2,6-dimethyl pyrazine
2,6-dimethylpyrazine
 
Notes:
Flavour additive and odorant in foods. Present in raw asparagus, baked potato, French fries, wheat bread, crispbread, black or green tea, roasted barley, roasted filberts or pecans, malt, peated malt, wort, wild rice (Zizania aquatica) and squid
  • Advanced Biotech
    • Advanced Biotech. Inc.
      Inspired by Nature
      A diverse range of products, all meeting our stringent commitment to quality.
      Advanced Biotech is a leading manufacturer and supplier of high-quality Natural flavoring ingredients & botanical extracts for the food/beverage, cosmetic and personal care industries. With over 25 years of experience working with Fermentation processing & botanical extracts, we can help develop new innovative and functional products for today’s competitive marketplace. Our company prides itself in the ability to cater to our customer’s specific needs while maintaining our focus on integrity, honesty and the commitment to high quality product standards. We proudly offer our quality Natural ingredients to companies around the world.
      US Email: Info
      US Email: Quotes and Orders
      US Voice: 973-339-6242
      US Fax: 973-256-4101
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      Product(s):
      1497 2,6-DIMETHYL PYRAZINE NATURAL >99% min. (mixed isomers)
      SDS
      4002 2,6 DIMETHYL PYRAZINE
      SDS
       
  • Augustus Oils
    • Augustus Oils Ltd
      The Premier Supplier
      Augustus Oils Ltd, in harmony with nature - to present it at its best...
      A wealth of experience, expertise and knowledge has allowed Augustus to bridge the gulf in expectation and trust between growers and users of natural ingredients. The Company works in partnership with customers on the one hand, and growers, farmers and distillers on the other. Both users and producers can then focus on exactly what they do best, while skilled Augustus technicians closely monitor and control the delivered product. This ensures users can have the confidence that they will receive the best raw materials suited to their requirements.
      Email: Enquiries
      Email: Sales
      Email: web site enquiries
      Voice: +44 (0)1420 590555
      Fax: +44 (0)1420 592420
      Services
      Product(s):
      2 6 Dimethyl Pyrazine
       
  • Beijing Lys Chemicals
    • Beijing Lys Chemicals Co, LTD.
      From Grams to Tons
      Fine chemical high-tech company which contains R&D, production, and sales.
      BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
      Email: Mr. Jia
      Email: Mr. Guo
      Voice: 86-10-68418738
      Fax: 86-10-68418739
      Mr. Guo86-10-68483445
      Mr. Guo86-10-68418739
      News
      Product(s):
      10058 2,6-Dimethylpyrazine
       
  • BOC Sciences
    • BOC Sciences
      Best of Chemicals Supplier
      Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
      BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
      BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
      Email: Marketing
      US Email: Marketing
      Email: Sales
      US Email: Sales
      Voice: 1-631-485-4226
      Fax: 1-631-614-7828
      US Voice: 1-631-485-4226
      US Fax: 1-631-614-7828
      Europe44-203-286-1088
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      Product(s):
      108-50-9 2,6-Dimethylpyrazine
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
      Email: Sales
      Voice: 203-299-3220
      Fax: 203-299-1355
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      Products List: View
      Product(s):
      DIMETHYLPYRAZINE, 2,6- FEMA 3273
       
  • Endeavour Specialty Chemicals
    • Endeavour Specialty Chemicals Ltd
      Expertise in high impact aroma chemicals
      Endeavour Speciality Chemicals offers high-impact aroma chemicals, at small to medium scale.
      Speciality Chemical has more than 25 years experience of manufacturing high-impact aroma chemicals. With our core expertise in sulfur and heterocyclic chemistries, Endeavours products have applications in a range of industry sectors including flavours and fragrances, pharmaceutical research and material sciences. Endeavour also offer custom synthesis and contract manufacturing services at their UK manufacturing site.
      Email: Info
      Email: Sales
      Voice: +44 (0)1327 310 079
      Fax: +44 (0)1327 310 701
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      Speciality Chemical Product Groups
      Product(s):
      PZ0290 2,6-Dimethyl pyrazine
       
  • Excellentia International
    • Excellentia International
      Ingredients by Nature
      Exceptional quality and excellence in meeting our customers requirements.
      Excellentia International was founded in 2010 through the merger of Excellentia Flavors LLC and Polarome International. Collectively, these companies account for more than one hundred years of industry experience, and are recognized for exceptional quality and excellence in meeting our customers’ requirements.
      Email: Info
      Email: Sales
      Email: Regulatory
      Voice: 732.749.9840
      Our Services
      Product(s):
      2,6-Dimethyl Pyrazine (Pyrazine Mix. # 12, 16, 20) Natural
       
  • FCI SAS
    • FCI SAS
      Inspired by Nature
      At FCI customer service is not a department it’s an attitude.
      Our team is composed of motivated professionals with great experience in the flavours and fragrances market. Our company has been serving this industry for more than 40 years and is ISO 9001 certified since 2009 . Whatever your question on flavour and fragrance ingredients: commercial, technical or regulatory – we will answer it very quickly.
      Email: Info
      Email: Philippe Faucher
      US Email: USA Sales
      Email: Germany Sales
      Email: Italy Sales
      Email: Japan Sales
      Voice: +33 (0)1 34 25 58 10
      Fax: + 33 1 34 25 58 18
      About Us
      Product(s):
      50047 2,6-DIMETHYL PYRAZINE
       
  • Frutarom
    • Frutarom (UK) Ltd
      Flavor & Specialty Ingredients
      Your preferred partner for flavour and fragrance success.
      Our broad and diverse product portfolio is designed to provide and cater for every flavor and taste profile required by our customer base and incorporates historic, and iconic, market leading products.
      Email: Info
      US Email: Info- USA
      Email: Sales
      Voice: +44 (0) 1429 863 222
      Products List: View
      Product(s):
      441D010250 26 DIMETHYLPYRAZINE KOSHER
       
  • Indukern F&F
  • Jiangyin Healthway
    • Jiangyin Healthway International Trade Co., Ltd
      Independent Ingredients Supplier
      We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.
      Jiangyin Healthway International Trade Co., Ltd is a professional company, main engaged in manufacturing and exporting aroma chemicals ,food additives , cosmetic ingredient ,pharmaceutical intermediates & other fine chemicals; especially on aroma chemicals , as the major manufacturer of heterocyclic and sulphur aroma compounds , we are the leading independent ingredients supplier to the flavour and fragrance industries in China, can offer hundreds of different high quality aroma chemicals.
      Email: Info
      Email: Sales
      Voice: 86-510-86023169
      Fax: 86-510-86023170
      Mobile0086-13093133011
      Services
      Biochemical
      Natural Food Colour
      New functional food ingredients
      Product(s):
      HL0104 2,6-Dimethyl Pyrazine
       
  • M&U International
    • M&U International LLC
      Steady supply & demand
      Meeting customers increasing demands at home as well as abroad.
      M&U dedicates itself to the development and production of new products as well as continuously promoting those new products. We’ve maintained a steady supply&demand relationship with a large number of manufacturers at home and abroad. We’ve developed an extensive network and because of our relationships with these manufacturers, we’re able to provide a stable supply of great quality materials. We’re located in China’s largest communications hub, Shanghai and in the U.S. near one of the largest sea ports on the East Coast. The strategic locations of our facilities ensure convenient, prompt and secure delivery of our products to our customers.
      Email: Sales
      US Email: Sales
      Voice: +86-21-32515501 60762991 60762992
      Fax: +86-21-32515502 64204960
      US Voice: 908-359-9000
      US Fax: 908-359-9002
      News
      Product(s):
      H0005 2,6-DIMETHYL PYRAZINE, Kosher
       
  • Moellhausen
  • Myrazine
    • Myrazine LLC
      EU Natural Ingredients from Fermentation
      All the materials are sourced from fermentation.
      Myrazine LLC,formerly known as Cheng Smith LLC, and Abioco, started its search for Natural materials in 2000, when we started to import natural alcohols from China. China's liquor fermentation technology is as old as the country. Chinese liquor is? unique, because it is fermented from grains, such as rice, wheat, sorghum, and barleys. With bacteria or microorganism present in the fermentaiton, Chinese liquor is rich in flavours. It is reported that there are over 100 flavour materials in the liquor fermentation broth. During the production, the "good" liquor is distilled out, and the "bad" alcohols are dumped as "wastes" before 1980s. Fusel oil is regarded and dumped as the "bad" one during the production. Today, every single ton of the liquor fermentation "wastes" --- fusel oil, has been physically distilled. Alcohols from these distillations are methyl alcohol, ethanol, propanol, butanol, iso-butanol, iso-amyl alcohol, etc. Most of the alcohols are used by the flavour and fragrances industry as raw materials, which eventually go into the beverages, food, and some daily products. According to the US and EU regulations about natural ingredients, materials from fermentation are regarded as "natural".
      Email: Info
      Email: Sales
      Voice: +1.623 565 7047
      Product(s):
      Pyrazine, 2,6-dimethyl-
       
  • OQEMA
    • OQEMA
      With a focus on providing the highest level of service
      OQEMA has established itself at the forefront of the global chemical industry.
      The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
      Email: Contact Us:
      US Email: Dean Matienzo
      Email: Sales
      US Email: Dean Matienzo - Sales Manager
      Voice: +44 1993 843081
      Fax: +44 1993 841261
      US Voice: +1 973 886 3778
      US Fax: +1 973 346 1106
      Linkedin
      Website
      Global Distribution
      Product(s):
      2,6-Dimethyl Pyrazine
       
  • Synerzine
    • Synerzine, Inc.
      Innovation. Customization. Aroma Ingredients.
      Synerzine is a leading supplier of flavor and fragrance ingredients.
      Synerzine expresses what we have grown to embody as an organization - the synergy and connection between raw ingredients, science, technology, and the final product. Our experienced team is passionate about bringing our customers high-quality innovative ingredients that they can trust.
      Building upon our 44 year history, the Synerzine team provides customers around the globe with convenient access to over 1200 high-quality aroma ingredients. We actively engage with customers to add a wide array of new products and services on a regular basis. Our aim is to delight every customer with our exceptional services, large product selection, customization and the highest quality and safety standards. We provide our customers with true value designed to help them bring their products to market faster.
      US Email: Customer Service
      US Email: Sales
      US Voice: (404) 524-6744
      US Fax: (404) 577-1651
      Inquiry
      Products List: View
      Product(s):
      626 2,6-Dimethylpyrazine
      N626 2,6-DIMETHYLPYRAZINE, NATURAL
       
  • Taytonn
    • TAYTONN PTE LTD
      Supplying Asia Pacific
      We fully understand the demands of the F&F industry and we endeavour to supply quality products, with ready availability and a personalised service.
      Since 2001 TAYTONN has been distributing key ingredients to the Fragrance and Flavor industry in Asia. We work closely with customers, principals and vendors. Together we forecast demand and match it with supply of aroma chemicals, essential oils and natural isolates & extracts. Sourced from around the world, our F&F ingredient inventory in Singapore is ready to ship to any location in Asia and beyond. Time and again, we help our principals introduce new discoveries to the F&F market - stimulating creativity and bringing value added proposition to our customers.
      Email: Info
      Email: Sales
      Voice: + 65 - 6861 8113
      Fax: + 65 - 6861 8115
      Product(s):
      2,6-Dimethylpyrazine
       
  • TCI AMERICA
    • TCI AMERICA
      Moving Your Chemistry Forward
      We continuously strive to advance our technology.
      With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
      Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
      US Email: Sales
      Email: Technical Support
      Voice: 1-800-423-8616
      Fax: 1- 888-520-1075
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      Product(s):
      D1527 2,6-Dimethylpyrazine >98.0%(GC)(T)
       
  • Tianjin Danjun International
    • Tianjin Danjun International Trade Co., LTD.
      Quality Products
      We know the Chinese chemical market well.
      Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
      Email: Info
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      Voice: +86-15822601686
      Products List: View
      Product(s):
      B-008 2,6-Dimethylpyrazine
       
  • R C Treatt & Co Ltd
    • R C Treatt and Co Ltd
      Innovative ingredient solutions
      World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
      We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
      Email: Enquiries
      US Email: Enquiries
      Voice: +44 (0) 1284 702500
      Fax: +44 (0) 1284 703809
      US Voice: +1 863 668 9500
      US Fax: +1 863 668 3388
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      Product(s):
      2,6-Dimethylpyrazine Halal, Kosher
       
  • United International
    • Qingdao Free Trade Zone United International Co Ltd
      Quality Products
      A partner in your supply chain solution.
      Qingdao Free Trade Zone United International Trade Co., Ltd.was founded in 1996, specializing in the production and import and export of food additives,flavor raw materials and pharmaceutical and chemical raw materials. The company has experienced R&D and business personnel,product quality, low price, efficient service and fast insight and grasp the latest market information.
      Email: Info
      Email: Sales
      Voice: +86-532-83893699
      Fax: +86-532-83893695
      Product(s):
      1005 2,6-Dimethyl Pyrazine
      1005N 2,6-Dimethyl Pyrazine Nat.
       
  • Ernesto Ventós
  • Vigon International
    • Vigon International, Inc.
      Passion for Simplicity
      Manufacturer and supplier of high quality flavor and fragrance ingredients.
      The growth and success of Vigon is due in large part to a unique corporate concept that Vigon has developed and established within the industry: Creative Partnerships. This partnership concept has been and continues to be the foundation and guiding principle for all of Vigon's activities.
      US Email: Sales
      US Voice: 570-476-6300
      US Fax: 570-476-1110
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      Products List: View
      Product(s):
      504546 Dimethyl-2,6 Pyrazine
       
  • WholeChem
    • WholeChem, LLC
      Connecting Innovators To the Building Blocks Of the Universe
      Custom manufacturer and distributor of specialty ingredients. We make global local.
      We owe our success to our integrity, our dedication to the industry, and our commitment to our clients. We invite your inquiries regarding our current product list and any other products you may be having trouble sourcing.
      Email: Info
      Email: Orders
      Voice: +1 (262) 995.8668
      Certification
      Products List: View
      Product(s):
      2,6-Dimethylpyrazine
       
Synonyms   Articles   Notes   Search
CAS Number: 108-50-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 203-589-4
FDA UNII: N77Q72C9I3
Nikkaji Web: J1.498B
Beilstein Number: 0107052
MDL: MFCD00006148
CoE Number: 2211
XlogP3: 0.50 (est)
Molecular Weight: 108.14376000
Formula: C6 H8 N2
NMR Predictor: Predict (works with chrome or firefox)
EFSA/JECFA Comments: Mixture of positional isomers (2,5- and 2,6-isomers), 2,5- (35-55 %) and 2,6-isomers (45-65 %) (sum 98 %) (EFFA, 2010a).
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Flavoring: 767  2,6-dimethylpyrazine
DG SANTE Food Flavourings: 14.021  2,6-dimethylpyrazine
FEMA Number: 3273 2,6-dimethylpyrazine
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):108-50-9 ; 2,6-DIMETHYLPYRAZINE
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white to yellow crystals (est)
Assay: 98.00 to 100.00 % 
Additional Assay Information: sum of 2,3- 2,5- and 2,6- isomers
Food Chemicals Codex Listed: Yes
Melting Point: 37.00 to  48.00 °C. @ 760.00 mm Hg
Boiling Point: 154.00 to  155.00 °C. @ 760.00 mm Hg
Vapor Pressure: 3.873000 mmHg @ 25.00 °C. (est)
Flash Point: 127.00 °F. TCC ( 52.78 °C. )
logP (o/w): 0.540
Soluble in:
 alcohol
 essential oils
 water, 3.816e+004 mg/L @ 25 °C (est)
Insoluble in:
 water
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor Type: chocolate
 
Odor Strength: high ,
recommend smelling in a 0.10 % solution or less
 
 cocoa  roasted  nutty  meaty roasted meaty  coffee  
Odor Description:
at 0.10 % in dipropylene glycol. 
cocoa roasted nuts roast beef coffee
 
 
Flavor Type: nutty
 
 nutty  coffee  cocoa  musty  bready  meaty  
Taste Description:
nutty coffee cocoa musty bready meaty
 
Odor and/or flavor descriptions from others (if found).
 
Sigma-Aldrich
2,6-Dimethylpyrazine, ≥98%, FG
Odor Description: meaty; nutty; coffee.
Taste Description: nutty coffee cocoa musty bready meaty
 
Advanced Biotech
2,6 DIMETHYL PYRAZINE
Odor Description: Chocolate, Nutty, Roasted
 
Ernesto Ventós
2,6-DIMETHYLPYRAZINE
Odor Description: ROAST BEEF, COCOA, COFFEE, NUTTY
Taste Description: nutty coffee cocoa musty bready meaty
 
FCI SAS
2,6-DIMETHYL PYRAZINE
Odor Description: Roast, coffee, peanut and meat
Taste Description: nutty coffee cocoa musty bready meaty
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
Advanced Biotech
2,6 DIMETHYL PYRAZINE
Odor: Chocolate, Nutty, Roasted
Advanced Biotech
2,6-DIMETHYL PYRAZINE NATURAL
>99% min. (mixed isomers)
Odor: Chocolate, roasted nuts
Ambles Nature et Chimie
2.6-DIMETHYL PYRAZINE
Anhui Haibei
2,6-Dimethyl Pyrazine
Odor: Cocoa roasted nuts roast beef coffee
Anhui Suzhou Jinli Aromatic Chemicals
2,6-Dimethyl Pyrazine
Odor: roast, coffee, peanut, meat
Augustus Oils
2 6 Dimethyl Pyrazine
Services
Beijing Lys Chemicals
2,6-Dimethylpyrazine
BOC Sciences
For experimental / research use only.
2,6-Dimethylpyrazine
Charkit Chemical
DIMETHYLPYRAZINE, 2,6- FEMA 3273
EMD Millipore
For experimental / research use only.
2,6-Dimethylpyrazine
Endeavour Specialty Chemicals
2,6-Dimethyl pyrazine
Speciality Chemical Product Groups
Ernesto Ventós
2,6-DIMETHYLPYRAZINE
Odor: ROAST BEEF, COCOA, COFFEE, NUTTY
Excellentia International
2,6-Dimethyl Pyrazine (Pyrazine Mix. # 12, 16, 20) Natural
FCI SAS
2,6-DIMETHYL PYRAZINE
Odor: Roast, coffee, peanut and meat
Frutarom
26 DIMETHYLPYRAZINE
KOSHER
Flavor: Roasted, Nutty, Cocoa, Meaty, Coffee
IFF
26 DIMETHYLPYRAZINE
KOSHER
Flavor: Roasted, Nutty, Cocoa, Meaty, Coffee
Indukern F&F
2,6-DIMETHYL PYRAZINE
Odor: NUTTY, COFFEE
Jiangyin Healthway
2,6-Dimethyl Pyrazine
New functional food ingredients
Jinan Enlighten Chemical Technology(Wutong Aroma )
2,6-Dimethyl pyrazine, Kosherk
Kingchem Laboratories
2,6 DIMETHYLPYRAZINE
Odor: Roast, Coffee, Earthnut, Meat
M&U International
2,6-DIMETHYL PYRAZINE, Kosher
Matrix Scientific
For experimental / research use only.
2,6-Dimethylpyrazine, 95+%
Moellhausen
2,6-DIMETHYL PYRAZINE
Myrazine
Pyrazine, 2,6-dimethyl-
Odor: cocoa roasted nuts roast beef coffee
OQEMA
2,6-Dimethyl Pyrazine
Pearlchem Corporation
2,6-Dimethyl Pyrazine
Penta International
2,6-DIMETHYL PYRAZINE
Penta International
2,6-DIMETHYLPYRAZINE NATURAL NEAT
R C Treatt & Co Ltd
2,6-Dimethylpyrazine
Halal, Kosher
Reincke & Fichtner
2,6-Dimethylpyrazine
Riverside Aromatics
2,6-DIMETHYLPYRAZINE
Robinson Brothers
2,6-Dimethyl pyrazine F&F
https://www.robinsonbrothers.uk/chemistry-competences
Santa Cruz Biotechnology
For experimental / research use only.
2,6-Dimethylpyrazine
Sigma-Aldrich
2,6-Dimethylpyrazine natural (US)
Odor: coffee; meaty; nutty
Certified Food Grade Products
Sigma-Aldrich
2,6-Dimethylpyrazine, ≥98%, FG
Odor: meaty; nutty; coffee.
Sunaux International
2,6-Dimethyl Pyrazine
Synerzine
2,6-DIMETHYLPYRAZINE, NATURAL
Synerzine
2,6-Dimethylpyrazine
Taytonn
2,6-Dimethylpyrazine
Odor: Cocoa, Coffee, Meaty, Nutty, Roast
TCI AMERICA
For experimental / research use only.
2,6-Dimethylpyrazine >98.0%(GC)(T)
Tengzhou Jitian Aroma Chemiclal
2,6-Dimethyl Pyrazine
Tengzhou Xiang Yuan Aroma Chemicals
2,6-Dimethyl Pyrazine
Tianjin Danjun International
2,6-Dimethylpyrazine
United International
2,6-Dimethyl Pyrazine Nat.
United International
2,6-Dimethyl Pyrazine
Vigon International
Dimethyl-2,6 Pyrazine
WholeChem
2,6-Dimethylpyrazine
Synonyms   Articles   Notes   Search   Top
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 10 - Flammable.
R 22 - Harmful if swallowed.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  880 mg/kg
Drug and Chemical Toxicology. Vol. 3, Pg. 249, 1980.

intraperitoneal-mouse LD50  1080 mg/kg
Toxicology and Applied Pharmacology. Vol. 17, Pg. 244, 1970.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for 2,6-dimethyl pyrazine usage levels up to:
  0.0500 % in the fragrance concentrate.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 1.30 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 2.00 (μg/capita/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 5. Update in publication number(s): 29
Click here to view publication 5
 average usual ppmaverage maximum ppm
baked goods: 10.0000010.00000
beverages(nonalcoholic): 10.0000010.00000
beverages(alcoholic): 0.100005.00000
breakfast cereal: 10.0000010.00000
cheese: --
chewing gum: --
condiments / relishes: 10.0000010.00000
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: 10.0000010.00000
fruit ices: --
gelatins / puddings: 10.0000010.00000
granulated sugar: --
gravies: 10.0000010.00000
hard candy: 10.0000010.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 10.0000010.00000
milk products: 10.0000010.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: 10.0000010.00000
soups: 10.0000010.00000
sugar substitutes: --
sweet sauces: --
Synonyms   Articles   Notes   Search   Top
Safety References:
Flavor & Extract Manufacturers Association (FEMA) reference(s):
The FEMA GRAS assessment of pyrazine derivatives used as flavor ingredients. View pdf
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Flavouring Group Evaluation 17 (FGE.17): Pyrazine derivatives from chemical group 24 (Commission Regulation (EC) No 1565/2000 of 18 July 2000)
View page or View pdf
Flavouring Group Evaluation 50 (FGE.50): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17 (2005) (Commission Regulation (EC) No 1565/2000 of 18 July 2000) - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC)
View page or View pdf
Flavouring Group Evaluation 17, Revision 1 (FGE.17Rev1): Pyrazine derivatives from chemical group 24 - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) [1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2): Pyrazine derivatives from chemical group 24
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 50, Revision 1 (FGE.50Rev1): Consideration of pyrazine derivatives evaluated by JECFA (57th meeting) structurally related to pyrazine derivatives evaluated by EFSA in FGE.17Rev2 (2010)
View page or View pdf
Safety and efficacy of pyrazine derivatives including saturated ones belonging to chemical group 24 when used as flavourings for all animal species
View page or View pdf
EPI System: View
Chemical Carcinogenesis Research Information System: Search
EPA Substance Registry Services (TSCA): 108-50-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 7938
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 1325
WGK Germany: 3
 2,6-dimethylpyrazine
Chemidplus: 0000108509
RTECS: UQ2975000 for cas# 108-50-9
Synonyms   Articles   Notes   Search   Top
References:
 2,6-dimethylpyrazine
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 108-50-9
Pubchem (cid): 7938
Pubchem (sid): 134970522
Flavornet: 108-50-9
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS): View
CHEBI: View
HMDB (The Human Metabolome Database): HMDB35248
FooDB: FDB013908
YMDB (Yeast Metabolome Database): YMDB01600
Export Tariff Code: 2933.59.9500
Typical G.C.
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
For Odor
No odor group found for these
4-hydroxymethyl-pyridine 
2-methyl-3-pentyl pyrazine 
 sulfuryl octanoateFL/FR
 butyl decanoateFL/FR
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
 sulfuryl propionateFL/FR
animal
5-methyl-7(H)-cyclopenta[b]pyrazine 
balsamic
 guaiacyl phenyl acetateFL/FR
 guaiyl acetateFL/FR
bready
 coffee furanoneFL/FR
 furfuralFL/FR
 rum etherFL/FR
caramellic
 ethyl cyclopentenoloneFL/FR
 fenugreek absoluteFL/FR
 fenugreek oleoresinFL/FR
 maltolFL/FR
 shoyu furanoneFL/FR
 toffee furanoneFL/FR
 chocolate pyrazine AFL/FR
 cocoa hexenalFL/FR
2,5-dimethyl pyrazineFL/FR
2-ethyl-3-methoxypyrazineFL/FR
 nutty pyrazineFL/FR
fermented
isoamyl alcoholFL/FR
floral
 champaca absoluteFR
 dimethyl benzyl carbinyl propionateFR
 geranyl formateFL/FR
alpha-isomethyl ionone (90% min.)FL/FR
 phenethyl isobutyrateFL/FR
 tea acetateFR
 tetrahydrolinaloolFL/FR
fruity
 heptyl butyrateFL/FR
green
2-heptyl furanFL/FR
 magnolia flower oilFL/FR
herbal
6-acetoxydihydrotheaspiraneFL/FR
 clary sage absoluteFL/FR
 clary sage oil franceFL/FR
licorice
sweet basil oleoresinFL/FR
 sulfurolFL/FR
 sulfuryl acetateFL/FR
minty
dextro-carvoneFL/FR
musty
2-acetyl pyrroleFL/FR
3-acetyl-2,5-dimethyl furanFL/FR
 menthofuranFL/FR
ketoisophoroneFL/FR
nutty
2-acetyl-3-ethyl pyrazineFL/FR
2-acetyl-3-methyl pyrazineFL/FR
3,6-cocoa pyrazineFL/FR
3,5-cocoa pyrazineFL/FR
2-ethyl pyrazineFL/FR
2-ethyl-4-methyl thiazoleFL/FR
 filbert heptenoneFL/FR
 filbert pyrazineFL/FR
2,6-lutidineFL/FR
2-methyl pyrazineFL/FR
2-methyl-3-(methyl thio) pyrazineFL/FR
 nutty quinoxalineFL/FR
 sesame absoluteFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
2,4,5-trimethyl oxazoleFL/FR
2,3,5-trimethyl pyrazineFL/FR
popcorn
2-acetyl pyrazineFL/FR
2-acetyl thiazoleFL/FR
roasted
2-acetyl-2-pyrroline 
spicy
 caraway seed oleoresinFL/FR
(-)-cubenolFL/FR
 furfuryl thioacetateFL/FR
tropical
 genet absoluteFL/FR
vegetable
 methionalFL/FR
 tetrahydrofurfuryl alcoholFL/FR
woody
 cyperus root oil (cyperus rotundus)FR
(-)-guaiolFR
laevo-glutamic acidCS
 
For Flavor
 
No flavor group found for these
6-acetoxydihydrotheaspiraneFL/FR
2-acetyl-2-pyrroline 
2-acetyl-6-methyl pyrazineFL
 benzyl methyl sulfideFL
 butyl decanoateFL/FR
2(4)-isobutyl-4(2),6-dimethyl dihydro-4H-1,3,5-dithiazineFL
 chocolate pyrazine AFL/FR
 chocolate pyrazine BFL
6,7-dihydro-2,3-dimethyl-5H-cyclopentapyrazineFL
 dimethyl dihydrocyclopentapyrazineFL
2,5-dimethyl thiazoleFL
2-ethyl-3-methoxypyrazineFL/FR
(Z+E)-5-ethyl-4-methyl-2-(2-butyl) thiazolineFL
(Z+E)-5-ethyl-4-methyl-2-(2-methyl propyl) thiazolineFL
2-formyl pyrroleFL
 green pea pyrazineFL
 guaiyl acetateFL/FR
 magnolia flower oilFL/FR
2-methoxy-3-propyl pyrazineFL
 methyl 2-(methyl thio) acetateFL
4-(methyl thio) butanolFL
2-methyl-2-thiazolineFL
2-methyl-3-(methyl thio) pyrazineFL/FR
5-methyl-7(H)-cyclopenta[b]pyrazine 
 sulfuryl butyrateFL/FR
 sulfuryl decanoateFL/FR
 sulfuryl hexanoateFL/FR
 sulfuryl isobutyrateFL/FR
 thiazoleFL
2,4-dimethyl-3-oxazolineFL
 sulfuryl formateFL
 sulfuryl octanoateFL/FR
 sulfuryl propionateFL/FR
1-(2-thienyl) butanoneFL
alliaceous
 dicyclohexyl disulfideFL
3-mercapto-2-pentanoneFL
2-methyl thioacetaldehydeFL
bready
2-propionyl thiazoleFL
brown
 fenugreek oleoresinFL/FR
 furfuralFL/FR
burnt
 furfuryl alcoholFL
 rum etherFL/FR
2,4,5-trimethyl oxazoleFL/FR
caramellic
 fenugreek absoluteFL/FR
 maltolFL/FR
 shoyu furanoneFL/FR
 toffee furanoneFL/FR
chemical
2,5-dimethyl furanFL
citrus
ketoisophoroneFL/FR
cocoa
 butyraldehydeFL
 cocoa hexenalFL/FR
coffee
 diisoamyl thiomalateFL
2,4-dimethyl thiazoleFL
2-ethyl-4-methyl thiazoleFL/FR
 methyl furfuryl thiolFL
corn chip
2-acetyl thiazoleFL/FR
2-acetyl-2-thiazolineFL
earthy
 difurfuryl sulfideFL
fatty
2-heptyl furanFL/FR
fishy
4,5-dimethyl thiazoleFL
floral
alpha-isomethyl ionone (90% min.)FL/FR
 tetrahydrolinaloolFL/FR
fusel
isoamyl alcoholFL/FR
green
 clary sage absoluteFL/FR
 geranyl formateFL/FR
 heptyl butyrateFL/FR
2-methyl-5-isopropyl pyrazineFL
 propylene glycol acetone ketalFL
hay
 genet absoluteFL/FR
hazelnut
4-hydroxymethyl-pyridine 
herbal
 clary sage oil franceFL/FR
honey
 phenethyl isobutyrateFL/FR
jammy
 ethyl cyclopentenoloneFL/FR
licorice
sweet basil oleoresinFL/FR
meaty
3-mercapto-2-butanoneFL
2-methyl 3-(methyl thio) furanFL
2-methyl-3-tetrahydrofuran thiolFL
2-pyridinyl methane thiolFL
 sulfurolFL/FR
 sulfuryl acetateFL/FR
metallic
2,5-dihydroxy-1,4-dithianeFL
milky
dextro,laevo-3-(methyl thio) butanoneFL
minty
dextro-carvoneFL/FR
musty
2,5-dimethyl pyrazineFL/FR
2-ethoxythiazoleFL
 menthofuranFL/FR
 propionaldehydeFL
2,3,5-trimethyl pyrazineFL/FR
nutty
2-acetyl pyrroleFL/FR
3-acetyl-2,5-dimethyl furanFL/FR
3-acetyl-2,5-dimethyl thiopheneFL
2-acetyl-3-ethyl pyrazineFL/FR
2-acetyl-3-methyl pyrazineFL/FR
3,6-cocoa pyrazineFL/FR
3,5-cocoa pyrazineFL/FR
 coffee furanoneFL/FR
3,5-diethyl-2-methyl pyrazineFL
2,5-diethyl-3-methyl pyrazineFL
2-ethyl pyrazineFL/FR
1-ethyl-2-acetyl pyrroleFL
2-ethyl-6-methyl pyrazineFL
 filbert heptenoneFL/FR
 filbert pyrazineFL/FR
2,6-lutidineFL/FR
2-methyl pyrazineFL/FR
2-methyl-3-pentyl pyrazine 
 nutty pyrazineFL/FR
 nutty quinoxalineFL/FR
 sesame absoluteFL/FR
 tetrahydrofurfuryl alcoholFL/FR
2,3,5,6-tetramethyl pyrazineFL/FR
phenolic
 guaiacyl phenyl acetateFL/FR
popcorn
2-propionyl-2-thiazolineFL
radish
3-(methyl thio) propyl mercaptoacetateFL
roasted
2-acetyl pyrazineFL/FR
 ethyl 3-(furfuryl thio) propionateFL
 furfuryl thioacetateFL/FR
spicy
 caraway seed oleoresinFL/FR
(-)-cubenolFL/FR
sulfurous
2,3-butane dithiolFL
 methyl 2-methyl-3-furyl disulfideFL
3-methyl-2-butane thiolFL
 potato butanoneFL
tomato
 methionalFL/FR
vegetable
 potato butyraldehydeFL
waxy
 furfuryl octanoateFL
winey
5-ethyl-2-methyl pyridineFL
yeasty
 faex extractsFL
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
 beef roasted beefFL
 breadFL
 chocolate cocoaFL
 coffeeFR
 fried 
 mapleFR
 nutFL
 tobaccoFR
 vegetableFL
 yeastFL
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 beef roasted beef
Search  PMC Picture
 beer
Search  PMC Picture
 bread white bread
Search  PMC Picture
 coffee roasted coffee
Search  PMC Picture
 fenugreek seed
Search Trop  Picture
 garlic bulb
Search Trop  Picture
 kohlrabi stem
Search Trop  Picture
 lavender oil spike spain @ 0.310%
Data  GC  Search Trop  Picture
 potato chip
Search  PMC Picture
 tea
Search Trop  Picture
 whiskey
Search  Picture
Synonyms   Articles   Notes   Search   Top
Synonyms:
2,6-dimethyl paradiazine
2,6-dimethyl piazine
2,6-dimethyl pyrazine, kosher
2,6-dimethyl-1,4-diazine
 dimethyl-2,6 pyrazine
2,6-dimethylparadiazine
2,6-dimethylpiazine
2,6-dimethylpyrazine
2,6 dimethylpyrazine
3,5-dimethylpyrazine
2-methyl-6-methylpyrazine
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Determination of the alkylpyrazine composition of coffee using stable isotope dilution-gas chromatography-mass spectrometry (SIDA-GC-MS).
J-Stage: Chemical Profiles of Methylpyrazines Contained in Commercially Available Natto
PubMed: Pyrazine analogues are active components of wolf urine that induce avoidance and freezing behaviours in mice.
J-Stage: Quantitative Analysis of Alkylpyrazines in Regular- and Low-fat Commercial Peanut Butter Preparations
PubMed: Mechanistic elucidation of linker and ancillary ligand substitution reactions in Pt(II) dinuclear complexes.
PubMed: Bis(cyanato-ÎșN)tetra-kis-(2,6-dimethyl-pyrazine-ÎșN(4))nickel(II).
PubMed: Desalination of fish sauce by electrodialysis: effect on selected aroma compounds and amino acid compositions.
PubMed: Identification of 2-ethyl-4-methyl-3-thiazoline and 2-isopropyl-4-methyl-3-thiazoline for the first time in nature by the comprehensive analysis of sesame seed oil.
PubMed: Alkylpyrazines and other volatiles in cocoa liquors at pH 5 to 8, by Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS).
PubMed: Temporal changes of flavour and texture in cooked bologna type sausages as affected by fat and salt content.
PubMed: Bioconversion of 2,6-dimethylpyridine to 6-methylpicolinic acid by Exophiala dermatitidis (Kano) de Hoog DA5501 cells grown on n-dodecane.
PubMed: Coffee aroma--statistical analysis of compositional data.
PubMed: Syntheses, structures, and photoluminescence of a series of silver(I) sulfonates with pyrazine derivatives.
PubMed: Suppression of blood lipid concentrations by volatile Maillard reaction products.
PubMed: Bis(2,6-dimethyl-pyrazine-ÎșN)diiodidozinc(II).
PubMed: Competition between photochemistry and energy transfer in UV-excited diazabenzenes. 4. UV photodissociation of 2,3-, 2,5-, and 2,6-dimethylpyrazine.
PubMed: Structural study of silver(I) sulfonate complexes with pyrazine derivatives.
PubMed: Effect of ripening time and rearing system on amino acid-related flavour compounds of Iberian ham.
PubMed: Degradation of 2,5-dimethylpyrazine by Rhodococcus erythropolis strain DP-45 isolated from a waste gas treatment plant of a fishmeal processing company.
PubMed: Characterization of aroma compounds of chinese "Wuliangye" and "Jiannanchun" liquors by aroma extract dilution analysis.
PubMed: Determination of the 2H/1H and 15N/14N ratios of Alkylpyrazines from coffee beans (Coffea arabica L. and Coffea canephoravar. robusta) by isotope ratio mass spectrometry.
PubMed: Aroma compounds in sweet whey powder.
PubMed: Pyrazine derivatives in cigarette smoke inhibit hamster oviductal functioning.
PubMed: [Chemical profiles of methylpyrazines contained in commercially available natto].
PubMed: Identification of aroma compounds in Parmigiano-Reggiano cheese by gas chromatography/olfactometry.
PubMed: Effects of carnosine on volatile generation from Maillard reaction of ribose and cysteine.
PubMed: Effect of urea on volatile generation from Maillard reaction of cysteine and ribose.
PubMed: Chemical and sensory properties of liquid beet sugar.
PubMed: Pyrazine formation from serine and threonine.
PubMed: Effects of roasting on pyrazine contents and oxidative stability of red pepper seed oil prior to its extraction.
PubMed: Quantitative analysis of alkylpyrazines in regular- and low-fat commercial peanut butter preparations.
PubMed: Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test.
PubMed: Headspace constituents of opium.
PubMed: Effects of dimethylpyrazine isomers on reproductive and accessory reproductive organs in male rats.
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