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Category: food contact resinous and polymeric coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystals (est) |
| Assay: | 99.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.07100 @ 25.00 °C.
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| Melting Point: | 38.00 to 41.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 181.00 to 182.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 104.00 to 105.00 °C. @ 50.00 mm Hg
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| Vapor Pressure: | 0.614000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 175.00 °F. TCC ( 79.44 °C. )
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| logP (o/w): | 1.460 |
| Soluble in: |
| | alcohol | | | water, 2.616e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor Type: phenolic |
| |
| | phenolic plastic rubbery |
Odor Description: at 0.01 % in dipropylene glycol. | phenolic plastic rubber |
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| Advanced Biotech |
| PHENOL NATURAL
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| Alfa Biotechnology |
| For experimental / research use only. |
| Phenol 98%
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| American International Chemical, LLC. |
| Phenol, Loose Crystals
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| Aurochemicals |
| PHENOL, Natural
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| Charkit Chemical |
| PHENOL LOOSE CRYSTALS, ACS
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| Charkit Chemical |
| PHENOL LOOSE CRYSTALS
|
| Charkit Chemical |
| PHENOL, 85% LIQUIFIED
|
| Glentham Life Sciences |
| Phenol, 99.5%, detached crystals, BP, Ph. Eur., USP grade
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| Glentham Life Sciences |
| Phenol, 99%
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| Indis NV |
| For experimental / research use only. |
| Phenol
|
| Indukern F&F |
| PHENOL NATURAL
Odor: POWERFUL, PHENOLIC, MEDICINAL |
| Lluch Essence |
| PHENOL CRYST.
|
| M&U International |
| NAT.PHENOL, Kosher
|
| Myrazine |
| Phenol
Odor: phenolic plastic rubber (in dipropylene alcohol) |
| Penta International |
| PHENOL FUSED CRYSTAL (CONGEALED LIQUID)
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| Penta International |
| PHENOL LIQUID 90% (WITH STABILIZER)
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| Penta International |
| PHENOL LIQUID 90% USP (With Stabilizer)
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| Penta International |
| PHENOL LOOSE CRYSTAL (FREE FLOWING CRYSTALS)
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| Penta International |
| PHENOL NATURAL
|
| Penta International |
| PHENOL USP LOOSE CRYSTALS (Free Flowing Crystals)
|
| Shiva Chemicals and Pharmaceuticals |
| Phenol
|
| Sigma-Aldrich |
| Phenol, ≥99%
|
| Certified Food Grade Products |
| Sigma-Aldrich |
| Phenol, natural, 97%, FG
|
| Sunaux International |
| nat.Phenol
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| TCI AMERICA |
| For experimental / research use only. |
| Phenol >99.5%(GC)
|
| United International |
| Phenol Nat.
|
| Universal Preserv-A-Chem Inc. |
| PHENOL LIQUIFIED, USP 90%
|
| Wedor Corporation |
| PHENOL
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | T - Toxic. |
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R 23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R 34 - Causes burns. R 48 - Danger of serious damage to health by prolonged exposure. R 68 - Possible risk of irreversible effects. S 01/02 - Keep locked up and out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 28 - After contact with skin, wash immediately with plenty of water. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. S 45 - In case of accident or if you feel unwell seek medical advice immediately.
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 317 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Proceedings of the Society for Experimental Biology and Medicine. Vol. 32, Pg. 592, 1935.
oral-mouse LD50 270 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(8), Pg. 6, 1973.
intraperitoneal-rat LD50 127 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(6), Pg. 103, 1976.
oral-cat LDLo 80 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1319, 1935.
oral-dog LDLo 500 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1319, 1935.
parenteral-frog LDLo 290 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
CARDIAC: OTHER CHANGES
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 166, Pg. 437, 1932.
intraperitoneal-guinea pig LDLo 300 mg/kg "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 228, 1955.
oral-human LDLo 140 mg/kg SKIN AND APPENDAGES (SKIN): SWEATING: OTHER
BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 329, 1968.
oral-human LDLo 14000 mg/kg BEHAVIORAL: MUSCLE WEAKNESS
LUNGS, THORAX, OR RESPIRATION: CYANOSIS "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 463, 1969.
oral-mammal (species unspecified) LD50 500 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
intraperitoneal-mouse LD50 180 mg/kg Pharmacologist. Vol. 10, Pg. 172, 1968.
intravenous-mouse LD50 112 mg/kg BEHAVIORAL: TREMOR Quarterly Journal of Pharmacy & Pharmacology. Vol. 12, Pg. 212, 1939.
intraperitoneal-rabbit LDLo 620 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944.
intravenous-rabbit LDLo 180 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944.
oral-rabbit LDLo 420 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944.
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| Dermal Toxicity: |
skin-rabbit LD50 630 mg/kg Union Carbide Data Sheet. Vol. 1/6/1966
subcutaneous-mouse LD50 344 mg/kg Industrial Health. Vol. 5, Pg. 143, 1967.
skin-rat LD50 669 mg/kg KIDNEY, URETER, AND BLADDER: HEMATURIA
SKIN AND APPENDAGES (SKIN): CUTANEOUS SENSITIZATION (EXPERIMENTAL): AFTER TOPICAL EXPOSURE
BEHAVIORAL: TREMOR British Journal of Industrial Medicine. Vol. 27, Pg. 155, 1970.
subcutaneous-rat LD50 460 mg/kg Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 10, Pg. 1, 1963.
subcutaneous-rabbit LDLo 620 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 233, 1944.
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| Inhalation Toxicity: |
inhalation-mouse LC50 177 mg/m3 Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(6), Pg. 103, 1976.
inhalation-rat LC50 316 mg/m3 Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(6), Pg. 103, 1976.
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Safety in Use Information:
| Category: | food contact resinous and polymeric coatings |
| Recommendation for phenol usage levels up to: | | | not for fragrance use.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 5.20 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 1.00 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 4 |
| Click here to view publication 4 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 0.50000 |
| beverages(nonalcoholic): | - | 0.50000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 0.50000 |
| fruit ices: | - | 0.50000 |
| gelatins / puddings: | - | 0.50000 |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 0.50000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
| | antimicrobial agents | |
| | denaturants | |
| | deodorants | |
Occurrence (nature, food, other): note
Synonyms:
| | acid, carbolic | | | acide carbolique | | | acide phenique | | | benzene, hydroxy- | | | benzophenol | | | carbolic acid | | | carbolic oil | | | carbolicum acidum | | | carbolsaeure | | | fenosmolin | | | hydroxy-benzene | | | hydroxybenzene | | | karbolsaeure | | | phenic acid | | | phenic alcohol | | | phenol alcohol | | | phenol loose crystal (free flowing crystals) | | | phenol natural | | | phenosmolin | | | phenyl alcohol | | | phenyl hydrate | | | phenyl hydroxide | | | phenylalcohol | | | phenylic acid |
Articles:
| PubMed: | Isolation, Identification, and Quantification of Lichenysin, a Novel Nonvolatile Compound in Chinese Distilled Spirits. |
| PubMed: | Genetic diversity among mandarins in fruit-quality traits. |
| PubMed: | Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds. |
| PubMed: | Determination of the importance of in-mouth release of volatile phenol glycoconjugates to the flavor of smoke-tainted wines. |
| PubMed: | Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose. |
| PubMed: | Allyl/propenyl phenol synthases from the creosote bush and engineering production of specialty/commodity chemicals, eugenol/isoeugenol, in Escherichia coli. |
| PubMed: | Influence of preheating on antioxidant activity of the water extract from black soybean and color and sensory properties of black soybean decoction. |
| PubMed: | Cytotoxic, anti-carcinogenic and antioxidant properties of the most frequent plant volatiles. |
| PubMed: | Identification of aroma active compounds of cereal coffee brew and its roasted ingredients. |
| PubMed: | Chemical characterization of commercial liquid smoke products. |
| PubMed: | Analysis of organic volatile flavor compounds in fermented stinky tofu using SPME with different fiber coatings. |
| PubMed: | Enzymatic activity and flavor compound production in fermented silver carp fish paste inoculated with douchi starter culture. |
| PubMed: | Assessment of palatability of two sublingual diluents in allergic patients: a prospective pilot study. |
| PubMed: | Flavored waters: influence of ingredients on antioxidant capacity and terpenoid profile by HS-SPME/GC-MS. |
| PubMed: | Key aroma components of a dry-cured sausage with high fat content (sobrassada). |
| PubMed: | Selectable one-dimensional or two-dimensional gas chromatography-olfactometry/mass spectrometry with preparative fraction collection for analysis of ultra-trace amounts of odor compounds. |
| PubMed: | Ewe's diet (pasture vs grain-based feed) affects volatile profile of cooked meat from light lamb. |
| PubMed: | Quality characterization of the new virgin olive oil var. Sikitita by phenols and volatile compounds. |
| PubMed: | Supercritical fluid extraction of peach (Prunus persica) almond oil: process yield and extract composition. |
| PubMed: | Decoding the key aroma compounds of a Hungarian-type salami by molecular sensory science approaches. |
| PubMed: | Enzymatic removal of off-flavors from apple juice. |
| PubMed: | Variability in the release of free and bound hydroxycinnamic acids from diverse malted barley (Hordeum vulgare L.) cultivars during wort production. |
| PubMed: | [Identification of volatile organic compounds in the manures of cow, hog and chicken by solid phase microextraction coupled with gas chromatography/mass spectrometry]. |
| PubMed: | Phenol and terpene quenching of singlet- and triplet-excited states of riboflavin in relation to light-struck flavor formation in beer. |
| PubMed: | Identification of a stale-beer-like odorant in extracts of naturally aged beer. |
| PubMed: | Kinetics and mechanisms of formation of bromophenols during drinking water chlorination: assessment of taste and odor development. |
| PubMed: | Toxicologic evaluation of licorice extract as a cigarette ingredient. |
| PubMed: | Sensory evaluation of the odors produced during bromophenol formation using a multi-level statistical model. |
| PubMed: | Components detected by means of solid-phase microextraction and gas chromatography/mass spectrometry in the headspace of artisan fresh goat cheese smoked by traditional methods. |
| PubMed: | Real-time monitoring of 4-vinylguaiacol, guaiacol, and phenol during coffee roasting by resonant laser ionization time-of-flight mass spectrometry. |
| PubMed: | Two-generation reproduction study and immunotoxicity screen in rats dosed with phenol via the drinking water. |
| PubMed: | Chemical composition and potential health effects of prunes: a functional food? |
| PubMed: | Light reflected from colored mulches affects aroma and phenol content of sweet basil (Ocimum basilicum L.) leaves. |
| PubMed: | Immunochemical identification of hepatic protein adducts derived from estragole. |
| PubMed: | Oxidation of acetophenone by Aspergillus species and their possible contribution to Katsuobushi flavor. |
| PubMed: | Effects of high pressure treatment on the flavour-related components in meat. |
| PubMed: | In vitro studies of biological effects of cigarette smoke condensate. II. Induction of sister-chromatid exchanges in human lymphocytes by weakly acidic, semivolatile constituents. |
| PubMed: | Simple phenol and phenolic compounds in food flavor. |
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