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Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 85.00 to 100.00 % sum of isomers
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.98000 to 0.99000 @ 25.00 °C.
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| Pounds per Gallon - (est).: | 8.155 to 8.238
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| Refractive Index: | 1.51400 to 1.52000 @ 20.00 °C.
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| Boiling Point: | 349.00 to 350.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.000045 mmHg @ 25.00 °C. (est) |
| Flash Point: | 201.00 °F. TCC ( 93.89 °C. )
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| logP (o/w): | 5.195 (est) |
| Soluble in: |
| | alcohol | | | water, 0.1943 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
| Stability: |
| | acid cleaner | | | alcoholic lotion | | | antiperspirant | | | deo stick | | | detergent | | | fabric softener | | | hard surface cleaner | | | shampoo | | | soap |
Organoleptic Properties:
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| Odor Type: woody |
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| Odor Strength: | medium , recommend smelling in a 10.00 % solution or less |
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| Substantivity: | 96 hour(s) at 100.00 % |
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| | woody ambergris musk vetiver tobacco |
Odor Description: at 10.00 % in dipropylene glycol. | woody ambergris musk vetiver tobacco |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| IFRA Critical Effect: | Dermal sensitization and systemic toxicity |
| IFRA: | View Standard |
| View IFRA Standards Library for complete information. |
| Please review Amendment 49 IFRA documentation for complete information. |
| IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%): |
| Category 1: Products applied to the lips |
| 0.00016 % |
| Category 2: Products applied to the axillae |
| 0.13 % |
| Category 3: Products applied to the face/body using fingertips |
| 0.40 % |
| Category 4: Products related to fine fragrance |
| 2.40 % |
| | Category 5: Products applied to the face and body using the hands (palms), primarily leave-on |
| Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on |
| 0.60 % |
| Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on |
| 0.52 % |
| Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on |
| 0.60 % |
| Category 5D: Baby Creams, baby Oils and baby talc |
| 0.17 % |
| Category 6: Products with oral and lip exposure |
| 0.00016 % |
| | Category 7: Products applied to the hair with some hand contact |
| Category 7A: Rinse-off products applied to the hair with some hand contact |
| 0.87 % |
| Category 7B: Leave-on products applied to the hair with some hand contact |
| 0.87 % |
| Category 8: Products with significant anogenital exposure |
| 0.17 % |
| Category 9: Products with body and hand exposure, primarily rinse off |
| 2.20 % |
| | Category 10: Household care products with mostly hand contact |
| Category 10A: Household care excluding aerosol products (excluding aerosol/spray products) |
| 2.20 % |
| Category 10B: Household aerosol/spray products |
| 4.40 % |
| | Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate |
| Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure |
| 0.17 % |
| Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure |
| 0.17 % |
| Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin |
| No Restriction |
| | Notes: |
| IFRA FLAVOR REQUIREMENTS: |
Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards. |
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| Recommendation for methyl 2,6,10-trimethyl cyclododeca-2,5,9-trienyl ketone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 1-[(2Z,5Z,9Z)-2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl]ethanone |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 28371-99-5 |
| Pubchem (cid): | 6438191 |
| Pubchem (sid): | 135076080 |
Other Information:
Potential Blenders and core components note
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| For Odor |
| No odor group found for these |
| | amber romance fragrance | FR |
| (Z)-iso | ambrettolide | FR |
| amber |
| (Z)- | abienol | FL/FR |
| | acetoxymethyl isolongifolene | FR |
| | amber acetate | FR |
| | amber butanol | FR |
| | amber carane | FR |
| | amber cyclohexanol | FR |
| | amber naphthofuran | FL/FR |
| | amber specialty | FR |
| | ambergris naphthol | FR |
| | ambergris specialty | FR |
| | ambermax 50 (Givaudan) | FR |
| | ambrette seed absolute | FL/FR |
| | ambrette seed oil | FL/FR |
| | ambrette seed oil CO2 extract | FL/FR |
| | ambrette seed oil replacer | FR |
| | ambroxan | FL/FR |
| | ambroxide | FL/FR |
| | cistus ladaniferus resin | FR |
| | formoxymethyl isolongifolene | FR |
| (cis+trans)-6,6a,7,8,9,9a- | hexahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| | hydroxymethyl isolongifolene 50% in dpg | FR |
| | labdanum absolute | FL/FR |
| | muscomer | FR |
| animal |
| 2- | methyl-4-(camphenyl-8) cyclohexanone | FR |
| balsamic |
| | fir carboxylate | FR |
| | mastic gum resin | FR |
| | methyl hydrogenated rosinate | FR |
| | opoponax resin (commiphora erythraea var. glabrescens engler) | FL/FR |
| | opoponax resinoid replacer | FR |
| | oriental specialty | FR |
| | sclareol | FL/FR |
| | styrax resin (liquidambar styraciflua) | FL/FR |
| | styrax resinoid (liquidambar styraciflua) | FL/FR |
| dusty |
| | woody furan | FR |
| floral |
| beta-iso | methyl ionone | FL/FR |
| | orris pyridine 25% IPM | FR |
| fruity |
| | balsam specialty | FR |
| | valeriana officinalis root extract | FL/FR |
| herbal |
| (+)-alpha- | campholenic aldehyde | FL/FR |
| | romanal | FR |
| mossy |
| | moss specialty | FR |
| musk |
| | musk dimethyl indane | FL/FR |
| | musk indane | FR |
| | musk lactone | FR |
| | musk methyl ketone | FR |
| 6,7,8,9- | tetrahydro-7,7,8,9,9-pentamethyl-5H-cyclopenta[H]quinazoline | FR |
| oily |
| | mcp acetate | FR |
| powdery |
| | midnight passion fragrance | FR |
| spicy |
| | angelica seed absolute | FL/FR |
| terpenic |
| | angelica seed oil | FL/FR |
| woody |
| | acetyl cedrene | FR |
| | amber carbinol | FR |
| | amber decatriene | FR |
| | amber dioxane | FR |
| | amber dodecane | FR |
| | amber formate | FR |
| | amber pentadecane | FR |
| | cedarwood oil texas fractions | FR |
| alpha- | cedrene epoxide | FR |
| | cedryl formate | FR |
| | cedryl methyl ether | FR |
| | dragons blood fragrance | FR |
| | frankincense resinoid replacer | FR |
| | georgywood | FR |
| | hydroxyambran | FR |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| (4aR,5R,7aS,9R)- | octahydro-2,2,5,8,8,9a-hexamethyl-4h-4a,9-methanoazuleno(5,6-d)-1,3-dioxole | FR |
| | patchouli woody amber fragrance | FR |
| | sclareolide | FL/FR |
| | tetramethyl-4-methylene-2-heptanol | FR |
| | tobacarol (IFF) | FR |
| | vetiver specialty | FR |
| | woody dioxolane | FR |
| | woody ether | FR |
| | woody nonane (ethoxy) | FR |
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| For Flavor |
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| No flavor group found for these |
| | ambroxide | FL/FR |
| beta-iso | methyl ionone | FL/FR |
| amber |
| | amber naphthofuran | FL/FR |
| | ambrette seed oil | FL/FR |
| | ambrette seed oil CO2 extract | FL/FR |
| | angelica seed oil | FL/FR |
| | labdanum absolute | FL/FR |
| balsamic |
| | opoponax resin (commiphora erythraea var. glabrescens engler) | FL/FR |
| | styrax resin (liquidambar styraciflua) | FL/FR |
| | styrax resinoid (liquidambar styraciflua) | FL/FR |
| fruity |
| | valeriana officinalis root extract | FL/FR |
| green |
| (+)-alpha- | campholenic aldehyde | FL/FR |
| musk |
| | musk dimethyl indane | FL/FR |
| smoky |
| 2- | methoxy-4-vinyl phenol | FL/FR |
| spicy |
| | angelica seed absolute | FL/FR |
| woody |
| (Z)- | abienol | FL/FR |
| | ambrette seed absolute | FL/FR |
| | ambroxan | FL/FR |
| | sclareol | FL/FR |
| | sclareolide | FL/FR |
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Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cyclisone | | | ethanone, 1-(2,6,10-trimethyl-2,5,9-cyclododecatrien-1-yl)- | | | fixamber | | | methyl 2,6,10-trimethyl cyclododeca-2,5,9-trien-1-yl ketone | | | methyl 2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone | | 1-(2,6,10- | trimethyl-2,5,9-cyclododecatrien-1-yl) ethanone | | 1-[(2Z,5Z,9Z)-2,6,10- | trimethylcyclododeca-2,5,9-trien-1-yl]ethanone | | | trimofix |
Articles:
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