amarogentin, 21018-84-8

Articles:

PubMed:	Amelioration of oxidative and inflammatory changes by Swertia chirayita leaves in experimental arthritis.
PubMed:	Amarogentin secoiridoid inhibits in vivo cancer cell growth in xenograft mice model and induces apoptosis in human gastric cancer cells (SNU-16) through G2/M cell cycle arrest and PI3K/Akt signalling pathway.
PubMed:	Amarogentin ameliorates diabetic disorders in animal models.
PubMed:	Amarogentin Induces Apoptosis of Liver Cancer Cells via Upregulation of p53 and Downregulation of Human Telomerase Reverse Transcriptase in Mice.
PubMed:	[Chemical constituents of Swertia patens].
PubMed:	Chemotaxonomic Studies of Nine Gentianaceae Species from Western China Based on Liquid Chromatography Tandem Mass Spectrometry and Fourier Transform Infrared Spectroscopy.
PubMed:	Chromatographic Evaluation and Characterization of Components of Gentian Root Extract Used as Food Additives.
PubMed:	Phytochemical investigation of crude methanol extracts of different species of Swertia from Nepal.
PubMed:	Amarogentin Displays Immunomodulatory Effects in Human Mast Cells and Keratinocytes.
PubMed:	Receptor Polymorphism and Genomic Structure Interact to Shape Bitter Taste Perception.
PubMed:	Chinese medicine amygdalin and β-glucosidase combined with antibody enzymatic prodrug system as a feasible antitumor therapy.
PubMed:	Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model.
PubMed:	Contents of therapeutic metabolites in Swertia chirayita correlate with the expression profiles of multiple genes in corresponding biosynthesis pathways.
PubMed:	LC-ESI/MS determination of xanthone and secoiridoid glycosides from in vitro regenerated and in vivo Swertia chirayita.
PubMed:	Detection of intermediates through high-resolution mass spectrometry for constructing biosynthetic pathways for major chemical constituents in a medicinally important herb, Swertia chirayita.
PubMed:	Expression and functional activity of the bitter taste receptors TAS2R1 and TAS2R38 in human keratinocytes.
PubMed:	Comparative HPLC/ESI-MS and HPLC/DAD study of different populations of cultivated, wild and commercial Gentiana lutea L.
PubMed:	Amarogentin, a secoiridoid glycoside, abrogates platelet activation through PLC γ 2-PKC and MAPK pathways.
PubMed:	The bitter barricading of prostaglandin biosynthesis pathway: understanding the molecular mechanism of selective cyclooxygenase-2 inhibition by amarogentin, a secoiridoid glycoside from Swertia chirayita.
PubMed:	Anti-diabetic activity of Swertia corymbosa (Griseb.) Wight ex C.B. Clarke aerial parts extract in streptozotocin induced diabetic rats.
PubMed:	Inhibition of vascular smooth muscle cell proliferation by Gentiana lutea root extracts.
PubMed:	Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis.
PubMed:	Inhibition of aldose reductase by Gentiana lutea extracts.
PubMed:	Phenolic-linked biochemical rationale for the anti-diabetic properties of Swertia chirayita (Roxb. ex Flem.) Karst.
PubMed:	Inhibition of myeloperoxidase and antioxidative activity of Gentiana lutea extracts.
PubMed:	Activity-guided isolation of antioxidant xanthones from Swertia chirayita (Roxb.) H. Karsten (Gentianaceae).
PubMed:	The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin.
PubMed:	Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham.
PubMed:	Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits.
PubMed:	Determination of gentisin, isogentisin, and amarogentin in Gentiana lutea L. by capillary electrophoresis.
PubMed:	Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation.
PubMed:	Quantitative analysis of iridoids, secoiridoids, xanthones and xanthone glycosides in Gentiana lutea L. roots by RP-HPLC and LC-MS.
PubMed:	Liquid chromatography/tandem mass spectrometric study and analysis of xanthone and secoiridoid glycoside composition of Swertia chirata, a potent antidiabetic.
PubMed:	Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model.
PubMed:	Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae).
PubMed:	A sensitive and selective LC-MS-MS method for simultaneous determination of picroside-I and kutkoside (active principles of herbal preparation picroliv) using solid phase extraction in rabbit plasma: application to pharmacokinetic study.
PubMed:	Evaluation of the anticarcinogenic activity of Swertia chirata Buch.Ham, an Indian medicinal plant, on DMBA-induced mouse skin carcinogenesis model.
PubMed:	Production of amarogentin in root cultures of Swertia chirata.
PubMed:	Synthesis of 3,3',5-trihydroxybiphenyl-2-carboxylic acid, a component of the bitterest natural product amarogentin and its coenzyme A and N-acetyl cysteamine thiol esters.
PubMed:	Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms.
PubMed:	Secoiridoids and xanthones from Gentianella nitida.
PubMed:	Secoiridoid glucosides from Swertia mileensis.
PubMed:	Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani.
PubMed:	[Simultaneous determination of five bitter secoiridoid glycosides in nine Chinese Gentiana species used as the Chinese drug "long dan" by high performance liquid chromatography].
PubMed:	Desorption/Chemical ionization mass spectrometry of bitter glycosides from gentiana1.
PubMed:	[High-performance liquid-liquid chromatography in beverage analysis].