Articles:
2-propionylpyrrole
Notes:
Used as a food additive [EAFUS]
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 1073-26-3 2-Propionylpyrrole
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Endeavour Specialty Chemicals Ltd Expertise in high impact aroma chemicals Endeavour Speciality Chemicals offers high-impact aroma chemicals, at small to medium scale. Speciality Chemical has more than 25 years experience of manufacturing high-impact aroma chemicals. With our core expertise in sulfur and heterocyclic chemistries, Endeavours products have applications in a range of industry sectors including flavours and fragrances, pharmaceutical research and material sciences. Endeavour also offer custom synthesis and contract manufacturing services at their UK manufacturing site. Email: Info Email: Sales Voice: +44 (0)1327 310 079 Fax: +44 (0)1327 310 701 Twitter Linkedin News Speciality Chemical Product Groups Product(s): PY0100 2-Propionylpyrrole 98% F&F
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 16-69460 2-PROPIONYL PYROLLE
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Robinson Brothers Limited Providing Excellence in Chemistry Award-winning UK chemical manufacturer of chemical intermediates and high-impact aroma chemicals. Based in the UK, Robinson Brothers is an award-winning chemical manufacturer of chemical intermediates and high-impact aroma chemicals. Robinson Brothers serve many industry sectors across the globe, include: flavour/fragrance, pharmaceutical, agrochemical and material sciences. Our team of Chemists are experts in custom synthesis, contract manufacture and process optimisation. Email: Info Email: Sales Voice: +44 (0)121 553 2451 Fax: +44 (0)121 500 5183 Twitter Linkedin News And Exhibitions Custom Synthesis Industries And Applications https://www.robinsonbrothers.uk/chemistry-competences Products List: View Product(s): PY0100 2-Propionylpyrrole F&F
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R C Treatt and Co Ltd Innovative ingredient solutions World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries. We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products. Email: Enquiries US Email: Enquiries Voice: +44 (0) 1284 702500 Fax: +44 (0) 1284 703809 US Voice: +1 863 668 9500 US Fax: +1 863 668 3388 Twitter Linkedin Youtube News Product(s): 2-Propionylpyrrole Halal, Kosher
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| CAS Number: | 1073-26-3 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 214-026-7 | |
| FDA UNII: | HGS11XF57F | |
| Nikkaji Web: | J87.529E | |
| Beilstein Number: | 0108936 | |
| MDL: | MFCD01696449 | |
| CoE Number: | 11942 | |
| XlogP3: | 1.40 (est) | |
| Molecular Weight: | 123.15493000 | |
| Formula: | C7 H9 N O | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1319 2-propionylpyrrole |
| DG SANTE Food Flavourings: | 14.068 2-propionylpyrrole |
| FEMA Number: | 3614 2-propionylpyrrole |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 1073-26-3 ; 2-PROPIONYLPYRROLE |
Physical Properties:
| Appearance: | white crystals (est) |
| Assay: | 99.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 43.00 to 45.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 230.00 to 232.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.051000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 215.00 °F. TCC ( 101.67 °C. ) |
| logP (o/w): | 1.420 (est) |
| Soluble in: | |
| alcohol | |
| water, slightly | |
| water, 1.238e+004 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: popcorn | |
| roasted popcorn | |
| Odor Description: at 1.00 % in dipropylene glycol. | roast popcorn |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| 2-Propionylpyrrole |
| Endeavour Specialty Chemicals |
| 2-Propionylpyrrole 98% F&F |
| Speciality Chemical Product Groups |
| Parchem |
| 2-propionyl pyrrole |
| Penta International |
| 2-PROPIONYL PYROLLE |
| R C Treatt & Co Ltd |
| 2-Propionylpyrrole
Halal, Kosher |
| Robinson Brothers |
| 2-Propionylpyrrole F&F |
| https://www.robinsonbrothers.uk/chemistry-competences |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 2-Propionylpyrrole |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| 2-Propionylpyrrole |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 [sex: M,F] 1620 mg/kg (Moran et al., 1980) oral-mouse LD50 1620 mg/kg Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | flavoring agents | ||
| Recommendation for 2-propionyl pyrrole usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 2.00 (μg/capita/day) | ||
| Structure Class: | II | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 12 | |||
| Click here to view publication 12 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 0.20000 | |
| beverages(nonalcoholic): | - | - | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | 0.20000 | |
| cheese: | - | 0.10000 | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | 0.20000 | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | 0.20000 | |
| hard candy: | - | 0.20000 | |
| imitation dairy: | - | 0.10000 | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | 0.10000 | |
| milk products: | - | - | |
| nut products: | - | 0.10000 | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | 0.10000 | |
| soft candy: | - | - | |
| soups: | - | 0.10000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 24 (FGE.24): Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf | |
| Pyridine, pyrrole, indole and quinoline derivatives from chemical group 28 Flavouring Group Evaluation 24, Revision 1 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf | |
| Flavouring Group Evaluation 77 (FGE77) [1] - Consideration of Pyridine, Pyrrole and Quinoline Derivatives evaluated by JECFA (63rd meeting) structurally related to Pyridine, Pyrrole, Indole and Quinoline Derivatives evaluated by EFSA in FGE.24Rev1 (2008) View page or View pdf | |
| Statement on List of Representative Substances for Testing.
The current Statement lays down a list of substances in sub-groups with representative substances for which additional data are required prior to their evaluation through the Procedure (Regulation (EC) No 1565/2000). View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 77, Revision 2 (FGE.77Rev2): Consideration of Pyridine, Pyrrole and Quinoline Derivatives evaluated by JECFA (63rd meeting) structurally related to Pyridine, Pyrrole, Indole and Quinoline Derivatives evaluated by EFSA in FGE.24Rev2 (2013) View page or View pdf | |
| Scientific opinion on flavouring group evaluation 77, revision 3 (FGE.77Rev3): consideration of pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63rd meeting) structurally related to pyridine, pyrrole, indole and quinoline derivatives evaluated by EFSA in FGE.24Rev2 View page or View pdf | |
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 61260 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| 1-(1H-pyrrol-2-yl)propan-1-one | |
| Chemidplus: | 0001073263 |
References:
| 1-(1H-pyrrol-2-yl)propan-1-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 1073-26-3 |
| Pubchem (cid): | 61260 |
| Pubchem (sid): | 135017015 |
| Flavornet: | 1073-26-3 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| HMDB (The Human Metabolome Database): | HMDB32492 |
| FooDB: | FDB010140 |
| Export Tariff Code: | 2933.99.8090 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
| For Odor | ||
| caramellic | ||
| caramellic | ||
| geranyl crotonate | FR | |
| popcorn pyrimidine | FL/FR | |
| herbal | ||
| acorn acetate | FR | |
| nutty | ||
| 3- | acetyl pyridine | FL/FR |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| filbert pyrazine | FL/FR | |
| 5- | methyl quinoxaline | FL/FR |
| nutty quinoxaline | FL/FR | |
| popcorn | ||
| 2- | acetyl pyrazine | FL/FR |
| 2- | acetyl pyridine | FL/FR |
| 2- | acetyl thiazole | FL/FR |
| sulfurous | ||
| dimethyl sulfide | FL/FR | |
| For Flavor | ||
| No flavor group found for these | ||
| 2- | acetyl-5-methyl pyrazine | FL |
| 2- | acetyl-6-methyl pyrazine | FL |
| ethyl dimethyl pyrazine | FL | |
| ammoniacal | ||
| 2- | methyl piperidine | FL |
| bready | ||
| 2- | propionyl thiazole | FL |
| corn | ||
| 2- | acetyl pyridine | FL/FR |
| 2- | acetyl thiazole | FL/FR |
| 2- | acetyl-2-thiazoline | FL |
| popcorn pyrimidine | FL/FR | |
| malty | ||
| yeast thiazoline | FL | |
| nutty | ||
| 3- | acetyl pyridine | FL/FR |
| 2- | acetyl-3-ethyl pyrazine | FL/FR |
| 2- | acetyl-3,5(or 6)-dimethyl pyrazine | FL/FR |
| filbert pyrazine | FL/FR | |
| 5- | methyl quinoxaline | FL/FR |
| nutty quinoxaline | FL/FR | |
| roasted | ||
| 2- | acetyl pyrazine | FL/FR |
| sulfurous | ||
| dimethyl sulfide | FL/FR | |
Potential Uses:
| popcorn | FL |
Occurrence (nature, food, other): note
| cocoa roasted cocoa Search Trop Picture | |
| coffee Search PMC Picture | |
| filbert roasted filbert Search Trop Picture | |
| peanut roasted peanut Search Trop Picture | |
| pork cooked pork Search PMC Picture | |
| tea green tea Search Trop Picture |
Synonyms:
| ethyl 2-pyrrolyl ketone | |
| 1- | propanone, 1-(1H-pyrrol-2-yl)- |
| 1- | propanone, 1-pyrrol-2-yl- |
| 2- | propionyl pyrolle |
| alpha- | propionyl pyrrole |
| 2- | propionylpyrrole |
| a- | propionylpyrrole |
| 1-(1H- | pyrrol-2-yl) propan-1-one |
| 1-(1H- | pyrrol-2-yl)-1-propanone |
| 1-(1H- | pyrrol-2-yl)propan-1-one |
| 1- | pyrrol-2-ylpropan-1-one |
| pyrrole, 2-propionyl | |
| 1H- | pyrrole, 2-propionyl |
| 1-2- | pyrrolyl-1-propanone |
| 1-(2- | pyrrolyl)-1-propanone |