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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 90.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 56.00 to 58.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 311.00 to 312.00 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 238.00 °F. TCC ( 114.60 °C. ) (est)
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| logP (o/w): | 4.703 (est) |
| Soluble in: |
| | alcohol | | | water, 2.216 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
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| Odor Type: spicy |
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| | spicy peppery woody |
Odor Description: at 100.00 %. | spicy peppery woody |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
Safety References:
References:
| | 2-[(2R,6S)-6,10-dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 161437 |
| Pubchem (sid): | 135144562 |
| Pherobase: | View |
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| No odor group found for these |
| | salvia atropatana bunge oil iran | |
| amber |
| | amber carane | FR |
| | angelica seed oil CO2 extract | FL/FR |
| | sarcocaulon mossamedense wood resinoid | FR |
| anisic |
| bitter | fennel seed oil spain | FR |
| balsamic |
| | amyris wood oil | FL/FR |
| | copaiba balsam oil | FL/FR |
| | copaiba balsam oil replacer | FR |
| | frankincense absolute | FL/FR |
| | guaiyl acetate | FL/FR |
| | hemlock western oil (tsuga heterophylla) canada | FR |
| | opoponax absolute (balsamodendron kafal) | FL/FR |
| | tolu balsam oil | FL/FR |
| earthy |
| | cabralea cangerana root bark oil | FR |
| 3- | octanol | FL/FR |
| floral |
| alpha- | bisabolol | FL/FR |
| | dihydrojasmone | FL/FR |
| | mimosa absolute france | FL/FR |
| green |
| 2,5- | dimethyl bicyclo(3.2.1)oct-2-ene | FR |
| | octanal diethyl acetal | FL/FR |
| herbal |
| | anthemis nobilis flower oil roman | FL/FR |
| | canarium luzonicum oil | FL/FR |
| curled | parsley seed oil | FL/FR |
| common | tansy flower oil | FR |
| common | tansy flower oil dutch | FR |
| | theaspirane | FL/FR |
| peppery |
| | asarum europaeum oil | FR |
| phenolic |
| 4- | methyl-2,6-dimethoxyphenol | FL/FR |
| spicy |
| | allspice berry absolute | FL/FR |
| | atractylis root oil | FR |
| | carvacrol | FL/FR |
| 4- | carvomenthenol | FL/FR |
| | caryophyllene | FL/FR |
| beta- | caryophyllene | FL/FR |
| alpha- | caryophyllene alcohol | FL/FR |
| | cascarilla oil replacer | FL/FR |
| | cinnamon bark oil ceylon | FL/FR |
| | cinnamon leaf oil ceylon | FL/FR |
| | cinnamon oleoresin ceylon | FL/FR |
| | clove bud absolute | FL/FR |
| | croton eluteria bark oil | FL/FR |
| | ethyl vinyl ketone | FL/FR |
| | galangal root oil | FL/FR |
| | ginger oleoresin africa | FL/FR |
| | ginger root oil brazil | FL/FR |
| | ginger root oil china | FL/FR |
| | grains of paradise oil | FL/FR |
| | mace absolute | FL/FR |
| | mace fragrance | FR |
| | mace oil | FL/FR |
| | methyl heptadienone | FL/FR |
| | myrcene | FR |
| | orthodon dianthera maxim. oil vietnam | |
| black | pepper absolute | FL/FR |
| | pepper hexanone | FR |
| black | pepper oil | FL/FR |
| black | pepper oil replacer | FR |
| black | pepper oleoresin | FL/FR |
| | pepper tree berry oil | FL/FR |
| (E,E)- | piperine | FL/FR |
| | spicy carbonate | FR |
| (E)- | tiglic acid | FL/FR |
| | turmeric root absolute | FL/FR |
| | zvoulimba leaf oil | FR |
| terpenic |
| | angelica seed oil | FL/FR |
| para- | cymene | FL/FR |
| | elemi resinoid | FL/FR |
| | frankincense oil | FL/FR |
| | juniperus communis fruit oil | FL/FR |
| laevo- | limonene | FL/FR |
| | pine needle oil dwarf | FL/FR |
| thujonic |
| common | tansy leaf oil dutch | FR |
| common | tansy oil canada | FR |
| vanilla |
| | vanillin propylene glycol acetal | FL/FR |
| woody |
| iso | caryophyllene | CS |
| | caryophyllene alcohol acetate | FR |
| | caryophyllene formate | FL/FR |
| beta- | caryophyllene oxide | FL/FR |
| atlas | cedarwood oil | FR |
| alpha- | copaene | |
| | dacrydium franklinii wood oil | FR |
| (3S,5R,8S)-3,8- | dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-azulen-1-one | FL/FR |
| | frankincense fragrance | FR |
| | frankincense oil replacer | FR |
| | frankincense resinoid | FL/FR |
| (E)- | germacrene D | FL/FR |
| | guaiacwood oil | FL/FR |
| alpha- | guaiene | FL/FR |
| | juniper berry oleoresin | FL/FR |
| | methyl vetivate | FR |
| gamma- | muurolene | |
| | olibanum specialty | FR |
| | patchouli absolute | FR |
| | rhubarb oxirane | FR |
| | spicy pentanone | FL/FR |
| | spikenard oil | FL/FR |
| | sugi wood oil | FR |
| | xanthoxylum alatum roxb. oil | FR |
| | zedoary bark oil | FL/FR |
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| For Flavor |
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| No flavor group found for these |
| alpha- | bisabolol | FL/FR |
| alpha- | caryophyllene alcohol | FL/FR |
| | caryophyllene formate | FL/FR |
| alpha- | copaene | |
| (3S,5R,8S)-3,8- | dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-azulen-1-one | FL/FR |
| (E)- | germacrene D | FL/FR |
| | grains of paradise oil | FL/FR |
| alpha- | guaiene | FL/FR |
| | guaiyl acetate | FL/FR |
| gamma- | muurolene | |
| | orthodon dianthera maxim. oil vietnam | |
| | salvia atropatana bunge oil iran | |
| | spikenard oil | FL/FR |
| amber |
| | angelica seed oil | FL/FR |
| balsamic |
| | copaiba balsam oil | FL/FR |
| | opoponax absolute (balsamodendron kafal) | FL/FR |
| | tolu balsam oil | FL/FR |
| brown |
| (E)- | tiglic acid | FL/FR |
| cooling |
| 4- | carvomenthenol | FL/FR |
| | theaspirane | FL/FR |
| floral |
| | dihydrojasmone | FL/FR |
| fruity |
| | spicy pentanone | FL/FR |
| green |
| | canarium luzonicum oil | FL/FR |
| | elemi resinoid | FL/FR |
| | methyl heptadienone | FL/FR |
| | octanal diethyl acetal | FL/FR |
| herbal |
| | angelica seed oil CO2 extract | FL/FR |
| | anthemis nobilis flower oil roman | FL/FR |
| curled | parsley seed oil | FL/FR |
| medicinal |
| | frankincense absolute | FL/FR |
| musty |
| 3- | octanol | FL/FR |
| phenolic |
| 4- | methyl-2,6-dimethoxyphenol | FL/FR |
| pine |
| | pine needle oil dwarf | FL/FR |
| solvent |
| | methyl phenyl sulfide | FL |
| spicy |
| | allspice berry absolute | FL/FR |
| | carvacrol | FL/FR |
| beta- | caryophyllene | FL/FR |
| | caryophyllene | FL/FR |
| | cascarilla oil replacer | FL/FR |
| | cinnamon bark oil ceylon | FL/FR |
| | cinnamon leaf oil ceylon | FL/FR |
| | cinnamon oleoresin ceylon | FL/FR |
| | clove bud absolute | FL/FR |
| | croton eluteria bark oil | FL/FR |
| | ethyl vinyl ketone | FL/FR |
| | galangal root oil | FL/FR |
| | ginger oleoresin africa | FL/FR |
| | ginger root oil brazil | FL/FR |
| | ginger root oil china | FL/FR |
| | mace absolute | FL/FR |
| | mace oil | FL/FR |
| black | pepper absolute | FL/FR |
| black | pepper oil | FL/FR |
| black | pepper oleoresin | FL/FR |
| | pepper tree berry oil | FL/FR |
| (E,E)- | piperine | FL/FR |
| | turmeric root absolute | FL/FR |
| terpenic |
| para- | cymene | FL/FR |
| | juniperus communis fruit oil | FL/FR |
| laevo- | limonene | FL/FR |
| vanilla |
| | vanillin propylene glycol acetal | FL/FR |
| waxy |
| | mimosa absolute france | FL/FR |
| woody |
| | amyris wood oil | FL/FR |
| beta- | caryophyllene oxide | FL/FR |
| | frankincense oil | FL/FR |
| | frankincense resinoid | FL/FR |
| | guaiacwood oil | FL/FR |
| | juniper berry oleoresin | FL/FR |
| | zedoary bark oil | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2-[(2R,10S)-6,10- | dimethyl spiro[4.5]dec-6-en-2-yl]-2-propanol | | 2-[(2R,10S)-6,10- | dimethylspiro[4.5]dec-6-en-2-yl]-2-propanol | | 2-[(2R,6S)-6,10- | dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol | | | hinesol | | epi- | hinesol | | | spiro(4.5)dec-6-ene-2-methanol, a,a,6,10-tetramethyl-, (2R-(2a,5a(S*)))- | | (2R-(2alpha,5alpha(S*)))- alpha,alpha,6,10- | tetramethyl spiro(4.5)dec-6-ene-2-methanol |
Articles:
| PubMed: | [Studies on terpenoids from Zygophyllum fabago]. |
| PubMed: | Sulphur-containing compounds in the essential oil of Ferula alliacea roots and their mass spectral fragmentation patterns. |
| PubMed: | [Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea]. |
| PubMed: | Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells. |
| PubMed: | Traditional herbal medicine for the control of tropical diseases. |
| PubMed: | [Study on the chemical components of volatile oil from Euphorbia pekinensis radix]. |
| PubMed: | Molecular docking and ADME studies of natural compounds of Agarwood oil for topical anti-inflammatory activity. |
| PubMed: | Composition and evaluation of the anti-inflammatory and anticancer activities of the essential oil from Annona sylvatica A. St.-Hil. |
| PubMed: | Chemical composition and in vitro antimicrobial activity of the essential oil of Cyclotrichium leucotrichum from Iran. |
| PubMed: | In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. |
| PubMed: | Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis. |
| PubMed: | Chemical composition of volatile oils of Aquilaria malaccensis (Thymelaeaceae) from Malaysia. |
| PubMed: | [Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis]. |
| PubMed: | [Advances in chemistry, molecular biology and pharmacological of Cangzhu]. |
| PubMed: | Identification of volatile compounds of Atractylode lancea rhizoma using supercritical fluid extraction and GC-MS. |
| PubMed: | [Fingerprint of volatile oil of Atractylodes lancea by GC-MS]. |
| PubMed: | [GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood]. |
| PubMed: | [Studies on chemical constituents in essential oil from wild Atractylodes lancea in dabie mountains]. |
| PubMed: | A phosphine-catalyzed [3+2] cycloaddition strategy leading to the first total synthesis of (-)-hinesol. |
| PubMed: | [The naphtha composing characteristics of geoherbs of Atractylodes lancea]. |
| PubMed: | [GC-MS analysis of essential oils from rhizomes of Atractylodes lancea (Thunb.) DC. and A. chinensis (DC.) Koidz]. |
| PubMed: | Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying. |
| PubMed: | Effects of sesquiterpenoids from "Oriental incenses" on acetic acid-induced writhing and D2 and 5-HT2A receptors in rat brain. |
| PubMed: | Inhibition of H+,K+ -ATPase by hinesol, a major component of So-jutsu, by interaction with enzyme in the E1 state. |
| PubMed: | Biotransformation of hinesol isolated from the crude drug Atractylodes lancea by Aspergillus niger and Aspergillus cellulosae. |
| PubMed: | Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures. |
| PubMed: | Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants. |
| PubMed: | A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis. |
| PubMed: | [Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes]. |
| PubMed: | Effect of jinkoh-eremol and agarospirol from agarwood on the central nervous system in mice. |
| PubMed: | Botanical and chemical evaluation of Atractylodes lancea plants propagated in vitro and by division of the rhizome. |
| PubMed: | Intestinal motility enhancing effect of Atractylodes lancea rhizome. |
| PubMed: | Antihepatotoxic principles of Atractylodes rhizomes. |
| PubMed: | Stereochemical relationships in spirovetivane sesquiterpenes: the total synthesis of hinesol. |
| PubMed: | Studies on the constituents of atractylodes. X. Correlation of hinesol and beta-vetivone. |
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