Articles:
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2H-2,4a-methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-, (2S,4aR)-
Notes:
None found
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Foreverest Resources Ltd. Leading pine based chemicals supplier Supplying turpentine based and natural/extracted flavor & fragrance ingredients. FOREVERESTA® F&F RAW MATERIALS is a range of natural extracts and synthetic aroma chemicals based on the rich material resources and great supply network from China, which was applied for specialty chemicals industry. The markets cover application areas on food, beverage, custom fragrance, fine perfume, personal care, cosmetics, etc. Foreverest Resources Ltd. is a materials supplier, exporting gum turpentine based, terpene derivertives and natural/extracted monomers and intermediates from China since 1988. We offers high quality raw materials for flavors and fragrances synthetic manufacturing in the world. Email: Info Email: Sales Voice: +86 (0)592 5105533 Fax: +86 (0)592 5151667 foreverest 
Linkedin News Products List: View Product(s): Isolongifolene 85% Isolongifolene has woody and amber incense odors, has been widely used as fragrances in cosmetics, perfumers, space sprays, detergents, deodorants, fabrics, fibers, and soap, tobacco, creams, paper products. In addition, Isolongifolene inhibits tyrosinase that is multifunctional copper-containing enzyme for melanin biosynthesis in plants and animals, also, hydrogenated Isolongifolene has been used as a bridged core to prepare a chiral ligand for the estrogen receptor that could be useful in regulating fertility, preventing, and treating breast cancer, and for menopausal hormone replacement. Isolongifolene also used as a natural insecticide and pesticide.
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Lluch Essence S.L. A family company dedicated to sales and distribution Flexibility, availability, price and quality. Flexibility, availability, price and quality make LLUCH ESSENCE S.L. one of Europe’s references when it comes to essential oils and aroma chemicals, and it is now well known all around the world. Email: Info Voice: 34 93 379 38 49 Fax: 34 93 370 65 04 Linkedin Product(s): ISOLONGIFOLENE
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Moellhausen S.P.A. THE CHEMISTRY OF EMOTIONS Innovation and commitment in the name of excellence. After 50 years in business, Moellhausen stands out as one of the world’s leading family-run companies in the industry of flavors and fragrances, raw materials, and specialties. Voice: +39 039.685.6262 Fax: +39 039.685.6263 Facebook Twitter Linkedin Youtube A network of knowledge to grow together Sustainability is at the foundation of a Pervasive technology and total control Product(s): 103475 IsoLONGIFOLENE
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 09-49625 ISOLONGIFOLENE
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SRS Aromatics Ltd For over 25 years Bringing flavour and fragrance into your world. As suppliers / distributors of ingredients to the fragrance and flavour industries, our goal is to provide high quality materials at competitive prices with an exceptional level of service. Established in 1984, SRS Aromatics Ltd is an independent family owned business which has become very well-respected within the fragrance and flavour industry as a reliable and trustworthy partner. Over the years this has allowed the company to develop strong relationships with many global manufacturers; several of whom we represent in the UK. A core aim of our business is to work extremely closely with both our suppliers and customers to maximise service levels with minimum disruption to supply. Email: Info Email: Sales Voice: +44 (0) 1284 704076 Fax: +44 (0) 1284 760819 Twitter Linkedin News Product(s): ISOLONGIFOLENE
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| CAS Number: | 1135-66-6 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 214-494-2 | |
| Beilstein Number: | 2207559 | |
| MDL: | MFCD00042616 | |
| XlogP3-AA: | 5.00 (est) | |
| Molecular Weight: | 204.35628000 | |
| Formula: | C15 H24 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
| EFSA/JECFA Comments: | No longer supported by Industry (DG SANCO, 2012). | |
Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 % sum of isomers |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.92600 to 0.93200 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 7.705 to 7.755 |
| Refractive Index: | 1.49500 to 1.50100 @ 20.00 °C. |
| Boiling Point: | 255.00 to 257.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.014000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 216.00 °F. TCC ( 102.22 °C. ) |
| logP (o/w): | 6.150 (est) |
| Soluble in: | |
| alcohol | |
| water, 0.1401 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor Type: woody | |
| woody dusty amber incense | |
| Odor Description: at 100.00 %. | woody dusty amber incense |
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
perfuming agents |
Suppliers:
| Anhui Haibei |
| isoLongifolene
Odor: Pine woody |
| ExtraSynthese |
| For experimental / research use only. |
| isoLongifolene (GC) ≥98% (sum of enantiomers) |
| Foreverest Resources |
| Isolongifolene 85%
Odor: characteristic Use: Isolongifolene has woody and amber incense odors, has been widely used as fragrances in cosmetics, perfumers, space sprays, detergents, deodorants, fabrics, fibers, and soap, tobacco, creams, paper products. In addition, Isolongifolene inhibits tyrosinase that is multifunctional copper-containing enzyme for melanin biosynthesis in plants and animals, also, hydrogenated Isolongifolene has been used as a bridged core to prepare a chiral ligand for the estrogen receptor that could be useful in regulating fertility, preventing, and treating breast cancer, and for menopausal hormone replacement. Isolongifolene also used as a natural insecticide and pesticide. |
| Fuzhou Farwell |
| Iso Longifolene 75%/80% |
| Lluch Essence |
| ISOLONGIFOLENE |
| Moellhausen |
| IsoLONGIFOLENE
Odor: soft woody, slightly dusty |
| Penta International |
| ISOLONGIFOLENE |
| Reincke & Fichtner |
| isoLongifolene |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| (-)-isoLongifolene ≥91% |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| (-)-Isolongifolene ≥98.0% (sum of enantiomers, GC) |
| SRS Aromatics |
| ISOLONGIFOLENE |
Safety Information:
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
|
R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | fragrance agents | ||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for (-)-isolongifolene usage levels up to: | |||
| 4.0000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) | ||
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3500 (μg/person/day) | ||
| Threshold of Concern: | 1800 (μg/person/day) | ||
| Structure Class: | I | ||
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). | |||
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. | |||
| average usage mg/kg | maximum usage mg/kg | ||
| Dairy products, excluding products of category 02.0 (01.0): | 7.00000 | 35.00000 | |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 5.00000 | 25.00000 | |
| Edible ices, including sherbet and sorbet (03.0): | 10.00000 | 50.00000 | |
| Processed fruit (04.1): | 7.00000 | 35.00000 | |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - | |
| Confectionery (05.0): | 10.00000 | 50.00000 | |
| Chewing gum (05.0): | - | - | |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 5.00000 | 25.00000 | |
| Bakery wares (07.0): | 10.00000 | 50.00000 | |
| Meat and meat products, including poultry and game (08.0): | 2.00000 | 10.00000 | |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 2.00000 | 10.00000 | |
| Eggs and egg products (10.0): | - | - | |
| Sweeteners, including honey (11.0): | - | - | |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 5.00000 | 25.00000 | |
| Foodstuffs intended for particular nutritional uses (13.0): | 10.00000 | 50.00000 | |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 5.00000 | 25.00000 | |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 10.00000 | 50.00000 | |
| Ready-to-eat savouries (15.0): | - | - | |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 | |
Safety References:
| European Food Safety Athority(EFSA): | Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): | |
| Flavouring Group Evaluation 25, (FGE.25)[1] - Aliphatic and aromatic hydrocarbons from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf | |
| Flavouring Group Evaluation 78 (FGE.78)[1] - Consideration of Aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25 - Scientific Opinion of the Panel on Food Additives,Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 25Rev1: Aliphatic and aromatic hydrocarbons from chemical group 31 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 78, Revision 1 (FGE.78Rev1): Consideration of aliphatic and alicyclic and aromatic hydrocarbons evaluated by JECFA (63rd meeting) structurally related to aliphatic and aromatic hydrocarbons evaluated by EFSA in FGE.25Rev2 View page or View pdf | |
| Scientific Opinion on Flavouring Group Evaluation 25, Revision 2 (FGE.25Rev2): Aliphatic and aromatic hydrocarbons from chemical group 31 View page or View pdf | |
| Scientific opinion on Flavouring Group Evaluation 25, Revision 3 (FGE.25Rev3): Aliphatic hydrocarbons from chemical group 31 View page or View pdf | |
| EPI System: | View |
| EPA Substance Registry Services (TSCA): | 1135-66-6 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 102562 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WISER: | UN 2319 |
| WGK Germany: | 3 |
| (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene | |
| Chemidplus: | 0001135666 |
References:
| (2S)-1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 1135-66-6 |
| Pubchem (cid): | 102562 |
| Pubchem (sid): | 135058579 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
Potential Blenders and core components note
| For Odor | ||
| aldehydic | ||
| 2- | methyl undecanal dimethyl acetal | FR |
| amber | ||
| amber decane | FR | |
| cistus ladaniferus absolute resin | FL/FR | |
| balsamic | ||
| mastic gum resin | FR | |
| opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR | |
| opoponax absolute replacer | FR | |
| opoponax resinoid (commiphora erythraea var. glabrescens engle) | FR | |
| opoponax resinoid replacer | FR | |
| floral | ||
| linalool terpenes | FR | |
| waxy | ||
| tetradecanal | FL/FR | |
| woody | ||
| amber dioxane | FR | |
| amber formate | FR | |
| cedryl methyl ether | FR | |
| frankincense resin | FL/FR | |
| (±)- | tetrahydronootkatone | FL/FR |
| tobacarol (IFF) | FR | |
| For Flavor | ||
| No flavor group found for these | ||
| (±)- | tetrahydronootkatone | FL/FR |
| amber | ||
| cistus ladaniferus absolute resin | FL/FR | |
| balsamic | ||
| opoponax absolute (commiphora erythraea var. glabrescens engle) | FL/FR | |
| fatty | ||
| tetradecanal | FL/FR | |
| woody | ||
| frankincense resin | FL/FR | |
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| juniper branch oil @ 0.50% Data GC Search Trop Picture |
Synonyms:
| 1,3,4,5,6,7- | hexahydro-1,1,5,5-tetramethyl-2H-2,4-methanophthalene |
| (2S,4aR)-1,3,4,5,6,7- | hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene |
| (2S)-1,3,4,5,6,7- | hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalene |
| hexahydrotetramethyl methanonaphthalene | |
| (-)-iso | longifolene |
| iso | longifolene |
| 2H-2,4a- | methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl- |
| 2H-2,4a- | methanonaphthalene, 1,3,4,5,6,7-hexahydro-1,1,5,5-tetramethyl-, (2S,4aR)- |
| 2,2,7,7- | tetramethyl tricyclo(6.2.1(1,8).0(1,6))undec-5-ene |