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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | yellow viscous liquid (est) |
| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | alcohol | | | water, 301.1 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
Cosmetic Information:
Suppliers:
| Hermitage Oils |
| Japanese Hibawood Essential Oil
Odor: characteristic Use: Adam Michael this to say “The aroma of hibawood oil has a young Virginian cedarwood aura about it, dry sweet, very dusty, pencil shaving nuances throughout and for me alone I detect a gloopy fleeting chocolate character comparable to what I find when smelling Amyris balsamifera. |
Safety Information:
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 817, 1979.
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| Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 817, 1979.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for thujopsis dolabrata wood oil usage levels up to: | | | 7.0000 % in the fragrance concentrate.
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| Recommendation for thujopsis dolabrata wood oil flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
| |
| For Odor |
| amber |
| | amber acetate | FR |
| | amber cyclohexanol | FR |
| | amber decane | FR |
| | amber spirolene | FR |
| | ambergris tincture | FL/FR |
| | ambermax 50 (Givaudan) | FR |
| | ambrette seed absolute | FL/FR |
| | ambroxan | FL/FR |
| | formoxymethyl isolongifolene | FR |
| balsamic |
| 1- | benzoyl acetone | FL/FR |
| | bornyl acetate | FL/FR |
| iso | bornyl formate | FL/FR |
| | cedar forest fragrance | FR |
| | copaiba balsam oil | FL/FR |
| dextro- | fenchone | FL/FR |
| | fir needle oil siberia | FL/FR |
| | hemlock western oil (tsuga heterophylla) canada | FR |
| bitter |
| | gentian absolute | FL/FR |
| citrus |
| (E+Z)-4,8- | dimethyl-3,7-nonadien-2-yl acetate | FL/FR |
| | grapefruit oil terpeneless | FL/FR |
| bitter | orange peel oil | FL/FR |
| earthy |
| (-)-alpha- | fenchol | FL/FR |
| red | ginger rhizome oil | FR |
| floral |
| | dihydro-alpha-ionone | FL/FR |
| | floral undecenone | FR |
| | gardenia amide | FR |
| iso | jasmone | FL/FR |
| | linalool oxide | FL/FR |
| | primrose fragrance | FR |
| | verdyl acetate | FR |
| fruity |
| 1-(3,3- | dimethyl bicyclo(2.2.1)hept-2-yl)-2-methyl cyclohex-3-ene carbaldehyde | FR |
| beta- | ionyl ethyl ether | FR |
| | valeriana officinalis root extract | FL/FR |
| green |
| iso | amyl formate | FL/FR |
| iso | cyclocitral (IFF) | FL/FR |
| | galbanum oil | FL/FR |
| | methyl cyclocitrone (IFF) | FR |
| | murraya koenigii leaf oil india | FL/FR |
| | oakmoss oil | FR |
| 2- | propenyl-para-cymene | FR |
| | seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| herbal |
| | clary specialty | FR |
| | herbal carene | FR |
| | herbal undecanol | FR |
| | herbal undecanone | FR |
| 6- | hydroxydihydrotheaspirane (mixture of isomers) | FL/FR |
| | lavandin water absolute | FL/FR |
| (1S,5R)- | myrtenyl acetate | FL/FR |
| laevo-beta- | pinene | FL/FR |
| beta- | pinene | FL/FR |
| alpha- | pinene | FL/FR |
| | tricyclo(5.2.1.02,6)dec-3-enyl acetate | FR |
| mossy |
| | oakmoss absolute | FL/FR |
| | treemoss absolute | FR |
| | treemoss absolute replacer | FR |
| | veramoss (IFF) | FR |
| musk |
| | dehydro beta-linalool | FL/FR |
| | musk dimethyl indane | FL/FR |
| powdery |
| | midnight passion fragrance | FR |
| rooty |
| | vetiveryl propionate | FR |
| spicy |
| | anona squamosa leaf oil | FR |
| 4- | carvomenthenol | FL/FR |
| beta- | caryophyllene | FL/FR |
| | machilus kusanoi leaf oil | FR |
| terpenic |
| | cypress leaf oil | FR |
| thujonic |
| | armoise oil | FR |
| | cedarleaf oil terpeneless | FR |
| | cedarleaf oil western red | FR |
| | sage oil dalmatian | FL/FR |
| common | tansy flower oil argentina | FL/FR |
| common | tansy leaf oil dutch | FR |
| alpha- | thujone | FR |
| beta- | thujone | FR |
| | woody ketone | FL/FR |
| woody |
| | amber decatriene | FR |
| | ambrene acetal | FR |
| | amyris acetate | FR |
| | bark fragrance | FR |
| | caryophyllene alcohol acetate | FR |
| beta- | caryophyllene alcohol acetate | FL/FR |
| beta- | caryophyllene oxide | FL/FR |
| | cedanol | FR |
| | cedar cyclododecatriene | FR |
| | cedar fragrance | FR |
| | cedar specialty | FR |
| atlas | cedarwood absolute | FR |
| | cedarwood acetate | FR |
| atlas | cedarwood oil | FR |
| epoxidized | cedarwood oil | FR |
| | cedarwood oil alcohols | FL/FR |
| | cedarwood oil atlanta | FR |
| | cedarwood oil china | FR |
| | cedarwood oil himalaya | FR |
| | cedarwood oil lebanon | FR |
| | cedarwood oil replacer | FR |
| | cedarwood oil terpenes | FL/FR |
| | cedarwood oil texas | FR |
| | cedarwood oil virginia | FR |
| | cedarwood oil white | FR |
| (R)- | cedralone | FR |
| | cedrela wood oil | FR |
| | cedrelopsis grevei bark oil | FR |
| alpha- | cedrene | FL/FR |
| | cedrene | FR |
| | cedrenol | FL/FR |
| | cedrenyl acetate | FR |
| | cedrol | FL/FR |
| | cedrol methyl ether | FR |
| | cedryl acetate | FL/FR |
| | cedryl methyl ether | FR |
| | cycloionone | FL/FR |
| | cyperus root oil (cyperus scariosus) | FR |
| | dacrydium franklinii wood oil | FR |
| 2- | decalinyl formate | FR |
| | dihydro-beta-ionone | FL/FR |
| 4-(3,3- | dimethyl bicyclo(2.2.1)hept-2-yl)-2-oxabicyclo(2.2.2)octane | FR |
| | dogwood fragrance | FR |
| | dogwood specialty | FR |
| alpha- | ethyl-2,2,6-trimethyl cyclohexane propanol | FR |
| | germacrene B | |
| | guaiene | FL/FR |
| | herbal norbornane | FR |
| | hinoki root oil | FR |
| | juniperus deppeana wood oil | FR |
| | juniperus mexicana extract | FR |
| | labdanum concrete | FR |
| | labdanum ethanone | FR |
| | laminaria absolute | FR |
| iso | longifolene ketone | FR |
| | louro brasileiro wood oil | FR |
| para- | menth-3-en-1-ol | FL/FR |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| | methyl cedryl ketone | FL/FR |
| | methyl cedryl ketone replacer | FR |
| | methyl vetivate | FR |
| | orris hexanone | FR |
| | patchouli ethanone | FR |
| | patchouli fractions | FR |
| | pinacol | FR |
| iso | pinocamphone | FL/FR |
| | sandal pentanol | FR |
| | sandalwood oil west australia (santalum spicatum) | FR |
| | sclareolide | FL/FR |
| | sugi wood oil | FR |
| beta- | terpineol | FL/FR |
| | thuja occidentalis leaf oil | FL/FR |
| | vetiver oil haiti | FL/FR |
| | violet propanol | FR |
| | woody acetate | FR |
| | woody dodecane | FR |
| | woody epoxide | FR |
| | woody ether | FR |
| | woody propanol | FR |
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| For Flavor |
| |
| No flavor group found for these |
| | ambergris tincture | FL/FR |
| 1- | benzoyl acetone | FL/FR |
| beta- | caryophyllene alcohol acetate | FL/FR |
| | cedarwood oil alcohols | FL/FR |
| alpha- | cedrene | FL/FR |
| | dehydro beta-linalool | FL/FR |
| (E+Z)-4,8- | dimethyl-3,7-nonadien-2-yl acetate | FL/FR |
| | gentian absolute | FL/FR |
| | germacrene B | |
| para- | menth-3-en-1-ol | FL/FR |
| laevo-beta- | pinene | FL/FR |
| iso | pinocamphone | FL/FR |
| | seaweed absolute (fucus vesiculosus et serratus) | FL/FR |
| beta- | terpineol | FL/FR |
| | woody ketone | FL/FR |
| balsamic |
| | copaiba balsam oil | FL/FR |
| | fir needle oil siberia | FL/FR |
| berry |
| | dihydro-alpha-ionone | FL/FR |
| camphoreous |
| | bornyl acetate | FL/FR |
| (-)-alpha- | fenchol | FL/FR |
| 6- | hydroxydihydrotheaspirane (mixture of isomers) | FL/FR |
| citrus |
| | grapefruit oil terpeneless | FL/FR |
| bitter | orange peel oil | FL/FR |
| cooling |
| 4- | carvomenthenol | FL/FR |
| dextro- | fenchone | FL/FR |
| | valeriana officinalis root extract | FL/FR |
| green |
| iso | amyl formate | FL/FR |
| iso | cyclocitral (IFF) | FL/FR |
| | galbanum oil | FL/FR |
| iso | jasmone | FL/FR |
| | linalool oxide | FL/FR |
| | oakmoss absolute | FL/FR |
| | lavandin water absolute | FL/FR |
| musk |
| | musk dimethyl indane | FL/FR |
| pine |
| beta- | pinene | FL/FR |
| smoky |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| spicy |
| beta- | caryophyllene | FL/FR |
| | murraya koenigii leaf oil india | FL/FR |
| | turmeric oleoresin | FL |
| thujonic |
| | sage oil dalmatian | FL/FR |
| common | tansy flower oil argentina | FL/FR |
| woody |
| | ambrette seed absolute | FL/FR |
| | ambroxan | FL/FR |
| iso | bornyl formate | FL/FR |
| beta- | caryophyllene oxide | FL/FR |
| | cedarwood oil terpenes | FL/FR |
| | cedrenol | FL/FR |
| | cedrol | FL/FR |
| | cedryl acetate | FL/FR |
| | cycloionone | FL/FR |
| | dihydro-beta-ionone | FL/FR |
| | guaiene | FL/FR |
| | methyl cedryl ketone | FL/FR |
| (1S,5R)- | myrtenyl acetate | FL/FR |
| alpha- | pinene | FL/FR |
| | sclareolide | FL/FR |
| | thuja occidentalis leaf oil | FL/FR |
| | vetiver oil haiti | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | essential oil obtained from the wood of the thujopsis dolabrata, cupressaceae | | | hiba wood oil | | | hibawood oil |
Articles:
| PubMed: | Reduction of the chronic stress response by inhalation of hiba (Thujopsis dolabrata) essential oil in rats. |
| PubMed: | Toxicity of hiba oil constituents and spray formulations to American house dust mites and copra mites. |
| PubMed: | Mast cell stabilizing effect of (-)-Elema-1,3,11(13)-trien-12-ol and thujopsene from Thujopsis dolabrata is mediated by down-regulation of interleukin-4 secretion in antigen-induced RBL-2H3 cells. |
| PubMed: | In vitro and in vivo anti-plasmodial activity of essential oils, including hinokitiol. |
| PubMed: | Isolation and characterization of microsatellite markers for Thujopsis dolabrata var. hondai (Cupressaceae). |
| PubMed: | Antifungal properties of Japanese cedar essential oil from waste wood chips made from used sake barrels. |
| PubMed: | Effects of a combination of hinokitiol (β-thujaplicin) and an organic acid mixture on ruminal fermentation in heifers fed a high-grain diet. |
| PubMed: | In vitro Na+/K+-ATPase inhibitory activity and antimicrobial activity of sesquiterpenes isolated from Thujopsis dolabrata. |
| PubMed: | Isolation of (-)-4'-demethyl traxillagenin from Thujopsis dolabrata Sieb. et Zucc. var. hondai Makino. |
| PubMed: | The antifungal compound totarol of Thujopsis dolabrata var. hondai seeds selects for fungi on seedling root surfaces. |
| PubMed: | The mechanism of the bactericidal activity of hinokitiol. |
| PubMed: | The excellence of Aomori Hiba (Hinokiasunaro) in its use as building materials of Buddhist temples and Shinto shrines. |
| PubMed: | Biological activity of beta-dolabrin, gamma-thujaplicin, and 4-acetyltropolone, hinokitiol-related compounds. |
| PubMed: | Biological activity of alpha-thujaplicin, the isomer of hinokitiol. |
| PubMed: | Biological activity of tropolone. |
| PubMed: | Characterization of (-)-matairesinol as a potent inhibitor of casein kinase I in vitro. |
| PubMed: | Differential effects of the hiba odor on CNV and MMN. |
| PubMed: | Biological activity of 4-acetyltropolone, the minor component of Thujopsis dolabrata SIeb. et Zucc. hondai Mak. |
| PubMed: | Chemotaxonomy on the leaf constituents of Thujopsis dolabrata Sieb. et Zucc.-Analysis of neutral extracts (diterpene hydrocarbon). |
| PubMed: | Biological activity of alpha-thujaplicin, the minor component of Thujopsis dolabrata SIEB. et ZUCC. var. hondai MAKINO. |
| PubMed: | Cytotoxicity of the hinokitiol-related compounds, gamma-thujaplicin and beta-dolabrin. |
| PubMed: | Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities. |
| PubMed: | Phytogrowth-Inhibitory activities of beta-dolabrin and gamma-thujaplicin, hinokitiol-related compounds and constituents of Thujopsis dolabrata Sieb. et Zucc. var hondai Makino. |
| PubMed: | Antimicrobial activity and metalloprotease inhibition of hinokitiol-related compounds, the constituents of Thujopsis dolabrata S. and Z. hondai MAK. |
| PubMed: | Survival strategy of hiba (Thujopsis dolabrata var. hondae) and two broad-leaved trees in northern Japan in response to creep and glide pressures of snow. |
| PubMed: | Induction of hepatic P450s in rat by essential wood and leaf oils. |
| PubMed: | Liver-protective principle of Thujopsis dolabrata leaves. |
| PubMed: | Cytotoxic agents of Thujopsis dolabrata (L. fil.) Sieb. et Zucc. |
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