beta-elemene
(1R,2R,4S)-1-methyl-2,4-di(prop-1-en-2-yl)-1-vinylcyclohexane
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
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      Product(s):
      33880-83-0 Elemene 95%
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email: Technical Services
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      Product(s):
      05-02100 BETA-ELEMENE
      05-02105 BETA-ELEMENE NATURAL
       
Synonyms   Articles   Notes   Search
CAS Number: 33880-83-0Picture of molecule3D/inchi
Other(deleted CASRN): 100762-52-5
ECHA EINECS - REACH Pre-Reg: 251-713-0
Nikkaji Web: J308.554F
XlogP3-AA: 6.10 (est)
Molecular Weight: 204.35628000
Formula: C15 H24
NMR Predictor: Predict (works with chrome or firefox)
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless to yellow clear liquid (est)
Assay: 92.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 251.00 to  253.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.027600 mmHg @ 25.00 °C.
Flash Point: 209.00 °F. TCC ( 98.30 °C. ) (est)
logP (o/w): 5.772 (est)
Soluble in:
 alcohol
 water, 0.01172 mg/L @ 25 °C (est)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: herbal
 
 herbal  waxy  fresh  
Odor Description:
at 100.00 %. 
herbal waxy fresh
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
BOC Sciences
For experimental / research use only.
Elemene 95%
Isobionics
Natural Beta Elemene
Odor: characteristic
Use: Beta Eelemene can be used as a building block in the flavour and fragrance industry Isobionics offers Beta Elemene with a minimal purity of 98% Appearance: clear colourless liquid
Penta International
BETA-ELEMENE NATURAL
Penta International
BETA-ELEMENE
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for beta-elemene usage levels up to:
  4.0000 % in the fragrance concentrate.
 
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 33880-83-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 9859094
National Institute of Allergy and Infectious Diseases: Data
 (1R,2R,4S)-1-ethenyl-1-methyl-2,4-di(prop-1-en-2-yl)cyclohexane
Chemidplus: 0033880830
Synonyms   Articles   Notes   Search   Top
References:
 (1R,2R,4S)-1-ethenyl-1-methyl-2,4-di(prop-1-en-2-yl)cyclohexane
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 9859094
Pubchem (sid): 134998583
Flavornet: 33880-83-0
Pherobase: View
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
HMDB (The Human Metabolome Database): Search
FooDB: FDB014577
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
aldehydic
 lily pentanalFR
N/i-tridecanalFR
citrus
beta-sinensalFL/FR
floral
 citronellalFL/FR
 citronellyl phenyl acetateFL/FR
 gelsone (IFF)FL/FR
 geranyl hexanoateFL/FR
alpha-hexyl cinnamaldehydeFL/FR
 octyl acetateFL/FR
(E)-2-undecen-1-olFL/FR
fruity
 acetaldehyde dihexyl acetalFL/FR
green
(E)-2-hexen-1-yl hexanoateFL/FR
herbal
 butyl levulinateFL/FR
(-)-alpha-cubebene 
spicy
 bayberry fragranceFR
 pimenta acris leaf oilFL/FR
woody
 sandal cyclopentaneFR
 
For Flavor
 
No flavor group found for these
(-)-alpha-cubebene 
beta-sinensalFL/FR
(E)-2-undecen-1-olFL/FR
floral
 citronellalFL/FR
 citronellyl phenyl acetateFL/FR
fruity
 geranyl hexanoateFL/FR
green
 acetaldehyde dihexyl acetalFL/FR
 gelsone (IFF)FL/FR
(E)-2-hexen-1-yl hexanoateFL/FR
herbal
 butyl levulinateFL/FR
spicy
 pimenta acris leaf oilFL/FR
waxy
alpha-hexyl cinnamaldehydeFL/FR
 octyl acetateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 allamanda cathartica linn. flower oil brazil @ 0.50%
Data  GC  Search Trop  Picture
 allspice plant
Search Trop  Picture
 amyris wood oil @ 0.10%
Data  GC  Search Trop  Picture
 angelica seed oil CO2 extract @ trace%
Data  GC  Search Trop  Picture
 anise seed oil
Search Trop  Picture
 anise seed oil star china @ 0.04%
Data  GC  Search Trop  Picture
 anise star anise fruit
Search Trop  Picture
 armoise oil morocco @ 1.7%
Data  GC  Search Trop  Picture
 baccharis coridifolia oil argentina @ 1.20%
Data  GC  Search Trop  Picture
 backhousia citriodora f. muell. leaf oil @ 0.10%
Data  GC  Search Trop  Picture
 basil absolute sweet @ 0.48%
Data  GC  Search Trop  Picture
 basil flower oil sweet @ 0.73%
Data  GC  Search Trop  Picture
 basil leaf oil sweet (ocimum basilicum) @ 0.90%
Data  GC  Search Trop  Picture
 basil oil
Search Trop  Picture
 basil oil CO2 sweet @ trace%
Data  GC  Search Trop  Picture
 basil oil sweet @ 0.96%
Data  GC  Search Trop  Picture
 basil oil sweet egypt @ 0.11%
Data  GC  Search Trop  Picture
 basil oil sweet poland @ 0.86%
Data  GC  Search Trop  Picture
 basil oil var. glabratum turkey @ 0.30%
Data  GC  Search Trop  Picture
 basil plant
Search Trop  Picture
 basil shoot oil
Search Trop  Picture
 bay laurel leaf oil
Search Trop  Picture
 bay laurel plant
Search Trop  Picture
 bay leaf oil @ 0.00-0.20%
Data  GC  Search Trop  Picture
 bergamot mint oil @ 0.0-0.3%
Data  GC  Search Trop  Picture
 burdock root
Search Trop  Picture
 cabocla flower oil brazil @ 1.70%
Data  GC  Search Trop  Picture
 cajuput oil vietnam @ 0.3%
Data  GC  Search Trop  Picture
 calamus leaf oil @ 0.79%
Data  GC  Search Trop  Picture
 calamus rhizome oil @ 0.48%
Data  GC  Search Trop  Picture
 calamus root oil @ 0.29%
Data  GC  Search Trop  Picture
 calamus root oil mongolia @ 0.50%
Data  GC  Search Trop  Picture
 callitris intratropica wood oil australia @ 0.50%
Data  GC  Search Trop  Picture
 camel grass oil @ trace%
Data  GC  Search Trop  Picture
 cananga leaf oil @ 1.4%
Data  GC  Search Trop  Picture
 caraway oil
Search Trop  Picture
 caraway seed oil
Search Trop  Picture
 carrot plant
Search Trop  Picture
 carrot plant
Search Trop  Picture
 cascarilla bark oil @ 1.63%
Data  GC  Search Trop  Picture
 cassis bud oil @ trace-0.14%
Data  GC  Search Trop  Picture
 cedrela wood oil @ 0.10%
Data  GC  Search Trop  Picture
 celery leaf
Search Trop  Picture
 celery leaf oil
Search Trop  Picture
 celery seed
Search Trop  Picture
 celery seed oil
Search Trop  Picture
 celery seed oil CO2 extract india @ 0.04%
Data  GC  Search Trop  Picture
 celery seed oil india @ 0.07%
Data  GC  Search Trop  Picture
 champaca concrete @ 0.58%
Data  GC  Search Trop  Picture
 cinnamomum fragrans baillon leaf oil madagascar @ trace%
Data  GC  Search Trop  Picture
 cinnamon ceylon cinnamon leaf
Search Trop  Picture
 cinnamon leaf oil ceylon @ 0.34%
Data  GC  Search Trop  Picture
 citronella oil ceylon @ 1.10%
Data  GC  Search Trop  Picture
 citronella oil china @ 2.80%
Data  GC  Search Trop  Picture
 citronella oil java @ 1.96%
Data  GC  Search Trop  Picture
 clary sage oil spain @ 0.43%
Data  GC  Search Trop  Picture
 croton cajucara benth. leaf oil brazil @ 0.70%
Data  GC  Search Trop  Picture
 croton flavens l. (welensali) leaf oil curacao @ 0.80%
Data  GC  Search Trop  Picture
 cumin seed
Search Trop  Picture
 curcuma amada roxb. rhizome oil india @ 2.80%
Data  GC  Search Trop  Picture
 curry fruit oil india @ <0.05%
Data  GC  Search Trop  Picture
 curry leaf oil india @ 0.20%
Data  GC  Search Trop  Picture
 curry wood leaf oil australia @ 0.60%
Data  GC  Search Trop  Picture
 dill seed
Search Trop  Picture
 echinophora cinerea oil iran @ 0.10%
Data  GC  Search Trop  Picture
 galangal root oil @ 0.30%
Data  GC  Search Trop  Picture
 geranium rose-scented oil (pelargonium spp.) cuba @ 0.70%
Data  GC  Search Trop  Picture
 ginger rhizome
Search Trop  Picture
 ginger rhizome oil
Search Trop  Picture
 ginger root oil brazil @ 0.90%
Data  GC  Search Trop  Picture
 ginger root oil china @ 0.81%
Data  GC  Search Trop  Picture
 ginger root oil CO2 extract australia @ 0.20%
Data  GC  Search Trop  Picture
 grapefruit oil california @ 0.03%
Data  GC  Search Trop  Picture
 horsemint shoot
Search Trop  Picture
 hyptis spicigera lam. oil mali @ 0.10-0.20%
Data  GC  Search Trop  Picture
 hyssop plant
Search Trop  Picture
 juniper berry oil @ 1.10%
Data  GC  Search Trop  Picture
 kachur oil @ 3.30%
Data  GC  Search Trop  Picture
 laurel leaf oil turkey @ 0.60%
Data  GC  Search Trop  Picture
 lemon balm shoot
Search Trop  Picture
 lemon oil
Search Trop  Picture
 lemongrass oil @ 0.13%
Data  GC  Search Trop  Picture
 lemongrass oil @ 0.15%
Data  GC  Search Trop  Picture
 lime oil CO2 extract mexico @ 0.13%
Data  GC  Search Trop  Picture
 lime oil distilled mexico @ trace%
Data  GC  Search Trop  Picture
 lime oil distilled peru @ 0.06%
Data  GC  Search Trop  Picture
 lime oil expressed florida @ 0.1%
Data  GC  Search Trop  Picture
 lovage root
Search Trop  Picture
 mandarin
Search Trop  Picture
 mandarin fruit
Search Trop  Picture
 mandarin oil uruguay @ 0.01%
Data  GC  Search Trop  Picture
 manuka var. eximium oil australia @ 0.10%
Data  GC  Search Trop  Picture
 manuka var. scoparium oil new zealand @ 0.55%
Data  GC  Search Trop  Picture
 marsypianthes chamaedrys (vahl) kuntze oil brazil @ 2.50%
Data  GC  Search Trop  Picture
 mikan peel oil @ trace%
Data  GC  Search Trop  Picture
 mikania cordata (burm. f.) b.l. robinson var. cordata leaf oil france @ 2.10%
Data  GC  Search Trop  Picture
 mint
Search Trop  Picture
 ocimum gratissimum l. oil brazil @ 2.03%
Data  GC  Search Trop  Picture
 orange
Search Trop  Picture
 orange bigarade oil @ 0.31%
Data  GC  Search  Picture
 orange fruit
Search Trop  Picture
 orange peel oil bitter china @ trace%
Data  GC  Search Trop  Picture
 orange peel oil bitter italy @ 0.01%
Data  GC  Search Trop  Picture
 orange pericarp oil
Search Trop  Picture
 oregano plant
Search Trop  Picture
 oregano shoot oil
Search Trop  Picture
 orthodon dianthera maxim. oil vietnam @ 0.20%
Data  GC  Search Trop  Picture
 palmarosa oil @ 0.10%
Data  GC  Search Trop  Picture
 parsley leaf
Search Trop  Picture
 parsley leaf oil @ 1.59%
Data  GC  Search Trop  Picture
 parsley leaf oil cuba @ 0.61%
Data  GC  Search Trop  Picture
 patchouli oil @ 6.08%
Data  GC  Search Trop  Picture
 pepper black pepper fruit
Search Trop  Picture
 pepper black pepper fruit oil
Search Trop  Picture
 pepper oil black india @ trace%
Data  GC  Search Trop  Picture
 pepper tree berry oil @ 0.52%
Data  GC  Search Trop  Picture
 pepper tree leaf oil @ 0.01%
Data  GC  Search Trop  Picture
 peppermint oil CO2 extract @ 0.90%
Data  GC  Search Trop  Picture
 persea americana mill. fruit oil cuba @ trace%
Data  GC  Search Trop  Picture
 petitgrain combava oil @ trace%
Data  GC  Search  Picture
 petitgrain grapefruit oil @ trace%
Data  GC  Search Trop  Picture
 petitgrain mandarin oil @ 1.28%
Data  GC  Search Trop  Picture
 petitgrain sweet oil @ 0.03%
Data  GC  Search  Picture
 phlomis fruticosa l. flower oil greece @ 0.30%
Data  GC  Search Trop  Picture
 phoebe oil brazil @ 0.44%
Data  GC  Search Trop  Picture
 pine needle oil dwarf @ 4.81%
Data  GC  Search Trop  Picture
 pinus sylvestris l. needle oil estonia @ 0.30%
Data  GC  Search Trop  Picture
 piper cernum vell. var. cernum yuncker leaf oil brazil @ 0.60%
Data  GC  Search Trop  Picture
 plectranthus glandulosus hook f. leaf oil cameroon @ 0.10%
Data  GC  Search Trop  Picture
 polyalthia australis (benth.) jessup leaf oil australia @ 1.00%
Data  GC  Search Trop  Picture
 potato
Search Trop  Picture
 ravintsara leaf oil @ 0.63%%
Data  GC  Search  Picture
 rose oil otto bulgaria @ 0.08%
Data  GC  Search Trop  Picture
 rosemary sap
Search Trop  Picture
 rosemary shoot
Search Trop  Picture
 salvia atropatana bunge oil iran @ 1.40%
Data  GC  Search Trop  Picture
 salvia officinalis seed oil tunisia @ 0.16%
Data  GC  Search Trop  Picture
 salvia sclarea oil @ 0.35%
Data  GC  Search Trop  Picture
 savin oil @ 0.62%
Data  GC  Search Trop  Picture
 sideritis montana l. oil bulgaria @ 2.00%
Data  GC  Search Trop  Picture
 sideritis scardica l. oil bulgaria @ 0.50%
Data  GC  Search Trop  Picture
 spearmint leaf
Search Trop  Picture
 spearmint oil
Search Trop  Picture
 spearmint oil america @ 0.06-0.23%
Data  GC  Search Trop  Picture
 sugandha kokila berry oil @ 0.30%
Data  GC  Search Trop  Picture
 tamarind fruit oil
Search Trop  Picture
 tamarind seed oil
Search Trop  Picture
 tanacetum annum l. oil marocco @ 0.20%
Data  GC  Search Trop  Picture
 tansy oil marocco @ 0.40%
Data  GC  Search Trop  Picture
 thevetia peruviana (pers.) k. schum. flower oil brazil @ 0.50%
Data  GC  Search Trop  Picture
 turmeric root oil vietnam @ 0.05%
Data  GC  Search Trop  Picture
 valerian root oil @ 0.1-0.4%
Data  GC  Search Trop  Picture
 valerian root oil CO2 extract china @ 0.07%
Data  GC  Search Trop  Picture
 vassoura oil @ 1.60%
Data  GC  Search Trop  Picture
 water mint shoot
Search Trop  Picture
 xylopia aromatica (lam.) mart. leaf oil cuba @ 0.20%
Data  GC  Search Trop  Picture
 yarrow leaf oil @ 0.60%
Data  GC  Search Trop  Picture
 yarrow oil @ trace%
Data  GC  Search Trop  Picture
 yarrow oil greece @ trace%
Data  GC  Search Trop  Picture
 yuzu leaf oil @ 0.19-0.39%
Data  GC  Search Trop  Picture
 zanthoxylum bracchyacanthum l. leaf oil australia @ 0.10%
Data  GC  Search Trop  Picture
 zanthoxylum nitidum l. leaf oil australia @ 2.00%
Data  GC  Search Trop  Picture
 zanthoxylum ovalifolium l. leaf oil australia @ 0.60%
Data  GC  Search Trop  Picture
 zinnia elegans jacq. flower oil brazil @ 1.70%
Data  GC  Search Trop  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
(1alpha,2beta,4beta)-1-ethenyl-1-methyl-2,4-bis(1-methyl ethenyl) cyclohexane
(1R,2R,4S)-1-ethenyl-1-methyl-2,4-bis(1-methyl ethenyl) cyclohexane
(1R,2R,4S)-1-ethenyl-1-methyl-2,4-di(prop-1-en-2-yl)cyclohexane
(1alpha,2,4)-1-methyl-2,4-bis(methyl vinyl)-1-vinyl cyclohexane
(±)-b-elemene
(1R,2R,4S)-1-methyl-2,4-di(prop-1-en-2-yl)-1-vinylcyclohexane
b-elemene
 cyclohexane, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-, (1R,2R,4S)-
rel-(1R,2R,4S)-2,4-diisopropenyl-1-methyl-1-vinylcyclohexane
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Isolation of jasmonate-induced sesquiterpene synthase of rice: Product of which has an antifungal activity against Magnaporthe oryzae.
PubMed: In vitro antibacterial activity of Libanotis montana essential oil in combination with conventional antibiotics.
PubMed: Chemical compositions and antimicrobial activity of the essential oils of Hornstedtia havilandii (Zingiberaceae).
PubMed: β-elemene reverses the drug resistance of lung cancer A549/DDP cells via the mitochondrial apoptosis pathway.
PubMed: More insight into the chemical composition of Greek propolis; differences and similarities with Turkish propolis.
PubMed: β-Elemene inhibits the metastasis of B16F10 melanoma cells by downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9.
PubMed: Chemical composition, antimicrobial and antioxidant activities of essential oil from Ampelopsis megalophylla.
PubMed: Chemical composition of essential oils from the leaves and stem barks of Vietnamese species of Polyalthia harmandiiPolyalthia jucunda and Polyalthia thorelii.
PubMed: Constituents of essential oils from the leaves, stem barks and resins of Canarium parvum Leen., and Canarium tramdenanum Dai et Yakovl. (Burseracea) grown in Vietnam.
PubMed: The effect of beta-elemene on alpha-tubulin polymerization in human hepatoma HepG2 cells.
PubMed: Essential oils composition of croton species from the Amazon.
PubMed: Essential oil composition of Aegle marmelos (L.) Correa: chemotypic and seasonal variations.
PubMed: β-Elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter.
PubMed: The effects of β-elemene on the expression of mTOR, HIF-1A, survivin in lung adenocarcinoma A549 cell.
PubMed: Quantitative Analysis and Discrimination of Steamed and Non-Steamed Rhizomes of Curcuma wenyujin by GC-MS and HPLC.
PubMed: [Synergistic effect of beta-elemene injection combined paclitaxel injection on human breast cancer MB-468 cells: an in vitro study].
PubMed: Formulation design, preparation, and in vitro and in vivo characterizations of β-Elemene-loaded nanostructured lipid carriers.
PubMed: [Potential applications of beta-elemene in anti-atherosclerosis and anti-restenosis].
PubMed: β-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK.
PubMed: Zedoary oil (Ezhu You) inhibits proliferation of AGS cells.
PubMed: 13,14-bis(cis-3,5-dimethyl-1-piperazinyl)-β-elemene, a novel β-elemene derivative, shows potent antitumor activities via inhibition of mTOR in human breast cancer cells.
PubMed: Chemical composition and antimicrobial activity of three essential oils from Curcuma wenyujin.
PubMed: β-elemene decreases cell invasion by upregulating E-cadherin expression in MCF-7 human breast cancer cells.
PubMed: β -Elemene-Attenuated Tumor Angiogenesis by Targeting Notch-1 in Gastric Cancer Stem-Like Cells.
PubMed: Characterization of Chemical Composition of Pericarpium Citri Reticulatae Volatile Oil by Comprehensive Two-Dimensional Gas Chromatography with High-Resolution Time-of-Flight Mass Spectrometry.
PubMed: The cytotoxic effect of β-elemene against malignant glioma is enhanced by base-excision repair inhibitor methoxyamine.
PubMed: Chemical composition and anti-Trypanosoma cruzi activity of essential oils obtained from leaves of Xylopia frutescens and X. laevigata (Annonaceae).
PubMed: The Role of E3 Ubiquitin Ligase Cbl Proteins in β-Elemene Reversing Multi-Drug Resistance of Human Gastric Adenocarcinoma Cells.
PubMed: [Treatment of hepatic cancer in mice by beta-elemene combined DC/Dribble vaccine: an immune mechanism research].
PubMed: Analysis of Cleistopholis patens leaf and trunk bark oils using combined GC- flame ionisation detection, GC-retention index, GC-MS and (13) C-NMR.
PubMed: Phytochemical diversity of Murraya koenigii (L.) Spreng. from Western Himalaya.
PubMed: β-Elemene promotes cisplatin-induced cell death in human bladder cancer and other carcinomas.
PubMed: Beta-elemene blocks epithelial-mesenchymal transition in human breast cancer cell line MCF-7 through Smad3-mediated down-regulation of nuclear transcription factors.
PubMed: Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells.
PubMed: β-Elemene and taxanes synergistically induce cytotoxicity and inhibit proliferation in ovarian cancer and other tumor cells.
PubMed: Chemical composition and anticancer, antiinflammatory, antioxidant and antimalarial activities of leaves essential oil of Cedrelopsis grevei.
PubMed: [The pharmacokinetics of long-circulating beta-elemene liposomes].
PubMed: Sensitization of lung cancer cells to cisplatin by β-elemene is mediated through blockade of cell cycle progression: antitumor efficacies of β-elemene and its synthetic analogs.
PubMed: Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations.
PubMed: [Study on the chemical components, antimicrobial and antitumor activities of the essential oil from the leaves of Zanthoxylum avicennae].
PubMed: Enhancement of cisplatin-induced apoptosis by β-elemene in resistant human ovarian cancer cells.
PubMed: Anticancer activity of β-Elemene and its synthetic analogs in human malignant brain tumor cells.
PubMed: Anti-Lung-Cancer Activity and Liposome-Based Delivery Systems of β-Elemene.
PubMed: Antimicrobial activity of selected essential oils against cariogenic bacteria.
PubMed: β-elemene inhibits the proliferation of T24 bladder carcinoma cells through upregulation of the expression of Smad4.
PubMed: Chemotaxonomical markers in essential oil of Murraya koenigii.
PubMed: Synergistic effects of Endostar combined with β-elemene on malignant ascites in a mouse model.
PubMed: Systematic review of β-elemene injection as adjunctive treatment for lung cancer.
PubMed: Identification of insecticidal constituents of the essential oil of Curcuma wenyujin rhizomes active against Liposcelis bostrychophila Badonnel.
PubMed: Tangy scent in Toona sinensis (Meliaceae) leaflets: isolation, functional characterization, and regulation of TsTPS1 and TsTPS2, two key terpene synthase genes in the biosynthesis of the scent compound.
PubMed: Study on the volatile oil contents of Annona glabra L., Annona squamosa L., Annona muricata L. and Annona reticulata L., from Vietnam.
PubMed: Chemical composition and biological activities of the essential oils from Duguetia lanceolata St. Hil. barks.
PubMed: β-elemene induces glioma cell apoptosis by downregulating survivin and its interaction with hepatitis B X-interacting protein.
PubMed: β-Elemene induces apoptosis in human renal-cell carcinoma 786-0 cells through inhibition of MAPK/ERK and PI3K/Akt/ mTOR signalling pathways.
PubMed: Furanodiene induces endoplasmic reticulum stress and presents antiproliferative activities in lung cancer cells.
PubMed: β-elemene acts as an antitumor factor and downregulates the expression of survivin, Bcl-xL and Mta-1.
PubMed: Chemical composition, antimicrobial, antioxidant and cytotoxic activity of the essential oil from the leaves of Acanthopanax leucorrhizus (Oliv.) Harms.
PubMed: Relation between chemical composition or antioxidant activity and antihypertensive activity for six essential oils.
PubMed: β-elemene effectively suppresses the growth and survival of both platinum-sensitive and -resistant ovarian tumor cells.
PubMed: Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review.
PubMed: Differences in the volatile compositions of ginseng species (Panax sp.).
PubMed: Volatiles from Michelia champaca flower: comparative analysis by simultaneous distillation-extraction and solid phase microextraction.
PubMed: HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis.
PubMed: Natural product studies of U.S. endangered plants: volatile components of Lindera melissifolia (Lauraceae) repel mosquitoes and ticks.
PubMed: β-Elemene radiosensitizes lung cancer A549 cells by enhancing DNA damage and inhibiting DNA repair.
PubMed: Evaluation of the antinociceptive, anti-inflammatory and gastric antiulcer activities of the essential oil from Piper aleyreanum C.DC in rodents.
PubMed: Reversion of multidrug resistance in a chemoresistant human breast cancer cell line by β-elemene.
PubMed: Potential role of β-elemene on histone H1 in the H22 ascites hepatoma cell line.
PubMed: Volatiles from Magnolia grandiflora flowers: comparative analysis by simultaneous distillation-extraction and solid phase microextraction.
PubMed: The leaf essential oils of five Vietnamese Desmos species (Annonaceae).
PubMed: Chemical and biological analyses of the essential oils and main constituents of Piper species.
PubMed: Down-regulation of survivin and hypoxia-inducible factor-1 α by β-elemene enhances the radiosensitivity of lung adenocarcinoma xenograft.
PubMed: Β-elemene inhibits Hsp90/Raf-1 molecular complex inducing apoptosis of glioblastoma cells.
PubMed: β-Elemene induces apoptosis as well as protective autophagy in human non-small-cell lung cancer A549 cells.
PubMed: Applications of nanoparticles in herbal medicine: zedoary turmeric oil and its active compound β-elemene.
PubMed: [Analysis of content changes of volatile oil and beta-elemene in oil in Sarcandrae].
PubMed: Chemical composition of the essential oil from basil (Ocimum basilicum Linn.) and its in vitro cytotoxicity against HeLa and HEp-2 human cancer cell lines and NIH 3T3 mouse embryonic fibroblasts.
PubMed: Synergistic antitumor effect of β-elemene and etoposide is mediated via induction of cell apoptosis and cell cycle arrest in non-small cell lung carcinoma cells.
PubMed: Fractionation of volatile constituents from curcuma rhizome by preparative gas chromatography.
PubMed: California Lomatiums, Part X. Comparison of composition of the hydrodistilled oils from two subspecies of Lomatium mohavense.
PubMed: Cbl-regulated Akt and ERK signals are involved in β-elemene-induced cell apoptosis in lung cancer cells.
PubMed: Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed: [GC-MS analysis of volatile oil of olibanum].
PubMed: Anti-cancer natural products isolated from chinese medicinal herbs.
PubMed: The compositions of volatiles and aroma-active compounds in dried omija fruits (Schisandra chinensis Baillon) according to the cultivation areas.
PubMed: Downregulation effects of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14 expression in rats with liver fibrosis.
PubMed: [GC-MS analysis of essential oil from root of Angelica dahurica cv. Qibaizhi].
PubMed: P21 (waf1/cip1) is required for non-small cell lung cancer sensitive to Gefitinib treatment.
PubMed: Protection of endothelial cells, inhibition of neointimal hyperplasia by β-elemene in an injured artery.
PubMed: β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis.
PubMed: β-elemene inhibits proliferation of human glioblastoma cells through the activation of glia maturation factor β and induces sensitization to cisplatin.
PubMed: Chemical composition, antimicrobial and antioxidant activities of essential oil from Gnaphlium affine.
PubMed: Volatile constituent distribution of Prangos coryombosa Boiss at two stages of growth.
PubMed: Comparative volatile oil composition of four Ocimum species from northern India.
PubMed: Chemical composition and antibacterial activity of the essential oil of Drimys granadensis L.f. leaves from Colombia.
PubMed: Composition of the essential oil of Bidens tripartita L. roots and its antibacterial and antifungal activities.
PubMed: Essential oil composition of Vismia macrophylla leaves (Guttiferae).
PubMed: [Comparison of content of curdione, curcumol, germacrone and beta-elemene in different varieties of vinegar backed Rhizoma Curcuma].
PubMed: Caryophyllene oxide-rich essential oils of Lithuanian Artemisia campestris ssp. campestris and their toxicity.
PubMed: β-Elemene piperazine derivatives induce apoptosis in human leukemia cells through downregulation of c-FLIP and generation of ROS.
PubMed: Chemical composition and antimicrobial activity of the essential oils of Anthospermum emirnense and Anthospermum perrieri (Rubiaceae).
PubMed: Amelioration of experimental autoimmune encephalomyelitis by β-elemene treatment is associated with Th17 and Treg cell balance.
PubMed: Preparation and characterization of β-elemene-loaded microemulsion.
PubMed: Efficient synthesis of the anticancer β-elemene and other bioactive elemanes from sustainable germacrone.
PubMed: ß-Elemene inhibits proliferation of human glioblastoma cells and causes cell-cycle G0/G1 arrest via mutually compensatory activation of MKK3 and MKK6.
PubMed: GC-MS analysis of headspace and liquid extracts for metabolomic differentiation of citrus Huanglongbing and zinc deficiency in leaves of 'Valencia' sweet orange from commercial groves.
PubMed: Evaluation of cisplatin in combination with β-elemene as a regimen for prostate cancer chemotherapy.
PubMed: Preparation, characterization and relative bioavailability of oral elemene o/w microemulsion.
PubMed: [Mechanism study of beta-elemene derivative (ET) in NB4 cell on apoptosis induction].
PubMed: Antineoplastic effect of beta-elemene on prostate cancer cells and other types of solid tumour cells.
PubMed: Beta-elemene inhibits melanoma growth and metastasis via suppressing vascular endothelial growth factor-mediated angiogenesis.
PubMed: [HPLC determination of six components in zedoary turmeric oil and its related injections].
PubMed: [Effects of beta-elemene on proliferation and apoptosis of human multiple myeloma cell RPMI-8226].
PubMed: Preparative isolation and purification of six volatile compounds from essential oil of Curcuma wenyujin using high-performance centrifugal partition chromatography.
PubMed: Downregulation of IL-17 and IFN-gamma in the optic nerve by beta-elemene in experimental autoimmune encephalomyelitis.
PubMed: Exploiting cyanobacterial P450 pathways.
PubMed: [Analysis on chemical components of volatile oil and determination of thymoquinone from seed of Nigella glandulifera].
PubMed: [beta-elemene enhances aclarubicin-induced apoptotic effect in HL-60 cells and its mechanism.].
PubMed: Essential oils from two Lantana species with antimycobacterial activity.
PubMed: Different isolation methods for determination of composition of volatiles from Nigella damascena L. seeds.
PubMed: Volatile constituents of Ocimum minimum herb cultivated in Portugal.
PubMed: Essential oil composition from two species of Piperaceae family grown in Colombia.
PubMed: Seasonal variation and bioactivity in the leaf oil of Liriodendron tulipifera growing in Huntsville, Alabama.
PubMed: beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis.
PubMed: [Beta-elemene inhibits expression of ANG II and RhoA/ROCK signaling in hepatic stellate cells].
PubMed: ANG II-AT1 receptor pathway is involved in the anti-fibrotic effect of beta-elemene.
PubMed: Essential oil compositions of three Lantana species from Monteverde, Costa Rica.
PubMed: Radioactive synthesis and biodistribution study of beta-elemene-99mTc(CO)3 conjugates.
PubMed: Antiulcerogenic and anti-inflammatory activities of the essential oil from Pterodon emarginatus seeds.
PubMed: Anti-cancer properties of Nigella spp. essential oils and their major constituents, thymoquinone and beta-elemene.
PubMed: Synthesis and in vitro anti-proliferative activity of beta-elemene monosubstituted derivatives in HeLa cells mediated through arrest of cell cycle at the G1 phase.
PubMed: Validation of a sensitive gas chromatographic-mass spectrometric method for the simultaneous determination of beta-elemene and beta-elemenal in human plasma.
PubMed: [Effect of beta-elemene on the proliferation, migration and RhoA expression of hepatic stellate cells induced by angiotensin II].
PubMed: Terpene biosynthesis in glandular trichomes of hop.
PubMed: Morphological, genetic, and chemical polymorphism of Curcuma kwangsiensis.
PubMed: Antibacterial terpenes from the oleo-resin of Commiphora molmol (Engl.).
PubMed: N-(beta-Elemene-13-yl)tryptophan methyl ester induces apoptosis in human leukemia cells and synergizes with arsenic trioxide through a hydrogen peroxide dependent pathway.
PubMed: Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation.
PubMed: [Effect of traditional Chinese medicine on quality of life and survival period in patients with progressive gastric cancer].
PubMed: Ab initio analysis of the Cope rearrangement of germacrane sesquiterpenoids.
PubMed: The influence of different nutrient levels on insect-induced plant volatiles in Bt and conventional oilseed rape plants.
PubMed: Bioactivity and chemical composition of the leaf essential oils of Zanthoxylum rhoifolium and Zanthoxylum setulosum from Monteverde, Costa Rica.
PubMed: Volatile components from the roots of Solanum pseudocapsicum.
PubMed: Interception of the enzymatic conversion of farnesyl diphosphate to 5-epi-aristolochene by using a fluoro substrate analogue: 1-fluorogermacrene A from (2E,6Z)-6-fluorofarnesyl diphosphate.
PubMed: [Extraction and identification of volatile constituents in the flowers of Aglaia odorata Lour].
PubMed: The volatile constituents analysis of Eremostachys macrophylla Montbr. & Auch. from Iran.
PubMed: In vitro combination characterization of the new anticancer plant drug beta-elemene with taxanes against human lung carcinoma.
PubMed: The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes.
PubMed: [GC-MS analysis of essential oil from anthodiums of Chrysanthemum morifolium processed by microwave-airflow and steam calefaction].
PubMed: Immunotherapeutic effects on murine pancreatic carcinoma by β-elemene combined with dendritic cells modified with genes encoding interleukin-23.
PubMed: Essential oil constituents from Japanese and Indian Curcuma aromatica rhizomes.
PubMed: Effect of ginseng saponin, arsenic trioxide, beta-elemene combined with CTX on telomere-telomerase system in K562 cell line.
PubMed: [Research of beta-elemene interventional treatment on VX2 carcinoma transplanted on kidney in rabbits].
PubMed: Simultaneous determination of 11 characteristic components in three species of Curcuma rhizomes using pressurized liquid extraction and high-performance liquid chromatography.
PubMed: [Immunotherapeutic effects of beta-elemene combined with interleukin-23 gene-modified dendritic cells on murine pancreatic carcinoma].
PubMed: Analysis of volatile components of Curcuma sichuanensis X. X. Chen by gas chromatography-mass spectrometry.
PubMed: From terpenoids to aliphatic acids: further evidence for late-instar switch in osmeterial defense as a characteristic trait of swallowtail butterflies in the tribe papilionini.
PubMed: Screening and analysis of bioactive compounds in traditional Chinese medicines using cell extract and gas chromatography-mass spectrometry.
PubMed: Optimization of GC-MS conditions based on resolution and stability of analytes for simultaneous determination of nine sesquiterpenoids in three species of Curcuma rhizomes.
PubMed: [Radiosensitization of beta-elemene on VX2 carcinoma transplanted on kidney in rabbits in vivo].
PubMed: [Analysis of volatile constituents in leaves of three cypress species by gas chromatography/mass spectrometry].
PubMed: [Study on pharmacokinetics of PVP coated beta-elemene liposome in rats].
PubMed: The synthesis and anti-proliferative effects of beta-elemene derivatives with mTOR inhibition activity.
PubMed: Assessing the quality of RCTs on the effect of beta-elemene, one ingredient of a Chinese herb, against malignant tumors.
PubMed: Characterization and body distribution of beta-elemene solid lipid nanoparticles (SLN).
PubMed: Essential oil analysis and anticancer activity of leaf essential oil of Croton flavens L. from Guadeloupe.
PubMed: Headspace solid-phase microextraction-gas chromatography--mass spectrometry analysis of the volatile compounds of Evodia species fruits.
PubMed: The pharmacokinetics of a novel anti-tumor agent, beta-elemene, in Sprague-Dawley rats.
PubMed: [Excretion of beta-elemene from rat respiratory tracts].
PubMed: Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase.
PubMed: Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death.
PubMed: Analysis of leaf surface sesquiterpenes in potato varieties.
PubMed: Application of multidimensional gas chromatography to the enantioselective characterisation of the essential oil of Eupatorium buniifolium Hooker et Arnott.
PubMed: Isogermacrene A, a proposed intermediate in sesquiterpene biosynthesis.
PubMed: Essential oil yield and quality of methyl eugenol rich Ocimum tenuiflorum L.f. (syn. O. sanctum L.) grown in south India as influenced by method of harvest.
PubMed: [Reversal of resistance to adriamycin in human breast cancer cell line MCF-7/ADM by beta-elemene].
PubMed: [Effects of arsenic trioxide, ginseng saponin and beta-elemene on telomere-telomerase system in K562 cell line].
PubMed: Composition and functional properties of the essential oil of amazonian basil, Ocimum micranthum Willd., Labiatae in comparison with commercial essential oils.
PubMed: Volatile constituents and key odorants in leaves, buds, flowers, and fruits of Laurus nobilis L.
PubMed: Sesquiterpenes of the liverwort Scapania undulata.
PubMed: [Quantum chemistry Ab initio calculation of vibration spectrum of beta-elemene].
PubMed: GC-MS analysis of essential oil of Shorea robusta bast.
PubMed: Interspecific variation in terpenoid composition of defensive secretions of European Reticulitermes termites.
PubMed: Differential volatile emissions and salicylic acid levels from tobacco plants in response to different strains of Pseudomonas syringae.
PubMed: Essential oil from fruit of Peucedanum tauricum Bieb.
PubMed: [Constituents analysis on volatile oil of Pogostemon cablin from different collection time cultivated in Hainan].
PubMed: Monitoring and fast detection of mycotoxin-producing fungi based on headspace solid-phase microextraction and headspace sorptive extraction of the volatile metabolites.
PubMed: [Effect of PIC-BE on the expression of MDR-1 and bcl-2 genes in a multidrug resistance cell variant K562/ADM].
PubMed: [Supercritical fluid extraction of beta-elemene under lower pressure].
PubMed: [Determination of elemenyl piperidine salt in water by capillary gas chromatography].
PubMed: Aroma compound analysis of Piper nigrum and Piper guineense essential oils from Cameroon using solid-phase microextraction-gas chromatography, solid-phase microextraction-gas chromatography-mass spectrometry and olfactometry.
PubMed: Volatile sesquiterpene hydrocarbons characteristic for Penicillium roqueforti strains producing PR toxin.
PubMed: Germacrene A is a product of the aristolochene synthase-mediated conversion of farnesylpyrophosphate to aristolochene.
PubMed: Seco-sethukarailin, a novel diterpenoid from the soft coral Sinularia dissecta.
PubMed: Effect of the essential oil from the flowers of Magnolia sieboldii on the lipopolysaccharide-induced production of nitric oxide and prostaglandin E2 by rat peritoneal macrophages.
PubMed: [beta-elemene induces apoptosis of K562 leukemia cells].
PubMed: [Preliminary study on the antitumor immuno-protective mechanism of beta-elemene].
PubMed: Germacrenes from fresh costus roots.
PubMed: Essential oils from Azorean Laurus azorica.
PubMed: A chemotaxonomic investigation of volatile constituents in Stachys subsect. Swainsonianeae (Labiatae).
PubMed: [Pharmacokinetics and disposition of beta-elemene in rats].
PubMed: Biosynthesis of germacrene A carboxylic acid in chicory roots. Demonstration of a cytochrome P450 (+)-germacrene a hydroxylase and NADP+-dependent sesquiterpenoid dehydrogenase(s) involved in sesquiterpene lactone biosynthesis.
PubMed: [Studies on metabolite of beta-elemene in rat bile].
PubMed: Essential oil analysis of Eusteralis deccanensis Panigrahi (Lamiaceae).
PubMed: Chemical variability of the volatile metabolites from the Caribbean corals of the genus Gorgonia.
PubMed: Synthesis of sesquiterpene derivatives as potential antitumor agents; elemane derivatives.
PubMed: Cytotoxic terpenoids from the Formosan soft coral Nephthea brassica.
PubMed: (+)-Germacrene A biosynthesis . The committed step in the biosynthesis of bitter sesquiterpene lactones in chicory
PubMed: Terpenoid composition of the wound-induced bark exudate of Commiphora tenuis from Ethiopia.
PubMed: Chemical and antibacterial studies of two Helichrysum species of Greek origin.
PubMed: Sesquiterpenes in the frontal gland secretions of nasute soldier termites from New Guinea.
PubMed: Recent advances in pharmacologic study of natural anticancer agents in China.
PubMed: Components of moribund American elm trees as attractants to elm bark beetles,Hylurgopinus rufipes andScolytus multistriatus.
PubMed: Constituents of osmeterial secretion of pre-final instar larvae of citrus swallowtail,Papilio demodocus (Esper) (Lepidoptera: Papilionidae).
PubMed: Further studies of the terpenoid content in the gorgonian Eunicea succinea: 12,13-bisepieupalmerin, a new cembranolide.
PubMed: [Antitumor effect and pharmacological actions of beta-elemene isolated from the rhizome of Curcuma aromatica].
PubMed: Larval osmeterial secretions of the swallowtails (Papilio).
PubMed: Chemical composition of the frontal gland secretion ofSyntermes soldiers (Isoptera, Termitidae).
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