tolualdehydes (mixed o,m,p)
tolualdehyde isomers
 
Notes:
Used as a food additive [EAFUS]
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-504-6093
      Fax: 1-631-614-7828
      US Voice: 1-631-504-6093
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
      Facebook
      Twitter
      Linkedin
      Blog
      Get the App!
      Product(s):
      1334-78-7 Benzaldehyde, methyl-
       
  • CSA
Synonyms   Articles   Notes   Search
    Flavor Demo Formulas
CAS Number: 1334-78-7Picture of molecule3D/inchi
Other: 8027-79-0
ECHA EINECS - REACH Pre-Reg: 215-615-1
FDA UNII: ALC105UA3K
CoE Number: 115
Molecular Weight: 120.15096000
Formula: C8 H8 O
NMR Predictor: Predict (works with chrome or firefox)
Also(can) Contains: ortho-tolualdehyde
 meta-tolualdehyde
 para-tolualdehyde
EFSA/JECFA Comments: At least 95% (sum of o,m,p-isomers) (EFSA) CASrn does not specify position of methyl substituent, "Incompletely Defined Substance". Composition of mixture to be specified.
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 866  tolualdehydes (mixed o,m,p)
DG SANTE Food Flavourings: 05.027  tolualdehydes (mixed o,m,p)
FEMA Number: 3068 tolualdehydes (mixed o,m,p)
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):1334-78-7 ; TOLUALDEHYDES (MIXED O-, M-, P-)
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.515 Synthetic flavoring substances and adjuvants.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: colorless clear liquid (est)
Assay: 95.00 to 100.00 % sum of isomers
Additional Assay Information: sum of o,m,p isomers
Food Chemicals Codex Listed: No
Specific Gravity: 1.01900 to 1.02900 @  25.00 °C.
Pounds per Gallon - (est).: 8.479 to  8.562
Refractive Index: 1.54000 @  20.00 °C.
Boiling Point: 198.00 to  201.00 °C. @ 760.00 mm Hg
Acid Value: 5.00 max. KOH/g
Vapor Pressure: 0.335000 mmHg @ 25.00 °C. (est)
Flash Point: 176.00 °F. TCC ( 80.00 °C. )
logP (o/w): 2.260 (est)
Soluble in:
 alcohol
 water, 1183 mg/L @ 25 °C (est)
Insoluble in:
 water
Similar Items: note
meta-tolualdehyde
ortho-tolualdehyde
para-tolualdehyde
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: fruity
 
Odor Strength: high ,
recommend smelling in a 1.00 % solution or less
 
 sweet  cherry  chemical  coumarinic  powdery  
Odor Description:
at 1.00 % in dipropylene glycol. 
sweet cherry chemical coumarin powdery
 
 sweet  cherry  chemical  powdery  coumarinic  
Odor Description:
Sweet, cherry and chemical with a powdery coumarin like nuance
Mosciano, Gerard P&F 16, No. 1, 31, (1991)
 
 
Flavor Type: fruity
 
 cherry  coumarinic  almond  sweet  powdery  hay  vanilla  
Taste Description:
at 15.00 ppm.  
Cherry pit, coumarin, almond, sweet, with a slight powdery hay and vanilla like nuance
Mosciano, Gerard P&F 16, No. 1, 31, (1991)
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
BOC Sciences
For experimental / research use only.
Benzaldehyde, methyl-
Citrus and Allied Essences
Tolualdehydes (mixed o,m,p)
Market Report
Tengzhou Xiang Yuan Aroma Chemicals
Tolualdehydes
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the CSA
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Human Experience:
4 % solution: no irritation or sensitization.
Oral/Parenteral Toxicity:
oral-rat LD50  2250 mg/kg
(Moreno, 1973w)

oral-rat LD50  2250 mg/kg
Food and Cosmetics Toxicology. Vol. 14, Pg. 885, 1976.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect: Dermal sensitization
IFRA: View Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.085 %
Category 2: Products applied to the axillae
0.025 %
Category 3: Products applied to the face/body using fingertips
0.51 %
Category 4: Products related to fine fragrance
0.47 %
 Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.12 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.12 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.12 %
Category 5D: Baby Creams, baby Oils and baby talc
0.12 %
Category 6: Products with oral and lip exposure
0.28 %
 Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.96 %
Category 7B: Leave-on products applied to the hair with some hand contact
0.96 %
Category 8: Products with significant anogenital exposure
0.050 %
Category 9: Products with body and hand exposure, primarily rinse off
0.92 %
 Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
3.30 %
Category 10B: Household aerosol/spray products
3.30 %
 Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
1.80 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
1.80 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
No Restriction
 Notes:
IFRA FLAVOR REQUIREMENTS:

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.

 
Maximised Survey-derived Daily Intakes (MSDI-EU): 230.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 1100.00 (μg/capita/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -28.00000
beverages(nonalcoholic): -11.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -430.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -16.00000
fruit ices: -16.00000
gelatins / puddings: -8.30000
granulated sugar: --
gravies: --
hard candy: -25.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: -100.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of benzyl derivatives used as flavor ingredients. View pdf
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 20 (FGE.20): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical group 23
View page or View pdf
Flavouring Group Evaluation 52 (FGE.52): Consideration of hydroxy- and alkoxy-substituted benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters evaluated by EFSA in FGE.20 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 54 (FGE.54)[1] - Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20 (2005) - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food
View page or View pdf
Flavouring Group Evaluation 20, Revision 1 (FGE.20Rev1): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters from chemical group 23
View page or View pdf
Flavouring Group Evaluation 54, Revision 1 (FGE.54Rev1): Consideration of benzyl derivatives evaluated by JECFA (57th meeting) structurally related to benzyl alcohols, benzaldehydes, a related acetal, benzoic acids and related esters evaluated by EFSA in FGE.20Rev1 (2009)
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 2 (FGE.20Rev2): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30
View page or View pdf
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 1334-78-7
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0001334787
Synonyms   Articles   Notes   Search   Top
References:
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 1334-78-7
Pubchem (sid): 134979317
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): HMDB29638
FooDB: FDB010397
VCF-Online: VCF Volatile Compounds in Food
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
anisic
para-acetanisoleFL/FR
balsamic
 benzyl cinnamateFL/FR
 methyl (E)-cinnamateFL/FR
 methyl cinnamateFL/FR
berry
 raspberry ketone methyl etherFL/FR
camphoreous
 butyrophenoneFL/FR
coconut
alpha-angelica lactoneFL/FR
coumarinic
 phthalideFL/FR
 tonka furanoneFL/FR
creamy
para-vanillic acidFL/FR
ethereal
 cyclohexyl formateFL/FR
floral
para-anisyl nitrileFR
 hawthorn fragranceFR
 hawthorn specialtyFR
 linden flower absoluteFR
 linden flower absolute replacerFR
 rhodinyl phenyl acetateFL/FR
fruity
 allyl 2-ethyl butyrateFL/FR
 allyl benzoateFR
 allyl isovalerateFL/FR
bitter almond oilFL/FR
isoamyl 2-methyl butyrateFL/FR
 amyl butyrateFL/FR
para-anisyl propionateFL/FR
 benzaldehydeFL/FR
 benzaldehyde / methyl anthranilate schiff's baseFR
 benzaldehyde glycrol acetalFL/FR
 bread thiopheneFL/FR
 cherry oxyacetateFL/FR
 cherry pentenoateFL/FR
 cherry propanolFL/FR
 cyclohexyl cinnamateFL/FR
 ethyl benzoyl acetateFL/FR
 ethyl methyl-para-tolyl glycidateFL/FR
 heptyl isobutyrateFL/FR
3-methyl-2-butenalFL/FR
meta-tolualdehydeFL/FR
para-tolualdehydeFL/FR
grain
 rice bran absoluteFL/FR
herbal
laevo-perillaldehydeFL/FR
musk
 ethylene brassylateFL/FR
naphthyl
2,4-dimethyl benzaldehydeFL/FR
nutty
2-acetyl-5-methyl furanFL/FR
 nutty cyclohexenoneFL/FR
phenolic
2'-hydroxyacetophenoneFL/FR
powdery
para-anisyl acetateFL/FR
spicy
 cinnamyl isovalerateFL/FR
para-methoxycinnamaldehydeFL/FR
(E)-para-methoxycinnamaldehydeFL/FR
 saffron oil CO2 extractFL/FR
vanilla
 heliotropyl alcoholFL/FR
 vanillyl acetateFL/FR
 vanillylidene acetoneFL/FR
 
For Flavor
 
No flavor group found for these
para-anisyl propionateFL/FR
 butyrophenoneFL/FR
 ethyl 2-phenyl-3-furoateFL
 heliotropyl alcoholFL/FR
(E)-para-methoxycinnamaldehydeFL/FR
 methyl (E)-cinnamateFL/FR
 methyl furfuracrylateFL
 tonka furanoneFL/FR
anisic
para-acetanisoleFL/FR
aromatic
laevo-perillaldehydeFL/FR
balsamic
 vanillylidene acetoneFL/FR
berry
 heptyl isobutyrateFL/FR
 raspberry ketone methyl etherFL/FR
cherry
para-methoxycinnamaldehydeFL/FR
coumarinic
 phthalideFL/FR
creamy
alpha-angelica lactoneFL/FR
para-vanillic acidFL/FR
ethereal
 allyl 2-ethyl butyrateFL/FR
 allyl isovalerateFL/FR
bitter almond oilFL/FR
isoamyl 2-methyl butyrateFL/FR
 amyl butyrateFL/FR
para-anisyl acetateFL/FR
 benzaldehydeFL/FR
 benzaldehyde glycrol acetalFL/FR
 bread thiopheneFL/FR
 cherry oxyacetateFL/FR
 cherry pentenoateFL/FR
 cherry propanolFL/FR
 cinnamyl isovalerateFL/FR
 cyclohexyl cinnamateFL/FR
 ethyl benzoyl acetateFL/FR
 ethyl methyl-para-tolyl glycidateFL/FR
3-methyl-2-butenalFL/FR
meta-tolualdehydeFL/FR
grain
 rice bran absoluteFL/FR
green
 cyclohexyl formateFL/FR
musk
 ethylene brassylateFL/FR
naphthyl
2,4-dimethyl benzaldehydeFL/FR
2'-hydroxyacetophenoneFL/FR
nutty
2-acetyl-5-methyl furanFL/FR
 nutty cyclohexenoneFL/FR
powdery
 powdery ketoneFL
spicy
 benzyl cinnamateFL/FR
 methyl cinnamateFL/FR
 saffron oil CO2 extractFL/FR
para-tolualdehydeFL/FR
vanilla
 vanillyl acetateFL/FR
waxy
 rhodinyl phenyl acetateFL/FR
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 almondFR
 cherry black cherryFR
 cherry maraschino cherryFL
 chocolateFR
 heliotropeFR
 powderFR
 vanillaFR
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 beef
Search  PMC Picture
 cider
Search  PMC Picture
 coffee
Search  PMC Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
 cresyl aldehyde (mixed 2,3,4)
 methyl benzaldehyde (mixed 2,3,4)
 tolualdehyde isomers
 tolualdehydes
 toluene carboxaldehyde (mixed 2,3,4)
 toluic aldehyde (mixed 2,3,4)
 tolyl aldehyde (mixed 2,3,4)
Synonyms   Articles   Notes   Search   Top
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2020 Perflavory ™ Disclaimer Privacy Policy