hop cone oil
volatile oil obtained from the freshly dried membranous cones of the female plants of the hops, humulus lupulus l., cannabidaceae
 
Notes:
tsca definition 2008: extractives and their physically modified derivatives. humulus lupulus, moraceae.
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Name: humulus lupulus l. cone oil
CAS Number: 8007-04-3 
Also Contains: humulus lupulus cone extract
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2580 hop cone oil
FDA:No longer provide for the use of these seven synthetic flavoring substances
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
Insoluble in:
 water
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Organoleptic Properties:
 
Odor Type: herbal
 
 hops  
Odor Description:
hops
 
 
Flavor Type: herbal
 
 hops  
Taste Description:
hops
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: fragrance
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Suppliers:
Payand Betrand
Hop Cone Oil Hungary
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50  3500 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

oral-rat LD50  2700 mg/kg
AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 79, 1967.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -2.90000
beverages(nonalcoholic): -1.70000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -2.20000
condiments / relishes: 20.0000035.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -1.70000
fruit ices: -1.70000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -2.50000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 8007-04-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 humulus lupulus l. cone oil
Chemidplus: 0008007043
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References:
 humulus lupulus l. cone oil
Canada Domestic Sub. List: 8007-04-3
Pubchem (sid): 135306977
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Other Information:
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 humulus lupulus distillatesFL/FR
green
 hop oil CO2 extractFL/FR
herbal
 hop absoluteFL/FR
 hop fragranceFR
 hop oilFL/FR
 hop oleoresinFL/FR
 humulus lupulus cone extractFL/FR
woody
 humulus lupulus extractFL/FR
 humulus lupulus tinctureFL/FR
yeasty
 beer CO2 extractFL/FR
 beer extractCS
 
For Flavor
 
herbal
herbal
 beer flavorFL
 hop absoluteFL/FR
 hop flavorFL
 hop oilFL/FR
 hop oleoresinFL/FR
 humulus lupulus cone extractFL/FR
 humulus lupulus distillatesFL/FR
 humulus lupulus extract modifiedFL
 humulus lupulus extract solidFL
 humulus lupulus tinctureFL/FR
malty
 yeast thiazolineFL
spicy
 hop oil CO2 extractFL/FR
woody
 humulus lupulus extractFL/FR
yeasty
 beerFL
 beer CO2 extractFL/FR
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 hop
Search Trop  Picture
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Synonyms:
 hop cone oil
 humulus lupulus cone oil
 volatile oil obtained from the freshly dried membranous cones of the female plants of the hops, humulus lupulus l., cannabidaceae
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Articles:
PubMed: Quantitative genetic parameters for yield, plant growth and cone chemical traits in hop (Humulus lupulus L.).
PubMed: Antiadherent and antibiofilm activity of Humulus lupulus L. derived products: new pharmacological properties.
PubMed: Quantitative trait loci in hop (Humulus lupulus L.) reveal complex genetic architecture underlying variation in sex, yield and cone chemistry.
PubMed: Increase in cone biomass and terpenophenolics in hops ( Humulus lupulus L.) by treatment with prohexadione-calcium.
PubMed: The extract from hop cones (Humulus lupulus) as a modulator of oxidative stress in blood platelets.
PubMed: Varietal characterization of hop (Humulus lupulus L.) by GC-MS analysis of hop cone extracts.
PubMed: Capillary zone electrophoresis method for determination of bitter (alpha- and beta-) acids in hop (Humulus lupulus L.) cone extracts.
PubMed: Effects of powdery mildew fungicide programs on twospotted spider mite (Acari: Tetranychidae), hop aphid (Hemiptera: Aphididae), and their natural enemies in hop yards.
PubMed: DNA sequence and expression variation of hop (Humulus lupulus) valerophenone synthase (VPS), a key gene in bitter acid biosynthesis.
PubMed: Gold binding by native and chemically modified hops biomasses.
PubMed: Efficient extraction of high-quality total RNA from various hop tissues (Humulus lupulus L.).
PubMed: Comparative chemical attributes of native North American hop, Humulus lupulus var. lupuloides E. Small.
PubMed: Phlorisovalerophenone synthase, a novel polyketide synthase from hop (Humulus lupulus L.) cones.
PubMed: [The influence of gibberellic acid on the flower and cone development in hop (Humulus lupulus L.)].
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