
For creation in spirits tonalities and brown notes
Fleurchem
costus root oil
India Essential Oils
Costus Root Oil
Indo World Trading
Costus Root Oil
Kanta Enterprises
Costus Roots Oil
Lluch Essence
COSTUS ROOTS OIL
Moellhausen
COSTUS 10% DPG
Nanda Medicinal Plants
Costus Root Oil
Odor: Extremely tenacious odor reminiscent of old precious wood. The odor has been compared to that of wet dog, human hair, or animal fur.
Noble Molecular Research
For experimental / research use only.
Costus Root Oil (cultivated)
Parchem
Costus Root Oil
Penta International
COSTUS ROOT OIL
Phoenix Aromas & Essential Oils
Costus Root Oil
Robertet
Costus Root Oil
Seasons and Harvest / Crop calendar
Sigma-Aldrich
Costus oil, natural, FG
Certified Food Grade Products
Silverline Chemicals
Costus Root Oil
Ultra International
Costus Root Oil
Crop Calendar
Vigon International
Costus Oil
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  3400 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 867, 1974.

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 12, Pg. 867, 1974.

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavoring agents
IFRA Critical Effect: Dermal sensitization
IFRA: View Standard
Recommendation for costus root oil usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -1.20000
beverages(nonalcoholic): -0.08000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -0.90000
fruit ices: -0.90000
gelatins / puddings: -0.10000
granulated sugar: --
gravies: --
hard candy: -1.90000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 8023-88-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
WGK Germany: 2
 saussurea lappa root oil
Chemidplus: 0008023889
RTECS: GN1775000 for cas# 8023-88-9
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References:
 saussurea lappa root oil
Canada Domestic Sub. List: 8023-88-9
Pubchem (sid): 135352797
Synonyms   Articles   Notes   Search   Top
Other Information:
FDA Substances Added to Food (formerly EAFUS): View
Export Tariff Code: 3301.29.6000
Wikipedia: View
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
 amyl undecylenateFL/FR
 satinaldehydeFL/FR
aldehydic
 nonanal (aldehyde C-9)FL/FR
10-undecenal (aldehyde C-11 undecylenic)FL/FR
amber
 angelica root oilFL/FR
 cistus ladaniferus resinoidFL/FR
animal
 animal carbolactoneFR
isobutyl quinolineFR
 costus valerolactoneFR
para-cresyl caprylateFL/FR
 methyl (E)-2-octenoateFL/FR
balsamic
isoamyl benzoateFL/FR
 amyris wood oilFL/FR
siam benzoin resinoidFL/FR
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
 betula pubescens bud oilFL/FR
laevo-bornyl acetateFL/FR
isobornyl acetateFL/FR
isobutyl cinnamateFL/FR
 cinnamyl alcoholFL/FR
 clover nitrileFR
 ethyl cinnamateFL/FR
 fir balsam absoluteFR
 mastic gum resinFR
 methyl (E)-cinnamateFL/FR
3-phenyl propyl alcoholFL/FR
berry
 raspberry ketoneFL/FR
citrus
 bergamot oil bergaptene reduced italyFL/FR
coconut
gamma-heptalactoneFL/FR
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
gamma-octalactoneFL/FR
fatty
 butyl undecylenateFL/FR
 decanolFL/FR
floral
alpha-amyl cinnamaldehydeFL/FR
isoamyl salicylateFL/FR
 benzyl acetateFL/FR
 benzyl alcoholFL/FR
 bois de rose oil brazilFL/FR
 boronia absoluteFL/FR
isobutyl salicylateFL/FR
 cassie absoluteFL/FR
 citronellolFL/FR
 coriander seed oilFL/FR
 cyclamen aldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
 dimethyl benzyl carbinolFL/FR
 floral pyranolFR
 geranium oil bourbonFL/FR
 heliotropinFL/FR
 heliotropyl acetoneFL/FR
 heliotropyl diethyl acetalFR
(Z)-3-hexen-1-yl salicylateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 hyacinth etherFR
 linaloolFL/FR
laevo-linaloolFL/FR
 linalool oxideFL/FR
 methyl dihydrojasmonateFL/FR
 mimosa absolute franceFL/FR
 muguet carboxaldehydeFR
 nerolFL/FR
 nerolidolFL/FR
 nonanolFL/FR
 ocean propanalFL/FR
 orange leaf absoluteFL/FR
 orris pyridine 25% IPMFR
 phenethyl alcoholFL/FR
 phenethyl phenyl acetateFL/FR
 phenethyl salicylateFL/FR
 rhodinolFL/FR
 rose butanoateFL/FR
 tetrahydrolinaloolFL/FR
(E)-2,5,9-trimethyl-4,9-decadien-1-alFR
 ylang ylang flower oilFL/FR
fruity
 benzyl propionateFL/FR
gamma-decalactoneFL/FR
 green acetateFR
 methyl heptanoateFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
green
para-dimethyl hydroquinoneFL/FR
 galbanum oleoresinFL/FR
 galbanum resinoidFL/FR
 methyl heptine carbonateFL/FR
 methyl octine carbonateFL/FR
 phenyl acetaldehyde dimethyl acetalFL/FR
hay
 hay absoluteFR
herbal
 acorus calamus root oilFR
(+)-alpha-campholenic aldehydeFL/FR
 canarium luzonicum oilFL/FR
 clary sage oil franceFL/FR
 daucus carota fruit oilFL/FR
isodihydrolavandulalFL/FR
marine
green algae absoluteFL/FR
 marine pyridineFR
minty
isopulegolFL/FR
(-)-isopulegolFL/FR
mossy
 oakmoss absoluteFL/FR
 veramoss (IFF)FR
naphthyl
beta-naphthyl ethyl etherFL/FR
isoeugenyl formateFL/FR
powdery
para-anisyl alcoholFL/FR
spicy
 benzyl isoeugenolFL/FR
 cuminaldehydeFL/FR
isoeugenyl acetateFL/FR
 ginger root oil chinaFL/FR
 levisticum officinale root oilFL/FR
2-octanolFL/FR
black pepper oilFL/FR
black pepper oil CO2 extractFL/FR
terpenic
alpha-phellandreneFL/FR
alpha-terpineolFL/FR
tonka
 coumarinFR
 flouve absoluteFR
gamma-hexalactoneFL/FR
 tonka bean absoluteFR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
waxy
 decyl acetateFL/FR
woody
 amber carbinolFR
alpha-farneseneFL/FR
alpha-farnesene isomerFL/FR
 guaiacwood oilFL/FR
 humulus lupulus extractFL/FR
 methyl cedryl ketoneFL/FR
 patchouli ethanoneFR
 patchouli oilFL/FR
 sandalwood oilFL/FR
 santallFR
(±)-tetrahydronootkatoneFL/FR
 tobacarol (IFF)FR
 vetiver oil haitiFL/FR
 woody acetateFR
(Z)-woody amyleneFR
 
For Flavor
 
No flavor group found for these
green algae absoluteFL/FR
 amyl undecylenateFL/FR
 betula pubescens bud oilFL/FR
 cistus ladaniferus resinoidFL/FR
 costus root absoluteFL
 costus root resinoidFL
 elecampane root oilFL
isoeugenyl formateFL/FR
 methyl (E)-cinnamateFL/FR
(±)-tetrahydronootkatoneFL/FR
2,4,4-trimethyl-1,3-oxathianeFL
aldehydic
 nonanal (aldehyde C-9)FL/FR
animal
para-cresyl caprylateFL/FR
balsamic
siam benzoin resinoidFL/FR
 benzyl benzoateFL/FR
 benzyl salicylateFL/FR
laevo-bornyl acetateFL/FR
isobutyl cinnamateFL/FR
 ethyl cinnamateFL/FR
berry
 heliotropyl acetoneFL/FR
 raspberry ketoneFL/FR
cherry
 heliotropinFL/FR
citrus
 bergamot oil bergaptene reduced italyFL/FR
 linaloolFL/FR
laevo-linaloolFL/FR
 nerolFL/FR
alpha-terpineolFL/FR
coconut
gamma-nonalactone (aldehyde C-18 (so-called))FL/FR
cooling
isobutyl salicylateFL/FR
creamy
gamma-hexalactoneFL/FR
gamma-undecalactone (aldehyde C-14 (so-called))FL/FR
fatty
10-undecenal (aldehyde C-11 undecylenic)FL/FR
floral
 bois de rose oil brazilFL/FR
 citronellolFL/FR
 geranium oil bourbonFL/FR
 methyl dihydrojasmonateFL/FR
 ocean propanalFL/FR
 orange leaf absoluteFL/FR
 phenethyl alcoholFL/FR
 rhodinolFL/FR
 satinaldehydeFL/FR
 tetrahydrolinaloolFL/FR
 ylang ylang flower oilFL/FR
fruity
isoamyl benzoateFL/FR
para-anisyl alcoholFL/FR
 benzyl acetateFL/FR
 benzyl alcoholFL/FR
 benzyl propionateFL/FR
 boronia absoluteFL/FR
gamma-decalactoneFL/FR
 methyl (E)-2-octenoateFL/FR
 methyl heptanoateFL/FR
 rose butanoateFL/FR
green
isoamyl salicylateFL/FR
 angelica root oilFL/FR
(+)-alpha-campholenic aldehydeFL/FR
 canarium luzonicum oilFL/FR
 cinnamyl alcoholFL/FR
 cyclamen aldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
para-dimethyl hydroquinoneFL/FR
alpha-farneseneFL/FR
alpha-farnesene isomerFL/FR
 galbanum oleoresinFL/FR
 galbanum resinoidFL/FR
(Z)-3-hexen-1-yl salicylateFL/FR
 linalool oxideFL/FR
 methyl heptine carbonateFL/FR
 methyl octine carbonateFL/FR
 nerolidolFL/FR
 oakmoss absoluteFL/FR
 phenyl acetaldehyde dimethyl acetalFL/FR
herbal
 clary sage oil franceFL/FR
 coriander seed oilFL/FR
 daucus carota fruit oilFL/FR
isodihydrolavandulalFL/FR
honey
 phenethyl phenyl acetateFL/FR
lactonic
gamma-heptalactoneFL/FR
gamma-octalactoneFL/FR
medicinal
 dimethyl benzyl carbinolFL/FR
 phenethyl salicylateFL/FR
minty
isopulegolFL/FR
(-)-isopulegolFL/FR
orris
 costus root oil CO2 extractFL
powdery
beta-naphthyl ethyl etherFL/FR
spicy
 benzyl isoeugenolFL/FR
 cassie absoluteFL/FR
 cuminaldehydeFL/FR
isoeugenyl acetateFL/FR
 ginger root oil chinaFL/FR
 levisticum officinale root oilFL/FR
2-octanolFL/FR
black pepper oilFL/FR
black pepper oil CO2 extractFL/FR
3-phenyl propyl alcoholFL/FR
terpenic
alpha-phellandreneFL/FR
tropical
alpha-amyl cinnamaldehydeFL/FR
vanilla
 ethyl vanillinFL/FR
 vanilla bean absolute (vanilla planifolia)FL/FR
 vanillyl acetateFL/FR
waxy
 butyl undecylenateFL/FR
 decanolFL/FR
 decyl acetateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 mimosa absolute franceFL/FR
 nonanolFL/FR
woody
 amyris wood oilFL/FR
isobornyl acetateFL/FR
 guaiacwood oilFL/FR
 humulus lupulus extractFL/FR
 methyl cedryl ketoneFL/FR
 patchouli oilFL/FR
 sandalwood oilFL/FR
 vetiver oil haitiFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 aldehydicFR
 animalFR
 bellodgia 
 cachet 
 chypreFR
 diffusion 
 fernFR
 floralFR
 fur 
 hair 
 my sin 
 narcissusFR
 orientalFR
 orrisFR
 patchouli oil replacerFR
 presence 
 scandal 
 tabu 
 topnotes 
 tuberoseFR
 vetiverFR
 violetFL
 vol de nuit 
 woodyFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 costus root
Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 aplotaxis lappa root oil
 aucklandia costus root oil
 auklandra costus root oil
 costus oil
 costus oil 100
 costus root oil (saussurea lappa clarke)
 saussurea costus root oil
 saussurea lappa root oil
 spiral flag root oil (saussurea lappa clarke)
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa.
PubMed: Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, India.
PubMed: Evaluation of anti-resistant activity of Auklandia (Saussurea lappa) root against some human pathogens.
PubMed: Aqueous extract of Saussurea lappa root ameliorate oxidative myocardial injury induced by isoproterenol in rats.
PubMed: Santamarin, a sesquiterpene lactone isolated from Saussurea lappa, represses LPS-induced inflammatory responses via expression of heme oxygenase-1 in murine macrophage cells.
PubMed: Larvicidal activity of medicinal plant extracts and lignan identified in Phryma leptostachya var. asiatica roots against housefly (Musca domestica L.).
PubMed: Matrix solid-phase dispersion extraction coupled with HPLC-diode array detection method for the analysis of sesquiterpene lactones in root of Saussurea lappa C.B.Clarke.
PubMed: Dehydrocostus lactone prevents mitochondrial dysfunction in osteoblastic MC3T3-E1 cells.
PubMed: A new sesquiterpene and other constituents from Saussurea lappa root.
PubMed: Antihepatotoxic activity of Saussurea lappa extract on D-galactosamine and lipopolysaccharide-induced hepatitis in mice.
PubMed: Apoptosis of DU145 human prostate cancer cells induced by dehydrocostus lactone isolated from the root of Saussurea lappa.
PubMed: Authentication of Saussurea lappa, an endangered medicinal material, by ITS DNA and 5S rRNA sequencing.
PubMed: Effects of Saussurea lappa roots extract in ethanol on leukocyte phagocytic activity, lymphocyte proliferation and interferon-gamma (IFN-gamma).
PubMed: Presence of cholinergic and calcium antagonist constituents in Saussurea lappa explains its use in constipation and spasm.
PubMed: Saussurea lappa induces G2-growth arrest and apoptosis in AGS gastric cancer cells.
PubMed: Costunolide inhibits interleukin-1beta expression by down-regulation of AP-1 and MAPK activity in LPS-stimulated RAW 264.7 cells.
PubMed: Cytotoxic sesquiterpene lactones from the root of Saussurea lappa.
PubMed: Germacrenes from fresh costus roots.
PubMed: Costunolide induces apoptosis by ROS-mediated mitochondrial permeability transition and cytochrome C release.
PubMed: Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line.
PubMed: Effect of dehydrocostus lactone and costunolide from Saussurea root on the central nervous system in mice.
PubMed: Effect of polyols on heat inactivation of Aspergillus niger van Teighem inulinase.
PubMed: Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells.
PubMed: Saussureamines A, B, C, D, and E, new anti-ulcer principles from Chinese Saussureae Radix.
PubMed: Sesquiterpenoids from costum root oil (Saussurea lappa Clarke)
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