|
Category: fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | dark brown semi-solid (est) |
| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | alcohol |
| Insoluble in: |
| | water |
Organoleptic Properties:
| |
| Odor Type: tonka |
| |
| Odor Strength: | medium |
| |
| | sweet herbal rooty tonka coumarinic tobacco |
Odor Description: at 100.00 %. | sweet herbal rooty coumarin tobacco |
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
Safety Information:
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 22 - Harmful if swallowed. S 36 - Wear suitable protective clothing.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | fragrance agents |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only) |
| coumarin | Max. Found: <45.00 % and Reason: Sensitization |
| Recommendation for melilot absolute usage levels up to: | | | 0.8000 % in the fragrance concentrate.
|
| |
| Recommendation for melilot absolute flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| EPA Substance Registry Services (TSCA): | 8023-73-2 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| National Institute of Allergy and Infectious Diseases: | Data |
| | melilotus officinalis absolute |
| Chemidplus: | 0008023732 |
References:
| | melilotus officinalis absolute |
| Canada Domestic Sub. List: | 8023-73-2 |
| Pubchem (sid): | 135343961 |
Other Information:
| Export Tariff Code: | 3301.90.5000 |
| Wikipedia: | View |
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | brachylobus officinalis absolute | | sweet | clover absolute | | | melilot abs BM 01 | | | melilot HT absolute | | | melilotus arvensis absolute | | | melilotus graveolens absolute | | | melilotus officinalis absolute | | | melilotus officinalis fo. suaveolens absolute | | | melilotus pallidus absolute | | | melilotus suaveolens absolute | | | sertula officinalis absolute | | | trifolium officinale absolute |
Articles:
| PubMed: | [Allelopathic effects of the humus soils from Betula platyphylla and Quercus liaotungensis pure plantations on 9 kinds of common shrubs and herbs]. |
| PubMed: | In vitro screening of forty medicinal plant extracts from the United States Northern Great Plains for anthelmintic activity against Haemonchus contortus. |
| PubMed: | Fatty acids, α-tocopherol, β-carotene, and lutein contents in forage legumes, forbs, and a grass-clover mixture. |
| PubMed: | The diversity of Rhizobia, Sinorhizobia and novel non-Rhizobial Paenibacillus nodulating wild herbaceous legumes. |
| PubMed: | [Soil and water losses and phosphorus output at the places between ridges in sloping peanut land under different planting modes in Yimeng mountainous area of Shandong Province, East China]. |
| PubMed: | Using the pollen viability and morphology for fluoride pollution biomonitoring. |
| PubMed: | Isolation and characterization of pyrene metabolizing microbial consortia from the plant rhizoplane. |
| PubMed: | Pyrene effects on rhizoplane bacterial communities. |
| PubMed: | Rhizobium tibeticum sp. nov., a symbiotic bacterium isolated from Trigonella archiducis-nicolai (Sirj.) Vassilcz. |
| PubMed: | Stable low molecular weight RNA profiling showed variations within Sinorhizobium meliloti and Sinorhizobium medicae nodulating different legumes from the alfalfa cross-inoculation group. |
| PubMed: | De-inking sludge and phosphorus effects on growth and symbiotic dinitrogen fixation in forage legumes. |
| PubMed: | Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis (L.) Pallas as an alternative to Soxhlet and ultrasound-assisted extraction. |
| PubMed: | The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. |
| PubMed: | Effect of root death and decay on dissipation of polycyclic aromatic hydrocarbons in the rhizosphere of yellow sweet clover and tall fescue. |
| PubMed: | Effectiveness of phytoremediation as a secondary treatment for polycyclic aromatic hydrocarbons (PAHs) in composted soil. |
| PubMed: | Ability of cold-tolerant plants to grow in hydrocarbon-contaminated soil. |
| PubMed: | [Chronic venous insufficiency: an open trial of FLEBS Crema]. |
| PubMed: | Leghaemoglobin oxygenation gradients in alfalfa and yellow sweetclover nodules. |
| PubMed: | Effects of Melilotus officinalis on acute inflammation. |
| PubMed: | [Effectiveness of the combination of alpha tocopherol, rutin, melilotus, and centella asiatica in the treatment of patients with chronic venous insufficiency]. |
| PubMed: | [Lymphedema of the upper extremity in patients operated for carcinoma of the breast: clinical experience with coumarinic extract from Melilotus officinalis]. |
| PubMed: | A new oleanene glucuronide obtained from the aerial parts of Melilotus officinalis. |
| PubMed: | Expression of beta-amylase from alfalfa taproots. |
| PubMed: | A new oleanene glucuronide having a branched-chain sugar from Melilotus officinalis. |
| PubMed: | Importance of Temperature in the Pathology of Meloidogyne hapla and M. chitwoodi on Legumes. |
| PubMed: | [Contribution of a combination of alpha and beta benzopyrones, flavonoids and natural terpenes in the treatment of lymphedema of the lower limbs at the 2d stage of the surgical classification]. |
| PubMed: | [Immunocorrecting, antianemia, and adaptogenic effects of polysaccharides from Melilotus officinalis]. |
| PubMed: | Impact of Multi-year Cropping Regimes on Solanum tuberosum Tuber Yields in the Presence of Pratylenchus penetrans and Verticillium dahliae. |
| PubMed: | Ferric Leghemoglobin in Plant-Attached Leguminous Nodules. |
| PubMed: | Forage intake and digestion by cattle grazing midgrass prairie rangeland or sideoats grama/sweetclover pasture. |
| PubMed: | A PCR-based method of identifying species-specific repeated DNAs. |
| PubMed: | Ultrastructure of fusion products from soybean cell culture and sweet clover leaf protoplasts. |
| PubMed: | Multielement residues in tissues of guinea pigs fed sweet clover grown on fly ash. |
| PubMed: | [Extraction of Melilotus officinalis]. |
| PubMed: | [The anti-inflammatory and anti-edematous effects of coumarins from Melilotus officinalis]. |
| PubMed: | [Effect of coumarin from Melilotus officinalis on the function of the lymphatic vessel]. |
| PubMed: | [Effect of coumarin from Melilotus officinalis on the blood circulation of the dog]. |
| PubMed: | [Experimental lymphostatic encephalopathy as a consequence of cervical lymphangiothrombophlebitis and its therapy by coumarin from Melilotus officinalis]. |
| PubMed: | [Effect of coumarin from Melilotus officinalis on the convulsion threshold of the central nervous system in rats and guinea pigs]. |
| PubMed: | [Effect of pantothenic acid and pyridoxine deficiency on unconditioned reflex activity and its influencing by coumarin from Melilotus officinalis in rats]. |
| PubMed: | [Unconditioned reflex activity in experimental lymphogenic encephalopathy and therapeutic effects thereon by coumarin from Melilotus officinalis]. |
| PubMed: | [Influence of isoniazid (INH) on the central nervous system and the antagonism between isoniazid and pyridoxine as well as pantothenic acid and coumarin from Melilotus officinalis in rats]. |
| PubMed: | [Effect of chlorpromazine on conditioned reflexes and antagonistic activity of coumarin from Melilotus officinalis]. |
| PubMed: | [Effect of deficiency of pantothenic acid and pyridoxine on the function of the central nervous system and its response to coumarin from Melilotus officinalis]. |
| PubMed: | [Decrease of spontaneous motility in experimental lymphogenic encephalopathy and the prophylactic activity of coumarin from Melilotus officinalis]. |
| PubMed: | [Learning ability in experimental lymphogenic encephalopathy, under the influence of coumarin from Melilotus officinalis]. |
| PubMed: | [Conditioned reflex function in experimental lymphogenic encephalopathy and its therapeutic modification by coumarin from Melilotus officinalis]. |
| PubMed: | [LOCAL TREATMENT OF DISEASES OF VARICOSE ORIGIN. CLINICAL EXPERIENCES WITH ESBERIVEN, A MELILOTUS OFFICINALIS PREPARATION]. |
| PubMed: | [Effect of aqueous extracts of Melilotus officinalis on the regenerating liver]. |
| PubMed: | Biosynthesis of the coumarins. Tracer studies on coumarin formation in Hierochloe odorata and Melilotus officinalis. |
| PubMed: | [Effect of Melilotus officinalis tea and its comparison with pelentan]. |
|