curcuma zedoaria bark extract
zedoary bark extract
 
Notes:
None found
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Name: curcuma zedoaria berg. rosc. bark extract
CAS Number: 84961-49-9 
ECHA EC Number: 284-637-1
Category: flavor and fragrance agents
 
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FEMA Number: 3123 zedoary bark extract
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):84961-49-9 ; ZEDOARY BARK, EXTRACT (CURCUMA ZEDOARIA (BERG.) ROSC.)
FDA Regulation:
FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor Type: woody
 
Odor Strength: medium
 
 zedoary  
Odor Description:
at 100.00 %. 
zedoary
 
 
Flavor Type: woody
 
 zedoary  
Taste Description:
zedoary
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
AIDS Citations: Search
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Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 curcuma zedoaria berg. rosc. bark extract
Chemidplus: 0084961499
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References:
 curcuma zedoaria berg. rosc. bark extract
Pubchem (sid): 135333520
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
Export Tariff Code: 1302.19.0000
Wikipedia: View
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Potential Blenders and core components note
 
For Odor
No odor group found for these
 zedoaryCS
amber
 amber caraneFR
animal
 musk indenofuranFR
anise
 estragon absoluteFR
balsamic
 croton glabellus bark extractFL/FR
 guaiyl acetateFL/FR
 khella oilFR
 myrrh resinoidFR
 opoponax absolute (balsamodendron kafal)FL/FR
 valeriana wallichii root oilFR
floral
 cassis specialtyFR
 mimosa absoluteFL/FR
 mimosa absolute franceFL/FR
 mimosa absolute indiaFL/FR
 rose concrete (rosa centifolia)FR
green
(Z)-3-hexen-1-yl benzoateFL/FR
 octanal diethyl acetalFL/FR
herbal
 acorus calamus rhizome oilFR
sweet basil absoluteFL/FR
 calamintha clinopodium oilFR
 canarium luzonicum oilFL/FR
 clary sage oil franceFL/FR
 dill seed oilFL/FR
 dill seed oil CO2 extractFL/FR
 linalyl acetateFL/FR
 nonisyl acetateFR
curled parsley seed oilFL/FR
 perillaldehydeFL/FR
laevo-perillaldehydeFL/FR
 petroselinum crispum seed oil CO2 extractFL/FR
common tansy flower oilFR
common tansy flower oil dutchFR
 thymolFL/FR
minty
5- and 6-isopropyl-1,3,3-trimethyl bicyclo(2.2.2)-5,7-octadien-2-one 
musk
 musk indanoneFR
orris
 eugenyl formateFL/FR
para-isopropyl acetophenoneFL/FR
peppery
 asarum europaeum oilFR
phenolic
4-methyl-2,6-dimethoxyphenolFL/FR
saffron
 saffron stigmates absoluteFR
spicy
 allspice berry absoluteFL/FR
 allspice leaf oilFL/FR
 anona squamosa leaf oilFR
 artemisia dracunculus herb oilFL/FR
 atractylodes lancea root 
 ayou wood oilFR
 caryophylleneFL/FR
beta-caryophylleneFL/FR
alpha-caryophyllene alcoholFL/FR
 cascarilla oil replacerFL/FR
 cassia bark oil chinaFL/FR
 cassia leaf oilFL/FR
 cinnamon bark oilFL/FR
 cinnamon bark oil (cinnamomum zeylanicum) indiaFL/FR
 cinnamon bark oil ceylonFL/FR
 cinnamon leaf oil ceylonFL/FR
 cinnamon oleoresin ceylonFL/FR
 clove bud absoluteFL/FR
 clove bud oil CO2 extractFL/FR
 croton eluteria bark oilFL/FR
1,5-dimethyl-3-n-pentyl-2-oxabicyclo(2.2.2)octane 
 eugenyl acetateFL/FR
 galangal root oilFL/FR
 ginger oleoresin africaFL/FR
 ginger root oil brazilFL/FR
 ginger root oil chinaFL/FR
 grains of paradise oilFL/FR
 green oxaneFR
 mace absoluteFL/FR
 mace oilFL/FR
 machilus kusanoi leaf oilFR
 machilus kusanoi wood oilFR
 maja fragranceFR
 mastic fruit oil 
ortho-methoxycinnamaldehydeFL/FR
 methyl isoeugenolFL/FR
 myristica fragrans fruit extractFL/FR
 myristica fragrans seed tinctureFL/FR
 nutmeg oilFL/FR
black pepper absoluteFL/FR
 pepper hexanoneFR
black pepper oilFL/FR
black pepper oil CO2 extractFL/FR
 pepper tree berry absoluteFL/FR
 pepper tree berry oilFL/FR
 pepper tree berry oil CO2 extractFL/FR
 piper longum fruit oilFL/FR
 piper longum fruit oil CO2 extractFL/FR
 safroleCS
 spicy carbonateFR
 sugandha kokila berry oilFR
(E)-tiglic acidFL/FR
 turmeric root absoluteFL/FR
 zingiber officinale root extractFL/FR
 zingiber officinale root tinctureFL/FR
terpenic
para-cymeneFL/FR
 juniper branch oilFR
 pine needle oil dwarfFL/FR
thujonic
common tansy leaf oil dutchFR
common tansy oil canadaFR
beta-thujoneFR
vanilla
 vanilla cresolFR
woody
ar-abietatriene 
 caryophyllene alcohol acetateFR
 caryophyllene formateFL/FR
beta-caryophyllene oxideFL/FR
alpha-copaene 
 dacrydium franklinii wood oilFR
 guaiacwood oilFL/FR
 guaiacwood oil 20% in gurjun balsam oilFR
 guaiacyl acetateFL/FR
 hedychium spicatum root oilFR
 jatamansi root oilFR
 juniper berry oleoresinFL/FR
 methyl methylene tricyclodecanolFR
gamma-muurolene 
 patchouli absoluteFR
4-isopropyl phenolFL/FR
 rhubarb oxiraneFR
 sabineneFL/FR
 santal penten-2-olFR
 spikenard oilFL/FR
 spikenard oil CO2 extractFL/FR
 zedoary bark oilFL/FR
 zedoary root oilFL/FR
 zedoary root oil CO2 extractFL/FR
 
For Flavor
 
No flavor group found for these
ar-abietatriene 
 atractylodes lancea root 
alpha-caryophyllene alcoholFL/FR
 caryophyllene formateFL/FR
alpha-copaene 
 croton glabellus bark extractFL/FR
 eugenyl formateFL/FR
 grains of paradise oilFL/FR
 guaiyl acetateFL/FR
 mastic fruit oil 
gamma-muurolene 
 piper longum fruit oil CO2 extractFL/FR
5- and 6-isopropyl-1,3,3-trimethyl bicyclo(2.2.2)-5,7-octadien-2-one 
 spikenard oilFL/FR
 spikenard oil CO2 extractFL/FR
aromatic
laevo-perillaldehydeFL/FR
balsamic
 opoponax absolute (balsamodendron kafal)FL/FR
brown
(E)-tiglic acidFL/FR
burnt
4-isopropyl phenolFL/FR
fatty
(Z)-3-hexen-1-yl benzoateFL/FR
floral
 linalyl acetateFL/FR
green
 canarium luzonicum oilFL/FR
 octanal diethyl acetalFL/FR
herbal
sweet basil absoluteFL/FR
 clary sage oil franceFL/FR
 dill seed oilFL/FR
 dill seed oil CO2 extractFL/FR
curled parsley seed oilFL/FR
 petroselinum crispum seed oil CO2 extractFL/FR
phenolic
4-methyl-2,6-dimethoxyphenolFL/FR
 thymolFL/FR
pine
 pine needle oil dwarfFL/FR
smoky
 prosopis juliflora wood extractFL
solvent
 methyl phenyl sulfideFL
spicy
 allspice berry absoluteFL/FR
 allspice leaf oilFL/FR
 artemisia dracunculus herb oilFL/FR
 caryophylleneFL/FR
beta-caryophylleneFL/FR
 cascarilla oil replacerFL/FR
 cassia bark oil chinaFL/FR
 cassia leaf oilFL/FR
 cinnamon bark oilFL/FR
 cinnamon bark oil (cinnamomum zeylanicum) indiaFL/FR
 cinnamon bark oil ceylonFL/FR
 cinnamon leaf oil ceylonFL/FR
 cinnamon oleoresin ceylonFL/FR
 clove bud absoluteFL/FR
 clove bud oil CO2 extractFL/FR
 cola acuminata seed tinctureFL
 croton eluteria bark oilFL/FR
1,5-dimethyl-3-n-pentyl-2-oxabicyclo(2.2.2)octane 
 eugenyl acetateFL/FR
 galangal root oilFL/FR
 ginger oleoresin africaFL/FR
 ginger root oil brazilFL/FR
 ginger root oil chinaFL/FR
 mace absoluteFL/FR
 mace oilFL/FR
ortho-methoxycinnamaldehydeFL/FR
 methyl isoeugenolFL/FR
 myristica fragrans fruit extractFL/FR
 myristica fragrans seed tinctureFL/FR
 nutmeg oilFL/FR
black pepper absoluteFL/FR
black pepper oilFL/FR
black pepper oil CO2 extractFL/FR
white pepper oleoresinFL
 pepper tree berry absoluteFL/FR
 pepper tree berry oilFL/FR
 pepper tree berry oil CO2 extractFL/FR
 perillaldehydeFL/FR
 piper longum fruit oilFL/FR
para-isopropyl acetophenoneFL/FR
 turmeric oleoresinFL
 turmeric root absoluteFL/FR
 zingiber officinale root extractFL/FR
 zingiber officinale root tinctureFL/FR
terpenic
para-cymeneFL/FR
waxy
 mimosa absoluteFL/FR
 mimosa absolute franceFL/FR
 mimosa absolute indiaFL/FR
woody
beta-caryophyllene oxideFL/FR
 guaiacwood oilFL/FR
 guaiacyl acetateFL/FR
 juniper berry oleoresinFL/FR
 sabineneFL/FR
 zedoary bark oilFL/FR
 zedoary root oilFL/FR
 zedoary root oil CO2 extractFL/FR
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 zedoary bark
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Synonyms:
 curcuma xanthorrhiza bark extract
java turmeric bark extract
 zedoary bark extract
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Articles:
PubMed: Development of diversity-enhanced extracts of Curcuma zedoaria and their new sesquiterpene-like compounds.
PubMed: β-elemene reverses the drug resistance of lung cancer A549/DDP cells via the mitochondrial apoptosis pathway.
PubMed: Cytotoxic Activity from Curcuma zedoaria Through Mitochondrial Activation on Ovarian Cancer Cells.
PubMed: Analysis of heavy metal lead (Pb) levels with Aas in cow's milk by giving cumin (Cuminum cyminum L.), white turmeric (Curcuma zedoaria Rosc.) and mango turmeric (Curcuma mangga Val.).
PubMed: Larvicidal and pupicidal activities of essential oils from Zingiberaceae plants against Aedes aegypti (Linn.) and Culex quinquefasciatus say mosquitoes.
PubMed: Chemical constituents and anticancer activity of Curcuma zedoaria roscoe essential oil against non-small cell lung carcinoma cells in vitro and in vivo.
PubMed: Suppression of benign prostate hyperplasia by Kaempferia parviflora rhizome.
PubMed: Molecular modeling and docking characterization of CzR1, a CC-NBS-LRR R-gene from Curcuma zedoaria Loeb. that confers resistance to Pythium aphanidermatum.
PubMed: In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria.
PubMed: Total and inorganic arsenic contents in some edible zingiberaceous rhizomes in Thailand.
PubMed: Inhibition of vascular endothelial growth factor-mediated angiogenesis involved in reproductive toxicity induced by sesquiterpenoids of Curcuma zedoaria in rats.
PubMed: Functional food quality of Curcuma caesia, Curcuma zedoaria and Curcuma aeruginosa endemic to Northeastern India.
PubMed: Effects of the extracts and an active compound curcumenone isolated from Curcuma zedoaria rhizomes on alcohol-induced drunkenness in mice.
PubMed: Effects of the medicinal plants Curcuma zedoaria and Camellia sinensis on halitosis control.
PubMed: Report: Studies on antibacterial activity of some traditional medicinal plants used in folk medicine.
PubMed: Nutrient and metal analyses of Chinese herbal products marketed for veterinary use.
PubMed: Cytotoxicity of the rhizome of medicinal plants.
PubMed: Cytotoxicity evaluation of Curcuma zedoaria (Christm.) Roscoe fluid extract used in oral hygiene products.
PubMed: Effect of Curcuma zedoaria Rosc root extracts on behavioral and radiology changes in arthritic rats.
PubMed: Contact toxicity, feeding reduction, and repellency of essential oils from three plants from the ginger family (Zingiberaceae) and their major components against Sitophilus zeamais and Tribolium castaneum.
PubMed: Anti-angiogenesis effect of essential oil from Curcuma zedoaria in vitro and in vivo.
PubMed: Potential mechanisms of hypocholesterolaemic effect of Thai spices/dietary extracts.
PubMed: Effect of different ingredients in traditional Korean medicine for human uterine leiomyoma on normal myometrial and leiomyomal smooth muscle cell proliferation.
PubMed: Curcumenol from Curcuma zedoaria: a second monoclinic modification.
PubMed: Pivotal role of curcuminoids on the antimutagenic activity of Curcuma zedoaria extracts.
PubMed: Self-nanoemulsifying drug delivery system (SNEDDS) for oral delivery of Zedoary essential oil: formulation and bioavailability studies.
PubMed: Curcuma zedoaria Rosc. (white turmeric): a review of its chemical, pharmacological and ethnomedicinal properties.
PubMed: Isolation and characterization of antioxidation enzymes from cells of zedoary (Curcuma zedoaria Roscoe) cultured in a 5-l bioreactor.
PubMed: Inhibition of inducible prostaglandin E2 production and cyclooxygenase-2 expression by curdione from Curcuma zedoaria.
PubMed: Aromatic plant-derived essential oil: an alternative larvicide for mosquito control.
PubMed: Larvicidal efficacy and biological stability of a botanical natural product, zedoary oil-impregnated sand granules, against Aedes aegypti (Diptera, Culicidae).
PubMed: Anti-inflammatory sesquiterpenes from Curcuma zedoaria.
PubMed: Comparison of Anti-inflammatory Activities of Six Curcuma Rhizomes: A Possible Curcuminoid-independent Pathway Mediated by Curcuma phaeocaulis Extract.
PubMed: Essential oils as potential adulticides against two populations of Aedes aegypti, the laboratory and natural field strains, in Chiang Mai province, northern Thailand.
PubMed: Seasonal variation and analgesic properties of different parts from Curcuma zedoaria Roscoe (Zingiberaceae) grown in Brazil.
PubMed: Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity.
PubMed: Suppressive effect of Zedoariae rhizoma on pulmonary metastasis of B16 melanoma cells.
PubMed: Anti-babesial compounds from Curcuma zedoaria.
PubMed: The inhibitory effect of a Korean herbal medicine, Zedoariae rhizoma, on growth of cultured human hepatic myofibroblast cells.
PubMed: Antimicrobial activity of Curcuma zedoaria and Curcuma malabarica tubers.
PubMed: [Establishment of high-yield suspension cell line of Curcuma zedoaria (Berg.) Rosc and study on the volatile oil synthesis-controlling with precursors].
PubMed: A curcuminoid and two sesquiterpenoids from Curcuma zedoaria as inhibitors of nitric oxide synthesis in activated macrophages.
PubMed: Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells.
PubMed: Antimicrobial activity and cytotoxicity of the essential oil of Curcuma zedoaria.
PubMed: Effects of Central Kalimantan plant extracts on intraerythrocytic Babesia gibsoni in culture.
PubMed: 9-Oxo-neoprocurcumenol from Curcuma aromatica (Zingiberaceae) as an attachment inhibitor against the blue mussel, Mytilus edulis galloprovincialis.
PubMed: Inhibition of human pathogenic fungi by members of Zingiberaceae used by the Kenyah (Indonesian Borneo).
PubMed: The in vitro inhibitory effects of crude extracts of traditional Chinese herbs on 3-hydroxy-3-methylglutaryl-coenzyme A reductase on Vero cells.
PubMed: [Effect of Curcuma zedoaria (Berg.) Bosc on the myoelectric activity of uterus in rats and study of its mechanisms].
PubMed: Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells.
PubMed: Phytochemical analysis and analgesic properties of Curcuma zedoaria grown in Brazil.
PubMed: Inhibitory effects of natural sesquiterpenoids isolated from the rhizomes of Curcuma zedoaria on prostaglandin E2 and nitric oxide production.
PubMed: Suppressive effect of natural sesquiterpenoids on inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) activity in mouse macrophage cells.
PubMed: Agrotechniques for the cultivation of curcuma zedoaria (berg.) rosc.
PubMed: Effects of polysaccharides from rhizomes of Curcuma zedoaria on macrophage functions.
PubMed: Sesquiterpenoids from the rhizome of Curcuma zedoaria.
PubMed: A curcuminoid and sesquiterpenes as inhibitors of macrophage TNF-alpha release from Curcuma zedoaria.
PubMed: Amylopectin aggregation as a function of starch phosphate content studied by size exclusion chromatography and on-line refractive index and light scattering.
PubMed: Antitumor, genotoxicity and anticlastogenic activities of polysaccharide from Curcuma zedoaria.
PubMed: Antiinflammatory potency of dehydrocurdione, a zedoary-derived sesquiterpene.
PubMed: Inhibitory effect and action mechanism of sesquiterpenes from Zedoariae Rhizoma on D-galactosamine/lipopolysaccharide-induced liver injury.
PubMed: Cytotoxicity of curcuminoids and some novel compounds from Curcuma zedoaria.
PubMed: [Isolation and structure determination of furan sesquiterpene from Chinese traditional herb ezhu (rhizome of Curcuma zedoaria Rosc.)].
PubMed: Multiplication of curcuma species by tissue culture.
PubMed: Antimutagenic activity of extracts from anticancer drugs in Chinese medicine.
PubMed: Toxicity of shoti (Indian arrowroot: Curcuma zedoaria) for rats and chicks.
PubMed: Isolation of Ethyl p-methoxycinnamate, the major antifungal principle of Curcumba zedoaria.
PubMed: [Structure of curzerenone, a new sesquiterpene from Curcuma zedoaria].
PubMed: [Structure of zedoarone, a new sesquiterpene from Curcuma zedoaria].
PubMed: Pharmacological action of some common essential oil-bearing plants used in indigenous medicine. I. Pharmacological action of Acorus calamus, Curcuma zedoaria, Xanthoxylum alatum and Angelica archangelica.
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