aromadendrene
1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene
 
Notes:
None found
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CAS Number: 72747-25-2Picture of molecule3D/inchi
XlogP3-AA: 4.70 (est)
Molecular Weight: 204.35628000
Formula: C15 H24
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 258.10 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.023000 mmHg @ 25.00 °C. (est)
Flash Point: 224.00 °F. TCC ( 106.50 °C. ) (est)
logP (o/w): 6.427 (est)
Soluble in:
 alcohol
 water, 0.07057 mg/L @ 25 °C (est)
Insoluble in:
 water
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Organoleptic Properties:
Odor Description:
woody
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for aromadendrene usage levels up to:
 not for fragrance use.
 
Recommendation for aromadendrene flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 91354
National Institute of Allergy and Infectious Diseases: Data
 1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene
Chemidplus: 0025246279
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References:
 1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 91354
Pubchem (sid): 135049009
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 artemisia campestris spp. glutinosa flower oil italy @ trace%
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 artemisia vestita wall. flower oil @ 10.80%
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 artemisia vestita wall. leaf oil @ 10.70%
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 bay leaf oil @ 0.00-0.09%
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 cajuput oil @ 0.9%
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 champaca absolute (michelia alba dc.) @ 0.05%
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 clary sage oil greece @ 0.10%
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 croton cajucara benth. leaf oil brazil @ 0.30%
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 curry fruit oil india @ <0.05%
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 curry leaf oil india @ 0.10%
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 eucalyptus globulus bicostata oil @ 5.57%
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 eucalyptus globulus bud oil @ 16.57%
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 eucalyptus globulus fruit oil @ 23.33%
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 eucalyptus globulus maidenii f. muell oil @ 12.04%
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 eucalyptus globulus oil @ 12.31%
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 eucalyptus globulus oil burundia @ 3.60%
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 eucalyptus globulus oil zambia @ 0.60%
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 eucalyptus globulus pseudoglobulus oil @ 1.16%
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 ginger root oil brazil @ 0.50%
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 hyptis spicigera lam. oil mali @ trace-0.10%
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 juniper berry oil @ 0.60%
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 lavender oil CO2 extract france @ 1.02%
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 lemon verbena oil turkey @ 0.54%
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 lime oil CO2 extract mexico @ 0.18%
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 lippia aff. gracillis h.b.k. leaf oil brazil @ 0.50%
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 manuka var. eximium oil australia @ trace%
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 manuka var. rotundifolium oil australia @ 0.60%
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 manuka var. scoparium oil new zealand @ 2.09%
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 marjoram oil sweet morocco @ 0.33%
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 mastic fruit oil @ trace%
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 mastic leaf oil @ 0.06%
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 microstrobos fitzgeraldii leaf oil australia @ trace%
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 mikania cordata (burm. f.) b.l. robinson var. cordata leaf oil france @ 0.40%
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 myrtle lemon scented leaf oil australia @ 0.20%
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 oregano oil mexico @ 0.84%
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 phoebe oil brazil @ 0.11%
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 polyalthia australis (benth.) jessup leaf oil australia @ 0.20%
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 prangos uloptera dc. oil iran @ 1.00%
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 prangos uloptera dc. seed oil iran @ trace%
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 sage oil reunion @ 0.10%
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 sage oil spain @ 0.0-0.2%
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 salvia lavandulifolia vahl. leaf oil @ 0.10%
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 sugandha kokila berry oil @ 0.40%
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 sundacarpus amarus (blume) c.n. page leaf oil australia @ 5.90%
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 tagete oil CO2 extract @ 0.33%
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 tea tree oil australia @ 1.61%
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 thyme oil red spain @ trace%
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 vassoura oil @ 3.30%
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 zanthoxylum bracchyacanthum l. leaf oil australia @ 0.20%
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 zanthoxylum nitidum l. leaf oil australia @ 0.80%
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 zanthoxylum ovalifolium l. leaf oil australia @ 0.50%
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Synonyms:
10(14)-aromadendrene
1,1,7-trimethyl-4-methylidene-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulene
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Articles:
PubMed: Synergistic properties of the terpenoids aromadendrene and 1,8-cineole from the essential oil of Eucalyptus globulus against antibiotic-susceptible and antibiotic-resistant pathogens.
PubMed: Induction of defensive response in Eucalyptus globulus plants and its persistence in vegetative propagation.
PubMed: Oligo-carrageenan kappa-induced reducing redox status and increase in TRR/TRX activities promote activation and reprogramming of terpenoid metabolism in Eucalyptus trees.
PubMed: The total synthesis of (-)-aromadendrene.
PubMed: A comparative analysis of essential oils of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. from Vietnam.
PubMed: Single- versus Multiple-Pest Infestation Affects Differently the Biochemistry of Tomato (Solanum lycopersicum 'Ailsa Craig').
PubMed: Composition, in vitro Anti-inflammatory, Antioxidant and Antimicrobial Activities of Essential Oils from Leaf and Twig Parts of Cupressus cashmeriana.
PubMed: Antimicrobial activity of the essential oil of Tetradenia riparia (Hochst.) Codd. (Lamiaceae) against cariogenic bacteria.
PubMed: Bioactivity and chemical characterisation of Lophostemon suaveolens - an endemic Australian Aboriginal traditional medicinal plant.
PubMed: Antimicrobial Potential and Chemical Characterization of Serbian Liverwort (Porella arboris-vitae): SEM and TEM Observations.
PubMed: Biomimetic synthesis of (+)-ledene, (+)-viridiflorol, (-)-palustrol, (+)-spathulenol, and psiguadial A, C, and D via the platform terpene (+)-bicyclogermacrene.
PubMed: Chemical composition of essential oil and in vitro antioxidant activities of the essential oil and methanol extracts of Eucalyptus loxophleba.
PubMed: Three new cembranoid-type diterpenes from Red Sea soft coral Sarcophyton glaucum: isolation and antiproliferative activity against HepG2 cells.
PubMed: Hepatoprotection of sesquiterpenoids: a quantitative structure-activity relationship (QSAR) approach.
PubMed: Anti-inflammatory, antinociceptive activity of an essential oil recipe consisting of the supercritical fluid CO2 extract of white pepper, long pepper, cinnamon, saffron and myrrh in vivo.
PubMed: Influence of combinations of digitonin with selected phenolics, terpenoids, and alkaloids on the expression and activity of P-glycoprotein in leukaemia and colon cancer cells.
PubMed: Assessment of the chemical composition and in vitro antimicrobial potential of extracts of the liverwort Scapania aspera.
PubMed: Volatile organic compounds of conspecific-damaged Eucalyptus benthamii influence responses of mated females of Thaumastocoris peregrinus.
PubMed: Acaricidal activity of essential oils from five endemic conifers of New Caledonia on the cattle tick Rhipicephalus (Boophilus) microplus.
PubMed: Insecticidal and genotoxic activity of Psoralea corylifolia Linn. (Fabaceae) against Culex quinquefasciatus Say, 1823.
PubMed: Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens.
PubMed: Essential oils from five species of Annonaceae from Vietnam.
PubMed: Assessment of Volatile Chemical Composition of the Essential Oil of Jatropha ribifolia (Pohl) Baill by HS-SPME-GC-MS Using Different Fibers.
PubMed: Chemical composition and biological activities of the essential oil from Calamintha nepeta plants from the wild in southern Italy.
PubMed: Bioactive phytochemicals of leaf essential oils of Cinnamomum osmophloeum prevent lipopolysaccharide/D-galactosamine (LPS/D-GalN)-induced acute hepatitis in mice.
PubMed: Synergism of three-drug combinations of sanguinarine and other plant secondary metabolites with digitonin and doxorubicin in multi-drug resistant cancer cells.
PubMed: Digitonin synergistically enhances the cytotoxicity of plant secondary metabolites in cancer cells.
PubMed: Chemotaxonomical markers in essential oil of Murraya koenigii.
PubMed: [GC-MS study on fingerprint of volatile oil from Kadsura heteroclita].
PubMed: Essential oil composition of Eucalyptus procera Dehnh. leaves from central Iran.
PubMed: Changes in volatile compound composition of Antrodia camphorata during solid state fermentation.
PubMed: Volatile compounds in the stem bark of Sclerocarya birrea (Anacardiaceae) possess antimicrobial activity against drug-resistant strains of Helicobacter pylori.
PubMed: Helichrysum gymnocephalum essential oil: chemical composition and cytotoxic, antimalarial and antioxidant activities, attribution of the activity origin by correlations.
PubMed: Chemical composition and antioxidant, antimicrobial, and larvicidal activities of the essential oils of Annona salzmannii and A. pickelii (Annonaceae).
PubMed: Variation in volatile leaf oils of five Eucalyptus species harvested from Jbel Abderrahman arboreta (Tunisia).
PubMed: Comparison of Eucalyptus cinerea essential oils produced by hydrodistillation and supercritical carbon dioxide extraction.
PubMed: Allelochemical effects of volatile compounds and organic extracts from Muscodor yucatanensis, a tropical endophytic fungus from Bursera simaruba.
PubMed: Induction of sesquiterpenes, phytoesterols and extracellular pathogenesis-related proteins in elicited cell cultures of Capsicum annuum.
PubMed: A chemical marker proposal for the Lantana genus: composition of the essential oils from the leaves of Lantana radula and L. canescens.
PubMed: Variation in volatile leaf oils of twelve eucalyptus species harvested from Hajeb Layoun arboreta (Tunisia).
PubMed: Variability of the needle essential oils of Pinus heldreichii from different populations in Montenegro and Serbia.
PubMed: [Study of chemical constituents of essential oil from flowers of Mikania micrantha H.B.K].
PubMed: Structure-activity relationships of aromadendranes in uterus-relaxant activity.
PubMed: Biotransformation of terpenoids by mammals, microorganisms, and plant-cultured cells.
PubMed: Determination of specific volatile organic compounds synthesised during Tuber borchii fruit body development by solid-phase microextraction and gas chromatography/mass spectrometry.
PubMed: Analysis of atmospheric sesquiterpenes: sampling losses and mitigation of ozone interferences.
PubMed: Antimicrobial activity and chemical composition of Senecio sandrasicus on antibiotic resistant staphylococci.
PubMed: The chemical composition of the essential oils of Euphorbia caracasana and E. cotinifolia (Euphorbiaceae) from Venezuela.
PubMed: Detailed analysis of the essential oil from Cistus albidus L. by combination of GC/RI, GC/MS and 13C-NMR spectroscopy.
PubMed: Chemical composition, antifungal and antitumor properties of ether extracts of Scapania verrucosa Heeg. and its endophytic fungus Chaetomium fusiforme.
PubMed: Chemical constituents and larvicidal property of the essential oil of Blumea mollis (D. Don) Merr. against Culex quinquefasciatus.
PubMed: Volatile constituents from the leaves of Callicarpa japonica Thunb. and their antibacterial activities.
PubMed: Composition and antimicrobial activity of the essential oil of Hypericum rumeliacum subsp. apollinis (Boiss. & Heldr.).
PubMed: Monitoring and fast detection of mycotoxin-producing fungi based on headspace solid-phase microextraction and headspace sorptive extraction of the volatile metabolites.
PubMed: The stereochemistry of ledol from Renealmia chrysotrycha: an NMR study.
PubMed: Chemical, physical and antimicrobial properties of essential oils of Leptospermum scoparium and Kunzea ericoides.
PubMed: Melaleuca oil (tea tree oil) dermatitis.
PubMed: [Analysis of chemical constituent of essential oil in Lonicera japonnica Thunb. cultivated on the northern plain of Henan Province].
PubMed: Variability of the needle essential oils of Pinus peuce from different populations in Montenegro and Serbia.
PubMed: Comparative study on volatile components of Nardostachys rhizome.
PubMed: Composition of Eucalyptus camaldulensis volatiles using direct thermal desorption coupled with comprehensive two-dimensional gas chromatography-time-of-flight-mass spectrometry.
PubMed: Bullatenone, 1,3-dione and sesquiterpene chemotypes of Lophomyrtus species.
PubMed: [Gas chromatography for analysis of essential oils. Characteristics of essential oil of Dracocephalum species and the influence of extraction method on its composition].
PubMed: [Headspace solid-phase microextraction-gas chromatography-mass spectrometry for analysis of volatile components from Atractlodes macrocephala Koidz].
PubMed: Effect of intraspecific competition and substrate type on terpene emissions from some Mediterranean plant species.
PubMed: Comparison of eucalyptus camaldulensis Dehn. oils from Mozambique as obtained by hydrodistillation and supercritical carbon dioxide extraction.
PubMed: The steam volatile oil of Wollemia nobilis and its comparison with other members of the Araucariaceae (Agathis and Araucaria).
PubMed: Solid phase microextraction of volatile constituents from individual fresh Eucalyptus leaves of three species.
PubMed: Diversity in cyclic sesquiterpene production by Gossypium hirsutum.
PubMed: Composition of essential oils of Laurus nobilis, L. nobilis var. angustifolia and Laurus azorica.
PubMed: Chemical studies of marine invertebrates. XXVII. On the absolute configuration of aromadendrane sesquiterpenes from the soft coral Cespitularia aff. subviridis.
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