(E,E)-farnesol
all-(E)-farnesol
 
Notes:
Flavouring ingredient Farnesol is a natural organic compound which is an acyclic sesquiterpene alcohol found as a colorless liquid. It is insoluble in water, but miscible with oils. It is the building block of most, and possibly all, acyclic sesquiterpenoids and is an important starting compound for organic synthesis. [Wikipedia]
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      Product(s):
      106-28-5 (E,E)-FARNESOL 97+% FCC
       
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Synonyms   Articles   Notes   Search
CAS Number: 106-28-5Picture of molecule3D/inchi
FDA UNII: X23PI60R17
Nikkaji Web: J5.049K
Beilstein Number: 1763926
MDL: MFCD00002918
XlogP3-AA: 4.80 (est)
Molecular Weight: 222.37142000
Formula: C15 H26 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless clear liquid (est)
Assay: 97.00 to 100.00 % sum of isomers
Food Chemicals Codex Listed: No
Specific Gravity: 0.88400 to 0.88900 @  25.00 °C.
Pounds per Gallon - (est).: 7.356 to  7.397
Refractive Index: 1.48700 to 1.49400 @  20.00 °C.
Boiling Point: 283.00 to  284.00 °C. @ 760.00 mm Hg
Boiling Point: 137.00 °C. @ 3.00 mm Hg
Vapor Pressure: 0.000370 mmHg @ 25.00 °C. (est)
Vapor Density: >1 ( Air = 1 )
Flash Point: 230.00 °F. TCC ( 110.00 °C. )
logP (o/w): 5.314 (est)
Soluble in:
 alcohol
 water, 1.287 mg/L @ 25 °C (est)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: floral
 
Odor Strength: low
 
 muguet  floral  sweet  lily  waxy  
Odor Description:
at 100.00 %. 
mild muguet floral sweet lily waxy
 
Odor and/or flavor descriptions from others (if found).
 
Bedoukian Research
(e,e)-FARNESOL ≥97.0% (sum of isomers), FCC, Kosher
Odor Description: subtle, green, floral
Used in rose and other floral compositions.
Taste Description: green
Can be used as a fresh note in sour, tart fruits such as kiwi, carambola (star fruit) and green apples.
 
 
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Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
BOC Sciences
For experimental / research use only.
(E,E)-FARNESOL 97+% FCC
Penta International
TRANS, TRANS-FARNESOL
Santa Cruz Biotechnology
For experimental / research use only.
trans,trans-Farnesol
Sigma-Aldrich: Aldrich
For experimental / research use only.
trans,trans-Farnesol 96%
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  6000 mg/kg
THERAP
27,893,1972

Dermal Toxicity:
skin-rabbit LD50 > 5000 mg/kg
27,893,1972

Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect: Sensitization
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.08 %
Category 2: Products applied to the axillae
0.11 %
Category 3: Products applied to the face/body using fingertips
0.40 %
Category 4: Products related to fine fragrance
1.20 %
 Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.60 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
Category 5D: Baby Creams, baby Oils and baby talc
Category 6: Products with oral and lip exposure
2.00 %
 Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.20 %
Category 7B: Leave-on products applied to the hair with some hand contact
Category 8: Products with significant anogenital exposure
2.00 %
Category 9: Products with body and hand exposure, primarily rinse off
5.00 %
 Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
2.50 %
Category 10B: Household aerosol/spray products
 Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
See Note %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
 Notes:
IFRA FLAVOR REQUIREMENTS:

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.

 

(1) IFRA would recommend that any material used to impart perfume or flavour in products intended for human ingestion should consist of ingredients that are in compliance with appropriate regulations for foods and food flavourings in the countries of planned distribution and, where these are lacking, with the recommendations laid down in the Code of Practice of IOFI (International Organisation of the Flavor Industry). Further information about IOFI can be found on its website (www.iofi.org).

 

(2) Category 11 includes all non-skin contact or incidental skin contact products. Due to the negligible skin contact from these types of products there is no justification for a restriction of the concentration of this fragrance ingredient in the finished product.

 
Recommendation for (E,E)-farnesol flavor usage levels up to:
  2.0000 ppm in the finished product.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 106-28-5
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 445070
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
Chemidplus: 0000106285
RTECS: JR4979000 for cas# 106-28-5
Synonyms   Articles   Notes   Search   Top
References:
 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 445070
Pubchem (sid): 135024870
Flavornet: 106-28-5
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
KEGG (GenomeNet): C01126
HMDB (The Human Metabolome Database): Search
FooDB: FDB014516
YMDB (Yeast Metabolome Database): YMDB00404
Export Tariff Code: 2905.22.0000
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Formulations/Preparations:
•biomite active ingredient 0.1670% farnesol, 0.4170% nerolidol, 0.4170% 3,7-dimethyl-6-octen-1-ol, 0.4170% geraniol •stirrup - m active ingredient 0.9720% farnesol, 0.7880% nerolidol
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
aldehydic
 adoxal (Givaudan)FL/FR
 citronellyl oxyacetaldehydeFL/FR
9-decenalFL/FR
 lily pentanalFR
 mandarine undecenalFL/FR
 muguet undecadienalFR
 nonanal (aldehyde C-9)FL/FR
(Z)-8-undecenalFR
animal
para-cresyl isobutyrateFL/FR
para-cresyl phenyl acetateFL/FR
balsamic
 linalyl cinnamateFL/FR
citrus
 benzyl anthranilateFR
 citronellyl nitrileFR
 citrus ocimenolFR
(Z)-4-decenalFL/FR
 myrmac aldehydeFR
 tetrahydromyrcenolFR
10-undecen-1-olFL/FR
floral
alpha-amyl cinnamaldehyde dimethyl acetalFL/FR
alpha-butyl cinnamaldehydeFL/FR
4-isobutyl cyclohexane propanalFR
 citronellyl ethoxalateFR
 corps popinalFR
para-cresyl propionaldehydeCS
 cumin carbinolFR
 cuminyl acetaldehydeFL/FR
 cyclamen aldehyde / methyl anthranilate schiff's baseFR
 cyclamen homoaldehydeFR
 cyclohexyl ethyl alcoholFL/FR
 cyclohexyl propanolFR
2-decalinolFR
2,5-dimethyl-2-indan methanolFR
4-ethyl cyclohexane propanalFR
 ethyl linalyl acetalFR
 floral butanalFR
 floral pyranolFR
 floral specialtyFR
 freesia acetateFR
 gardenia decaloneFR
 hawthorn ethanolFR
(Z)-4-hepten-2-yl salicylateFR
 hexyl 2-furoateFL/FR
 hydroxycitronellalFL/FR
 hydroxycitronellal / methyl anthranilate schiff's baseFR
 hydroxycitronellal diethyl acetalFL/FR
 hydroxycitronellal dimethyl acetalFL/FR
 hydroxycitronellal distillation residue distillatesFR
 hydroxycitronellal nitrileFR
 hydroxycitronellal propylene glycol acetalFL/FR
 hydroxycitronellal residueFR
 hydroxycitronellolFL/FR
 jasimiaFR
 leerallFR
 leerall / methyl anthranilate schiff's baseFR
calla lily fragranceFR
 lily of the valley specialtyFR
 lily propanolFR
 lilyallFR
 lilyall / methyl anthranilate schiff's baseFR
 lilyall substituteFR
 linalyl benzoateFL/FR
 linalyl propionateFL/FR
 linden blossom fragranceFR
 linden blossom specialtyFR
 magnolia cyclohexanolFR
 magnolia decadienalFR
 methoxycitronellalFR
 methyl citronellateFL/FR
4-methyl cyclohexane propanalFR
2-methyl octanalFL/FR
1-methyl-3-(2-methyl propyl) cyclohexanolFR
3-methyl-6-ethyl-5-octen-1-olFR
 muguet butanalFR
 muguet butanolFR
 muguet carbaldehydeFR
 muguet carbinolFL/FR
 muguet carboxaldehydeFR
 muguet ethanolFR
 muguet nitrileFR
 muguet octadienolFR
 muguet propanolFR
 muguet shiseolFL/FR
 muguet specialtyFR
3-nonanon-1-yl acetateFL/FR
 octahydro-4,7-methano-1H-indene-5-acetaldehydeFR
 octahydro-4,7-methano-1H-indene-5-acetaldehyde + 6-methyl-octahydro-4,7-methano-indene-5-carbaldehydFR
 phenethyl hexanoateFL/FR
 phenyl glycol diacetateFR
4-propyl cyclohexane propanalFR
3-(4-propyl phenyl) propionaldehyde 
alpha-terpinyl anthranilateFL/FR
 tetrahydrolinaloolFL/FR
 ylang ylang flower oilFL/FR
fruity
 methyl heptanoateFL/FR
green
 heptyl formateFL/FR
 phenyl acetaldehyde diethyl acetalFL/FR
 phenyl hexyl acetateFR
herbal
 dimethyl benzyl carbinyl formateFL/FR
marine
 ozone propanalFR
waxy
 ethyl laurateFL/FR
 hexadecanolFL/FR
(Z)-nerolidol 
woody
 hydroxycitronellal diisotridecyl acetalFR
 
For Flavor
 
No flavor group found for these
alpha-amyl cinnamaldehyde dimethyl acetalFL/FR
9-decenalFL/FR
 dimethyl benzyl carbinyl formateFL/FR
 hydroxycitronellal propylene glycol acetalFL/FR
2-methyl octanalFL/FR
(Z)-nerolidol 
 phenyl acetaldehyde diethyl acetalFL/FR
3-(4-propyl phenyl) propionaldehyde 
alpha-terpinyl anthranilateFL/FR
10-undecen-1-olFL/FR
alpha-butyl cinnamaldehydeFL/FR
aldehydic
 nonanal (aldehyde C-9)FL/FR
aromatic
para-cresyl isobutyrateFL/FR
citrus
 citronellyl oxyacetaldehydeFL/FR
(Z)-4-decenalFL/FR
fatty
 heptyl formateFL/FR
floral
 methyl citronellateFL/FR
 muguet carbinolFL/FR
 muguet shiseolFL/FR
 tetrahydrolinaloolFL/FR
 ylang ylang flower oilFL/FR
fruity
 linalyl benzoateFL/FR
 linalyl cinnamateFL/FR
 methyl heptanoateFL/FR
3-nonanon-1-yl acetateFL/FR
green
 cuminyl acetaldehydeFL/FR
 cyclohexyl ethyl alcoholFL/FR
 hexyl 2-furoateFL/FR
herbal
 linalyl propionateFL/FR
melon
 hydroxycitronellal diethyl acetalFL/FR
phenolic
para-cresyl phenyl acetateFL/FR
powdery
 hydroxycitronellolFL/FR
waxy
 adoxal (Givaudan)FL/FR
 ethyl laurateFL/FR
 hexadecanolFL/FR
 hydroxycitronellalFL/FR
 hydroxycitronellal dimethyl acetalFL/FR
 mandarine undecenalFL/FR
 phenethyl hexanoateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 aldehydicFR
 floralFR
 lilyFR
 lily of the valleyFR
 waxy 
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 ambrette seed concrete @ 2.16%
Data  GC  Search Trop  Picture
 ambrette seed oil @ 3.50%
Data  GC  Search Trop  Picture
 boronia absolute @ 0.08%
Data  GC  Search Trop  Picture
 cabocla flower oil brazil @ 0.50%
Data  GC  Search Trop  Picture
 champaca concrete @ 0.20%
Data  GC  Search Trop  Picture
 cinnamon ceylon cinnamon leaf
Search Trop  Picture
 clove bud oil @ 1.08%
Data  GC  Search Trop  Picture
 clove leaf oil @ 0.61%
Data  GC  Search Trop  Picture
 clove stem oil india @ 0.69%
Data  GC  Search Trop  Picture
 couroupita guianensis aubl. flower oil brazil @ 16.10%
Data  GC  Search Trop  Picture
 curry fruit oil india @ <0.05%
Data  GC  Search Trop  Picture
 curry leaf oil india @ 0.20%
Data  GC  Search Trop  Picture
 geranium rose-scented oil (pelargonium spp.) cuba @ 0.20%
Data  GC  Search Trop  Picture
 ginger root oil CO2 extract @ 0.88%
Data  GC  Search Trop  Picture
 guava leaf oil cuba @ 0.20%
Data  GC  Search Trop  Picture
 jasmin absolute china (from concrete) @ 0.09%
Data  GC  Search Trop  Picture
 jasmin sambac absolute egypt @ 1.30%
Data  GC  Search Trop  Picture
 palmarosa oil @ 1.90%
Data  GC  Search Trop  Picture
 rose oil otto bulgaria @ 1.98%
Data  GC  Search Trop  Picture
 skimmia laureola oil @ 0.7%
Data  GC  Search Trop  Picture
 thevetia peruviana (pers.) k. schum. flower oil brazil @ 0.10%
Data  GC  Search Trop  Picture
 ylang ylang oil @ 0.84%
Data  GC  Search Trop  Picture
 ylang ylang oil CO2 extract @ 1.39%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
2,6-di-trans-farnesol
2,6,10-dodecatrien-1-ol, 3,7,11-trimethyl-, (2E,6E)-
2,6,10-dodecatrien-1-ol, 3,7,11-trimethyl-, (E,E)-
(2-trans,6-trans)-farnesol
(2E,6E)-farnesol
(E,E)-2,6-farnesol
(E)-farnesol
2-trans,6-trans-farnesol
all-(E)-farnesol
all-trans-farnesol
trans, trans-farnesol
trans,trans-farnesol
(2E,6E)-3,7,11-trimethyl-1-dodeca-2,6,10-trienol
(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
(E,E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
trans,trans-3,7,11-trimethyl-2,6,10-dodecatrien-1-ol
(2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trien-1-ol
3,7,11-trimethyldodeca-2-trans,6-trans,10-trien-1-ol
(2-trans,6-trans)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol
Synonyms   Articles   Notes   Search   Top
Articles:
Info: Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.)
PubMed: Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed: Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
PubMed: Essential oil composition and antimicrobial activities of two closely related species, Alpinia mutica Roxb. and Alpinia latilabris Ridl., from Peninsular Malaysia.
PubMed: Gold(I) as an artificial cyclase: short stereodivergent syntheses of (-)-epiglobulol and (-)-4β,7α- and (-)-4α,7α-aromadendranediols.
PubMed: Assessment of the antioxidant and antiproliferative effects of sesquiterpenic compounds in in vitro Caco-2 cell models.
PubMed: [Tobacco--once a medicinal plant. Does it contain substances with medicinal properties?].
PubMed: Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.
PubMed: Chemical composition and in vitro antimicrobial and antioxidant activities of Citrus aurantium l. flowers essential oil (Neroli oil).
PubMed: Characterization of essential oil from Citrus aurantium L. flowers: antimicrobial and antioxidant activities.
PubMed: Determination of E,E-farnesol in Makgeolli (rice wine) using dynamic headspace sampling and stir bar sorptive extraction coupled with gas chromatography-mass spectrometry.
PubMed: Study of trans-trans farnesol effect on hyphae formation by Yarrowia lipolytica.
PubMed: β-ionone induces cell cycle arrest and apoptosis in human prostate tumor cells.
PubMed: Engineered heterologous FPP synthases-mediated Z,E-FPP synthesis in E. coli.
PubMed: Chemical composition and antifungal activity of Matricaria recutita flower essential oil against medically important dermatophytes and soil-borne pathogens.
PubMed: Specific involvement of two amino acid residues in cis-nerolidol binding to odorant-binding protein 5 AlinOBP5 in the alfalfa plant bug, Adelphocoris lineolatus (Goeze).
PubMed: A convergent stereocontrolled total synthesis of (-)-terpestacin.
PubMed: Comparative study of the chemical composition and biological activities of Magnolia grandiflora and Magnolia virginiana flower essential oils.
PubMed: Quorum sensing activity in Ophiostoma ulmi: effects of fusel oils and branched chain amino acids on yeast-mycelial dimorphism.
PubMed: Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis).
PubMed: Effect of exogenous administration of Candida albicans autoregulatory alcohols in a murine model of hematogenously disseminated candidiasis.
PubMed: Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed: Drimenol: A versatile synthon for compounds with trans-drimane skeleton.
PubMed: Influences of trans-trans farnesol, a membrane-targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed-species oral biofilms.
PubMed: Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.
PubMed: Application of a multidimensional gas chromatography system with simultaneous mass spectrometric and flame ionization detection to the analysis of sandalwood oil.
PubMed: Variation in volatile leaf oils of eleven eucalyptus species harvested from korbous arboreta (Tunisia).
PubMed: The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species.
PubMed: Candida species extracellular alcohols: production and effect in sessile cells.
PubMed: Production of geranylgeraniol on overexpression of a prenyl diphosphate synthase fusion gene in Saccharomyces cerevisiae.
PubMed: Effect of Matricaria chamomilla L. flower essential oil on the growth and ultrastructure of Aspergillus niger van Tieghem.
PubMed: Determination of the volatile composition in essential oil of Descurainia sophia (L.) Webb ex Prantl (Flixweed) by gas chromatography/mass spectrometry (GC/MS).
PubMed: Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography.
PubMed: Flowerhead volatile oil composition of soilless culture-grown Chrysanthemum balsamita L.
PubMed: Quantification approach for assessment of sparkling wine volatiles from different soils, ripening stages, and varieties by stir bar sorptive extraction with liquid desorption.
PubMed: Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols.
PubMed: Optimisation of stir bar sorptive extraction and liquid desorption combined with large volume injection-gas chromatography-quadrupole mass spectrometry for the determination of volatile compounds in wines.
PubMed: Synthesis of cordiaquinones B, C, J, and K on the basis of a bioinspired approach and the revision of the relative stereochemistry of cordiaquinone C.
PubMed: Secretion of E,E-farnesol and biofilm formation in eight different Candida species.
PubMed: Morphogenesis control in Candida albicans and Candida dubliniensis through signaling molecules produced by planktonic and biofilm cells.
PubMed: Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry.
PubMed: The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes.
PubMed: Analysis of the essential oil of Grindelia discoidea.
PubMed: Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways.
PubMed: Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design.
PubMed: Determination of terpenes in tequila by solid phase microextraction-gas chromatography-mass spectrometry.
PubMed: A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol.
PubMed: Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke.
PubMed: Volatile constituents of redblush grapefruit (Citrus paradisi) and pummelo (Citrus grandis) peel essential oils from Kenya.
PubMed: Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog.
PubMed: Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum.
PubMed: Responses to sex pheromone and plant odours by olfactory receptor neurons housed in sensilla auricillica of the codling moth, Cydia pomonella (Lepidoptera: Tortricidae).
PubMed: Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.
PubMed: Comprehensive two-dimensional gas chromatography with flame ionization and time-of-flight mass spectrometry detection: qualitative and quantitative analysis of West Australian sandalwood oil.
PubMed: Farnesol-DMPC phase behaviour: a (2)H-NMR study.
PubMed: Quorum sensing in Candida albicans: probing farnesol's mode of action with 40 natural and synthetic farnesol analogs.
PubMed: Detection of farnesyl diphosphate accumulation in yeast ERG9 mutants.
PubMed: The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.
PubMed: Squalestatin 1-inducible expression of rat CYP2B: evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor.
PubMed: African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol.
PubMed: Alendronate inhibits invasion of PC-3 prostate cancer cells by affecting the mevalonate pathway.
PubMed: Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol.
PubMed: Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
PubMed: Metabolism of farnesyl diphosphate in tobacco BY-2 cells treated with squalestatin.
PubMed: Synthesis and biological evaluation of the geometric farnesylated analogues of the a-factor mating peptide of Saccharomyces cerevisiae.
PubMed: Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability.
PubMed: Sex pheromone mimicry in the early spider orchid (ophrys sphegodes): patterns of hydrocarbons as the key mechanism for pollination by sexual deception.
PubMed: Farnesyl anthranilate suppresses the growth, in vitro and in vivo, of murine B16 melanomas.
PubMed: Pleiotropic effects of statins in atherosclerosis and diabetes.
PubMed: Comparison of headspace techniques for sampling volatile natural products in a dynamic system.
PubMed: Direct vascular effects of HMG-CoA reductase inhibitors.
PubMed: Studies on the Synthesis of Elegan-Type Linear Diterpenes: The Efficient Total Syntheses of Eleganolone, Eleganolone Acetate, Elegandiol, Eleganonal, and Epoxyeleganolone
PubMed: Lovastatin induces apoptosis by inhibiting mitotic and post-mitotic events in cultured mesangial cells.
PubMed: Activators of the nuclear hormone receptors PPARalpha and FXR accelerate the development of the fetal epidermal permeability barrier.
PubMed: Pharmacological control of the mevalonate pathway: effect on arterial smooth muscle cell proliferation.
PubMed: Male sex pheromone of a giant danaine butterfly,Idea leuconoe.
PubMed: Identification and characterization of geranylgeraniol kinase and geranylgeranyl phosphate kinase from the Archaebacterium Sulfolobus acidocaldarius.
PubMed: Effects of farnesol on the thermotropic behavior of dimyristoylphosphatidylcholine.
PubMed: Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: effect of phosphatidylcholine.
PubMed: Differences in sensitivity to farnesol toxicity between neoplastically- and non-neoplastically-derived cells in culture.
PubMed: Requirement for isoprenoid-dependent posttranslational modifications in the cell-cycle progression of human breast-cancer cells.
PubMed: Growth inhibition of leukemia cell line CEM-C1 by farnesol: effects of phosphatidylcholine and diacylglycerol.
PubMed: Chemical analysis of temporal gland secretions collected from an Asian bull elephant during a four-month musth episode.
PubMed: The conformation of dolichol.
PubMed: Chemosensory responses in two species of elephants to constituents of temporal gland secretion and musth urine.
PubMed: Odor mimetism? : Key substances inOphrys lutea-Andrena pollination relationship (Orchidaceae: Andrenidae).
PubMed: Total synthesis of chain-length-uniform dolichyl phosphates and their fitness to accept hexoses in the enzymatic formation of lipoglycans.
PubMed: Constituents of temporal gland secretion of the African elephant,Loxodonta africana.
PubMed: The Nasonov pheromone of the honeybeeApis mellifera L. (Hymenoptera, Apidae). Part II. Bioassay of the components using foragers.
PubMed: Photosynthetic pigments of green sulfur bacteria. The esterifying alcohols of bacteriochlorophylls c from Chlorobium limicola.
PubMed: Levels of short-chain fatty acids and of abscisic acid in water-stressed and non-stressed leaves and their effects on stomata in epidermal strips and excised leaves.
PubMed: Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes.
PubMed: Comparison between Biosynthesis of ent-Kaurene in Germinating Tomato Seeds and Cell Suspension Cultures of Tomato and Tobacco.
PubMed: Detection and preliminary identification of endogenous antitranspirants in water-stressed Sorghum plants.
PubMed: Biosynthesis of trans, trans- and cis, trans-farnesols by soluble enzymes from tissue cultures of Andrographis paniculata.
PubMed: All-trans-farnesol: a naturally occurring antitranspirant?
PubMed: Synthesis of cecropia juvenile hormone from trans,trans-farnesol.
PubMed: Lipid metabolism in helminth parasites--VI. Synthesis of 2-cis,6-trans farnesol by Hymenolepis diminuta (Cestoda).
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