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Category: antioxidants and stabilizers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Organoleptic Properties:
| Odor Strength: | low |
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Odor Description: at 100.00 %. | mild menthol |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 36500 mg/kg
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | antioxidants and stabilizers |
| Recommendation for homomenthyl salicylate usage levels up to: | | | not for fragrance use.
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| Recommendation for homomenthyl salicylate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
| | skin conditioning | |
| | u.v. absorbers | |
| | u.v. filters | |
Occurrence (nature, food, other): note
Synonyms:
| | benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester | | | component of coppertone | | | coppertone | | | eusolex | | | filtrosol A | | | heliopan | | | heliophan | | | homosalate | | 2- | hydroxybenzoic acid 3,3,5-trimethylcyclohexyl ester | | homo | menthyl salicylate USP | | | neo heliopan HMS (Symrise) | | | salicylic acid 3,3,5-trimethylcyclohexyl ester | | | salicylic acid, 3,3,5-trimethylcyclohexyl ester | | | salicylic acid, m-homomenthyl ester | | 3,3,5- | trimethylcyclohexyl 2-hydroxybenzoate | | 3,3,5- | trimethylcyclohexyl salicylate | | (3,3,5- | trimethylcyclohexyl) 2-hydroxybenzoate | | | YOS H |
Articles:
| PubMed: | Percutaneous absorption, disposition, and exposure assessment of homosalate, a UV filtering agent, in rats. |
| PubMed: | Simultaneous determination of the UV-filters benzyl salicylate, phenyl salicylate, octyl salicylate, homosalate, 3-(4-methylbenzylidene) camphor and 3-benzylidene camphor in human placental tissue by LC-MS/MS. Assessment of their in vitro endocrine activity. |
| PubMed: | Lichenic extracts and metabolites as UV filters. |
| PubMed: | UV filters, ingredients with a recognized anti-inflammatory effect. |
| PubMed: | Determination of ultraviolet filters in environmental water samples by temperature-controlled ionic liquid dispersive liquid-phase microextraction. |
| PubMed: | Ionic liquid-based ultrasound-assisted dispersive liquid-liquid microextraction followed high-performance liquid chromatography for the determination of ultraviolet filters in environmental water samples. |
| PubMed: | Simultaneous determination of ultraviolet filters in aqueous samples by plunger-in-needle solid-phase microextraction with graphene-based sol-gel coating as sorbent coupled with gas chromatography-mass spectrometry. |
| PubMed: | Determination of ultraviolet filters in water samples by vortex-assisted dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry. |
| PubMed: | An overview of UV-absorbing compounds (organic UV filters) in aquatic biota. |
| PubMed: | Sunscreens: are they beneficial for health? An overview of endocrine disrupting properties of UV-filters. |
| PubMed: | Development and application of a HPLC method for eight sunscreen agents in suncare products. |
| PubMed: | Preparation, characterization and evaluation of sun protective and moisturizing effects of nanoliposomes containing safranal. |
| PubMed: | Fast liquid chromatography-diode array detection assisted by chemometrics for quantification of seven ultraviolet filters in effluent wastewater. |
| PubMed: | Occurrence and profiles of organic sun-blocking agents in surface waters and sediments in Japanese rivers and lakes. |
| PubMed: | Simultaneous determination of some ultraviolet-absorbing chemicals in sunscreen cosmetics using a high-performance liquid chromatography method. |
| PubMed: | On-line renewable solid-phase extraction hyphenated to liquid chromatography for the determination of UV filters using bead injection and multisyringe-lab-on-valve approach. |
| PubMed: | Does saffron have antisolar and moisturizing effects? |
| PubMed: | Determination of selected UV filters in indoor dust by matrix solid-phase dispersion and gas chromatography-tandem mass spectrometry. |
| PubMed: | Non-porous membrane-assisted liquid-liquid extraction of UV filter compounds from water samples. |
| PubMed: | Sensitive determination of salicylate and benzophenone type UV filters in water samples using solid-phase microextraction, derivatization and gas chromatography tandem mass spectrometry. |
| PubMed: | Quercetin and rutin as potential sunscreen agents: determination of efficacy by an in vitro method. |
| PubMed: | Dosage de l'octyl dimethyl PABA, de l'homosalate et de l'octyl salicylate dans les produits de protection solaire. |
| PubMed: | 3,3,5-Trimethylcyclohexanols and derived esters: green synthetic procedures, odour evaluation and in vitro skin cytotoxicity assays. |
| PubMed: | Validation of a HPLC method for simultaneous determination of five sunscreens in lotion preparation. |
| PubMed: | Photoprotective activity of propolis. |
| PubMed: | Study of the efficacy of 18 sun filters authorized in European Union tested in vitro. |
| PubMed: | Determination of UV filters and antimicrobial agents in environmental water samples. |
| PubMed: | Design of a photostabilizer having built-in antioxidant functionality and its utility in obtaining broad-spectrum sunscreen formulations. |
| PubMed: | Spectroscopic and photochemical properties of the lichen compound lobaric acid. |
| PubMed: | Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks. |
| PubMed: | Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays. |
| PubMed: | Determination of sixteen UV filters in suncare formulations by high-performance liquid chromatography. |
| PubMed: | Liquid chromatographic assay for common sunscreen agents: application to in vivo assessment of skin penetration and systemic absorption in human volunteers. |
| PubMed: | Active ingredients in sunscreens act as topical penetration enhancers for the herbicide 2,4-dichlorophenoxyacetic acid. |
| PubMed: | UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay. |
| PubMed: | Skin penetration and sun protection factor of five UV filters: effect of the vehicle. |
| PubMed: | Comments on "In vitro and in vivo estrogenicity of UV screens". |
| PubMed: | Determination of the UV filters worldwide authorised in sunscreens by high-performance liquid chromatography. Use of cyclodextrins as mobile phase modifier. |
| PubMed: | Determination of UV-filters in sunscreens by HPLC. |
| PubMed: | In vitro and in vivo estrogenicity of UV screens. |
| PubMed: | A predictive mouse ear-swelling model for investigating topical photoallergy. |
| PubMed: | Contact photoallergy testing of sunscreens in guinea pigs. |
| PubMed: | Contact dermatitis to homomenthyl salicylate. |
| PubMed: | Influence of sunscreening agents on color stability of tablets coated with certified dyes III: FD&C Yellow No. 6. |
| PubMed: | Detection of pharmaceuticals and other personal care products in groundwater beneath and adjacent to onsite wastewater treatment systems in a coastal plain shallow aquifer. |
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